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Lista de obras de Genevieve L. Evans

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket

artículo científico publicado en 2015

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel

artículo científico publicado en 2019

A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis.

artículo científico publicado en 2011

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

artículo científico publicado en 2014

Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design.

artículo científico

Conformational flexibility of EptA driven by an interdomain helix provides insights for enzyme-substrate recognition

artículo científico publicado en 2021

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2015

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis

artículo científico publicado en 2008

Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups

artículo científico publicado en 2017

Disrupting the quaternary structure of DHDPS as a new approach to antibiotic design. ⬇️

2010 doctoral thesis by Genevieve Laura Evans at University of Canterbury

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis

artículo científico publicado en 2012

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

scientific journal article

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site

artículo científico publicado en 2020

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

artículo científico publicado en 2013

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2014

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

artículo científico publicado en 2015

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

artículo científico publicado en 2017

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site

artículo científico publicado en 2015

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition

artículo científico publicado en 2013

Thermodynamics of the fragile X mental retardation protein RGG box interactions with G quartet forming RNA.

artículo científico publicado en 2006

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