Lista de obras - Dolores Viña - Dominio Público Uruguay

1,2-Disubstituted cyclohexane nucleosides: comparative study for the synthesis of cis and trans adenosine analogues

article published in 2005

1,2-disubstituted cyclohexane carbocyclic analogues of nucleosides.

artículo científico publicado en 2001

3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

artículo científico publicado en 2015

3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease

scholarly article by Dolores Viña et al published 2012 in MedChemComm

8-Substituted 3-arylcoumarins as potent and selective MAO-B inhibitors: synthesis, pharmacological evaluation, and docking studies

artículo científico publicado en 2012

A Novel Series of 3,4-Disubstituted Dihydropyrazoles: Synthesis and Evaluation for MAO Enzyme Inhibition

A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors

artículo científico publicado en 2009

Activation of PKA and Epac proteins by cyclic AMP depletes intracellular calcium stores and reduces calcium availability for vasoconstriction

artículo científico publicado en 2016

Alignment-free prediction of a drug-target complex network based on parameters of drug connectivity and protein sequence of receptors.

artículo científico publicado en 2009

Antidepressant-like profile and MAO-A inhibitory activity of 4-propyl-2H-benzo[h]-chromen-2-one

artículo científico publicado en 2010

Assignment of the1H and13C NMR signals of some hydroxyphenylcoumarins

scientific article published on 01 January 2007

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors ⬇️

artículo científico publicado el 5 de diciembre de 2010

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

artículo científico publicado en 2011

Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors

artículo científico publicado en 2012

Computational Drug Target Screening through Protein Interaction Profiles

artículo científico publicado en 2016

Editorial: monoamine oxidase as a target in medicinal chemistry and drug discovery

scientific article published on 01 January 2012

Exploring Nitrostyrene as a Scaffold for a New Class a of Monoamine Oxidase Inhibitors

Hydroxycoumarins as selective MAO-B inhibitors

artículo científico publicado en 2011

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

artículo científico publicado en 2014

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

artículo científico publicado en 2013

MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins

artículo científico publicado en 2011

MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, study, and docking calculations

artículo científico publicado en 2017

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins

artículo científico publicado en 2014

Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

artículo científico publicado en 2018

New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

artículo científico publicado en 2016

New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

artículo científico publicado en 2019

New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors

artículo científico publicado en 2010

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

artículo científico publicado en 2013

Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease

artículo científico publicado en 2018

Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

artículo científico publicado en 2014

Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides

artículo científico publicado en 2003

Pyrazolo[3,4,5-de]phthalazine. Syntheses of a practically unknown heterocyclic system

QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices.

artículo científico publicado en 2005

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

artículo científico publicado en 2008

Regioselective Synthesis of 1-Alkyl- or 1-Aryl-1H-indazoles via Copper-Catalyzed Cyclizations of 2-Haloarylcarbonylic Compounds

scientific article published on 01 February 2007

Regioselective synthesis of O2- and O6-cyclopyrimidine nucleoside analogues

Stereocontrolled Synthesis of Ara-Type Cyclohexenyl Nucleosides

Stochastic entropy QSAR for the in silico discovery of anticancer compounds: prediction, synthesis, and in vitro assay of new purine carbanucleosides

artículo científico publicado en 2005

Synthesis and complete assignment of the 1H and 13C NMR signals of some oxopyrancoumarin and oxofuropyrancoumarin derivatives.

artículo científico publicado en 2008

Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors

artículo científico publicado en 2009

Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

artículo científico publicado en 2017

Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors

artículo científico publicado en 2011

Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives

Synthesis of 1,2-Disubstituted Carbocyclic Nucleoside Analogues of Cytidine

Synthesis of 1-[2-(Hydroxymethyl)cyclohexyl]pyrimidine Analogues of Nucleosides: A Comparative Study

Synthesis of 3′-O-phosphonomethyl nucleosides with an adenine base moiety

Synthesis of Carbocyclic Pyrimidine Nucleosides Using theMitsunobuReaction:O2-vs. N1-Alkylation

Synthesis of Regioisomeric Functionalized Benzodifurans and Angelicins

scholarly article by Elias Quezada et al published July 2009 in Helvetica Chimica Acta

Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2H)-one derivatives as novel cholinesterase inhibitors

scholarly article in RSC Advances, vol. 6 no. 52, 2016

Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.

artículo científico publicado en 2014

Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

artículo científico publicado en 2014

The neuroprotection exerted by memantine, minocycline and lithium, against neurotoxicity of CSF from patients with amyotrophic lateral sclerosis, is antagonized by riluzole

artículo científico publicado en 2013

Lista de obras de Dolores Viña

1,2-Disubstituted cyclohexane nucleosides: comparative study for the synthesis of cis and trans adenosine analogues

1,2-disubstituted cyclohexane carbocyclic analogues of nucleosides.

3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease

8-Substituted 3-arylcoumarins as potent and selective MAO-B inhibitors: synthesis, pharmacological evaluation, and docking studies

A Novel Series of 3,4-Disubstituted Dihydropyrazoles: Synthesis and Evaluation for MAO Enzyme Inhibition

A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors

Activation of PKA and Epac proteins by cyclic AMP depletes intracellular calcium stores and reduces calcium availability for vasoconstriction

Alignment-free prediction of a drug-target complex network based on parameters of drug connectivity and protein sequence of receptors.

Antidepressant-like profile and MAO-A inhibitory activity of 4-propyl-2H-benzo[h]-chromen-2-one

Assignment of the1H and13C NMR signals of some hydroxyphenylcoumarins

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors ⬇️

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors

Computational Drug Target Screening through Protein Interaction Profiles

Editorial: monoamine oxidase as a target in medicinal chemistry and drug discovery

Exploring Nitrostyrene as a Scaffold for a New Class a of Monoamine Oxidase Inhibitors

Hydroxycoumarins as selective MAO-B inhibitors

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins

MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, study, and docking calculations

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins

Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease

Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides

Pyrazolo[3,4,5-de]phthalazine. Syntheses of a practically unknown heterocyclic system

QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices.

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Regioselective Synthesis of 1-Alkyl- or 1-Aryl-1H-indazoles via Copper-Catalyzed Cyclizations of 2-Haloarylcarbonylic Compounds

Regioselective synthesis of O2- and O6-cyclopyrimidine nucleoside analogues

Stereocontrolled Synthesis of Ara-Type Cyclohexenyl Nucleosides

Stochastic entropy QSAR for the in silico discovery of anticancer compounds: prediction, synthesis, and in vitro assay of new purine carbanucleosides

Synthesis and complete assignment of the 1H and 13C NMR signals of some oxopyrancoumarin and oxofuropyrancoumarin derivatives.

Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors

Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors

Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors

Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives

Synthesis of 1,2-Disubstituted Carbocyclic Nucleoside Analogues of Cytidine

Synthesis of 1-[2-(Hydroxymethyl)cyclohexyl]pyrimidine Analogues of Nucleosides: A Comparative Study

Synthesis of 3′-O-phosphonomethyl nucleosides with an adenine base moiety

Synthesis of Carbocyclic Pyrimidine Nucleosides Using theMitsunobuReaction:O2-vs. N1-Alkylation

Synthesis of Regioisomeric Functionalized Benzodifurans and Angelicins

Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2H)-one derivatives as novel cholinesterase inhibitors

Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.

Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

The neuroprotection exerted by memantine, minocycline and lithium, against neurotoxicity of CSF from patients with amyotrophic lateral sclerosis, is antagonized by riluzole