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Lista de obras de Tuomo A Keinänen

A potential estrogen mimetic effect of a bis(ethyl)polyamine analogue on estrogen receptor positive MCF-7 breast cancer cells ⬇️

artículo científico publicado el 10 de agosto de 2011

Activation of Polyamine Catabolism by N¹,N-Diethylnorspermine in Hepatic HepaRG Cells Induces Dedifferentiation and Mesenchymal-Like Phenotype

Alpha-methyl polyamines: efficient synthesis and tolerance studies in vivo and in vitro. First evidence for dormant stereospecificity of polyamine oxidase

artículo científico publicado en 2006

Alpha-methylated polyamines as potential drugs and experimental tools in enzymology.

artículo científico publicado en 2007

Aminooxy analogues of spermidine evidence the divergent roles of the charged amino nitrogens in the cellular physiology of spermidine

scientific article published on 01 January 1995

Analysis of free, mono- and diacetylated polyamines from human urine by LC-MS/MS.

artículo científico publicado en 2013

Analysis of underivatized polyamines by reversed phase liquid chromatography with electrospray tandem mass spectrometry

artículo científico publicado en 2007

Animal disease models generated by genetic engineering of polyamine metabolism.

artículo científico publicado en 2005

Charge Deficient Analogues of the Natural Polyamines ⬇️

artículo científico publicado el 1 de enero de 2014

Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.

artículo científico publicado en 2012

Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults

artículo científico publicado en 2010

Cutaneous application of alpha-methylspermidine activates the growth of resting hair follicles in mice

artículo científico publicado en 2009

Disturbed keratinocyte differentiation in transgenic mice and organotypic keratinocyte cultures as a result of spermidine/spermine N-acetyltransferase overexpression.

artículo científico publicado en 2005

Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues.

artículo científico publicado en 2009

Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5A ⬇️

artículo científico publicado el 23 de agosto de 2011

Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.

artículo científico publicado en 2015

Methylated polyamines as research tools

artículo científico publicado en 2011

Mice with targeted disruption of spermidine/spermine N-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

artículo científico publicado en 2006

Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase

artículo científico publicado en 2007

Novel isosteric charge-deficient spermine analogue--1,12-diamino-3,6,9-triazadodecane: synthesis, pK(a) measurement and biological activity.

artículo científico publicado en 2009

Polyamine flux analysis by determination of heavy isotope incorporation from 13C, 15N-enriched amino acids into polyamines by LC-MS/MS

scientific article published on 05 August 2011

Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells.

artículo científico publicado en 2015

Quantitative determination of underivatized polyamines by using isotope dilution RP-LC-ESI-MS/MS.

artículo científico publicado en 2008

Role of hypusinated eukaryotic translation initiation factor 5A in polyamine depletion-induced cytostasis

artículo científico publicado en 2007

Selective regulation of polyamine metabolism with methylated polyamine analogues

artículo científico

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

artículo científico publicado en 2009

Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A.

artículo científico publicado en 2013

Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts

artículo científico publicado en 2009

Tissue-specific alternative splicing of spermidine/spermine N1-acetyltransferase

artículo científico publicado en 2011

Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives

scientific article published on 13 December 2019

activated polyamine catabolism in acute pancreatitis: alpha-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality.

artículo científico publicado en 2006

alpha-Methylspermidine protects against carbon tetrachloride-induced hepatic and pancreatic damage

artículo científico publicado en 2009

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