Lista de obras - Lucy Walker - Dominio Público Uruguay

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

artículo científico publicado en 2009

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

artículo científico publicado en 2015

Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice.

artículo científico publicado en 2011

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3

artículo científico publicado en 2008

Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95

artículo científico publicado en 1998

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

artículo científico publicado en 2014

B cell depletion in autoimmune diabetes: insights from murine models.

scientific article published on 03 March 2011

B1 cells promote pancreas infiltration by autoreactive T cells.

artículo científico publicado en 2010

CD28 costimulation: Walking the immunological tightrope ⬇️

artículo científico publicado el 1 de enero de 2013

CD4 + CD25 + Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion

scientific article published on 01 September 2004

CD4 T cell differentiation in type 1 diabetes.

artículo científico

CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells

artículo científico publicado en 2003

CD4+ CD25+ Treg: divide and rule?

artículo científico publicado en 2004

CTLA-4 and Autoimmunity: New Twists in the Tale

artículo científico publicado en 2015

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement

artículo científico publicado en 2014

CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen

artículo científico publicado en 2002

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

artículo científico publicado en 2019

CTLA4 gene polymorphism and autoimmunity

artículo científico publicado en 2005

Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

artículo científico publicado en 1999

Confusing signals: recent progress in CTLA-4 biology

artículo científico

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

artículo científico publicado en 2009

Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells

artículo científico publicado en 2006

Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

artículo científico publicado en 2010

Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis

artículo científico publicado en 1998

Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10

artículo científico publicado en 2006

Established T cell-driven germinal center B cell proliferation is independent of CD28 signaling but is tightly regulated through CTLA-4.

artículo científico publicado en 2003

Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

artículo científico publicado en 2020

Follicular helper T cell signature in type 1 diabetes

artículo científico publicado en 2014

Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen

scientific article published on 03 October 2006

Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen

artículo científico publicado en 2002

Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs

artículo científico publicado en 2014

Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease

artículo científico publicado en 2015

IL-2-independent activation and proliferation in human T cells induced by CD28.

artículo científico publicado en 1999

IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis.

artículo científico publicado en 2012

IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

artículo científico publicado en 2014

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.

artículo científico publicado en 2012

Immune regulation and colitis: suppression of acute inflammation allows the development of chronic inflammatory bowel disease

artículo científico publicado en 2005

Immune regulation by CTLA-4--relevance to autoimmune diabetes in a transgenic mouse model

artículo científico publicado en 2011

Lack of activation induced cell death in human T blasts despite CD95L up-regulation: protection from apoptosis by MEK signalling

artículo científico publicado en 1999

MAIT cells in type 1 diabetes: a good friend turned bad.

artículo científico publicado en 2017

Maintaining a Competitive Edge: New Rules for Peripheral T Cell Homeostasis

artículo científico publicado en 2012

Natural Treg in autoimmune diabetes: all present and correct?

artículo científico publicado en 2008

PD-1 and CTLA4: Two checkpoints, one pathway?

artículo científico publicado en 2017

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells.

artículo científico publicado en 2018

Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80

artículo científico publicado en 1998

Publisher Correction: Targeting co-stimulatory molecules in autoimmune disease

artículo científico publicado en 2020

Regulatory T Cells in Autoimmune Diabetes: Mechanisms of Action and Translational Potential.

artículo científico publicado en 2015

Regulatory T cells overturned: the effectors fight back

artículo científico publicado en 2009

Regulatory T cells: Folate receptor 4: a new handle on regulation and memory?

artículo científico publicado en 2007

Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.

artículo científico publicado en 2008

Targeting co-stimulatory molecules in autoimmune disease

scientific article published on 16 September 2020

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses ⬇️

artículo científico publicado el 25 de noviembre de 2011

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

artículo científico publicado en 2006

Treg and CTLA-4: Two intertwining pathways to immune tolerance ⬇️

artículo científico publicado el 10 de julio de 2013

Lista de obras de Lucy Walker

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice.

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3

Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

B cell depletion in autoimmune diabetes: insights from murine models.

B1 cells promote pancreas infiltration by autoreactive T cells.

CD28 costimulation: Walking the immunological tightrope ⬇️

CD4 + CD25 + Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion

CD4 T cell differentiation in type 1 diabetes.

CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells

CD4+ CD25+ Treg: divide and rule?

CTLA-4 and Autoimmunity: New Twists in the Tale

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement

CTLA-4 differentially regulates T cell responses to endogenous tissue protein versus exogenous immunogen

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

CTLA4 gene polymorphism and autoimmunity

Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

Confusing signals: recent progress in CTLA-4 biology

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells

Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis

Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10

Established T cell-driven germinal center B cell proliferation is independent of CD28 signaling but is tightly regulated through CTLA-4.

Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

Follicular helper T cell signature in type 1 diabetes

Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen

Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen

Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs

Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease

IL-2-independent activation and proliferation in human T cells induced by CD28.

IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis.

IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.

Immune regulation and colitis: suppression of acute inflammation allows the development of chronic inflammatory bowel disease

Immune regulation by CTLA-4--relevance to autoimmune diabetes in a transgenic mouse model

Lack of activation induced cell death in human T blasts despite CD95L up-regulation: protection from apoptosis by MEK signalling

MAIT cells in type 1 diabetes: a good friend turned bad.

Maintaining a Competitive Edge: New Rules for Peripheral T Cell Homeostasis

Natural Treg in autoimmune diabetes: all present and correct?

PD-1 and CTLA4: Two checkpoints, one pathway?

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells.

Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80

Publisher Correction: Targeting co-stimulatory molecules in autoimmune disease

Regulatory T Cells in Autoimmune Diabetes: Mechanisms of Action and Translational Potential.

Regulatory T cells overturned: the effectors fight back

Regulatory T cells: Folate receptor 4: a new handle on regulation and memory?

Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.

Targeting co-stimulatory molecules in autoimmune disease

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses ⬇️

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

Treg and CTLA-4: Two intertwining pathways to immune tolerance ⬇️