Lista de obras - Michael J. Quon - Dominio Público Uruguay

A Method of Delivering Dialysate of Constantly Decreasing Osmolality During Dialysis ⬇️

artículo científico publicado el 1 de noviembre de 1979

A mathematical model and computer simulation study of insulin receptor regulation

artículo científico publicado en 1991

A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.

artículo científico publicado en 2003

A phosphotyrosyl mimetic peptide reverses impairment of insulin-stimulated translocation of GLUT4 caused by overexpression of PTP1B in rat adipose cells

artículo científico publicado en 1999

ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development

artículo científico publicado en 2015

Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle

artículo científico publicado en 2016

Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients

artículo científico publicado en 2007

Additive beneficial effects of atorvastatin combined with amlodipine in patients with mild-to-moderate hypertension

artículo científico publicado en 2009

Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia

artículo científico publicado en 2005

Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients

artículo científico publicado en 2004

Adiponectin and cardiovascular disease: response to therapeutic interventions.

artículo científico publicado en 2007

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

artículo científico publicado en 2003

Amyloid beta oligomers induce impairment of neuronal insulin receptors

artículo científico publicado en 2007

Anti-inflammatory and metabolic effects of candesartan in hypertensive patients.

artículo científico publicado en 2005

Are statins effective for simultaneously treating dyslipidemias and hypertension?

artículo científico publicado en 2007

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases

artículo científico publicado en 2003

Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model

artículo científico publicado en 2005

Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia

artículo científico publicado en 2005

Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators.

artículo científico publicado en 2005

C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.

artículo científico publicado en 2009

Caveats to aggressive lowering of lipids by specific statins.

artículo científico publicado en 2011

Cellular Stress, Excessive Apoptosis, and the Effect of Metformin in a Mouse Model of Type 2 Diabetic Embryopathy

artículo científico publicado en 2015

Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells.

artículo científico publicado en 1996

Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.

artículo científico publicado en 2011

Combined therapy with ramipril and simvastatin has beneficial additive effects on tissue factor activity and prothrombin fragment 1+2 in patients with type 2 diabetes

scientific article published on 11 September 2006

Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice

artículo científico publicado en 2007

Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats.

scientific article published on 25 August 2009

Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.

artículo científico publicado en 2008

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

artículo científico publicado en 2007

Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium.

artículo científico publicado en 2005

Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy

artículo científico publicado en 2012

Differential metabolic effects of distinct statins.

artículo científico publicado en 2010

Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients.

artículo científico publicado en 2008

Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients.

artículo científico publicado en 2011

Distinct mechanisms for globular adiponectin that integrate vascular and metabolic actions of insulin to help maintain coordinated cardiovascular and glucose homeostasis.

artículo científico publicado en 2013

Dominant negative FADD dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy.

artículo científico publicado en 2015

Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin

artículo científico publicado en 1999

EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR.

artículo científico publicado en 2007

Effects of fenofibrate therapy on circulating adipocytokines in patients with primary hypertriglyceridemia

scientific article published on 29 October 2010

Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells

scientific article published on 01 September 1996

Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells ⬇️

artículo científico publicado el 30 de noviembre de 1997

Effects of simvastatin therapy on circulating adipocytokines in patients with hypercholesterolemia

artículo científico publicado en 2010

Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertension

artículo científico publicado en 2007

Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn.

artículo científico publicado en 2007

Escherichia coli K1 internalization via caveolae requires caveolin-1 and protein kinase Calpha interaction in human brain microvascular endothelial cells

artículo científico publicado en 2002

Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+.

artículo científico publicado en 2005

Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring

artículo científico publicado en 2016

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.

artículo científico publicado en 2015

Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes.

artículo científico publicado en 2013

Extracellular conversion of adiponectin hexamers into trimers

scientific journal article

FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity.

artículo científico publicado en 2006

G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis

artículo científico publicado en 2010

Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells

artículo científico publicado en 2006

Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.

artículo científico

Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1

artículo científico publicado en 2009

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases

artículo científico publicado en 2003

High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance

artículo científico publicado en 2005

Impaired insulin secretion in the Turner metabolic syndrome

artículo científico publicado en 2004

Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes.

artículo científico publicado en 2016

Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells

artículo científico publicado en 2001

Insulin action and insulin resistance in vascular endothelium.

artículo científico publicado en 2007

Insulin and the insulin receptor in experimental models of learning and memory.

artículo científico publicado en 2004

Insulin receptor binding kinetics: modeling and simulation studies

artículo científico publicado en 2000

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

artículo científico publicado en 2009

Insulin receptor substrate-2 (IRS-2) can mediate the action of insulin to stimulate translocation of GLUT4 to the cell surface in rat adipose cells.

artículo científico publicado en 1997

Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production.

artículo científico publicado en 2005

Insulin signal transduction pathways

artículo científico publicado en 1994

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

artículo científico publicado en 2001

Leptin and cardiovascular disease: response to therapeutic interventions

scientific article published on June 2008

Letter by Koh and Quon regarding article, "Evidence mandating earlier and more aggressive treatment of hypercholesterolemia".

artículo científico publicado en 2009

Letter re: Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation

artículo científico publicado en 2005

Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity

artículo científico publicado en 2001

MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness.

artículo científico

Man shall not live by bread alone.

artículo científico publicado en 2014

Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complications

artículo científico publicado en 2013

Modulation of adiponectin as a potential therapeutic strategy

artículo científico publicado en 2014

Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop

artículo científico publicado en 2003

Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10.

artículo científico publicado en 2003

New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate

artículo científico publicado en 2014

Obesity modifies the effects of the Asp905Tyr variant of PPP1R3A on risk of type 2 diabetes and insulin sensitivity

scientific article published on 01 September 2007

Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance or endothelial dysfunction in lean or obese subjects

artículo científico publicado en 2006

Overexpression of protein tyrosine phosphatase-alpha (PTP-alpha) but not PTP-kappa inhibits translocation of GLUT4 in rat adipose cells

artículo científico publicado en 1999

PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro.

artículo científico publicado en 2002

PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes

artículo científico publicado en 2002

PTEN does not modulate GLUT4 translocation in rat adipose cells under physiological conditions

artículo científico publicado en 2001

Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect

artículo científico publicado en 2003

Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor

artículo científico publicado en 2001

Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute [...]

artículo científico publicado en 2005

Potentially important considerations in choosing specific statin treatments to reduce overall morbidity and mortality.

artículo científico publicado en 2012

Predicted effects of hemoglobin A1c assay precision on a patient population distribution of serial hemoglobin A1c difference values.

artículo científico

Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA.

artículo científico publicado en 2010

Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes

scientific article published on 01 October 1999

Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin.

artículo científico publicado en 2000

Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling.

artículo científico publicado en 2008

Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

artículo científico publicado en 1997

QUICKI is a useful and accurate index of insulin sensitivity

artículo científico publicado en 2002

Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.

artículo científico publicado en 2000

Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction.

artículo científico publicado en 2007

Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.

artículo científico publicado en 2006

Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor

artículo científico publicado en 1998

Repeatability characteristics of simple indices of insulin resistance: implications for research applications

artículo científico publicado en 2001

Response to comment on Sarkar et al. Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes. Diabetes care 2014;37:666-670.

artículo científico publicado en 2014

Role of lipotoxicity in endothelial dysfunction

artículo científico publicado en 2012

Role of pleckstrin homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate 3.

artículo científico publicado en 2003

Role of renin-angiotensin system blockades in reciprocal relationship between insulin resistance and endothelial dysfunction

artículo científico publicado en 2010

S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2

artículo científico publicado en 2008

Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.

artículo científico publicado en 2002

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

artículo científico publicado en 2002

Significant differential effects of omega-3 fatty acids and fenofibrate in patients with hypertriglyceridemia.

artículo científico publicado en 2011

Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps.

artículo científico publicado en 2009

Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients

artículo científico publicado en 2008

SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.

artículo científico publicado en 2010

Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D.

artículo científico publicado en 2002

The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients

artículo científico publicado en 2006

The union of vascular and metabolic actions of insulin in sickness and in health

artículo científico publicado en 2005

Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin

artículo científico publicado en 2013

Transfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture

artículo científico publicado en 1993

Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance

artículo científico publicado en 2006

Two mutant alleles of the insulin receptor gene in a family with a genetic form of insulin resistance: a 10 base pair deletion in exon 1 and a mutation substituting serine for asparagine-462.

artículo científico publicado en 1995

Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells

artículo científico publicado en 2001

Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes

artículo científico publicado en 2005

Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.

artículo científico publicado en 2007

Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus.

artículo científico publicado en 2007

Lista de obras de Michael J. Quon

A Method of Delivering Dialysate of Constantly Decreasing Osmolality During Dialysis ⬇️

A mathematical model and computer simulation study of insulin receptor regulation

A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.

A phosphotyrosyl mimetic peptide reverses impairment of insulin-stimulated translocation of GLUT4 caused by overexpression of PTP1B in rat adipose cells

ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development

Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle

Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients

Additive beneficial effects of atorvastatin combined with amlodipine in patients with mild-to-moderate hypertension

Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia

Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients

Adiponectin and cardiovascular disease: response to therapeutic interventions.

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

Amyloid beta oligomers induce impairment of neuronal insulin receptors

Anti-inflammatory and metabolic effects of candesartan in hypertensive patients.

Are statins effective for simultaneously treating dyslipidemias and hypertension?

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases

Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model

Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia

Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators.

C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.

Caveats to aggressive lowering of lipids by specific statins.

Cellular Stress, Excessive Apoptosis, and the Effect of Metformin in a Mouse Model of Type 2 Diabetic Embryopathy

Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells.

Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.

Combined therapy with ramipril and simvastatin has beneficial additive effects on tissue factor activity and prothrombin fragment 1+2 in patients with type 2 diabetes

Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice

Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats.

Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium.

Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy

Differential metabolic effects of distinct statins.

Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients.

Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients.

Distinct mechanisms for globular adiponectin that integrate vascular and metabolic actions of insulin to help maintain coordinated cardiovascular and glucose homeostasis.

Dominant negative FADD dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy.

Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin

EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR.

Effects of fenofibrate therapy on circulating adipocytokines in patients with primary hypertriglyceridemia

Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells

Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells ⬇️

Effects of simvastatin therapy on circulating adipocytokines in patients with hypercholesterolemia

Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertension

Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn.

Escherichia coli K1 internalization via caveolae requires caveolin-1 and protein kinase Calpha interaction in human brain microvascular endothelial cells

Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+.

Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.

Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes.

Extracellular conversion of adiponectin hexamers into trimers

FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity.

G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis

Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells

Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.

Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases

High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance

Impaired insulin secretion in the Turner metabolic syndrome

Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes.

Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells

Insulin action and insulin resistance in vascular endothelium.

Insulin and the insulin receptor in experimental models of learning and memory.

Insulin receptor binding kinetics: modeling and simulation studies

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

Insulin receptor substrate-2 (IRS-2) can mediate the action of insulin to stimulate translocation of GLUT4 to the cell surface in rat adipose cells.

Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production.

Insulin signal transduction pathways

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

Leptin and cardiovascular disease: response to therapeutic interventions

Letter by Koh and Quon regarding article, "Evidence mandating earlier and more aggressive treatment of hypercholesterolemia".

Letter re: Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation

Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity

MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness.

Man shall not live by bread alone.

Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complications

Modulation of adiponectin as a potential therapeutic strategy

Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop

Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10.

New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate