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Lista de obras de Maria Grazia De Simoni

2-Aminotetraline derivative protects from ischemia/reperfusion brain injury with a broad therapeutic window

artículo científico publicado en 2006

A New Surface Plasmon Resonance Assay for In Vitro Screening of Mannose-Binding Lectin Inhibitors.

artículo científico publicado en 2016

A close look at brain dynamics: cells and vessels seen by in vivo two-photon microscopy

artículo científico

Activation of the hypothalamic serotoninergic system by central interleukin-1.

artículo científico publicado en 1991

Acute hypertension induces oxidative stress in brain tissues

artículo científico publicado en 2006

Aging prolongs the stress-induced release of noradrenaline in rat hypothalamus

artículo científico publicado en 1993

Alzheimer's disease: another target for heparin therapy.

artículo científico publicado en 2009

Arterially perfused neurosphere-derived cells distribute outside the ischemic core in a model of transient focal ischemia and reperfusion in vitro

artículo científico publicado en 2008

Aspartame and the rat brain monoaminergic system.

artículo científico publicado en 1988

Basal and stress-induced release of noradrenaline in hypothalamus of spontaneously hypertensive rats at different ages.

artículo científico publicado en 1994

Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma

artículo científico publicado en 2014

C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice

artículo científico publicado en 2009

C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation

artículo científico publicado en 2005

CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents

artículo científico publicado en 2011

CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice.

artículo científico publicado en 2013

Cerebrospinal fluid pentraxin 3 early after subarachnoid hemorrhage is associated with vasospasm.

artículo científico publicado en 2010

Changes in the serotonergic system during the sleep-wake cycle: simultaneous polygraphic and voltammetric recordings in hypothalamus using a telemetry system.

artículo científico publicado en 1994

Cholinergic control of catechol metabolism in the rat locus coeruleus as studied by in vivo voltammetry

artículo científico publicado en 1983

Combined Genetic Deletion of IL (Interleukin)-4, IL-5, IL-9, and IL-13 Does Not Affect Ischemic Brain Injury in Mice

artículo científico publicado en 2019

Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating

artículo científico publicado en 2015

Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury.

artículo científico

Dexamethasone Conjugation to Biodegradable Avidin-Nucleic-Acid-Nano-Assemblies Promotes Selective Liver Targeting and Improves Therapeutic Efficacy in an Autoimmune Hepatitis Murine Model

scientific article published on 18 March 2019

Differences in the effect of the antidepressant amineptine on striatal and limbic DOPAC measured by HPLC-ECD and in vivo voltammetry

artículo científico publicado en 1986

Different effects of fenfluramine isomers and metabolites on extracellular 5-HIAA in nucleus accumbens and hippocampus of freely moving rats

artículo científico publicado en 1988

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies

artículo científico publicado en 2016

Direct reprogramming of human bone marrow stromal cells into functional renal cells using cell-free extracts

artículo científico publicado en 2015

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

artículo científico publicado en 2016

Effect of traumatic brain injury on cognitive function in mice lacking p55 and p75 tumor necrosis factor receptors.

artículo científico publicado en 2008

Evidence for a different sensitivity to various central effects of interleukin-1 beta in mice

artículo científico publicado en 1992

Ficolin-3-mediated lectin complement pathway activation in patients with subarachnoid hemorrhage

artículo científico publicado en 2013

Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice

artículo científico publicado en 2015

Functional and histological consequences of quinolinic and kainic acid-induced seizures on hippocampal somatostatin neurons

artículo científico publicado en 1991

Functional meaning of tryptophan-induced increase of 5-HT metabolism as clarified by in vivo voltammetry

artículo científico publicado en 1987

Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis

artículo científico publicado en 2002

Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development

artículo científico publicado en 2003

Glial cells drive preconditioning-induced blood-brain barrier protection.

artículo científico publicado en 2011

Glutamate release in the nucleus tractus solitarius induced by peripheral lipopolysaccharide and interleukin-1 beta.

artículo científico publicado en 1998

Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production.

artículo científico publicado en 2011

HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.

artículo científico publicado en 2006

Heart-fatty acid-binding and tau proteins relate to brain injury severity and long-term outcome in subarachnoid haemorrhage patients

artículo científico publicado en 2013

Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro.

artículo científico publicado en 2002

Human brain trauma severity is associated with lectin complement pathway activation

artículo científico publicado en 2018

Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma.

artículo científico publicado en 2011

Hypothalamic serotonergic activity correlates better with brain temperature than with sleep-wake cycle and muscle tone in rats

artículo científico publicado en 1999

Imaging T-cell movement in the brain during experimental cerebral malaria.

artículo científico publicado en 2009

Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain

artículo científico publicado en 2013

Impaired central stress-induced release of noradrenaline in rats with heart failure: a microdialysis study

artículo científico publicado en 2002

In vivo studies on the enhancement of serotonin reuptake by tianeptine

artículo científico publicado en 1992

Induction of a transmissible tau pathology by traumatic brain injury

scientific article published on 01 September 2018

Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus

article

Inflammatory response and glia activation in developing rat hippocampus after status epilepticus

artículo científico publicado en 2005

Interaction between serotonergic and dopaminergic systems detected in striatum by differential pulse voltammetry

artículo científico publicado en 1985

Interleukin-6, tumor necrosis factor and corticosterone induction by central lipopolysaccharide in aged rats

scientific article published on 01 January 1997

Internalization of nanopolymeric tracers does not alter characteristics of placental cells.

artículo científico publicado en 2016

Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6.

artículo científico publicado en 1990

Intracerebroventricular injection of the terminal complement complex causes inflammatory reaction in the rat brain

artículo científico publicado en 2003

Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice

artículo científico publicado en 2017

Lack of glucocorticoids sustains the stress-induced release of noradrenaline in the anterior hypothalamus.

artículo científico publicado en 1993

Lectin Complement Pathway and Its Bloody Interactions in Brain Ischemia

artículo científico publicado en 2016

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques

artículo científico publicado en 2017

Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

artículo científico publicado en 2008

Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).

artículo científico publicado en 1999

Long-lasting protection in brain trauma by endotoxin preconditioning

artículo científico publicado en 2011

Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury

artículo científico publicado en 2016

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

artículo científico publicado en 2016

Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

artículo científico publicado en 2018

Mannose-binding lectin has a direct deleterious effect on ischemic brain microvascular endothelial cells

scientific article published on 07 September 2019

Mannose-binding lectin is expressed after clinical and experimental traumatic brain injury and its deletion is protective

artículo científico publicado en 2014

Miniaturized optoelectronic system for telemetry of in vivo voltammetric signals

artículo científico publicado en 1990

Multiple and complex effects of buspirone on central dopaminergic system

artículo científico publicado en 1988

Nerve growth factor and transforming growth factor-beta serum levels in acute stroke patients. Possible involvement of neurotrophins in cerebrovascular disease

artículo científico publicado en 2001

Neuroprotective effect of C1-inhibitor following traumatic brain injury in mice.

artículo científico publicado en 2008

Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment.

artículo científico publicado en 2007

Peripheral Inflammatory Response in Alzheimer's Disease and Multiinfarct Dementia

artículo científico publicado en 2002

Peripheral interleukin-6 administration increases extracellular concentrations of serotonin and the evoked release of serotonin in the rat striatum

artículo científico publicado en 2001

Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease.

artículo científico publicado en 2004

Permissive role of glucocorticoids on interleukin-1 activation of the hypothalamic serotonergic system

artículo científico publicado en 1994

Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury.

artículo científico publicado en 2016

Prophylactic but not delayed administration of simvastatin protects against long-lasting cognitive and morphological consequences of neonatal hypoxic-ischemic brain injury, reduces interleukin-1beta and tumor necrosis factor-alpha mRNA induction, an

artículo científico publicado en 2003

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites.

artículo científico publicado en 2016

Proteomic analysis of mouse brain cortex identifies metabolic down-regulation as a general feature of ischemic pre-conditioning

artículo científico publicado en 2012

Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures

article

Recombinant C1 inhibitor in brain ischemic injury.

artículo científico publicado en 2009

Response by Perego et al to Letter Regarding Article, "Combined Genetic Deletion of IL (Interleukin)-4, IL-5, IL-9, and IL-13 Does Not Affect Ischemic Brain Injury in Mice"

scientific article published on 27 September 2019

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.

artículo científico publicado en 2015

SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance

scientific article published on 23 March 2019

Scaffold Optimisation of Tetravalent Antagonists of the Mannose Binding Lectin.

artículo científico publicado en 2015

Selective inhibition of plasma kallikrein protects brain from reperfusion injury

artículo científico publicado en 2006

Serotonin uptake inhibition: in vivo effect of sertraline in rats

artículo científico publicado en 1992

Similarities and differences between D-ALA2 MET5 enkephalin amide and morphine in the induction of tolerance to their effects on catalepsy and on dopamine metabolism in the rat brain.

artículo científico publicado en 1982

Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat.

artículo científico publicado en 2005

Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury.

artículo científico publicado en 2017

Six-month ischemic mice show sensorimotor and cognitive deficits associated with brain atrophy and axonal disorganization

artículo científico publicado en 2013

Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury

scientific article published on 09 April 2019

THE EFFECT OF ETHER LIPID 1-O-OCTADECYL-2-O-METHOXY-RAC-GLYCERO-3-PHOSPHOCHOLINE AND ITS ANALOGUES PLATELET ACTIVATING FACTOR AND CARBAMYL-PLATELET ACTIVATING FACTOR ON THE BIOSYNTHESIS OF INTERLEUKIN-6 IN HUMAN THYMIC EPITHELIAL CELLS CULTIVATED IN

artículo científico publicado en 1996

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role

scientific article published on 28 October 2020

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.

artículo científico publicado en 2016

Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.

artículo científico publicado en 2012

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

artículo científico publicado en 2011

The effect of opiate treatment on the postdecapitation reflex and monoamine metabolism in the rat spinal cord

artículo científico publicado en 1983

The genetics of small-vessel disease.

artículo científico publicado en 2012

The inflammatory response in cerebral ischemia: focus on cytokines in stroke patients

artículo científico publicado en 2002

The ischemic environment drives microglia and macrophage function

artículo científico publicado en 2015

The phagocytic state of brain myeloid cells after ischemia revealed by superresolution structured illumination microscopy

artículo científico publicado en 2019

The sympathetic nervous system tonically inhibits peripheral interleukin-1beta and interleukin-6 induction by central lipopolysaccharide.

artículo científico publicado en 1998

Three-dimensional confocal analysis of microglia/macrophage markers of polarization in experimental brain injury

artículo científico publicado en 2013

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors

artículo científico publicado en 2005

Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis

artículo científico publicado en 2014

and evidence of dopaminergic system down regulation induced by chronic L-DOPA

artículo científico publicado el 28 de mayo de 1984

c-Jun N-terminal kinase pathway activation in human and experimental cerebral contusion.

artículo científico publicado en 2009

β-AMYLOID FRAGMENT POTENTIATES IL-6 AND TNF-α SECRETION BY LPS IN ASTROCYTES BUT NOT IN MICROGLIA

artículo científico publicado en 1997