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Lista de obras de Jaroslav Malina

A DNA-binding copper(I) metallosupramolecular cylinder that acts as an artificial nuclease.

artículo científico publicado en 2006

Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(III) in cell-free media

artículo científico publicado en 2001

Chiral discrimination in platinum anticancer drugs.

artículo científico publicado en 2002

Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.

artículo científico publicado en 2007

DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins.

artículo científico publicado en 2005

DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference

artículo científico publicado en 2008

DNA condensing effects and sequence selectivity of DNA binding of antitumor noncovalent polynuclear platinum complexes.

artículo científico publicado en 2014

DNA interactions of 2-pyrrolinodoxorubicin, a distinctively more potent daunosamine-modified analogue of doxorubicin

artículo científico publicado en 2011

DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.

artículo científico publicado en 2000

DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: thermodynamic analysis and chemical probing.

artículo científico publicado en 2011

DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes

artículo científico publicado el 15 de noviembre de 2003

Design and DNA binding of an extended triple-stranded metallo-supramolecular cylinder.

artículo científico publicado en 2005

Design, Preparation, and Characterization of Zn and Cu Metallopeptides Based On Tetradentate Aminopyridine Ligands Showing Enhanced DNA Cleavage Activity.

artículo científico publicado en 2015

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex

artículo científico publicado en 2012

Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenes

artículo científico publicado en 2010

Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light

artículo científico publicado en 2015

Influence of surface shape on DNA binding of bimetallo helicates.

artículo científico publicado en 2007

Interaction of dinuclear ruthenium(II) supramolecular cylinders with DNA: sequence-specific binding, unwinding, and photocleavage.

artículo científico publicado en 2008

Iron(II) supramolecular helicates condense plasmid DNA and inhibit vital DNA-related enzymatic activities

artículo científico publicado en 2015

Iron(II) supramolecular helicates interfere with the HIV-1 Tat-TAR RNA interaction critical for viral replication.

artículo científico publicado en 2016

Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes

artículo científico publicado en 2009

Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways

artículo científico publicado en 2019

Metallohelices with activity against cisplatin-resistant cancer cells; does the mechanism involve DNA binding?

article by Viktor Brabec et al published 2013 in Chemical Science

Multiply Intercalator-Substituted Cu(II) Cyclen Complexes as DNA Condensers and DNA/RNA Synthesis Inhibitors.

artículo científico publicado en 2018

NMR analysis of duplex d(CGCGATCGCG)2 modified by Lambda- and Delta-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study

artículo científico publicado en 2006

NMR analysis of duplex d(CGCGATCGCG)2 modified by Λ- and Δ-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study.

artículo científico publicado en 2007

Optically Pure Metallohelices That Accumulate in Cell Nuclei, Condense/Aggregate DNA, and Inhibit Activities of DNA Processing Enzymes

scientific article published on 17 February 2020

Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity

artículo científico publicado en 2011

Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices.

artículo científico publicado en 2015

Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair

artículo científico publicado en 2011

Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1.

artículo científico publicado en 2015

Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.

artículo científico publicado en 2013

Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.

artículo científico publicado en 2009

Substitution-Inert Polynuclear Platinum Complexes Act as Potent Inducers of Condensation/Aggregation of Short Single- and Double-Stranded DNA and RNA Oligonucleotides

artículo científico publicado en 2019

Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates

artículo científico publicado en 2020

Substitution-Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex-Forming Templates

scientific article published on 07 June 2018

Substitution-inert trinuclear platinum complexes efficiently condense/aggregate nucleic acids and inhibit enzymatic activity

artículo científico publicado en 2014

The thermodynamics of translesion DNA synthesis past major adducts of enantiomeric analogues of antitumor cisplatin

artículo científico publicado en 2012

Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug.

artículo científico publicado en 2012

Thermodynamic impact of abasic sites on simulated translesion DNA synthesis

artículo científico publicado en 2014

Thermodynamic properties of damaged DNA and its recognition by xeroderma pigmentosum group A protein and replication protein A.

artículo científico publicado en 2005

Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents.

artículo científico publicado en 2004

Tröger's base scaffold in racemic and chiral fashion as a spacer for bisdistamycin formation. Synthesis and DNA binding study

Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.

artículo científico publicado en 2010