Lista de obras - Paul W. Fedak - Dominio Público Uruguay

Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

artículo científico publicado en 2020

Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry

artículo científico publicado en 2017

Adhesive-enhanced sternal closure to improve postoperative functional recovery: a pilot, randomized controlled trial

scientific article published on 01 October 2011

Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.

artículo científico publicado en 2006

Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know.

artículo científico publicado en 2018

Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4-Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects.

artículo científico publicado en 2017

Aortic diameter: The beginning of the end of an era

artículo científico publicado en 2018

Aortic valve malformations and pulmonary autograft root dilatation

scientific article published on 01 June 2002

Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration

artículo científico publicado en 2020

Assessing wall stresses in bicuspid aortic valve-associated aortopathy: Forecasting the perfect storm?

scientific article published on 31 March 2018

Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy

artículo científico publicado en 2013

Bicuspid aortic valve and the specialty clinic: are your patients at risk?

artículo científico publicado en 2017

Bicuspid aortic valve aortopathy: mechanistic and clinical insights from recent studies

artículo científico publicado en 2017

Bicuspid aortic valve syndrome: heterogeneous but predictable?

scientific article published on 03 January 2008

Bicuspid aortic valve-associated aortopathy: update on biomarkers.

artículo científico publicado en 2017

Bicuspid aortopathy and the development of individualized resection strategies

artículo científico publicado en 2014

Bridging to heart transplant with extracorporeal membrane oxygenation: Good or VAD?

artículo científico publicado en 2017

C-Reactive protein upregulates receptor for advanced glycation end products expression in human endothelial cells.

artículo científico publicado en 2006

C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis

artículo científico publicado en 2003

C-reactive protein alters antioxidant defenses and promotes apoptosis in endothelial progenitor cells

artículo científico publicado en 2006

C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease.

artículo científico publicado en 2004

C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle

artículo científico publicado en 2003

C-reactive protein upregulates complement-inhibitory factors in endothelial cells

artículo científico publicado en 2004

Can statin therapy alter the natural history of bicuspid aortic valves?

scientific article published on 01 June 2005

Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology/Canadian Society of Cardiac Surgery position statement on revascularization--multivessel coronary artery disease

artículo científico publicado en 2014

Canadian cardiac surgeons' perspectives on biomedical innovation.

artículo científico publicado en 2012

Cardiac progenitor cell sheet regenerates myocardium and renews hope for translation

artículo científico publicado en 2010

Cardiac regeneration with embryonic stem cells: historic recapitulation of heart transplantation

artículo científico publicado en 2008

Cardiac remodeling and failure From molecules to man (Part II).

artículo científico publicado en 2005

Cardiac restoration by cell transplantation.

artículo científico publicado en 2004

Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines

artículo científico publicado en 2006

Caveolin: a key target for modulating nitric oxide availability in health and disease.

artículo científico publicado en 2003

Cell therapy limits myofibroblast differentiation and structural cardiac remodeling: basic fibroblast growth factor-mediated paracrine mechanism.

artículo científico publicado en 2012

Cell transplantation preserves cardiac function after infarction by infarct stabilization: augmentation by stem cell factor.

artículo científico publicado en 2005

Cell transplantation preserves matrix homeostasis: a novel paracrine mechanism

artículo científico publicado en 2005

Cell transplantation to improve ventricular function in the failing heart.

artículo científico publicado en 2003

Cell-based gene therapy modifies matrix remodeling after a myocardial infarction in tissue inhibitor of matrix metalloproteinase-3-deficient mice

artículo científico publicado en 2009

Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy

artículo científico publicado en 2014

Clinical and pathophysiological implications of a bicuspid aortic valve

artículo científico publicado en 2002

Combined endothelial and myocardial protection by endothelin antagonism enhances transplant allograft preservation

artículo científico publicado en 2005

Comparison of outcomes and presentation in men-versus-women with bicuspid aortic valves undergoing aortic valve replacement.

artículo científico publicado en 2015

Determinants of health-related quality of life in adults with congenital heart disease

artículo científico publicado en 2007

Differential impact of mechanical unloading on structural and nonstructural components of the extracellular matrix in advanced human heart failure

artículo científico publicado en 2016

Does ischemic preconditioning afford clinically relevant cardioprotection?

artículo científico publicado en 2003

Effect of aortic aneurysm replacement on outcomes after bicuspid aortic valve surgery: validation of contemporary guidelines.

artículo científico publicado en 2014

Endothelial progenitor cells: new hope for a broken heart

artículo científico publicado en 2003

Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein

artículo científico publicado en 2002

Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins

artículo científico publicado en 2002

Enhanced IGF-1 expression improves smooth muscle cell engraftment after cell transplantation

artículo científico publicado en 2004

Enhancing sternal closure using Kryptonite bone adhesive: technical report

artículo científico publicado en 2011

Epicardial infarct repair with basic fibroblast growth factor-enhanced CorMatrix-ECM biomaterial attenuates postischemic cardiac remodeling

artículo científico publicado en 2013

Epicardial infarct repair with bioinductive extracellular matrix promotes vasculogenesis and myocardial recovery.

artículo científico publicado en 2016

Evaluation of a novel sutureless anastomotic connector: from endothelial function to mid-term clinical and angiographic follow-up.

artículo científico publicado en 2003

Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy

artículo científico publicado en 2017

Evolving concepts and technologies in mitral valve repair.

artículo científico publicado en 2008

Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling

artículo científico publicado en 2015

Fundamentals of reperfusion injury for the clinical cardiologist.

artículo científico publicado en 2002

Glitazones and heart failure: critical appraisal for the clinician

artículo científico publicado en 2003

Health technology assessments and innovation

artículo científico publicado en 2013

Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold

artículo científico publicado en 2017

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction

artículo científico publicado en 2009

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.

artículo científico publicado en 2014

Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation

artículo científico publicado en 2018

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

artículo científico publicado en 2018

Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism

artículo científico publicado en 2002

Hyperglycemia potentiates the proatherogenic effects of C-reactive protein: reversal with rosiglitazone.

artículo científico publicado en 2003

Increased endothelin-1 production in diabetic patients after cardioplegic arrest and reperfusion impairs coronary vascular reactivity: reversal by means of endothelin antagonism

artículo científico publicado en 2002

Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice

artículo científico publicado en 2006

Invited commentary

artículo científico publicado en 2003

Is Concomitant Aortopathy Unique With Bicuspid Aortic Valve Stenosis?

artículo científico publicado en 2016

Knowledge, attitudes, and practice patterns in surgical management of bicuspid aortopathy: a survey of 100 cardiac surgeons.

artículo científico publicado en 2013

Kryptonite bone cement prevents pathologic sternal displacement

artículo científico publicado en 2010

Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome.

artículo científico publicado en 2014

Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-β1.

artículo científico publicado en 2016

Na(+) current expression in human atrial myofibroblasts: identity and functional roles.

artículo científico publicado en 2014

Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells

artículo científico publicado en 2004

Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targets for pharmacologic manipulation

artículo científico publicado en 2002

Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement.

artículo científico publicado en 2017

Real estate of the bicuspid aorta: Location, location, location!

artículo científico publicado en 2016

Reply: Final Common Pathway of Aortic Dilation?: Heterogeneity of Aortic Wall Property Causes the Aneurysmal Change

artículo científico publicado en 2016

Reply: Importance of Stress Mapping of Aortic Wall in Aortic Valve Disease.

artículo científico publicado en 2016

Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction

artículo científico publicado en 2003

Response to letter regarding article, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy"

artículo científico publicado en 2014

Role of mutation and pharmacologic block of human KCNH2 in vasculogenesis and fetal mortality: partial rescue by transforming growth factor-β.

artículo científico publicado en 2015

Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy

artículo científico publicado en 2004

Safety and efficacy of prophylactic negative pressure wound therapy following open saphenous vein harvest in cardiac surgery: a feasibility study

artículo científico publicado en 2016

Seeing a tree through the forest: Precision medicine tools can enhance donor allocation in heart transplantation.

artículo científico publicado en 2017

Statin Use and Aneurysm Risk in Patients With Bicuspid Aortic Valve Disease

artículo científico publicado en 2015

Stem cell factor deficiency is vasculoprotective: unraveling a new therapeutic potential of imatinib mesylate

scientific article published on 24 August 2006

TIMP-3 deficiency accelerates cardiac remodeling after myocardial infarction.

artículo científico publicado en 2007

TIMP-3 deficiency leads to dilated cardiomyopathy

artículo científico publicado en 2004

Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury

artículo científico publicado en 2005

Tetrandrine reverses human cardiac myofibroblast activation and myocardial fibrosis

artículo científico publicado en 2015

The Cost of Frailty in Cardiac Surgery

artículo científico publicado en 2017

The molecular fingerprint of bicuspid aortopathy

artículo científico publicado en 2013

The role of the plasma from platelet concentrates in transfusion reactions

artículo científico publicado en 1994

Transplantation of cryopreserved muscle cells in dilated cardiomyopathy: effects on left ventricular geometry and function

artículo científico publicado en 2003

Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair

artículo científico publicado en 2018

Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping.

artículo científico publicado en 2015

Variation in the histopathological features of patients with ascending aortic aneurysms: a study of 111 surgically excised cases.

artículo científico publicado en 2007

Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation.

artículo científico publicado en 2003

Year in review: bicuspid aortopathy

artículo científico publicado en 2016

Lista de obras de Paul W. Fedak

Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry

Adhesive-enhanced sternal closure to improve postoperative functional recovery: a pilot, randomized controlled trial

Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.

Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know.

Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4-Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects.

Aortic diameter: The beginning of the end of an era

Aortic valve malformations and pulmonary autograft root dilatation

Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration

Assessing wall stresses in bicuspid aortic valve-associated aortopathy: Forecasting the perfect storm?

Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy

Bicuspid aortic valve and the specialty clinic: are your patients at risk?

Bicuspid aortic valve aortopathy: mechanistic and clinical insights from recent studies

Bicuspid aortic valve syndrome: heterogeneous but predictable?

Bicuspid aortic valve-associated aortopathy: update on biomarkers.

Bicuspid aortopathy and the development of individualized resection strategies

Bridging to heart transplant with extracorporeal membrane oxygenation: Good or VAD?

C-Reactive protein upregulates receptor for advanced glycation end products expression in human endothelial cells.

C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis

C-reactive protein alters antioxidant defenses and promotes apoptosis in endothelial progenitor cells

C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease.

C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle

C-reactive protein upregulates complement-inhibitory factors in endothelial cells

Can statin therapy alter the natural history of bicuspid aortic valves?

Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology/Canadian Society of Cardiac Surgery position statement on revascularization--multivessel coronary artery disease

Canadian cardiac surgeons' perspectives on biomedical innovation.

Cardiac progenitor cell sheet regenerates myocardium and renews hope for translation

Cardiac regeneration with embryonic stem cells: historic recapitulation of heart transplantation

Cardiac remodeling and failure From molecules to man (Part II).

Cardiac restoration by cell transplantation.

Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines

Caveolin: a key target for modulating nitric oxide availability in health and disease.

Cell therapy limits myofibroblast differentiation and structural cardiac remodeling: basic fibroblast growth factor-mediated paracrine mechanism.

Cell transplantation preserves cardiac function after infarction by infarct stabilization: augmentation by stem cell factor.

Cell transplantation preserves matrix homeostasis: a novel paracrine mechanism

Cell transplantation to improve ventricular function in the failing heart.

Cell-based gene therapy modifies matrix remodeling after a myocardial infarction in tissue inhibitor of matrix metalloproteinase-3-deficient mice

Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy

Clinical and pathophysiological implications of a bicuspid aortic valve

Combined endothelial and myocardial protection by endothelin antagonism enhances transplant allograft preservation

Comparison of outcomes and presentation in men-versus-women with bicuspid aortic valves undergoing aortic valve replacement.

Determinants of health-related quality of life in adults with congenital heart disease

Differential impact of mechanical unloading on structural and nonstructural components of the extracellular matrix in advanced human heart failure

Does ischemic preconditioning afford clinically relevant cardioprotection?

Effect of aortic aneurysm replacement on outcomes after bicuspid aortic valve surgery: validation of contemporary guidelines.

Endothelial progenitor cells: new hope for a broken heart

Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein

Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins

Enhanced IGF-1 expression improves smooth muscle cell engraftment after cell transplantation

Enhancing sternal closure using Kryptonite bone adhesive: technical report

Epicardial infarct repair with basic fibroblast growth factor-enhanced CorMatrix-ECM biomaterial attenuates postischemic cardiac remodeling

Epicardial infarct repair with bioinductive extracellular matrix promotes vasculogenesis and myocardial recovery.

Evaluation of a novel sutureless anastomotic connector: from endothelial function to mid-term clinical and angiographic follow-up.

Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy

Evolving concepts and technologies in mitral valve repair.

Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling

Fundamentals of reperfusion injury for the clinical cardiologist.

Glitazones and heart failure: critical appraisal for the clinician

Health technology assessments and innovation

Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.

Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism

Hyperglycemia potentiates the proatherogenic effects of C-reactive protein: reversal with rosiglitazone.

Increased endothelin-1 production in diabetic patients after cardioplegic arrest and reperfusion impairs coronary vascular reactivity: reversal by means of endothelin antagonism

Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice

Invited commentary

Is Concomitant Aortopathy Unique With Bicuspid Aortic Valve Stenosis?

Knowledge, attitudes, and practice patterns in surgical management of bicuspid aortopathy: a survey of 100 cardiac surgeons.

Kryptonite bone cement prevents pathologic sternal displacement

Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome.

Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-β1.

Na(+) current expression in human atrial myofibroblasts: identity and functional roles.

Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells

Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targets for pharmacologic manipulation

Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement.

Real estate of the bicuspid aorta: Location, location, location!