Lista de obras - Maarten Altelaar - Dominio Público Uruguay

A CDK-mediated phosphorylation switch of disordered protein condensation

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

scientific article published on 29 January 2020

Assessment of SRM, MRM(3) , and DIA for the targeted analysis of phosphorylation dynamics in non-small cell lung cancer.

artículo científico publicado en 2016

Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis

artículo científico publicado en 2016

Automated High-Throughput Method for the Fast, Robust, and Reproducible Enrichment of Newly Synthesized Proteins

artículo científico publicado en 2021

Automated, feature-based image alignment for high-resolution imaging mass spectrometry of large biological samples.

artículo científico publicado en 2008

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts

artículo científico publicado en 2016

Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization

artículo científico

Benchmarking stable isotope labeling based quantitative proteomics

artículo científico publicado en 2012

CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC

artículo científico publicado en 2024

Cellular imaging using matrix-enhanced and metal-assisted SIMS.

artículo científico publicado en 2010

Characterization of electron transfer dissociation in the Orbitrap Velos HCD cell

artículo científico publicado en 2013

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux

scientific article published on 26 November 2019

Combined Quantitative (Phospho)proteomics and Mass Spectrometry Imaging Reveal Temporal and Spatial Protein Changes in Human Intestinal Ischemia-Reperfusion

artículo científico publicado en 2021

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma

scientific article published on 17 June 2019

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

artículo científico publicado en 2015

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

artículo científico publicado en 2015

Cultivation of Podospora anserina on soybean hulls results in an efficient enzyme cocktail for plant biomass hydrolysis

artículo científico publicado en 2017

Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

artículo científico publicado en 2021

Database independent proteomics analysis of the ostrich and human proteome.

artículo científico publicado en 2011

Deep proteome profiling of Trichoplax adhaerens reveals remarkable features at the origin of metazoan multicellularity.

artículo científico publicado en 2013

Deletion of flbA results in increased secretome complexity and reduced secretion heterogeneity in colonies of Aspergillus niger

artículo científico publicado en 2013

Determination of polycyclic aromatic hydrocarbons and polycylic aromatic sulfur heterocycles by high-performance liquid chromatography with fluorescence and atmospheric pressure chemical ionization mass spectrometry detection in seawater and [...]

artículo científico publicado en 2002

Diet-induced neuropeptide expression: feasibility of quantifying extended and highly charged endogenous peptide sequences by selected reaction monitoring

artículo científico publicado en 2015

Differential proteomics reveals the hallmarks of seed development in common bean (Phaseolus vulgaris L.).

artículo científico publicado en 2016

Dimethyl isotope labeling assisted de novo peptide sequencing ⬇️

artículo científico publicado el 21 de agosto de 2010

Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry.

artículo científico publicado en 2005

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

artículo científico publicado en 2016

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

artículo científico publicado en 2015

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

artículo científico publicado en 2022

Elucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

artículo científico publicado en 2017

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

artículo científico publicado en 2014

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.

artículo científico publicado en 2014

Gaining efficiency by parallel quantification and identification of iTRAQ-labeled peptides using HCD and decision tree guided CID/ETD on an LTQ Orbitrap.

artículo científico publicado en 2010

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

artículo científico publicado en 2017

Identification of a tumor-specific allo-HLA-restricted γδTCR

scientific article published on 01 October 2019

Identification of putative substrates for the periplasmic chaperone YfgM in Escherichia coli using quantitative proteomics

artículo científico publicado en 2014

Imaging of peptides in the rat brain using MALDI-FTICR mass spectrometry.

artículo científico publicado en 2006

Improved identification of endogenous peptides from murine nervous tissue by multiplexed peptide extraction methods and multiplexed mass spectrometric analysis

artículo científico publicado en 2009

Improved peptide identification by targeted fragmentation using CID, HCD and ETD on an LTQ-Orbitrap Velos.

artículo científico publicado en 2011

Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

artículo científico publicado en 2011

In-depth profiling of post-translational modifications on the related transcription factor complexes TFIID and SAGA.

artículo científico publicado en 2009

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell-Specific Proteases

artículo científico publicado en 2016

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

artículo científico publicado en 2017

Monitoring light/dark association dynamics of multi-protein complexes in cyanobacteria using size exclusion chromatography-based proteomics.

artículo científico publicado en 2016

Multistep mechanism of G-quadruplex resolution during DNA replication

artículo científico publicado en 2021

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

artículo científico publicado en 2015

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids ⬇️

artículo científico publicado en 2015

Next-generation proteomics: towards an integrative view of proteome dynamics.

artículo científico publicado en 2012

Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)n and (X)nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics

artículo científico publicado en 2016

PaDuA: A Python Library for High-Throughput (Phospho)proteomics Data Analysis

scientific article published on 21 December 2018

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

artículo científico publicado en 2015

Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence

artículo científico publicado en 2014

Probing the Proteome Response to Toluene Exposure in the Solvent Tolerant Pseudomonas putida S12

article

Profiling of diet-induced neuropeptide changes in rat brain by quantitative mass spectrometry

artículo científico publicado en 2013

Progressive methylation of ageing histones by Dot1 functions as a timer.

artículo científico

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

artículo científico publicado en 2014

Protein signatures associated with tumor cell dissemination in head and neck cancer

artículo científico publicado en 2011

Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2)

artículo científico publicado en 2015

Proteomics and Phosphoproteomics Profiling of Drug-Addicted BRAFi-Resistant Melanoma Cells

artículo científico publicado en 2021

Quantitative Map of Proteome Dynamics during Neuronal Differentiation.

artículo científico publicado en 2017

Quantitative Proteomics Illuminates a Functional Interaction between mDia2 and the Proteasome

artículo científico publicado en 2016

Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway

artículo científico publicado en 2013

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

artículo científico publicado en 2014

Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons.

artículo científico publicado en 2016

Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

artículo científico publicado en 2015

Similar is not the same: differences in the function of the (hemi-)cellulolytic regulator XlnR (Xlr1/Xyr1) in filamentous fungi.

artículo científico publicado en 2014

Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution.

artículo científico publicado en 2014

Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage

artículo científico publicado en 2021

Spatially Resolving the Secretome within the Mycelium of the Cell Factory Aspergillus niger

artículo científico publicado en 2012

Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Display Altered Proteomes at Early Stages of Differentiation

artículo científico publicado en 2021

Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.

artículo científico publicado en 2008

Surface-enhanced resonance Raman spectroscopy as an identification tool in column liquid chromatography.

artículo científico publicado en 2000

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

scientific journal article

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

artículo científico publicado en 2016

Temporal quantitative proteomics of mGluR-induced protein translation and phosphorylation in neurons

scientific article published on 10 September 2020

The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo

artículo científico publicado en 2017

Tissue analysis with high-resolution imaging mass spectrometry.

artículo científico publicado en 2009

Tools and strategies for visualization of large image data sets in high-resolution imaging mass spectrometry.

artículo científico publicado en 2007

Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry.

artículo científico publicado en 2012

Trends in ultrasensitive proteomics ⬇️

artículo científico publicado el 7 de enero de 2012

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

artículo científico publicado en 2020

Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD)

artículo científico publicado en 2013

Uncovering the abilities of Agaricus bisporus to degrade plant biomass throughout its life cycle.

artículo científico publicado en 2015

Unravelling the Neospora caninum secretome through the secreted fraction (ESA) and quantification of the discharged tachyzoite using high-resolution mass spectrometry-based proteomics

artículo científico publicado en 2013

VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function

artículo científico publicado en 2019

Vasohibins encode tubulin detyrosinating activity

artículo científico publicado en 2017

Lista de obras de Maarten Altelaar

A CDK-mediated phosphorylation switch of disordered protein condensation

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

Assessment of SRM, MRM(3) , and DIA for the targeted analysis of phosphorylation dynamics in non-small cell lung cancer.

Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis

Automated High-Throughput Method for the Fast, Robust, and Reproducible Enrichment of Newly Synthesized Proteins

Automated, feature-based image alignment for high-resolution imaging mass spectrometry of large biological samples.

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts

Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization

Benchmarking stable isotope labeling based quantitative proteomics

CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC

Cellular imaging using matrix-enhanced and metal-assisted SIMS.

Characterization of electron transfer dissociation in the Orbitrap Velos HCD cell

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux

Combined Quantitative (Phospho)proteomics and Mass Spectrometry Imaging Reveal Temporal and Spatial Protein Changes in Human Intestinal Ischemia-Reperfusion

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

Cultivation of Podospora anserina on soybean hulls results in an efficient enzyme cocktail for plant biomass hydrolysis

Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

Database independent proteomics analysis of the ostrich and human proteome.

Deep proteome profiling of Trichoplax adhaerens reveals remarkable features at the origin of metazoan multicellularity.

Deletion of flbA results in increased secretome complexity and reduced secretion heterogeneity in colonies of Aspergillus niger

Determination of polycyclic aromatic hydrocarbons and polycylic aromatic sulfur heterocycles by high-performance liquid chromatography with fluorescence and atmospheric pressure chemical ionization mass spectrometry detection in seawater and [...]

Diet-induced neuropeptide expression: feasibility of quantifying extended and highly charged endogenous peptide sequences by selected reaction monitoring

Differential proteomics reveals the hallmarks of seed development in common bean (Phaseolus vulgaris L.).

Dimethyl isotope labeling assisted de novo peptide sequencing ⬇️

Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry.

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

Elucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.

Gaining efficiency by parallel quantification and identification of iTRAQ-labeled peptides using HCD and decision tree guided CID/ETD on an LTQ Orbitrap.

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

Identification of a tumor-specific allo-HLA-restricted γδTCR

Identification of putative substrates for the periplasmic chaperone YfgM in Escherichia coli using quantitative proteomics

Imaging of peptides in the rat brain using MALDI-FTICR mass spectrometry.

Improved identification of endogenous peptides from murine nervous tissue by multiplexed peptide extraction methods and multiplexed mass spectrometric analysis

Improved peptide identification by targeted fragmentation using CID, HCD and ETD on an LTQ-Orbitrap Velos.

Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

In-depth profiling of post-translational modifications on the related transcription factor complexes TFIID and SAGA.

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell-Specific Proteases

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

Monitoring light/dark association dynamics of multi-protein complexes in cyanobacteria using size exclusion chromatography-based proteomics.

Multistep mechanism of G-quadruplex resolution during DNA replication

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids ⬇️

Next-generation proteomics: towards an integrative view of proteome dynamics.

Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)n and (X)nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics

PaDuA: A Python Library for High-Throughput (Phospho)proteomics Data Analysis

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence

Probing the Proteome Response to Toluene Exposure in the Solvent Tolerant Pseudomonas putida S12

Profiling of diet-induced neuropeptide changes in rat brain by quantitative mass spectrometry

Progressive methylation of ageing histones by Dot1 functions as a timer.

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

Protein signatures associated with tumor cell dissemination in head and neck cancer

Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2)

Proteomics and Phosphoproteomics Profiling of Drug-Addicted BRAFi-Resistant Melanoma Cells

Quantitative Map of Proteome Dynamics during Neuronal Differentiation.

Quantitative Proteomics Illuminates a Functional Interaction between mDia2 and the Proteasome

Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons.

Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

Similar is not the same: differences in the function of the (hemi-)cellulolytic regulator XlnR (Xlr1/Xyr1) in filamentous fungi.

Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution.

Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage

Spatially Resolving the Secretome within the Mycelium of the Cell Factory Aspergillus niger

Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Display Altered Proteomes at Early Stages of Differentiation

Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.

Surface-enhanced resonance Raman spectroscopy as an identification tool in column liquid chromatography.

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

Temporal quantitative proteomics of mGluR-induced protein translation and phosphorylation in neurons

The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo

Tissue analysis with high-resolution imaging mass spectrometry.