Lista de obras - Fernando Danilo González Nilo

2D Autocorrelation, CoMFA, and CoMSIA modeling of protein tyrosine kinases' inhibition by substituted pyrido[2,3-d]pyrimidine derivatives.

artículo científico publicado en 2007

A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues.

artículo científico publicado en 2008

A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels

artículo científico publicado en 2020

Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase. Mutagenesis at metal site 1.

artículo científico publicado en 2004

Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase: mutagenesis at metal site 2

scientific article published on 01 August 2003

Antioxidant reactivity toward nitroxide probes anchored into human serum albumin. A new model for studying antioxidant repairing capacity of protein radicals

artículo científico publicado en 2009

Biomimetics: From Bioinformatics to Rational Design of Dendrimers as Gene Carriers.

artículo científico publicado en 2015

Biosynthesis of methoxypyrazines: elucidating the structural/functional relationship of two Vitis viniferaO-methyltransferases capable of catalyzing the putative final step of the biosynthesis of 3-alkyl-2-methoxypyrazine.

artículo científico publicado en 2011

Calculating Position-Dependent Diffusivity in Biased Molecular Dynamics Simulations

artículo científico publicado en 2013

Computationally efficient methodology for atomic-level characterization of dendrimer-drug complexes: a comparison of amine- and acetyl-terminated PAMAM.

artículo científico publicado en 2013

Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant

artículo científico publicado en 2015

Distinct roles of the last transmembrane domain in controlling Arabidopsis K+ channel activity.

artículo científico publicado en 2009

Distributed structures underlie gating differences between the kin channel KAT1 and the Kout channel SKOR.

artículo científico publicado en 2009

Docking and quantitative structure-activity relationship studies for the bisphenylbenzimidazole family of non-nucleoside inhibitors of HIV-1 reverse transcriptase

artículo científico publicado en 2008

Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures

artículo científico publicado en 2020

Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake.

artículo científico publicado en 2016

Effective pore size and radius of capture for K(+) ions in K-channels.

artículo científico publicado en 2016

Evaluation by site-directed mutagenesis of active site amino acid residues of Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase.

artículo científico publicado en 2002

Experimental and theoretical binding affinity between polyvinylpolypyrrolidone and selected phenolic compounds from food matrices

artículo científico publicado en 2014

Gating of a pH-Sensitive K2P Potassium Channel by an Electrostatic Effect of Basic Sensor Residues on the Selectivity Filter ⬇️

artículo científico publicado el 25 de enero de 2011

Gating of two-pore domain K+ channels by extracellular pH

artículo científico publicado en 2006

Histidine triad-like motif of the rotavirus NSP2 octamer mediates both RTPase and NTPase activities

artículo científico publicado en 2006

Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel.

artículo científico publicado en 2015

Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel

artículo científico publicado en 2015

Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish

artículo científico publicado en 2014

In silico analysis of putative paralytic shellfish poisoning toxins export proteins in cyanobacteria

artículo científico publicado en 2013

Insight into the Properties of Cardiolipin Containing Bilayers from Molecular Dynamics Simulations, Using a Hybrid All-Atom/United-Atom Force Field

artículo científico publicado en 2012

Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels

artículo científico publicado en 2015

Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block.

artículo científico publicado en 2008

Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenolpyruvate carboxykinase determined by fluorescence spectroscopy

artículo científico publicado en 2002

Location of TEMPO derivatives in micelles: subtle effect of the probe orientation

artículo científico publicado en 2015

Lysine 213 and histidine 233 participate in Mn(II) binding and catalysis in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

artículo científico publicado en 2002

Mechanistic Studies on the Self-Assembly of PLGA Patchy Particles and Their Potential Applications in Biomedical Imaging

artículo científico publicado en 2016

Molecular basis of drug resistance in A/H1N1 virus

artículo científico publicado en 2012

Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels

artículo científico publicado en 2014

Molecular modeling of the complexes between Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase and the ATP analogs pyridoxal 5'-diphosphoadenosine and pyridoxal 5'-triphosphoadenosine. Specific labeling of lysine 290

artículo científico publicado en 2000

Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity

artículo científico publicado en 2001

Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology ⬇️

artículo científico publicado el 11 de mayo de 2011

PAMAM G4 dendrimers as inhibitors of the iron storage properties of human L-chain ferritin

artículo científico publicado en 2015

Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells.

artículo científico publicado en 2013

Penicillium purpurogenum produces two GH family 43 enzymes with β-xylosidase activity, one monofunctional and the other bifunctional: Biochemical and structural analyses explain the difference.

artículo científico publicado en 2013

Photophysics and photochemistry of dyes bound to human serum albumin are determined by the dye localization.

artículo científico publicado en 2009

Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels.

artículo científico publicado en 2015

Putative binding mode of Escherichia coli exopolyphosphatase and polyphosphates based on a hybrid in silico/biochemical approach

artículo científico publicado en 2016

Quantitative structure-activity relationship of rubiscolin analogues as delta opioid peptides using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA).

artículo científico publicado en 2007

Rational discovery of new capsaicin analogues as TRPV1 activators

artículo científico publicado en 2015

Relevance of Arg457 for the nucleotide affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

artículo científico publicado en 2008

Relevance of phenylalanine 216 in the affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase for Mn(II).

artículo científico publicado en 2007

Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implication in membrane fusion

artículo científico publicado en 2008

Role of the histidine triad-like motif in nucleotide hydrolysis by the rotavirus RNA-packaging protein NSP2.

artículo científico publicado en 2003

Self-Assembly Behavior of Amphiphilic Janus Dendrimers in Water: A Combined Experimental and Coarse-Grained Molecular Dynamics Simulation Approach.

artículo científico publicado en 2018

Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

artículo científico publicado en 2016

Shared and group-specific features of the rotavirus RNA polymerase reveal potential determinants of gene reassortment restriction.

artículo científico publicado en 2009

Site-directed mutagenesis study of the microenvironment characteristics of Lys213 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

artículo científico publicado en 2006

Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase

artículo científico publicado en 2011

Stretch-Induced Activation of Pannexin 1 Channels Can Be Prevented by PKA-Dependent Phosphorylation

artículo científico publicado en 2020

Structural requirements of pyrido[2,3-d]pyrimidin-7-one as CDK4/D inhibitors: 2D autocorrelation, CoMFA and CoMSIA analyses

artículo científico publicado en 2008

Structure-antioxidant activity relationships of flavonoids isolated from the resinous exudate of Heliotropium sinuatum

artículo científico publicado en 2005

Study of the interaction between progesterone and beta-cyclodextrin by electrochemical techniques and steered molecular dynamics

artículo científico publicado en 2008

Substrate binding to fluorescent labeled wild type, Lys213Arg, and HIS233Gln Saccharomyces cerevisiae phosphoenolpyruvate carboxykinases

artículo científico publicado en 2004

Surface characterization of poly(4-vinylpyridine) quaternized with tetradecyl bromide: effect of the degree of quaternization

artículo científico publicado en 2004

Synthesis and characterization of an insoluble polymer based on polyamidoamine: applications for the decontamination of metals in aqueous systems.

artículo científico publicado en 2014

Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO-B Inhibitors

artículo científico publicado en 2014

The C-terminal regions have an important role in the activity of the ferroxidase center and the stability of Chlorobium tepidum ferritin.

artículo científico publicado en 2014

The molecular nature of the 17β-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel β1 subunit

artículo científico publicado en 2019

The pH sensor of the plant K+-uptake channel KAT1 is built from a sensory cloud rather than from single key amino acids

artículo científico publicado en 2012

Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability

artículo científico publicado en 2002

pH-dependent nano-capturing of tartaric acid using dendrimers

artículo científico publicado en 2014

β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel

artículo científico publicado en 2016

Lista de obras de Fernando Danilo González Nilo

2D Autocorrelation, CoMFA, and CoMSIA modeling of protein tyrosine kinases' inhibition by substituted pyrido[2,3-d]pyrimidine derivatives.

A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues.

A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels

Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase. Mutagenesis at metal site 1.

Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase: mutagenesis at metal site 2

Antioxidant reactivity toward nitroxide probes anchored into human serum albumin. A new model for studying antioxidant repairing capacity of protein radicals

Biomimetics: From Bioinformatics to Rational Design of Dendrimers as Gene Carriers.

Biosynthesis of methoxypyrazines: elucidating the structural/functional relationship of two Vitis viniferaO-methyltransferases capable of catalyzing the putative final step of the biosynthesis of 3-alkyl-2-methoxypyrazine.

Calculating Position-Dependent Diffusivity in Biased Molecular Dynamics Simulations

Computationally efficient methodology for atomic-level characterization of dendrimer-drug complexes: a comparison of amine- and acetyl-terminated PAMAM.

Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant

Distinct roles of the last transmembrane domain in controlling Arabidopsis K+ channel activity.

Distributed structures underlie gating differences between the kin channel KAT1 and the Kout channel SKOR.

Docking and quantitative structure-activity relationship studies for the bisphenylbenzimidazole family of non-nucleoside inhibitors of HIV-1 reverse transcriptase

Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures

Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake.

Effective pore size and radius of capture for K(+) ions in K-channels.

Evaluation by site-directed mutagenesis of active site amino acid residues of Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase.

Experimental and theoretical binding affinity between polyvinylpolypyrrolidone and selected phenolic compounds from food matrices

Gating of a pH-Sensitive K2P Potassium Channel by an Electrostatic Effect of Basic Sensor Residues on the Selectivity Filter ⬇️

Gating of two-pore domain K+ channels by extracellular pH

Histidine triad-like motif of the rotavirus NSP2 octamer mediates both RTPase and NTPase activities

Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel.

Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel

Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish

In silico analysis of putative paralytic shellfish poisoning toxins export proteins in cyanobacteria

Insight into the Properties of Cardiolipin Containing Bilayers from Molecular Dynamics Simulations, Using a Hybrid All-Atom/United-Atom Force Field

Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels

Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block.

Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenolpyruvate carboxykinase determined by fluorescence spectroscopy

Location of TEMPO derivatives in micelles: subtle effect of the probe orientation

Lysine 213 and histidine 233 participate in Mn(II) binding and catalysis in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

Mechanistic Studies on the Self-Assembly of PLGA Patchy Particles and Their Potential Applications in Biomedical Imaging

Molecular basis of drug resistance in A/H1N1 virus

Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels

Molecular modeling of the complexes between Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase and the ATP analogs pyridoxal 5'-diphosphoadenosine and pyridoxal 5'-triphosphoadenosine. Specific labeling of lysine 290

Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity

Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology ⬇️

PAMAM G4 dendrimers as inhibitors of the iron storage properties of human L-chain ferritin

Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells.

Penicillium purpurogenum produces two GH family 43 enzymes with β-xylosidase activity, one monofunctional and the other bifunctional: Biochemical and structural analyses explain the difference.

Photophysics and photochemistry of dyes bound to human serum albumin are determined by the dye localization.

Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels.

Putative binding mode of Escherichia coli exopolyphosphatase and polyphosphates based on a hybrid in silico/biochemical approach

Quantitative structure-activity relationship of rubiscolin analogues as delta opioid peptides using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA).

Rational discovery of new capsaicin analogues as TRPV1 activators

Relevance of Arg457 for the nucleotide affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

Relevance of phenylalanine 216 in the affinity of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase for Mn(II).

Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implication in membrane fusion

Role of the histidine triad-like motif in nucleotide hydrolysis by the rotavirus RNA-packaging protein NSP2.

Self-Assembly Behavior of Amphiphilic Janus Dendrimers in Water: A Combined Experimental and Coarse-Grained Molecular Dynamics Simulation Approach.

Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

Shared and group-specific features of the rotavirus RNA polymerase reveal potential determinants of gene reassortment restriction.

Site-directed mutagenesis study of the microenvironment characteristics of Lys213 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase

Stretch-Induced Activation of Pannexin 1 Channels Can Be Prevented by PKA-Dependent Phosphorylation

Structural requirements of pyrido[2,3-d]pyrimidin-7-one as CDK4/D inhibitors: 2D autocorrelation, CoMFA and CoMSIA analyses

Structure-antioxidant activity relationships of flavonoids isolated from the resinous exudate of Heliotropium sinuatum

Study of the interaction between progesterone and beta-cyclodextrin by electrochemical techniques and steered molecular dynamics

Substrate binding to fluorescent labeled wild type, Lys213Arg, and HIS233Gln Saccharomyces cerevisiae phosphoenolpyruvate carboxykinases

Surface characterization of poly(4-vinylpyridine) quaternized with tetradecyl bromide: effect of the degree of quaternization

Synthesis and characterization of an insoluble polymer based on polyamidoamine: applications for the decontamination of metals in aqueous systems.

Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO-B Inhibitors

The C-terminal regions have an important role in the activity of the ferroxidase center and the stability of Chlorobium tepidum ferritin.

The molecular nature of the 17β-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel β1 subunit

The pH sensor of the plant K+-uptake channel KAT1 is built from a sensory cloud rather than from single key amino acids

Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability

pH-dependent nano-capturing of tartaric acid using dendrimers

β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel