Lista de obras - Filipa Marcelo - Dominio Público Uruguay

Beyond a Fluorescent Probe: Inhibition of Cell Division Protein FtsZ by mant-GTP Elucidated by NMR and Biochemical Approaches.

artículo científico publicado en 2015

Carbohydrate recognition at the minor-groove of the self-complementary duplex d(CGCGAATTCGCG)2 by a synthetic glyco-oligoamide.

artículo científico publicado en 2011

Cooperative hydrogen bonding in glyco-oligoamides: DNA minor groove binders in aqueous media

artículo científico publicado en 2014

D- andL-Mannose-Containingglyco-Oligoamides Show Distinct Recognition Properties When Interacting with DNA

article

Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin

artículo científico publicado en 2014

Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: potent and selective beta-N-acetylhexosaminidase inhibitors.

artículo científico publicado en 2009

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition

artículo científico publicado en 2015

Diametrically Opposed Carbenes on an α-Cyclodextrin: Synthesis, Characterization of Organometallic Complexes and Suzuki-Miyaura Coupling in Ethanol and in Water

Direct Experimental Evidence for the High Chemical Reactivity of α- and β-Xylopyranosides Adopting a 2,5B Conformation in Glycosyl Transfer

article

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

artículo científico publicado en 2011

Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).

artículo científico publicado en 2014

Fructose-Based Proline Analogues: Exploring the Prolyl trans/cis-Amide Rotamer Population in Model Peptides

article

Glycosyltransferase inhibitors: a promising strategy to pave a path from laboratory to therapy

Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands

artículo científico publicado en 2018

Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide

artículo científico publicado en 2015

Interactions of bacterial cell division protein FtsZ with C8-substituted guanine nucleotide inhibitors. A combined NMR, biochemical and molecular modeling perspective.

artículo científico publicado en 2013

Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3

scholarly article by Sabrina Santarsia et al published 11 September 2018 in ChemMedChem

Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

scientific article published on 13 January 2020

Molecular basis for inhibition of GH84 glycoside hydrolases by substituted azepanes: conformational flexibility enables probing of substrate distortion

artículo científico publicado en 2009

Molecular basis for the preferential recognition of β1,3-1,4-Glucans by the Family 11 Carbohydrate-Binding Module from Clostridium thermocellum

scientific article published on 03 December 2019

Molecular recognition of rosmarinic acid from Salvia sclareoides extracts by acetylcholinesterase: a new binding site detected by NMR spectroscopy.

artículo científico publicado en 2013

NHC-capped cyclodextrins (ICyDs): insulated metal complexes, commutable multicoordination sphere, and cavity-dependent catalysis

artículo científico publicado en 2013

Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR.

artículo científico publicado en 2013

Protein-Glycan Quinary Interactions in Crowding Environment Unveiled by NMR Spectroscopy

artículo científico publicado en 2017

Protein-carbohydrate interactions studied by NMR: from molecular recognition to drug design

artículo científico publicado en 2012

Rational design of a Tn antigen mimic

artículo científico publicado en 2011

Recent advances on the application of NMR methods to study the conformation and recognition properties of carbohydrates

article

Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides

artículo científico publicado en 2017

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations

scientific article published on 16 September 2019

Stereochemical assignment and first synthesis of the core of miharamycin antibiotics

artículo científico publicado en 2008

Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts.

artículo científico publicado en 2018

Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

artículo científico publicado en 2018

Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

artículo científico publicado en 2020

Structure–Activity Relationship Study of Opiorphin, a Human Dual Ectopeptidase Inhibitor with Antinociceptive Properties

Supercritical carbon dioxide extraction of astaxanthin and other carotenoids from the microalga Haematococcus pluvialis

article

Synthesis and conformational analysis of bicyclic mimics of α- and β-d-glucopyranosides adopting the biologically relevant 2,5B conformation

artículo científico publicado en 2012

Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase

artículo científico publicado en 2009

Synthesis, Conformational Analysis, and Evaluation as Glycosidase Inhibitors of Two Ether-Bridged Iminosugars

article

Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQ.

artículo científico publicado en 2011

The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin

scientific article published on 01 October 2019

The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.

artículo científico publicado en 2015

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

artículo científico publicado en 2017

Total Synthesis of the Epimer at C-6′ of the Miharamycin B Framework

α-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands

artículo científico publicado en 2012

Lista de obras de Filipa Marcelo

Beyond a Fluorescent Probe: Inhibition of Cell Division Protein FtsZ by mant-GTP Elucidated by NMR and Biochemical Approaches.

Carbohydrate recognition at the minor-groove of the self-complementary duplex d(CGCGAATTCGCG)2 by a synthetic glyco-oligoamide.

Cooperative hydrogen bonding in glyco-oligoamides: DNA minor groove binders in aqueous media

D- andL-Mannose-Containingglyco-Oligoamides Show Distinct Recognition Properties When Interacting with DNA

Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin

Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: potent and selective beta-N-acetylhexosaminidase inhibitors.

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition

Diametrically Opposed Carbenes on an α-Cyclodextrin: Synthesis, Characterization of Organometallic Complexes and Suzuki-Miyaura Coupling in Ethanol and in Water

Direct Experimental Evidence for the High Chemical Reactivity of α- and β-Xylopyranosides Adopting a 2,5B Conformation in Glycosyl Transfer

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).

Fructose-Based Proline Analogues: Exploring the Prolyl trans/cis-Amide Rotamer Population in Model Peptides

Glycosyltransferase inhibitors: a promising strategy to pave a path from laboratory to therapy

Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands

Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide

Interactions of bacterial cell division protein FtsZ with C8-substituted guanine nucleotide inhibitors. A combined NMR, biochemical and molecular modeling perspective.

Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3

Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

Molecular basis for inhibition of GH84 glycoside hydrolases by substituted azepanes: conformational flexibility enables probing of substrate distortion

Molecular basis for the preferential recognition of β1,3-1,4-Glucans by the Family 11 Carbohydrate-Binding Module from Clostridium thermocellum

Molecular recognition of rosmarinic acid from Salvia sclareoides extracts by acetylcholinesterase: a new binding site detected by NMR spectroscopy.

NHC-capped cyclodextrins (ICyDs): insulated metal complexes, commutable multicoordination sphere, and cavity-dependent catalysis

Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR.

Protein-Glycan Quinary Interactions in Crowding Environment Unveiled by NMR Spectroscopy

Protein-carbohydrate interactions studied by NMR: from molecular recognition to drug design

Rational design of a Tn antigen mimic

Recent advances on the application of NMR methods to study the conformation and recognition properties of carbohydrates

Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations

Stereochemical assignment and first synthesis of the core of miharamycin antibiotics

Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts.

Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

Structure–Activity Relationship Study of Opiorphin, a Human Dual Ectopeptidase Inhibitor with Antinociceptive Properties

Supercritical carbon dioxide extraction of astaxanthin and other carotenoids from the microalga Haematococcus pluvialis

Synthesis and conformational analysis of bicyclic mimics of α- and β-d-glucopyranosides adopting the biologically relevant 2,5B conformation

Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase

Synthesis, Conformational Analysis, and Evaluation as Glycosidase Inhibitors of Two Ether-Bridged Iminosugars

Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQ.

The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin

The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

Total Synthesis of the Epimer at C-6′ of the Miharamycin B Framework

α-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands