Lista de obras - Daniela Fattori - Dominio Público Uruguay

4-N-Hydroxy-4-[1-(sulfonyl)piperidin-4-yl]-butyramides as HDAC inhibitors.

artículo científico publicado en 2011

A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand

artículo científico publicado en 2005

A new method for chemoselective conjugation of unprotected peptides to dauno- and doxorubicin.

artículo científico publicado en 2001

A practical approach to the synthesis of hairpin polyamide–peptide conjugates through the use of a safety-catch linker

artículo científico publicado en 2002

A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies

artículo científico publicado en 2006

Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors.

artículo científico publicado en 2011

Alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease

artículo científico publicado en 2000

Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 1: hit identification

artículo científico publicado en 2013

Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 2: 7-fluorobenzothiophenes and benzofurans.

artículo científico publicado en 2015

Bradykinin receptor antagonists--a review of the patent literature 2005-2008.

scientific article published on July 2009

Cinnamic acids and mono-substituted benzoic acids as useful capping groups for the preparation of hNK2 receptor antagonists

artículo científico publicado en 2008

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides

artículo científico publicado en 2006

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 2. Synthesis and structure-activity relationships of alpha,alpha-cycloalkylglycine sulfonamides.

artículo científico publicado en 2007

Fragment-Based Ligand Discovery

Fragment-based approach to drug lead discovery: overview and advances in various techniques

artículo científico publicado en 2008

Highly stereoselective, total synthesis of β-c-hexopyranosyl derivatives

Histone deacetylase inhibitors: from bench to clinic

scientific article published on 05 February 2008

Molecular recognition: the fragment approach in lead generation.

artículo científico publicado en 2004

Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus

artículo científico publicado en 2002

Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer

artículo científico publicado en 2000

Set-up of a new series of HDAC inhibitors: the 5,11-dihydrodibenzo[b,e]azepin-6-ones as privileged structures.

artículo científico publicado en 2012

Small molecule antagonists of the tachykinin NK 2 receptor.

artículo científico publicado en 2004

Solid-phase synthesis of unsymmetrical ureas through the use of Kenner safety-catch linker

Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor

artículo científico publicado en 2010

Synthesis of a functionalized high affinity mannose receptor ligand and its application in the construction of peptide-, polyamide- and PNA-conjugates.

artículo científico publicado en 2003

The Demjanov and Tiffeneau-Demjanov one-carbon ring enlargements of 2-aminomethyl-7-oxabicyclo[2.2.1]heptane derivatives. The stereo- and regioselective additions of 8-oxabicyclo[3.2.1]oct-6-en-2-one to soft electrophiles

article

The Syntheses of 3- and 4-Deoxy-hexoses

The electron-releasing homoconjugated carbonyl group. Application to the total syntheses of 3-deoxy-, 4-deoxy-hexose, lividosamine and derivatives

Total asymmetric syntheses of 3- and 4-deoxy-hexoses and derivatives

Total asymmetric syntheses of d-lividosamine and 2-acetamido-2,3-dideoxy-d-arabino-hexose derivatives

alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists

artículo científico publicado en 2007

alpha,alpha-Cyclopentaneglycine dipeptides capped with biaryls as tachykinin NK(2) receptor antagonists.

artículo científico publicado en 2008

hNK2 receptor antagonists. The use of intramolecular hydrogen bonding to increase solubility and membrane permeability

artículo científico publicado en 2011

Lista de obras de Daniela Fattori

4-N-Hydroxy-4-[1-(sulfonyl)piperidin-4-yl]-butyramides as HDAC inhibitors.

A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand

A new method for chemoselective conjugation of unprotected peptides to dauno- and doxorubicin.

A practical approach to the synthesis of hairpin polyamide–peptide conjugates through the use of a safety-catch linker

A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies

Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors.

Alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease

Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 1: hit identification

Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 2: 7-fluorobenzothiophenes and benzofurans.

Bradykinin receptor antagonists--a review of the patent literature 2005-2008.

Cinnamic acids and mono-substituted benzoic acids as useful capping groups for the preparation of hNK2 receptor antagonists

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 2. Synthesis and structure-activity relationships of alpha,alpha-cycloalkylglycine sulfonamides.

Fragment-Based Ligand Discovery

Fragment-based approach to drug lead discovery: overview and advances in various techniques

Highly stereoselective, total synthesis of β-c-hexopyranosyl derivatives

Histone deacetylase inhibitors: from bench to clinic

Molecular recognition: the fragment approach in lead generation.

Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus

Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer

Set-up of a new series of HDAC inhibitors: the 5,11-dihydrodibenzo[b,e]azepin-6-ones as privileged structures.

Small molecule antagonists of the tachykinin NK 2 receptor.

Solid-phase synthesis of unsymmetrical ureas through the use of Kenner safety-catch linker

Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor

Synthesis of a functionalized high affinity mannose receptor ligand and its application in the construction of peptide-, polyamide- and PNA-conjugates.

The Demjanov and Tiffeneau-Demjanov one-carbon ring enlargements of 2-aminomethyl-7-oxabicyclo[2.2.1]heptane derivatives. The stereo- and regioselective additions of 8-oxabicyclo[3.2.1]oct-6-en-2-one to soft electrophiles

The Syntheses of 3- and 4-Deoxy-hexoses

The electron-releasing homoconjugated carbonyl group. Application to the total syntheses of 3-deoxy-, 4-deoxy-hexose, lividosamine and derivatives

Total asymmetric syntheses of 3- and 4-deoxy-hexoses and derivatives

Total asymmetric syntheses of d-lividosamine and 2-acetamido-2,3-dideoxy-d-arabino-hexose derivatives

alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists

alpha,alpha-Cyclopentaneglycine dipeptides capped with biaryls as tachykinin NK(2) receptor antagonists.

hNK2 receptor antagonists. The use of intramolecular hydrogen bonding to increase solubility and membrane permeability