Lista de obras - Ola Larsson - Dominio Público Uruguay

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

artículo científico publicado en 2016

A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E.

artículo científico publicado en 2009

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development

artículo científico publicado en 2012

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

artículo científico publicado en 2014

A stringent validation of mouse adipose tissue identity markers.

artículo científico publicado en 2015

Abstract 3575: Integration of estradiol signaling at the translational and transcriptional level in prostate cancer cells

Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR

artículo científico publicado en 2021

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF<sup>V600</sup> melanoma

artículo científico publicado en 2022

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

artículo científico publicado en 2007

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

scientific article published on 01 July 2019

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer

artículo científico

Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.

artículo científico publicado en 2006

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes

artículo científico publicado en 2015

Bactericidal antisense effects of peptide-PNA conjugates.

artículo científico publicado en 2001

Cancer as an ecomolecular disease and a neoplastic consortium

artículo científico publicado en 2017

Comparative microarray analysis

artículo científico publicado en 2006

Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1

artículo científico publicado en 2008

Considerations when using the significance analysis of microarrays (SAM) algorithm

artículo científico publicado en 2005

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference

artículo científico publicado en 2009

Correlation of regional emphysema and lung cancer: a lung tissue research consortium-based study.

artículo científico publicado en 2014

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

artículo científico publicado en 2012

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

artículo científico publicado en 2019

Distinct perturbation of the translatome by the antidiabetic drug metformin

artículo científico publicado en 2012

Distinct translational control in CD4+ T cell subsets

artículo científico publicado en 2013

Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs

artículo científico publicado en 2003

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation

artículo científico publicado en 2007

Eukaryotic initiation factor 4E binding protein family of proteins: sentinels at a translational control checkpoint in lung tumor defense

artículo científico publicado en 2009

Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

artículo científico publicado en 2007

Fibrotic extracellular matrix activates a profibrotic positive feedback loop

artículo científico publicado en 2014

Fibrotic myofibroblasts manifest genome-wide derangements of translational control

artículo científico publicado en 2008

Functional comparison of single- and double-stranded siRNAs in mammalian cells

artículo científico

Gene Expression – Time to Change Point of View? ⬇️

artículo científico publicado el 1 de enero de 2008

Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium

artículo científico publicado en 2013

Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy

artículo científico publicado en 2005

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

artículo científico publicado en 2009

IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.

artículo científico publicado en 2016

Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis.

artículo científico publicado en 2014

Identification of differential translation in genome wide studies

artículo científico publicado en 2010

Improved precision and accuracy for microarrays using updated probe set definitions

artículo científico publicado en 2007

Insulin receptor expression by human prostate cancers

artículo científico publicado en 2009

Interleukin-15 potentiates human natural killer cells to resist tumor-induced suppression through mTOR-regulated metabolic control.

artículo científico publicado en 2015

Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model.

artículo científico publicado en 2004

Lack of correct data format and comparability limits future integrative microarray research

artículo científico publicado en 2006

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection

artículo científico publicado en 2011

MNK2 governs the macrophage antiinflammatory phenotype

scientific article published on 19 October 2020

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

artículo científico publicado en 2007

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.

artículo científico publicado en 2014

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

artículo científico publicado en 2011

Pericyte-fibroblast transition promotes tumor growth and metastasis.

artículo científico publicado en 2016

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

artículo científico publicado en 2014

Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale

artículo científico publicado en 2014

Polysome-profiling in small tissue samples

artículo científico publicado en 2017

Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides

artículo científico publicado en 2002

RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity

artículo científico publicado en 2019

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.

artículo científico publicado en 2013

Regulatory element identification in subsets of transcripts: comparison and integration of current computational methods.

artículo científico publicado en 2009

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

scientific article published on 18 September 2020

Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference

artículo científico publicado en 2009

Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.

artículo científico publicado en 2014

The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.

artículo científico publicado en 2018

The expression signature of in vitro senescence resembles mouse but not human aging

artículo científico publicado en 2005

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis

artículo científico publicado en 2009

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

artículo científico publicado en 2021

Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker.

artículo científico publicado en 2002

Toward a genome-wide landscape of translational control

artículo científico publicado en 2013

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides

artículo científico publicado en 2017

Translational control of immune responses: from transcripts to translatomes

artículo científico

Translational control of the innate immune response through IRF-7

scientific article published in Nature

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

scientific article published on 26 September 2019

Tumor cell survival dependence on the DHX9 DExH-box helicase

scientific article published on 14 March 2016

Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis.

artículo científico publicado en 2013

Using functional genomics to study PINK1 and metabolic physiology.

artículo científico publicado en 2009

anota: Analysis of differential translation in genome-wide studies

artículo científico publicado en 2011

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

scientific article published on 13 November 2019

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

artículo científico publicado en 2010

iGEMS: an integrated model for identification of alternative exon usage events

artículo científico publicado en 2016

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.

artículo científico publicado en 2017

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

artículo científico publicado en 2015

mTOR-sensitive translation: Cleared fog reveals more trees

artículo científico publicado en 2017

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

artículo científico publicado en 2016

mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.

artículo científico publicado en 2013

mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

artículo científico publicado en 2010

nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

artículo científico publicado en 2016

p53-dependent translational control of senescence and transformation via 4E-BPs.

artículo científico publicado en 2009

Lista de obras de Ola Larsson

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E.

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

A stringent validation of mouse adipose tissue identity markers.

Abstract 3575: Integration of estradiol signaling at the translational and transcriptional level in prostate cancer cells

Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF<sup>V600</sup> melanoma

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer

Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes

Bactericidal antisense effects of peptide-PNA conjugates.

Cancer as an ecomolecular disease and a neoplastic consortium

Comparative microarray analysis

Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1

Considerations when using the significance analysis of microarrays (SAM) algorithm

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference

Correlation of regional emphysema and lung cancer: a lung tissue research consortium-based study.

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

Distinct perturbation of the translatome by the antidiabetic drug metformin

Distinct translational control in CD4+ T cell subsets

Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation

Eukaryotic initiation factor 4E binding protein family of proteins: sentinels at a translational control checkpoint in lung tumor defense

Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

Fibrotic extracellular matrix activates a profibrotic positive feedback loop

Fibrotic myofibroblasts manifest genome-wide derangements of translational control

Functional comparison of single- and double-stranded siRNAs in mammalian cells

Gene Expression – Time to Change Point of View? ⬇️

Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium

Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.

Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis.

Identification of differential translation in genome wide studies

Improved precision and accuracy for microarrays using updated probe set definitions

Insulin receptor expression by human prostate cancers

Interleukin-15 potentiates human natural killer cells to resist tumor-induced suppression through mTOR-regulated metabolic control.

Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model.

Lack of correct data format and comparability limits future integrative microarray research

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection

MNK2 governs the macrophage antiinflammatory phenotype

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

Pericyte-fibroblast transition promotes tumor growth and metastasis.

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale

Polysome-profiling in small tissue samples

Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides

RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.

Regulatory element identification in subsets of transcripts: comparison and integration of current computational methods.

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference

Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.

The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.

The expression signature of in vitro senescence resembles mouse but not human aging

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker.

Toward a genome-wide landscape of translational control

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides

Translational control of immune responses: from transcripts to translatomes

Translational control of the innate immune response through IRF-7

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

Tumor cell survival dependence on the DHX9 DExH-box helicase

Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis.

Using functional genomics to study PINK1 and metabolic physiology.

anota: Analysis of differential translation in genome-wide studies

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

iGEMS: an integrated model for identification of alternative exon usage events

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.

mTOR coordinates protein synthesis, mitochondrial activity and proliferation