Lista de obras - Michael D. B. Swedberg - Dominio Público Uruguay

1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists.

artículo científico publicado en 1998

3-(5-Alkylamino-4-isoxazolyl)-1,2,5,6-tetrahydropyridines: a novel class of central nicotinic receptor ligands.

artículo científico publicado en 1998

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.

artículo científico

A proactive nonclinical drug abuse and dependence liability assessment strategy: a sponsor perspective

artículo científico publicado en 2013

A repeated test procedure to assess onset and duration of the cue properties of (-) delta 9-THC, (-) delta 8-THC-DMH and (+) delta 8-THC.

artículo científico publicado en 1981

AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects.

artículo científico publicado en 2014

Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity

artículo científico publicado en 1998

Discriminative stimulus effects of intravenous l-nicotine and nicotine analogs or metabolites in squirrel monkeys

artículo científico publicado en 1989

Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils

artículo científico publicado en 1998

Discriminative stimulus properties of drugs: a brief history and a selective review.

artículo científico publicado en 1982

Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases

artículo científico publicado en 1986

Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse

artículo científico publicado en 2016

Effects of chlormethiazole (Heminevrin®) on drug discrimination and open-field behavior in gerbils ⬇️

artículo científico publicado el 31 de octubre de 1978

Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse

artículo científico publicado en 2014

Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat.

artículo científico publicado en 2013

Evidence supporting lack of discriminative stimulus properties of a combination of naltrexone and morphine

artículo científico publicado el 1 de abril de 1979

In vivo labeling of the central GABA uptake carrier with 3H-Tiagabine

artículo científico publicado el 1 de enero de 1992

Muscarinic agonists as analgesics. Antinociceptive activity versus M1 activity: SAR of alkylthio-TZTP's and related 1,2,5-thiadiazole analogs

artículo científico publicado en 1995

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice.

artículo científico publicado en 2000

NNC-19-1228 and NNC 22-0031, novel neuroleptics with a "mesolimbic-selective" behavioral profile

artículo científico publicado en 1997

Potential role of muscarinic receptors in schizophrenia

artículo científico publicado en 1999

Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor

artículo científico publicado en 2011

Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839.

artículo científico publicado en 2014

Reinforcing effects of nicotinic compounds: intravenous self-administration in drug-naive mice

artículo científico publicado en 1998

Role of central noradrenaline neurons in the contextual control of latent inhibition in taste aversion learning

artículo científico publicado en 1986

Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents.

artículo científico publicado en 1999

Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates

artículo científico publicado en 1999

Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives

artículo científico publicado en 2001

Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors

artículo científico publicado en 2001

The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats.

artículo científico publicado en 1992

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

artículo científico publicado en 2001

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane .

artículo científico publicado en 1998

mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties

artículo científico publicado en 2014

Lista de obras de Michael D. B. Swedberg

1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists.

3-(5-Alkylamino-4-isoxazolyl)-1,2,5,6-tetrahydropyridines: a novel class of central nicotinic receptor ligands.

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.

A proactive nonclinical drug abuse and dependence liability assessment strategy: a sponsor perspective

A repeated test procedure to assess onset and duration of the cue properties of (-) delta 9-THC, (-) delta 8-THC-DMH and (+) delta 8-THC.

AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects.

Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity

Discriminative stimulus effects of intravenous l-nicotine and nicotine analogs or metabolites in squirrel monkeys

Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils

Discriminative stimulus properties of drugs: a brief history and a selective review.

Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases

Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse

Effects of chlormethiazole (Heminevrin®) on drug discrimination and open-field behavior in gerbils ⬇️

Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse

Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat.

Evidence supporting lack of discriminative stimulus properties of a combination of naltrexone and morphine

In vivo labeling of the central GABA uptake carrier with 3H-Tiagabine

Muscarinic agonists as analgesics. Antinociceptive activity versus M1 activity: SAR of alkylthio-TZTP's and related 1,2,5-thiadiazole analogs

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice.

NNC-19-1228 and NNC 22-0031, novel neuroleptics with a "mesolimbic-selective" behavioral profile

Potential role of muscarinic receptors in schizophrenia

Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor

Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839.

Reinforcing effects of nicotinic compounds: intravenous self-administration in drug-naive mice

Role of central noradrenaline neurons in the contextual control of latent inhibition in taste aversion learning

Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents.

Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates

Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives

Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors

The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats.

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane .

mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties