Lista de obras - Santos Fustero - Dominio Público Uruguay

1,4-Benzodiazepine N-nitrosoamidines: useful intermediates in the synthesis of tricyclic benzodiazepines.

artículo científico publicado en 2006

1,7-octadiene-assisted tandem multicomponent cross-enyne metathesis (CEYM)-Diels-Alder reactions: a useful alternative to Mori's conditions

artículo científico publicado en 2012

A New Strategy for the Synthesis of Optically Pure β-Fluoroalkyl β-Amino Acid Derivatives

artículo científico publicado en 2009

A Versatile Approach to CF3 -Containing 2-Pyrrolidones by Tandem Michael Addition-Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors.

artículo científico publicado en 2015

A concise, asymmetric synthesis of tetramic acid derivatives

artículo científico publicado en 2002

A novel and selective fluoride opening of aziridines by XtalFluor-E. synthesis of fluorinated diamino acid derivatives

artículo científico publicado en 2015

A practical entry to β-aryl-β-alkyl amino alcohols: application to the synthesis of a potent BACE1 inhibitor.

artículo científico publicado en 2012

A versatile synthesis of fluorinated uracils in solution and on solid-phase.

artículo científico publicado en 2004

An Efficient and Simple Entry to N-Substituted beta-Enamino Acid Derivatives from 2-Alkyl-2-oxazolines and 2-Alkyl-2-thiazolines

scientific article published on 01 December 1996

An efficient entry to optically active anti- and syn-beta-amino-alpha-trifluoromethyl alcohols

scientific article published on 23 January 2008

Anionic-anionic asymmetric tandem reactions: one-pot synthesis of optically pure fluorinated indolines from 2-p-tolylsulfinyl alkylbenzenes

artículo científico publicado en 2008

Asymmetric Synthesis of Fluorinated Amino Macrolactones through Ring-Closing Metathesis

artículo científico publicado en 2007

Asymmetric Synthesis of Fluorinated Cyclic β-Amino Acid Derivatives through Cross Metathesis

artículo científico publicado en 2006

Asymmetric Synthesis of Fluorinated Isoindolinones through Palladium-Catalyzed Carbonylative Amination of Enantioenriched Benzylic Carbamates

scientific article published on 29 June 2015

Asymmetric Synthesis of New β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives

artículo científico publicado en 2006

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

artículo científico publicado en 2014

Asymmetric allylation/ring closing metathesis: one-pot synthesis of benzo-fused cyclic homoallylic amines. Application to the formal synthesis of Sertraline derivatives.

artículo científico publicado en 2013

Asymmetric intramolecular aza-Michael reaction in desymmetrization processes. Total synthesis of hippodamine and epi-hippodamine.

artículo científico publicado en 2015

Asymmetric synthesis of indolines through intramolecular shifting of aromatic sulfinyl groups. Role of the pi,pi-stacking interactions in these unusual S(N)Ar processes.

artículo científico publicado en 2009

Asymmetric synthesis of quaternary α-amino acid derivatives and their fluorinated analogues

artículo científico publicado en 2011

AuX3-mediated selective head-to-head dimerization of difluoropropargyl amides

artículo científico publicado en 2009

Base-dependent stereodivergent intramolecular aza-Michael reaction: asymmetric synthesis of 1,3-disubstituted isoindolines.

artículo científico publicado en 2013

Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation

artículo científico publicado en 2014

Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

artículo científico publicado en 2019

Chiral Monofluorobenzyl Carbanions: Synthesis of Enantiopure β‐Fluorinated β‐Phenylethylamines

artículo científico publicado en 2011

Concise preparation of 2,2-difluorohomopropargyl carbonyl derivatives. Application to the synthesis of 4,4-difluoroisoquinolinone congeners

artículo científico publicado en 2008

Cross-metathesis reactions as an efficient tool in the synthesis of fluorinated cyclic beta-amino acids

artículo científico publicado en 2009

Design, synthesis, and biological evaluation of novel fluorinated ethanolamines.

artículo científico publicado en 2011

Diastereodivergent Synthesis of Fluorinated Cyclic β(3)-Amino Acid Derivatives

artículo científico publicado en 2015

Diastereoselective Synthesis of Fluorinated, Seven-Membered β-Amino Acid Derivatives via Ring-Closing Metathesis

artículo científico publicado en 2003

Diastereoselective intramolecular additions of allyl- and propargylsilanes to iminium ions: synthesis of cyclic and bicyclic quaternary amino acids

artículo científico publicado en 2010

Diastereoselective synthesis of 2-phenyl-3-(trifluoromethyl)piperazines as building blocks for drug discovery

artículo científico publicado en 2014

Efficacy and activity prediction by molecular topology of new drugs against the Tetranychus urticae plague.

artículo científico publicado en 2013

Enantioselective Palladium-Catalyzed Oxidative β,β-Fluoroarylation of α,β-Unsaturated Carbonyl Derivatives.

artículo científico publicado en 2016

Enantioselective organocatalytic intramolecular aza-Michael reaction: a concise synthesis of (+)-sedamine, (+)-allosedamine, and (+)-coniine

scientific article published on 07 November 2007

Enantioselective synthesis of fluorinated alpha-amino acids and derivatives in combination with ring-closing metathesis: intramolecular pi-stacking interactions as a source of stereocontrol

artículo científico publicado en 2001

FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status.

artículo científico publicado en 2009

Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.

artículo científico publicado en 2017

Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence

artículo científico publicado en 2017

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

artículo científico publicado en 2013

Fluorous (trimethylsilyl)ethanol: a new reagent for carboxylic acid tagging and protection in peptide synthesis.

artículo científico publicado en 2006

Fluorous TBAF: a convenient and selective reagent for fluoride-mediated deprotections

artículo científico publicado en 2009

Gold catalyzed stereoselective tandem hydroamination-formal aza-Diels-Alder reaction of propargylic amino esters

artículo científico publicado en 2013

Gold-catalyzed intramolecular hydroamination of o-alkynylbenzyl carbamates: a route to chiral fluorinated isoindoline and isoquinoline derivatives

artículo científico publicado en 2013

Gold-catalyzed tandem hydroamination/formal aza-Diels-Alder reaction of homopropargyl amino esters: a combined computational and experimental mechanistic study

scientific article published on 20 February 2015

Highly enantioselective synthesis of fluorinated gamma-amino alcohols through proline-catalyzed cross-Mannich reaction

artículo científico publicado en 2005

Highly stereoselective tandem aza-Michael addition-enolate protonation to form partially modified retropeptide mimetics incorporating a trifluoroalanine surrogate

artículo científico publicado en 2003

Improved regioselectivity in pyrazole formation through the use of fluorinated alcohols as solvents: synthesis and biological activity of fluorinated tebufenpyrad analogs.

artículo científico publicado en 2008

Intramolecular Michael reaction of tert-butylsulfinyl ketimines: asymmetric synthesis of 3-substituted indanones

scientific article published on 23 November 2011

Intramolecular Nitrone Cycloaddition of α-(Trifluoromethyl)styrenes. Role of the CF3 Group in the Regioselectivity

artículo científico publicado en 2017

Intramolecular hydroamination of difluoropropargyl amides: regioselective synthesis of fluorinated beta- and gamma-lactams

artículo científico publicado en 2007

Metal-Free and User-Friendly Regioselective Hydroxyfluorination of Olefins.

artículo científico publicado en 2018

Microwave-assisted organocatalytic enantioselective intramolecular aza-Michael reaction with α,β-unsaturated ketones

scientific article published on 14 November 2011

Microwave-assisted tandem cross metathesis intramolecular Aza-Michael reaction: an easy entry to cyclic beta-amino carbonyl derivatives

scientific article published on 05 May 2007

Microwave-assisted tandem organocatalytic peptide-coupling intramolecular aza-Michael reaction: α,β-unsaturated N-acyl pyrazoles as Michael acceptors

artículo científico publicado en 2014

N-sulfinyl amines as a nitrogen source in the asymmetric intramolecular aza-Michael reaction: total synthesis of (-)-pinidinol

artículo científico publicado en 2010

New Strategies for the Synthesis of Fluorinated Vinylogous Amidines and beta-Enamino Ketones

artículo científico publicado en 1999

New cathepsin inhibitors to explore the fluorophilic properties of the S2 pocket of cathepsin B: design, synthesis, and biological evaluation

artículo científico publicado en 2011

New fluorinated peptidomimetics through tandem aza-michael addition to alpha-trifluoromethyl acrylamide acceptors: synthesis and conformational study in solid state and solution.

artículo científico publicado en 2009

New strategy for the stereoselective synthesis of fluorinated beta-amino acids

artículo científico publicado en 2002

Novel approach for asymmetric synthesis of fluorinated beta-amino sulfones and allylic amines

scientific article published on 01 July 2003

Olefin metathesis reactions with fluorinated substrates, catalysts, and solvents.

artículo científico publicado en 2014

One-pot cross-enyne metathesis (CEYM)-Diels-Alder reaction of gem-difluoropropargylic alkynes

artículo científico publicado en 2013

Organocatalytic approach to benzofused nitrogen-containing heterocycles: enantioselective total synthesis of (+)-angustureine

artículo científico publicado en 2008

Pauson-Khand reaction of fluorinated compounds

scientific article published on 14 July 2020

Recent advances in the synthesis of functionalised monofluorinated compounds

artículo científico publicado en 2018

Regio- and diastereoselective fluorination of alicyclic β-amino acids

artículo científico publicado en 2011

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

artículo científico publicado en 2010

Ring-opening metathesis of some strained bicyclic systems; stereocontrolled access to diolefinated saturated heterocycles with multiple stereogenic centers

scientific article published on 24 October 2018

Role of the gem-difluoro moiety in the tandem ring-closing metathesis-olefin isomerization: regioselective preparation of unsaturated lactams

artículo científico publicado en 2006

Selective formal transesterification of fluorinated 2-(trimethylsilyl)ethyl alpha-imino esters mediated by TBAF

scientific article published on 21 June 2008

Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms.

artículo científico publicado en 2015

Solution versus fluorous versus solid-phase synthesis of 2,5-disubstituted 1,3-azoles. Preliminary antibacterial activity studies

artículo científico publicado en 2009

Solution-, solid-phase, and fluorous synthesis of beta,beta-difluorinated cyclic quaternary alpha-amino acid derivatives: a comparative study.

artículo científico publicado en 2008

Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives

artículo científico publicado en 2012

Structure of 5-amino-1,3,4-thiadiazole-2-sulfonamide, an inhibitor of the enzyme carbonic anhydrase

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

artículo científico publicado en 2013

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

artículo científico publicado en 2013

Synthesis and biological evaluation of new bicyclic fluorinated uracils through ring-closing metathesis

artículo científico publicado en 2006

Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.

artículo científico publicado en 2009

Synthesis of 3-substituted isoindolin-1-ones via a tandem desilylation, cross-coupling, hydroamidation sequence under aqueous phase-transfer conditions

artículo científico publicado en 2015

Synthesis of new fluorinated Tebufenpyrad analogs with acaricidal activity through regioselective pyrazole formation.

artículo científico publicado en 2008

Synthetic and Biological Applications of Fluorous Reagents as Phase Tags ⬇️

artículo científico publicado el 1 de enero de 2012

Tandem Organocatalytic Cycloaromatization/Intramolecular Friedel-Crafts Alkylation Sequence for the Synthesis of Indolizinones and Pyrrolo-azepinone Derivatives

scientific article published on 12 August 2019

Tandem gold self-relay catalysis for the synthesis of 2,3-dihydropyridin-4(1 H)-ones: combination of σ and π Lewis acid properties of gold salts

artículo científico publicado en 2014

Tandem nucleophilic addition-intramolecular aza-Michael reaction: facile synthesis of chiral fluorinated isoindolines

artículo científico publicado en 2010

The Fluoro-Pauson-Khand Reaction in the Synthesis of Enantioenriched Nitrogenated Bicycles Bearing a Quaternary C-F Stereogenic Center

scientific article published on 03 September 2019

The role of fluorine in the stereoselective tandem aza-Michael addition to acrylamide acceptors: an experimental and theoretical mechanistic study

scientific article published on 01 January 2007

Tiratricol neutralizes bacterial endotoxins and reduces lipopolysaccharide-induced TNF-alpha production in the cell.

artículo científico publicado en 2008

Unique reactivity of fluorinated molecules with transition metals

artículo científico publicado en 2014

Vinyl Fluorides: Competent Olefinic Counterparts in the Intramolecular Pauson-Khand Reaction

artículo científico publicado en 2019

γ-Silylboronates in the chiral Brønsted acid-catalysed allylboration of aldehydes

artículo científico publicado en 2015

Lista de obras de Santos Fustero

1,4-Benzodiazepine N-nitrosoamidines: useful intermediates in the synthesis of tricyclic benzodiazepines.

1,7-octadiene-assisted tandem multicomponent cross-enyne metathesis (CEYM)-Diels-Alder reactions: a useful alternative to Mori's conditions

A New Strategy for the Synthesis of Optically Pure β-Fluoroalkyl β-Amino Acid Derivatives

A Versatile Approach to CF3 -Containing 2-Pyrrolidones by Tandem Michael Addition-Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors.

A concise, asymmetric synthesis of tetramic acid derivatives

A novel and selective fluoride opening of aziridines by XtalFluor-E. synthesis of fluorinated diamino acid derivatives

A practical entry to β-aryl-β-alkyl amino alcohols: application to the synthesis of a potent BACE1 inhibitor.

A versatile synthesis of fluorinated uracils in solution and on solid-phase.

An Efficient and Simple Entry to N-Substituted beta-Enamino Acid Derivatives from 2-Alkyl-2-oxazolines and 2-Alkyl-2-thiazolines

An efficient entry to optically active anti- and syn-beta-amino-alpha-trifluoromethyl alcohols

Anionic-anionic asymmetric tandem reactions: one-pot synthesis of optically pure fluorinated indolines from 2-p-tolylsulfinyl alkylbenzenes

Asymmetric Synthesis of Fluorinated Amino Macrolactones through Ring-Closing Metathesis

Asymmetric Synthesis of Fluorinated Cyclic β-Amino Acid Derivatives through Cross Metathesis

Asymmetric Synthesis of Fluorinated Isoindolinones through Palladium-Catalyzed Carbonylative Amination of Enantioenriched Benzylic Carbamates

Asymmetric Synthesis of New β,β-Difluorinated Cyclic Quaternary α-Amino Acid Derivatives

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

Asymmetric allylation/ring closing metathesis: one-pot synthesis of benzo-fused cyclic homoallylic amines. Application to the formal synthesis of Sertraline derivatives.

Asymmetric intramolecular aza-Michael reaction in desymmetrization processes. Total synthesis of hippodamine and epi-hippodamine.

Asymmetric synthesis of indolines through intramolecular shifting of aromatic sulfinyl groups. Role of the pi,pi-stacking interactions in these unusual S(N)Ar processes.

Asymmetric synthesis of quaternary α-amino acid derivatives and their fluorinated analogues

AuX3-mediated selective head-to-head dimerization of difluoropropargyl amides

Base-dependent stereodivergent intramolecular aza-Michael reaction: asymmetric synthesis of 1,3-disubstituted isoindolines.

Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation

Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

Chiral Monofluorobenzyl Carbanions: Synthesis of Enantiopure β‐Fluorinated β‐Phenylethylamines

Concise preparation of 2,2-difluorohomopropargyl carbonyl derivatives. Application to the synthesis of 4,4-difluoroisoquinolinone congeners

Cross-metathesis reactions as an efficient tool in the synthesis of fluorinated cyclic beta-amino acids

Design, synthesis, and biological evaluation of novel fluorinated ethanolamines.

Diastereodivergent Synthesis of Fluorinated Cyclic β(3)-Amino Acid Derivatives

Diastereoselective Synthesis of Fluorinated, Seven-Membered β-Amino Acid Derivatives via Ring-Closing Metathesis

Diastereoselective intramolecular additions of allyl- and propargylsilanes to iminium ions: synthesis of cyclic and bicyclic quaternary amino acids

Diastereoselective synthesis of 2-phenyl-3-(trifluoromethyl)piperazines as building blocks for drug discovery

Efficacy and activity prediction by molecular topology of new drugs against the Tetranychus urticae plague.

Enantioselective Palladium-Catalyzed Oxidative β,β-Fluoroarylation of α,β-Unsaturated Carbonyl Derivatives.

Enantioselective organocatalytic intramolecular aza-Michael reaction: a concise synthesis of (+)-sedamine, (+)-allosedamine, and (+)-coniine

Enantioselective synthesis of fluorinated alpha-amino acids and derivatives in combination with ring-closing metathesis: intramolecular pi-stacking interactions as a source of stereocontrol

FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status.

Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.

Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Fluorous (trimethylsilyl)ethanol: a new reagent for carboxylic acid tagging and protection in peptide synthesis.

Fluorous TBAF: a convenient and selective reagent for fluoride-mediated deprotections

Gold catalyzed stereoselective tandem hydroamination-formal aza-Diels-Alder reaction of propargylic amino esters

Gold-catalyzed intramolecular hydroamination of o-alkynylbenzyl carbamates: a route to chiral fluorinated isoindoline and isoquinoline derivatives

Gold-catalyzed tandem hydroamination/formal aza-Diels-Alder reaction of homopropargyl amino esters: a combined computational and experimental mechanistic study

Highly enantioselective synthesis of fluorinated gamma-amino alcohols through proline-catalyzed cross-Mannich reaction

Highly stereoselective tandem aza-Michael addition-enolate protonation to form partially modified retropeptide mimetics incorporating a trifluoroalanine surrogate

Improved regioselectivity in pyrazole formation through the use of fluorinated alcohols as solvents: synthesis and biological activity of fluorinated tebufenpyrad analogs.

Intramolecular Michael reaction of tert-butylsulfinyl ketimines: asymmetric synthesis of 3-substituted indanones

Intramolecular Nitrone Cycloaddition of α-(Trifluoromethyl)styrenes. Role of the CF3 Group in the Regioselectivity

Intramolecular hydroamination of difluoropropargyl amides: regioselective synthesis of fluorinated beta- and gamma-lactams

Metal-Free and User-Friendly Regioselective Hydroxyfluorination of Olefins.

Microwave-assisted organocatalytic enantioselective intramolecular aza-Michael reaction with α,β-unsaturated ketones

Microwave-assisted tandem cross metathesis intramolecular Aza-Michael reaction: an easy entry to cyclic beta-amino carbonyl derivatives

Microwave-assisted tandem organocatalytic peptide-coupling intramolecular aza-Michael reaction: α,β-unsaturated N-acyl pyrazoles as Michael acceptors

N-sulfinyl amines as a nitrogen source in the asymmetric intramolecular aza-Michael reaction: total synthesis of (-)-pinidinol

New Strategies for the Synthesis of Fluorinated Vinylogous Amidines and beta-Enamino Ketones

New cathepsin inhibitors to explore the fluorophilic properties of the S2 pocket of cathepsin B: design, synthesis, and biological evaluation

New fluorinated peptidomimetics through tandem aza-michael addition to alpha-trifluoromethyl acrylamide acceptors: synthesis and conformational study in solid state and solution.

New strategy for the stereoselective synthesis of fluorinated beta-amino acids

Novel approach for asymmetric synthesis of fluorinated beta-amino sulfones and allylic amines

Olefin metathesis reactions with fluorinated substrates, catalysts, and solvents.

One-pot cross-enyne metathesis (CEYM)-Diels-Alder reaction of gem-difluoropropargylic alkynes

Organocatalytic approach to benzofused nitrogen-containing heterocycles: enantioselective total synthesis of (+)-angustureine

Pauson-Khand reaction of fluorinated compounds

Recent advances in the synthesis of functionalised monofluorinated compounds

Regio- and diastereoselective fluorination of alicyclic β-amino acids

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

Ring-opening metathesis of some strained bicyclic systems; stereocontrolled access to diolefinated saturated heterocycles with multiple stereogenic centers

Role of the gem-difluoro moiety in the tandem ring-closing metathesis-olefin isomerization: regioselective preparation of unsaturated lactams

Selective formal transesterification of fluorinated 2-(trimethylsilyl)ethyl alpha-imino esters mediated by TBAF

Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms.

Solution versus fluorous versus solid-phase synthesis of 2,5-disubstituted 1,3-azoles. Preliminary antibacterial activity studies

Solution-, solid-phase, and fluorous synthesis of beta,beta-difluorinated cyclic quaternary alpha-amino acid derivatives: a comparative study.

Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives

Structure of 5-amino-1,3,4-thiadiazole-2-sulfonamide, an inhibitor of the enzyme carbonic anhydrase

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

Synthesis and biological evaluation of new bicyclic fluorinated uracils through ring-closing metathesis