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Lista de obras de Percy A Knolle

"To Be or Not to Be": Immune Tolerance in Chronic Hepatitis B.

artículo científico publicado en 2016

A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection

artículo científico publicado en 2001

A human schwannoma cell line supports the in vitro adhesion of Plasmodium falciparum infected erythrocytes to chondroitin-4-sulfate.

artículo científico publicado en 2002

A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells

artículo científico publicado en 2016

A soluble form of the adhesion receptor CD58 (LFA‐3) is present in human body fluids ⬇️

artículo científico publicado el 1 de noviembre de 1993

Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion

artículo científico publicado en 2013

Acute respiratory failure in tropical malaria during pregnancy. Successful treatment using extracorporeal CO2 elimination

artículo científico publicado en 1993

Adenosine regulates CD8 T-cell priming by inhibition of membrane-proximal T-cell receptor signalling

artículo científico publicado en 2009

Adoptive T-cell therapy to treat liver cancer: is the liver microenvironment key?

artículo científico publicado en 2013

Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention

scientific article published on 01 September 2019

Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances.

artículo científico publicado en 2016

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.

artículo científico publicado en 2010

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.

artículo científico publicado en 2016

Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis

artículo científico publicado en 2014

Antigen delivery via hydrophilic PEG-b-PAGE-b-PLGA nanoparticles boosts vaccination induced T cell immunity

artículo científico publicado en 2016

Antigen-presenting cell function in the tolerogenic liver environment.

artículo científico publicado en 2010

Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells

artículo científico publicado en 1996

Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms.

artículo científico publicado en 2013

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation.

artículo científico publicado en 2009

B7-H1 Selectively Controls TH17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway.

artículo científico publicado en 2015

B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis

artículo científico publicado en 2008

Batf3-dependent dendritic cells in the renal lymph node induce tolerance against circulating antigens.

artículo científico publicado en 2013

Bioluminescence imaging allows measuring CD8 T cell function in the liver

artículo científico publicado en 2010

Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro.

artículo científico publicado en 2007

Brucellosis: differential diagnosis of acute abdominal pain.

artículo científico publicado en 1993

CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.

artículo científico publicado en 2012

Checkpoint Inhibition in Head and Neck Cancer: Immune Therapeutic Options, Limitations, and Beyond.

artículo científico publicado en 2017

Circulating ICAM-1 (sCD54) and LFA-3 (sCD58) in chronic hepatitis B--a longitudinal study in patients treated with interferon-alpha.

artículo científico publicado en 1997

Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3.

artículo científico publicado en 2011

Complete congenital heart block in autoimmune hepatitis (SLA-positive)

artículo científico publicado en 1994

Control of immune responses by savenger liver endothelial cells.

artículo científico publicado en 2003

CpG-ODN-induced inflammation is sufficient to cause T-cell-mediated autoaggression against hepatocytes

artículo científico publicado en 2002

Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance

artículo científico publicado en 2006

Cross-presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance

artículo científico publicado en 2005

Cross-priming in health and disease.

artículo científico publicado en 2010

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium

artículo científico publicado en 2014

Cyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells.

artículo científico publicado en 2016

Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver

article

Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis.

artículo científico publicado en 2015

Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes

artículo científico publicado en 2005

Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells.

artículo científico publicado en 2009

Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.

artículo científico publicado en 2007

Dynamic Regulation of CD8 T Cell Tolerance Induction by Liver Sinusoidal Endothelial Cells

artículo científico publicado en 2010

Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

artículo científico publicado en 2000

Elevated serum E-selectin in patients with liver metastases of colorectal cancer

artículo científico publicado en 1996

Endothelial cell-mediated uptake of a hepatitis B virus: a new concept of liver targeting of hepatotropic microorganisms

artículo científico publicado en 2001

Endotoxin down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells

artículo científico publicado en 1999

Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting.

artículo científico publicado en 2008

Evaluation of the role of the endocytic receptor L-SIGN for cytoadhesion of Plasmodium falciparum-infected erythrocytes

artículo científico publicado en 2005

Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.

artículo científico publicado en 2011

Fms-like tyrosine kinase 3 receptor ligand (Flt3L)-based vaccination administered with an adenoviral vector prevents tumor growth of colorectal cancer in a BALB/c mouse model

artículo científico publicado en 2013

Four-and-a-half LIM domain protein 2 is a novel regulator of sphingosine 1-phosphate receptor 1 in CCL19-induced dendritic cell migration.

artículo científico publicado en 2010

Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice

artículo científico publicado en 2012

Functional classification of memory CD8(+) T cells by CX3CR1 expression

artículo científico publicado en 2015

Global transcriptional characterization of CD8+ T cell memory

artículo científico

Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis.

artículo científico publicado en 2016

HIV and pregnancy: risks of transmission and therapeutic possibilities

artículo científico publicado en 1996

Hepatic immune regulation and its involvement in viral hepatitis infection.

artículo científico

Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium.

artículo científico publicado en 2009

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.

artículo científico publicado en 2013

Hitting the right button: MAVS-mediated defense against HAV infection.

artículo científico publicado en 2016

Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge

article

IAP antagonization promotes inflammatory destruction of vascular endothelium

artículo científico publicado en 2015

IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules

artículo científico publicado en 1998

IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function

artículo científico publicado en 2014

Immediate antigen-specific effector functions by TCR-transgenic CD8+ NKT cells

artículo científico publicado en 2006

Immunological functions of liver sinusoidal endothelial cells

artículo científico publicado en 2016

Immunomodulatory effects of the liver: deletion of activated CD4+ effector cells and suppression of IFN-gamma-producing cells after intravenous protein immunization

artículo científico publicado en 2002

In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration

artículo científico publicado en 2012

In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma

artículo científico publicado en 2006

Inactivated ORF virus shows antifibrotic activity and inhibits human hepatitis B virus (HBV) and hepatitis C virus (HCV) replication in preclinical models

artículo científico publicado en 2013

Inactivated Orf virus (Parapoxvirus ovis) elicits antifibrotic activity in models of liver fibrosis.

artículo científico publicado en 2012

Inactivated orf virus (Parapoxvirus ovis) induces antitumoral activity in transplantable tumor models.

artículo científico publicado en 2011

Inactivated parapoxvirus ovis (Orf virus) has antiviral activity against hepatitis B virus and herpes simplex virus

artículo científico publicado en 2003

Induction of murine liver damage by overexpression of CD40 ligand provides an experimental model to study fulminant hepatic failure.

artículo científico publicado en 2006

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Interfering with Kupffer cell replenishment: New insights into liver injury.

artículo científico publicado en 2018

Interleukin-10 expression is autoregulated at the transcriptional level in human and murine kupffer cells

artículo científico publicado en 1998

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection

artículo científico publicado en 2013

Involvement of the liver in the induction of CD8 T cell tolerance towards oral antigen.

artículo científico publicado en 2006

Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.

artículo científico publicado en 2010

Kidney dendritic cells induce innate immunity against bacterial pyelonephritis

artículo científico publicado en 2011

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

artículo científico publicado en 2017

Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection

artículo científico publicado en 2012

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

artículo científico publicado en 2012

Ligase chain reaction (LCR) assay for semi-quantitative detection of HBV DNA in mononuclear leukocytes of patients with chronic hepatitis B

scientific article published on 01 September 1996

Liver Sinusoidal Endothelial Cells Are Not Permissive for Adenovirus Type 5

artículo científico publicado en 2000

Liver X receptor activation promotes differentiation of regulatory T cells

artículo científico publicado en 2017

Liver macrophages in healthy and diseased liver

artículo científico publicado en 2017

Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2.

artículo científico publicado en 2016

Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time

artículo científico publicado en 2014

Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice

artículo científico publicado en 2012

Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells

scientific article published on 01 April 2008

Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity

artículo científico publicado en 2013

Living in the liver: hepatic infections

artículo científico publicado en 2012

MHC class II genes influence the susceptibility to chronic active hepatitis C ⬇️

artículo científico publicado el 1 de agosto de 1997

Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4.

artículo científico publicado en 2016

Mechanisms balancing tolerance and immunity in the liver

artículo científico publicado en 2011

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

artículo científico publicado en 2014

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis ⬇️

artículo científico publicado el 1 de octubre de 2010

Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma.

artículo científico publicado en 2006

Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1.

artículo científico publicado en 2008

Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism.

artículo científico publicado en 2011

Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity

artículo científico publicado en 2018

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

artículo científico publicado en 2021

NF-kappa B antisense oligonucleotides reduce leukocyte-endothelial interaction in hepatic ischemia-reperfusion

scientific article published on 01 November 2001

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

artículo científico publicado en 2015

Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells.

artículo científico publicado en 2001

Normal interleukin-12 production in individuals with antibodies to Helicobacter pylori

artículo científico publicado en 1997

Nuclear receptors: TH17 cell control from within.

artículo científico publicado en 2011

Osteoimmunological mechanisms involved in orthodontically and bacterially induced periodontal stress

artículo científico publicado en 2012

Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes

artículo científico publicado en 2018

Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis

artículo científico publicado en 2018

Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy

artículo científico publicado en 2007

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

artículo científico publicado en 2019

Primary tumor-associated expression of CXCR4 predicts formation of local and systemic recurrency in head and neck squamous cell carcinoma.

artículo científico publicado en 2017

Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients

artículo científico publicado en 2005

Prolonged IKKβ Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells.

artículo científico publicado en 2017

Prominent regulatory but weak antigen-presenting cell function of hepatic stellate cells

artículo científico publicado en 2011

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Quantification and genotyping of serum HCV-RNA in patients with chronic hepatitis C undergoing interferon treatment ⬇️

artículo científico publicado el 1 de enero de 1997

Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction

artículo científico publicado en 2017

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

artículo científico publicado en 2012

Rapid and preferential distribution of blood-borne alphaCD3epsilonAb to the liver is followed by local stimulation of T cells and natural killer T cells

Rare pre-core stop-codon mutant nt. 1897 predominates over wide-spread mutant nt. 1896 in an unusual course of chronic hepatitis B.

artículo científico publicado en 1996

Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

artículo científico publicado en 2005

Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10

article

Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal

scientific article published on 23 April 2020

Regulatory role of periodontal ligament fibroblasts for innate immune cell function and differentiation

scientific article published on 21 March 2012

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

artículo científico publicado en 2011

Rescue of T-cell function during persistent pulmonary adenoviral infection by TLR9 activation.

artículo científico publicado en 2017

STAT5 is an ambivalent regulator of neutrophil homeostasis

artículo científico publicado en 2007

Scaling of immune responses against intracellular bacterial infection

artículo científico

Semiquantitative assessment of pre-core stop-codon mutant and wildtype hepatitis B virus during the course of chronic hepatitis B using a new PCR-based assay

artículo científico publicado en 1996

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

artículo científico publicado en 2016

Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection. ⬇️

artículo científico publicado en 2019

Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment

artículo científico publicado en 2019

Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates

artículo científico publicado en 2015

Staying local-antigen presentation in the liver

artículo científico publicado en 2016

Steady-state cross-presentation of OVA is mannose receptor-dependent but inhibitable by collagen fragments

artículo científico publicado en 2010

Sustained elimination of hepatitis B virus from serum induced in a patient with chronic hepatitis B and advanced human immunodeficiency virus infection

artículo científico publicado en 1994

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

artículo científico publicado en 2019

Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow.

artículo científico publicado en 2016

Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization

artículo científico publicado en 2009

Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO.

artículo científico publicado en 2006

T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.

artículo científico publicado en 2013

T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract.

artículo científico publicado en 2010

TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.

artículo científico publicado en 2017

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice.

artículo científico publicado en 2015

TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation

article by Dirk Wohlleber et al published September 2012 in Cell Reports

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

scientific article published on 17 June 2019

Taking off the brakes: T cell immunity in the liver.

artículo científico publicado en 2010

Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.

scientific article published on 07 March 2017

Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination

artículo científico publicado en 2017

The IDO1-induced kynurenines play a major role in the antimicrobial effect of human myeloid cells against Listeria monocytogenes

artículo científico publicado en 2013

The PDL1-inducible GTPase Arl4d controls T effector function by limiting IL-2 production

artículo científico publicado en 2018

The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes.

artículo científico publicado en 2012

The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib.

artículo científico publicado en 2016

The liver's imprint on CD8⁺ T cell priming

artículo científico publicado en 2012

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

artículo científico publicado en 2009

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

article published in 2009

The role of hepatic immune regulation in systemic immunity to viral infection

artículo científico publicado en 2014

Therapeutic immunomodulation using a virus--the potential of inactivated orf virus.

artículo científico publicado en 2012

Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice

artículo científico publicado en 2014

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12

scientific article published on 01 April 1996

Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance

article

Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors

artículo científico publicado en 2012

Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection

artículo científico publicado en 2014

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

artículo científico publicado en 2015

Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation

artículo científico publicado en 2016

Transfer of HBV Genomes Using Low Doses of Adenovirus Vectors Leads to Persistent Infection in Immune Competent Mice

scientific article published on 14 March 2012

Transfer of T cell surface molecules to dendritic cells upon CD4+ T cell priming involves two distinct mechanisms

scientific article published on 01 September 2008

Transgenic overexpression of Tcfap2c/AP-2gamma results in liver failure and intestinal dysplasia

artículo científico publicado en 2011

Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection

artículo científico publicado en 2016

Viral and host factors in the prediction of response to interferon-alpha therapy in chronic hepatitis C after long-term follow-up

artículo científico publicado en 1998

Virally Infected Mouse Liver Endothelial Cells Trigger CD8+ T-Cell Immunity

[Histopathological research laboratories in translational research : Conception and integration into the infrastructure of pathological institutes]

artículo científico publicado en 2019

[The complement system and its possible role in the pathogenesis of age-related macular degeneration (AMD)]

artículo científico publicado en 2005

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