Lista de obras - Axel Bidon-Chanal - Dominio Público Uruguay

A new quinoxaline-containing peptide induces apoptosis in cancer cells by autophagy modulation

artículo científico publicado en 2015

An 'open' structure of the RecOR complex supports ssDNA binding within the core of the complex

artículo científico publicado en 2013

Chemical Reactivity in the Ground and the Excited State

Comparative analysis of inner cavities and ligand migration in non-symbiotic AHb1 and AHb2.

artículo científico publicado en 2013

Continuum solvation models: Dissecting the free energy of solvation

Derivation of Distributed Models of Atomic Polarizability for Molecular Simulations

artículo científico publicado en 2007

Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease

artículo científico publicado en 2005

Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.

artículo científico publicado en 2005

Dynamical regulation of ligand migration by a gate-opening molecular switch in truncated hemoglobin-N from Mycobacterium tuberculosis.

artículo científico publicado en 2007

Essential Dynamics: A Tool for Efficient Trajectory Compression and Management

artículo científico publicado en 2006

Evidence for a new binding mode to GSK-3: allosteric regulation by the marine compound palinurin.

artículo científico publicado en 2012

High pressure reveals structural determinants for globin hexacoordination: Neuroglobin and myoglobin cases

artículo científico publicado en 2009

Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 fromArabidopsis thaliana

artículo científico publicado en 2011

Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases

artículo científico publicado en 2012

Identification and Characterization of a Secondary Sodium-Binding Site and the Main Selectivity Determinants in the Human Concentrative Nucleoside Transporter 3.

artículo científico publicado en 2017

Impaired Transport of Nucleotides in a Mitochondrial Carrier Explains Severe Human Genetic Diseases

artículo científico publicado en 2012

Kinetics and computational studies of ligand migration in nitrophorin 7 and its Δ1-3 mutant.

artículo científico publicado en 2013

Ligand migration through hemeprotein cavities: insights from laser flash photolysis and molecular dynamics simulations.

artículo científico publicado en 2013

Ligand-induced dynamical regulation of NO conversion in Mycobacterium tuberculosis truncated hemoglobin-N

artículo científico publicado en 2006

MDpocket: open-source cavity detection and characterization on molecular dynamics trajectories

artículo científico publicado en 2011

MST Continuum Study of the Hydration Free Energies of Monovalent Ionic Species

artículo científico publicado en 2005

MST study of group contributions for alkane derivatives: effect of the charge normalization

artículo científico publicado en 2004

Mechanism of Product Release in NO Detoxification from Mycobacterium tuberculosis Truncated Hemoglobin N

artículo científico publicado en 2008

Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: role of the CD loop and pre-A motif in electron cycling

artículo científico publicado en 2014

Modulating Ligand Dissociation through Methyl Isomerism in Accessory Sites: Binding of Retinol to Cellular Carriers

scientific article published on 14 November 2019

Molecular modeling of class I and II alleles of the major histocompatibility complex in Salmo salar

artículo científico publicado en 2010

Nitric oxide reactivity with globins as investigated through computer simulation.

artículo científico publicado en 2008

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

artículo científico publicado en 2015

Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

artículo científico publicado en 2008

Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates

artículo científico publicado en 2010

Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport

article

Role of PheE15 gate in ligand entry and nitric oxide detoxification function of mycobacterium tuberculosis truncated hemoglobin N.

artículo científico publicado en 2012

Role of Pre-A motif in nitric oxide scavenging by truncated hemoglobin, HbN, of Mycobacterium tuberculosis.

artículo científico publicado en 2009

Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors

artículo científico publicado en 2015

Structural Plasticity in Globins: Role of Protein Dynamics in Defining Ligand Migration Pathways.

artículo científico publicado en 2016

Structural determinants of the multifunctional profile of dual binding site acetylcholinesterase inhibitors as anti-Alzheimer agents.

artículo científico publicado en 2010

Structural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.

artículo científico publicado en 2009

Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.

artículo científico publicado en 2015

Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates.

artículo científico publicado en 2010

The N-terminal pre-A region of Mycobacterium tuberculosis 2/2HbN promotes NO-dioxygenase activity

artículo científico publicado en 2016

Lista de obras de Axel Bidon-Chanal

A new quinoxaline-containing peptide induces apoptosis in cancer cells by autophagy modulation

An 'open' structure of the RecOR complex supports ssDNA binding within the core of the complex

Chemical Reactivity in the Ground and the Excited State

Comparative analysis of inner cavities and ligand migration in non-symbiotic AHb1 and AHb2.

Continuum solvation models: Dissecting the free energy of solvation

Derivation of Distributed Models of Atomic Polarizability for Molecular Simulations

Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease

Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.

Dynamical regulation of ligand migration by a gate-opening molecular switch in truncated hemoglobin-N from Mycobacterium tuberculosis.

Essential Dynamics: A Tool for Efficient Trajectory Compression and Management

Evidence for a new binding mode to GSK-3: allosteric regulation by the marine compound palinurin.

High pressure reveals structural determinants for globin hexacoordination: Neuroglobin and myoglobin cases

Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 fromArabidopsis thaliana

Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases

Identification and Characterization of a Secondary Sodium-Binding Site and the Main Selectivity Determinants in the Human Concentrative Nucleoside Transporter 3.

Impaired Transport of Nucleotides in a Mitochondrial Carrier Explains Severe Human Genetic Diseases

Kinetics and computational studies of ligand migration in nitrophorin 7 and its Δ1-3 mutant.

Ligand migration through hemeprotein cavities: insights from laser flash photolysis and molecular dynamics simulations.

Ligand-induced dynamical regulation of NO conversion in Mycobacterium tuberculosis truncated hemoglobin-N

MDpocket: open-source cavity detection and characterization on molecular dynamics trajectories

MST Continuum Study of the Hydration Free Energies of Monovalent Ionic Species

MST study of group contributions for alkane derivatives: effect of the charge normalization

Mechanism of Product Release in NO Detoxification from Mycobacterium tuberculosis Truncated Hemoglobin N

Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: role of the CD loop and pre-A motif in electron cycling

Modulating Ligand Dissociation through Methyl Isomerism in Accessory Sites: Binding of Retinol to Cellular Carriers

Molecular modeling of class I and II alleles of the major histocompatibility complex in Salmo salar

Nitric oxide reactivity with globins as investigated through computer simulation.

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates

Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport

Role of PheE15 gate in ligand entry and nitric oxide detoxification function of mycobacterium tuberculosis truncated hemoglobin N.

Role of Pre-A motif in nitric oxide scavenging by truncated hemoglobin, HbN, of Mycobacterium tuberculosis.

Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors

Structural Plasticity in Globins: Role of Protein Dynamics in Defining Ligand Migration Pathways.

Structural determinants of the multifunctional profile of dual binding site acetylcholinesterase inhibitors as anti-Alzheimer agents.

Structural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.

Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.

Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates.

The N-terminal pre-A region of Mycobacterium tuberculosis 2/2HbN promotes NO-dioxygenase activity