Lista de obras - Debby Laukens - Dominio Público Uruguay

A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach

artículo científico publicado en 2013

Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury

artículo científico publicado en 2010

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential

artículo científico publicado en 2015

Altered gut transcriptome in spondyloarthropathy

artículo científico publicado en 2006

Association between ASCA-positivity and carrier of a CARD-15 mutation in patients with Crohn's disease.

artículo científico publicado en 2003

Boosting the hypoxia-induced adaptive response in inflammatory bowel disease: a novel concept of treatment

artículo científico publicado en 2010

Butyrate-producing bacteria supplemented in vitro to Crohn's disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

artículo científico publicado en 2017

CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease

artículo científico publicado en 2004

CARD15 polymorphisms are associated with anti-Saccharomyces cerevisiae antibodies in caucasian Crohn's disease patients

artículo científico publicado en 2005

CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease

artículo científico publicado en 2007

Cellular diversity in the colon: another brick in the wall

scientific article published on 01 July 2019

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

artículo científico publicado en 2015

Common variants at five new loci associated with early-onset inflammatory bowel disease

artículo científico publicado en 2009

Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment

artículo científico publicado en 2011

Detection and Manipulation of the Stress Response Protein Metallothionein

artículo científico publicado en 2017

Detrimental shifts in microbial communities from inflammatory bowel disease patients upon selective pressures.

artículo científico publicado en 2011

Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn's disease/infectious colitis and healthy controls

artículo científico publicado en 2013

Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease

artículo científico publicado en 2010

Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

artículo científico publicado en 2014

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Evidence for a potential role of metallothioneins in inflammatory bowel diseases

artículo científico publicado en 2009

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis

artículo científico publicado en 2010

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

artículo científico publicado en 2014

Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease

artículo científico publicado en 2015

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

artículo científico publicado en 2008

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

artículo científico publicado en 2010

Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis

artículo científico publicado en 2014

Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design

artículo científico publicado en 2016

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

artículo científico publicado en 2012

Human metallothionein expression under normal and pathological conditions: mechanisms of gene regulation based on in silico promoter analysis

artículo científico publicado en 2009

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

artículo científico publicado en 2010

Incidence, Prevention and Management of Anti-Drug Antibodies Against Therapeutic Antibodies in Inflammatory Bowel Disease: A Practical Overview.

artículo científico publicado en 2017

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

artículo científico publicado en 2018

Interindividual differences in response to treatment with butyrate-producing Butyricicoccus pullicaecorum 25-3T studied in an in vitro gut model

artículo científico publicado en 2015

Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia.

artículo científico publicado en 2011

Intrarectal nitric oxide administration prevents cellular infiltration but not colonic injury during dextran sodium sulfate colitis

artículo científico publicado en 2012

Inverse correlation between metallothioneins and hypoxia-inducible factor 1 alpha in colonocytes and experimental colitis

artículo científico publicado en 2011

Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?

artículo científico publicado en 2011

Longitudinal quantification of inflammation in the murine dextran sodium sulfate-induced colitis model using μPET/CT.

artículo científico publicado en 2010

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Metallothionein and stress combine to affect multiple organ systems

artículo científico publicado en 2014

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

artículo científico publicado en 2014

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma.

artículo científico publicado en 2016

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

artículo científico publicado en 2007

Novel development in extraintestinal manifestations and spondylarthropathy

scientific article published on April 2011

Oral supplementation with sulodexide inhibits neo-angiogenesis in a rat model of peritoneal perfusion

artículo científico publicado en 2011

Pharmacologic activation of tumor hypoxia: a means to increase tumor 2-deoxy-2-[18F]fluoro-D-glucose uptake?

artículo científico publicado en 2013

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

artículo científico publicado en 2016

Radiological sacroiliitis is linked with CARD15 gene polymorphisms in patients with Crohn's disease.

artículo científico publicado en 2004

Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease

artículo científico publicado en 2004

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

artículo científico publicado en 2011

Role of metallothioneins as danger signals in the pathogenesis of colitis

artículo científico publicado en 2014

Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension

artículo científico publicado en 2009

Subclinical gut inflammation in spondyloarthritis is associated with a pro-angiogenic intestinal mucosal phenotype

artículo científico publicado en 2011

T84 monolayers are superior to Caco-2 as a model system of colonocytes.

artículo científico publicado en 2017

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

artículo científico publicado en 2015

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

artículo científico publicado en 2014

The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice

artículo científico publicado en 2015

The paradox of the unfolded protein response in cancer

artículo científico publicado en 2013

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

artículo científico publicado en 2014

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor

artículo científico publicado en 2017

Tumor PD-L1 status and CD8+ tumor-infiltrating T cells: markers of improved prognosis in oropharyngeal cancer

artículo científico publicado en 2017

Unmet Needs in IBD: the Case of Fatigue.

artículo científico publicado en 2017

Validated High Resolution Mass Spectrometry-Based Approach for Metabolomic Fingerprinting of the Human Gut Phenotype.

artículo científico publicado en 2015

Lista de obras de Debby Laukens

A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach

Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential

Altered gut transcriptome in spondyloarthropathy

Association between ASCA-positivity and carrier of a CARD-15 mutation in patients with Crohn's disease.

Boosting the hypoxia-induced adaptive response in inflammatory bowel disease: a novel concept of treatment

Butyrate-producing bacteria supplemented in vitro to Crohn's disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease

CARD15 polymorphisms are associated with anti-Saccharomyces cerevisiae antibodies in caucasian Crohn's disease patients

CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease

Cellular diversity in the colon: another brick in the wall

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

Common variants at five new loci associated with early-onset inflammatory bowel disease

Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment

Detection and Manipulation of the Stress Response Protein Metallothionein

Detrimental shifts in microbial communities from inflammatory bowel disease patients upon selective pressures.

Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn's disease/infectious colitis and healthy controls

Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease

Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Evidence for a potential role of metallothioneins in inflammatory bowel diseases

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis

Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Human metallothionein expression under normal and pathological conditions: mechanisms of gene regulation based on in silico promoter analysis

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

Incidence, Prevention and Management of Anti-Drug Antibodies Against Therapeutic Antibodies in Inflammatory Bowel Disease: A Practical Overview.

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

Interindividual differences in response to treatment with butyrate-producing Butyricicoccus pullicaecorum 25-3T studied in an in vitro gut model

Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia.

Intrarectal nitric oxide administration prevents cellular infiltration but not colonic injury during dextran sodium sulfate colitis

Inverse correlation between metallothioneins and hypoxia-inducible factor 1 alpha in colonocytes and experimental colitis

Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?

Longitudinal quantification of inflammation in the murine dextran sodium sulfate-induced colitis model using μPET/CT.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Metallothionein and stress combine to affect multiple organ systems

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma.

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

Novel development in extraintestinal manifestations and spondylarthropathy

Oral supplementation with sulodexide inhibits neo-angiogenesis in a rat model of peritoneal perfusion

Pharmacologic activation of tumor hypoxia: a means to increase tumor 2-deoxy-2-[18F]fluoro-D-glucose uptake?

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

Radiological sacroiliitis is linked with CARD15 gene polymorphisms in patients with Crohn's disease.

Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

Role of metallothioneins as danger signals in the pathogenesis of colitis

Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension

Subclinical gut inflammation in spondyloarthritis is associated with a pro-angiogenic intestinal mucosal phenotype

T84 monolayers are superior to Caco-2 as a model system of colonocytes.

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice

The paradox of the unfolded protein response in cancer

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor

Tumor PD-L1 status and CD8+ tumor-infiltrating T cells: markers of improved prognosis in oropharyngeal cancer

Unmet Needs in IBD: the Case of Fatigue.

Validated High Resolution Mass Spectrometry-Based Approach for Metabolomic Fingerprinting of the Human Gut Phenotype.