Lista de obras - David Reverter - Dominio Público Uruguay

203 The crystal structure of a tri domain BPTI Kunitz inhibitor in complex with human carboxypeptidase A4 revealed a novel and non canonical inhibition mechanism

A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the Tri-Kunitz SmCI in complex with human CPA4

artículo científico publicado en 2013

A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25

artículo científico publicado en 2018

ATPase-dependent control of the Mms21 SUMO ligase during DNA repair

artículo científico publicado en 2015

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

artículo científico publicado en 2017

Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans

artículo científico publicado en 2019

Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility

artículo científico publicado en 2018

Crystal Structure of Novel Metallocarboxypeptidase Inhibitor from Marine Mollusk Nerita versicolor in Complex with Human Carboxypeptidase A4

artículo científico publicado en 2012

Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.

artículo científico publicado en 2018

Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera

artículo científico publicado en 2001

Crystal structure of c5321: a protective antigen present in uropathogenic Escherichia coli strains displaying an SLR fold

artículo científico publicado en 2013

Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity

artículo científico publicado en 2004

DNA activates the Nse2/Mms21 SUMO E3 ligase in the Smc5/6 complex

scientific article published on 16 May 2018

DYNLL/LC8 protein controls signal transduction through the Nek9/Nek6 signaling module by regulating Nek6 binding to Nek9.

artículo científico publicado en 2011

Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2

artículo científico publicado en 2012

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

artículo científico publicado en 2017

Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2.

artículo científico publicado en 1995

Flexibility analysis and structure comparison of two crystal forms of calcium-free human m-calpain

artículo científico publicado en 2002

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

artículo científico publicado en 2005

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization

artículo científico publicado en 2015

Molecular mechanisms in SUMO conjugation

artículo científico publicado en 2020

N-Terminal Protein Tails Act as Aggregation Protective Entropic Bristles: The SUMO Case

artículo científico publicado en 2014

Native structure protects SUMO proteins from aggregation into amyloid fibrils.

artículo científico publicado en 2012

Overexpression of Human Procarboxypeptidase A2 inPichia pastorisand Detailed Characterization of Its Activation Pathway

artículo científico publicado en 1998

Preparation of SUMO proteases and kinetic analysis using endogenous substrates

artículo científico publicado en 2009

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

artículo científico publicado en 2014

Regulation of USP28 deubiquitinating activity by SUMO conjugation ⬇️

artículo científico publicado en 2014

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.

artículo científico publicado en 2016

SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation

artículo científico publicado en 2013

Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins

artículo científico publicado en 2004

Structural Analysis of the Regulation of the DYNLL/LC8 Binding to Nek9 by Phosphorylation

artículo científico publicado en 2013

Structural Basis for Possible Calcium-Induced Activation Mechanisms of Calpains

scholarly article by David Reverter published in January 2001

Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.

artículo científico publicado en 2017

Structural analysis and evolution of specificity of the SUMO UFD E1-E2 interactions.

artículo científico publicado en 2017

Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs

artículo científico publicado en 2021

Structural characterization of the enzymes composing the arginine deiminase pathway in Mycoplasma penetrans

artículo científico publicado en 2012

Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution

scientific article published on 31 July 2019

Structural insights into the SENP6 Loop1 structure in complex with SUMO2

artículo científico publicado en 2014

Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2

artículo científico publicado en 2000

Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7

artículo científico publicado en 2008

Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.

artículo científico publicado en 2011

Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes

artículo científico publicado en 2019

The novel structure of a cytosolic M14 metallocarboxypeptidase (CCP) from Pseudomonas aeruginosa: a model for mammalian CCPs

artículo científico publicado en 2012

The structure of calcium-free human m-calpain: implications for calcium activation and function

artículo científico publicado en 2001

The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen ⬇️

artículo científico publicado el 1 de diciembre de 1997

Lista de obras de David Reverter

203 The crystal structure of a tri domain BPTI Kunitz inhibitor in complex with human carboxypeptidase A4 revealed a novel and non canonical inhibition mechanism

A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the Tri-Kunitz SmCI in complex with human CPA4

A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25

ATPase-dependent control of the Mms21 SUMO ligase during DNA repair

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans

Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility

Crystal Structure of Novel Metallocarboxypeptidase Inhibitor from Marine Mollusk Nerita versicolor in Complex with Human Carboxypeptidase A4

Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.

Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera

Crystal structure of c5321: a protective antigen present in uropathogenic Escherichia coli strains displaying an SLR fold

Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity

DNA activates the Nse2/Mms21 SUMO E3 ligase in the Smc5/6 complex

DYNLL/LC8 protein controls signal transduction through the Nek9/Nek6 signaling module by regulating Nek6 binding to Nek9.

Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2.

Flexibility analysis and structure comparison of two crystal forms of calcium-free human m-calpain

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization

Molecular mechanisms in SUMO conjugation

N-Terminal Protein Tails Act as Aggregation Protective Entropic Bristles: The SUMO Case

Native structure protects SUMO proteins from aggregation into amyloid fibrils.

Overexpression of Human Procarboxypeptidase A2 inPichia pastorisand Detailed Characterization of Its Activation Pathway

Preparation of SUMO proteases and kinetic analysis using endogenous substrates

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

Regulation of USP28 deubiquitinating activity by SUMO conjugation ⬇️

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.

SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation

Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins

Structural Analysis of the Regulation of the DYNLL/LC8 Binding to Nek9 by Phosphorylation

Structural Basis for Possible Calcium-Induced Activation Mechanisms of Calpains

Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.

Structural analysis and evolution of specificity of the SUMO UFD E1-E2 interactions.

Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs

Structural characterization of the enzymes composing the arginine deiminase pathway in Mycoplasma penetrans

Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution

Structural insights into the SENP6 Loop1 structure in complex with SUMO2

Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2

Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7

Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.

Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes

The novel structure of a cytosolic M14 metallocarboxypeptidase (CCP) from Pseudomonas aeruginosa: a model for mammalian CCPs

The structure of calcium-free human m-calpain: implications for calcium activation and function

The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen ⬇️