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Lista de obras de Ákos Nyerges

A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species

artículo científico publicado en 2016

A standardized workflow for surveying recombinases expands bacterial genome-editing capabilities.

artículo científico publicado en 2017

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

artículo científico publicado en 2019

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

artículo científico publicado en 2018

CRISPR-interference based modulation of mobile genetic elements in bacteria

CRISPR-interference-based modulation of mobile genetic elements in bacteria

artículo científico publicado en 2019

Conditional DNA repair mutants enable highly precise genome engineering

artículo científico publicado en 2014

Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.

artículo científico publicado en 2018

Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity

scientific article published on 10 December 2019

Enzyme promiscuity shapes adaptation to novel growth substrates

scientific article published on 08 April 2019

Enzyme promiscuity shapes evolutionary innovation and optimization

article

Genome-Wide Abolishment of Mobile Genetic Elements Using Genome Shuffling and CRISPR/Cas-Assisted MAGE Allows the Efficient Stabilization of a Bacterial Chassis

artículo científico publicado en 2017

Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network.

artículo científico publicado en 2014

High-Efficiency Multi-site Genomic Editing of Pseudomonas putida through Thermoinducible ssDNA Recombineering

artículo científico publicado en 2020

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

artículo científico publicado en 2020

Improved bacterial recombineering by parallelized protein discovery

artículo científico publicado en 2020

Improved bacterial recombineering by parallelized protein discovery

artículo científico publicado en 2020

Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

scientific article published on 01 August 2019

Mismatch repair hierarchy of Pseudomonas putida revealed by mutagenic ssDNA recombineering of the pyrF gene

scientific article published on 07 November 2019

Multiple-Site Diversification of Regulatory Sequences Enables Interspecies Operability of Genetic Devices

scientific article published on 18 December 2019

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

artículo científico publicado en 2018

Perturbation of iron homeostasis promotes the evolution of antibiotic resistance.

artículo científico publicado en 2014

Phenotypic heterogeneity promotes adaptive evolution.

artículo científico publicado en 2017

Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota

artículo científico publicado en 2018

Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

scientific article published on 23 August 2019

Rational design of balanced dual-targeting antibiotics with limited resistance

scientific article published on 05 October 2020

Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors

scientific article published on 11 February 2020

System-level genome editing in microbes

artículo científico publicado en 2016

Towards next-generation cell factories by rational genome-scale engineering

ssDNA recombineering boosts in vivo evolution of nanobodies displayed on bacterial surfaces

artículo científico publicado en 2021