Lista de obras - Johannes Grillari - Dominio Público Uruguay

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

artículo científico publicado en 2010

A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells

artículo científico publicado en 2012

A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines

artículo científico publicado en 2016

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

artículo científico publicado en 2012

Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.

artículo científico publicado en 2017

Age-related alterations in the protein expression profile of C57BL/6J mouse pituitaries.

artículo científico publicado en 2002

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

artículo científico publicado en 2009

Analysis of alterations in gene expression after amplification of recombinant genes in CHO cells

artículo científico publicado en 2001

Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

artículo científico publicado en 2014

Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data

artículo científico publicado en 2015

Antimicrobial photodynamic therapy fighting polymicrobial infections - a journey from in vitro to in vivo

artículo científico publicado en 2020

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo.

artículo científico publicado en 2016

Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators

artículo científico publicado en 2016

Biogerontology in Austria

artículo científico publicado en 2010

Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.

artículo científico publicado en 2009

CHO microRNA engineering is growing up: recent successes and future challenges

artículo científico publicado en 2013

Characterization of a novel cell penetrating peptide derived from human Oct4.

artículo científico publicado en 2014

Chinese hamster genome sequenced from sorted chromosomes

artículo científico publicado en 2013

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

artículo científico publicado en 2016

Circulating microRNA Signatures in Patients With Idiopathic and Postmenopausal Osteoporosis and Fragility Fractures.

artículo científico publicado en 2016

Circulating microRNAs as novel biomarkers for bone diseases - Complex signatures for multifactorial diseases?

artículo científico publicado en 2015

Circulating microRNAs in young individuals with long-duration type 1 diabetes in comparison with healthy controls

artículo científico publicado en 2023

Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

artículo científico publicado en 2012

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

artículo científico publicado en 2012

Contributions of DNA interstrand cross-links to aging of cells and organisms

artículo científico publicado en 2007

Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

artículo científico publicado en 2016

Cost-utility analysis of fracture risk assessment using microRNAs compared with standard tools and no monitoring in the Austrian female population

artículo científico publicado en 2017

Critical Impact of Human Amniotic Membrane Tension on Mitochondrial Function and Cell Viability In Vitro

scientific article published on 15 December 2019

Delineation of the key aspects in the regulation of epithelial monolayer formation

artículo científico publicado en 2013

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.

artículo científico publicado en 2015

Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures

artículo científico publicado en 2011

Early embryonic lethality of mice lacking the essential protein SNEV

artículo científico publicado en 2007

Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells

artículo científico publicado en 2014

Endothelial Cell-derived Extracellular Vesicles Size-dependently Exert Procoagulant Activity Detected by Thromboelastometry

artículo científico publicado en 2017

Endothelial Extracellular Vesicles-Promises and Challenges

artículo científico publicado en 2017

Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway

artículo científico publicado en 2015

Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.

artículo científico publicado en 2011

Erratum: Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles

artículo científico publicado en 2016

Establishment of a strategy for the rapid generation of a monoclonal antibody against the human protein SNEV (hNMP200) by flow-cytometric cell sorting

artículo científico publicado en 2005

Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing

artículo científico publicado en 2011

Fluorescence-Based Nanoparticle Tracking Analysis and Flow Cytometry for Characterization of Endothelial Extracellular Vesicle Release

scientific article published on 04 December 2020

From cellular senescence to age-associated diseases: the miRNA connection

artículo científico publicado en 2012

Generation of human induced pluripotent stem cells from urine samples.

artículo científico publicado en 2012

Generation of induced pluripotent stem cells from urine

artículo científico publicado en 2011

GiSAO.db: a database for ageing research

artículo científico publicado en 2011

Grundlagen der biologischen Alterung

artículo científico publicado en 2015

HIV-1 induces telomerase activity in monocyte-derived macrophages, possibly safeguarding one of its reservoirs.

artículo científico publicado en 2012

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

artículo científico publicado en 2008

High-glucose--triggered apoptosis in cultured endothelial cells

artículo científico publicado en 1995

Human cell lines for the production of recombinant proteins: on the horizon.

artículo científico

Identification of cultivation-independent markers of human endothelial cell senescence in vitro

artículo científico publicado en 2007

Identification of evolutionarily conserved genetic regulators of cellular aging

artículo científico publicado en 2010

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts

artículo científico publicado en 2013

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

artículo científico publicado en 2014

In Search of 'Omics'-Based Biomarkers to Predict Risk of Frailty and Its Consequences in Older Individuals: The FRAILOMIC Initiative.

artículo científico publicado en 2015

Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA

artículo científico publicado en 2012

Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome

artículo científico publicado en 2005

Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target

artículo científico publicado en 2022

Investigations into cytotoxic effects of the herbal preparation Abnormal Savda Munziq

artículo científico publicado en 2015

Killer T cells: a promising new tool for adoptive immunotherapy

artículo científico publicado en 2002

Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

artículo científico publicado en 2016

Laboratory biomarkers and frailty: presentation of the FRAILOMIC initiative

artículo científico publicado en 2015

Large-scale production and characterization of novel CD4+ cytotoxic T cells with broad tumor specificity for immunotherapy

artículo científico publicado en 2009

Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.

artículo científico publicado en 2017

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

artículo científico publicado en 2015

MicroRNA-17-5p: At the Crossroads of Cancer and Aging - A Mini-Review

artículo científico publicado en 2016

MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes

scientific article published on 01 June 2014

MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor

artículo científico publicado en 2014

MicroRNAs and toxicology: A love marriage

artículo científico publicado en 2017

MicroRNAs differentially present in the plasma of HIV elite controllers reduce HIV infection in vitro

artículo científico publicado en 2014

Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity

artículo científico publicado en 2015

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells

artículo científico publicado en 2014

Next-generation sequencing of the CHO cell transcriptome

artículo científico publicado en 2011

Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

artículo científico publicado en 2011

Novel human renal proximal tubular cell line for the production of complex proteins.

artículo científico publicado en 2014

OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes.

artículo científico publicado en 2017

OncomiR-17-5p: alarm signal in cancer?

artículo científico publicado en 2017

Oncostatin M is a novel inhibitor of TGF-β1-induced matricellular protein expression.

artículo científico publicado en 2011

Optimization of a quantitative PCR based method for plasmid copy number determination in human cell lines.

artículo científico publicado en 2015

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

artículo científico publicado en 2020

Post-translational modification of cellular proteins by ubiquitin and ubiquitin-like molecules: role in cellular senescence and aging.

scientific article published on January 2010

Prediction of transcribed PIWI-interacting RNAs from CHO RNAseq data

artículo científico publicado en 2013

Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis

artículo científico publicado en 2017

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

artículo científico publicado en 2005

SNEV overexpression extends the life span of human endothelial cells

artículo científico publicado en 2006

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

artículo científico publicado en 2015

SNEVhPrp19/hPso4 Regulates Adipogenesis of Human Adipose Stromal Cells

artículo científico publicado en 2016

Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells.

artículo científico publicado en 2016

Secretion of microvesicular miRNAs in cellular and organismal aging.

artículo científico

Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro.

artículo científico publicado en 2016

Stable overexpression of miR-17 enhances recombinant protein production of CHO cells

artículo científico publicado en 2014

Subtractive hybridization of mRNA from early passage and senescent endothelial cells

artículo científico publicado en 2000

The CHO miRNA Transcriptome

The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy.

artículo científico publicado en 2017

The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone.

artículo científico publicado en 2014

Transcriptomic changes in CHO cells after adaptation to suspension growth in protein-free medium analysed by a species-specific microarray

artículo científico

UVB-Induced Senescence of Human Dermal Fibroblasts Involves Impairment of Proteasome and Enhanced Autophagic Activity.

artículo científico publicado en 2016

Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

artículo científico publicado en 2017

Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing

artículo científico publicado en 2011

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death

artículo científico publicado en 2012

Urine as a source of stem cells.

artículo científico publicado en 2013

Urine is a novel source of autologous mesenchymal stem cells for patients with epidermolysis bullosa.

artículo científico publicado en 2015

Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics

artículo científico publicado en 2012

Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles

artículo científico publicado en 2016

WNT signaling suppression in the senescent human thymus.

artículo científico publicado en 2014

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

artículo científico publicado en 2010

miR-17-92 cluster: ups and downs in cancer and aging

artículo científico publicado en 2010

miRNA-21 deficiency impairs alveolar socket healing in mice

artículo científico publicado en 2020

miRNAs – pathway engineering of CHO cell factories that avoids translational burdening ⬇️

artículo científico publicado el 4 de junio de 2012

Lista de obras de Johannes Grillari

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells

A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.

Age-related alterations in the protein expression profile of C57BL/6J mouse pituitaries.

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

Analysis of alterations in gene expression after amplification of recombinant genes in CHO cells

Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data

Antimicrobial photodynamic therapy fighting polymicrobial infections - a journey from in vitro to in vivo

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo.

Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators

Biogerontology in Austria

Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.

CHO microRNA engineering is growing up: recent successes and future challenges

Characterization of a novel cell penetrating peptide derived from human Oct4.

Chinese hamster genome sequenced from sorted chromosomes

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

Circulating microRNA Signatures in Patients With Idiopathic and Postmenopausal Osteoporosis and Fragility Fractures.

Circulating microRNAs as novel biomarkers for bone diseases - Complex signatures for multifactorial diseases?

Circulating microRNAs in young individuals with long-duration type 1 diabetes in comparison with healthy controls

Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

Contributions of DNA interstrand cross-links to aging of cells and organisms

Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

Cost-utility analysis of fracture risk assessment using microRNAs compared with standard tools and no monitoring in the Austrian female population

Critical Impact of Human Amniotic Membrane Tension on Mitochondrial Function and Cell Viability In Vitro

Delineation of the key aspects in the regulation of epithelial monolayer formation

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.

Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures

Early embryonic lethality of mice lacking the essential protein SNEV

Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells

Endothelial Cell-derived Extracellular Vesicles Size-dependently Exert Procoagulant Activity Detected by Thromboelastometry

Endothelial Extracellular Vesicles-Promises and Challenges

Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway

Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.

Erratum: Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles

Establishment of a strategy for the rapid generation of a monoclonal antibody against the human protein SNEV (hNMP200) by flow-cytometric cell sorting

Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing

Fluorescence-Based Nanoparticle Tracking Analysis and Flow Cytometry for Characterization of Endothelial Extracellular Vesicle Release

From cellular senescence to age-associated diseases: the miRNA connection

Generation of human induced pluripotent stem cells from urine samples.

Generation of induced pluripotent stem cells from urine

GiSAO.db: a database for ageing research

Grundlagen der biologischen Alterung

HIV-1 induces telomerase activity in monocyte-derived macrophages, possibly safeguarding one of its reservoirs.

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

High-glucose--triggered apoptosis in cultured endothelial cells

Human cell lines for the production of recombinant proteins: on the horizon.

Identification of cultivation-independent markers of human endothelial cell senescence in vitro

Identification of evolutionarily conserved genetic regulators of cellular aging

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

In Search of 'Omics'-Based Biomarkers to Predict Risk of Frailty and Its Consequences in Older Individuals: The FRAILOMIC Initiative.

Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA

Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome

Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target

Investigations into cytotoxic effects of the herbal preparation Abnormal Savda Munziq

Killer T cells: a promising new tool for adoptive immunotherapy

Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

Laboratory biomarkers and frailty: presentation of the FRAILOMIC initiative

Large-scale production and characterization of novel CD4+ cytotoxic T cells with broad tumor specificity for immunotherapy

Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

MicroRNA-17-5p: At the Crossroads of Cancer and Aging - A Mini-Review

MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes

MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor

MicroRNAs and toxicology: A love marriage

MicroRNAs differentially present in the plasma of HIV elite controllers reduce HIV infection in vitro

Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells

Next-generation sequencing of the CHO cell transcriptome

Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

Novel human renal proximal tubular cell line for the production of complex proteins.

OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes.

OncomiR-17-5p: alarm signal in cancer?

Oncostatin M is a novel inhibitor of TGF-β1-induced matricellular protein expression.

Optimization of a quantitative PCR based method for plasmid copy number determination in human cell lines.