Filtros de búsqueda

Lista de obras de Marco Mor

2-N-acylaminoalkylindoles: design and quantitative structure-activity relationship studies leading to MT2-selective melatonin antagonists

artículo científico publicado en 2001

2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists.

artículo científico publicado en 1998

3-Aminoazetidin-2-one derivatives as N-acylethanolamine acid amidase (NAAA) inhibitors suitable for systemic administration

artículo científico publicado en 2014

5-Benzylidene-hydantoins: synthesis and antiproliferative activity on A549 lung cancer cell line

artículo científico publicado en 2009

5-benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity.

artículo científico publicado en 2006

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation.

artículo científico publicado en 2015

A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations

artículo científico publicado en 2012

A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo

artículo científico publicado en 2009

Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats

artículo científico publicado en 2015

Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.

artículo científico publicado en 2013

An endocannabinoid mechanism for stress-induced analgesia.

artículo científico publicado en 2005

Analysis of illicit dietary supplements sold in the Italian market: identification of a sildenafil thioderivative as adulterant using UPLC-TOF/MS and GC/MS

artículo científico publicado en 2014

Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models

artículo científico publicado en 2005

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.

artículo científico publicado en 2010

Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats

artículo científico publicado en 2015

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

artículo científico publicado en 2005

Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress

artículo científico publicado en 2007

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models

artículo científico publicado en 2012

Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam

artículo científico publicado en 2012

Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors

artículo científico publicado en 2005

Application of a SCC-DFTB QM/MM approach to the investigation of the catalytic mechanism of fatty acid amide hydrolase

artículo científico publicado en 2011

Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs

artículo científico publicado en 2017

Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines

scientific article published on 02 December 2019

Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis

artículo científico publicado en 2015

Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability ⬇️

artículo científico publicado el 21 de julio de 2011

Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: synthesis, binding affinity and intrinsic activity for MT(1) and MT(2) melatonin receptors

artículo científico publicado en 2011

Brain pharmacokinetics of non-imidazole biphenyl H3 receptor antagonists: a liquid chromatography/electrospray-mass spectrometry and ex vivo binding study in rats.

artículo científico publicado en 2012

Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety.

artículo científico publicado en 2015

Catalytic, asymmetric hypervinylogous Mukaiyama aldol reactions of extended furan-based silyl enolates

scientific article published on 11 August 2011

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation.

artículo científico publicado en 2004

Chiral NMR discrimination of the diastereoisomeric salts of the H3-antagonist 2-[3-(1H-imidazol-4-ylmethyl)piperidin-1-yl]-1H-benzimidazole.

artículo científico publicado en 2009

Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria

artículo científico publicado en 2020

Cholinergic agents structurally related to furtrethonium. 2. Synthesis and antimuscarinic activity of a series of N-[5-[(1'-substituted-acetoxy) methyl]-2-furfuryl]dialkylamines

scientific article published on 01 December 1994

Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate.

artículo científico publicado en 2016

Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction.

artículo científico publicado en 2014

Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists.

artículo científico publicado en 2015

Complex product composition generates risks for generic substitution also with dosage forms for intravenous administration.

artículo científico publicado en 2013

Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth

artículo científico publicado en 2018

Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase

artículo científico publicado en 2006

Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study

artículo científico publicado en 1997

Correction to Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo

scientific article published on 28 September 2020

Correction to Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8.

artículo científico publicado en 2017

Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamate FAAH inhibitors

artículo científico publicado en 2007

Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas.

artículo científico publicado en 2011

Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies

artículo científico publicado en 2004

Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.

artículo científico publicado en 2006

Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors.

artículo científico publicado en 2003

Development and validation of a LC-MS method with electrospray ionization for the determination of the imidazole H3 antagonist ROS203 in rat plasma

artículo científico publicado en 2007

Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain.

artículo científico publicado en 2011

Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).

artículo científico publicado en 2013

Discovery of potent and reversible monoacylglycerol lipase inhibitors.

artículo científico publicado en 2009

Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions.

artículo científico publicado en 2012

Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines

artículo científico publicado en 2008

Epidermal growth factor receptor irreversible inhibitors: chemical exploration of the cysteine-trap portion.

artículo científico

Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer

artículo científico

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines

Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return.

artículo científico publicado en 2016

FGF trapping inhibits multiple myeloma growth through c-Myc degradation-induced mitochondrial oxidative stress

artículo científico publicado en 2020

Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents

artículo científico publicado en 2016

Fatty acid amide hydrolase inhibitors: a patent review (2009-2014)

artículo científico publicado en 2015

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.

artículo científico publicado en 2016

Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines.

artículo científico publicado en 2010

H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles

artículo científico publicado en 1997

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines

artículo científico publicado en 2015

Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit

scientific article published on 04 September 2018

Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754).

artículo científico publicado en 2007

Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling

artículo científico publicado en 2007

Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors

artículo científico publicado en 2004

Indole-based analogs of melatonin: in vitro antioxidant and cytoprotective activities

artículo científico publicado en 2004

Insights in the mechanism of action and inhibition of N-acylethanolamine acid amidase by means of computational methods

artículo científico publicado en 2014

Insights into the mechanism and inhibition of fatty acid amide hydrolase from quantum mechanics/molecular mechanics (QM/MM) modelling.

artículo científico publicado en 2009

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueou

artículo científico publicado en 2016

Irreversible inhibition of epidermal growth factor receptor activity by 3-aminopropanamides.

artículo científico publicado en 2012

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.

artículo científico publicado en 2016

L718Q Mutation as New Mechanism of Acquired Resistance to AZD9291 in EGFR-Mutated NSCLC.

artículo científico publicado en 2016

L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib.

artículo científico publicado en 2018

Liquid chromatography-mass spectrometric method for determination of the non-imidazole H3-receptor antagonist UPR1056 in rat plasma

artículo científico publicado en 2011

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

scientific journal article

Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors.

artículo científico publicado en 2013

MT1-selective melatonin receptor ligands: synthesis, pharmacological evaluation, and molecular dynamics investigation of N-{[(3-O-substituted)anilino]alkyl}amides.

artículo científico publicado en 2012

Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment ⬇️

artículo científico publicado el 1 de diciembre de 2011

Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders

artículo científico publicado en 2008

Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study

artículo científico publicado en 1998

Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines.

artículo científico publicado en 2011

Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8.

artículo científico publicado en 2017

Modulation of anxiety through blockade of anandamide hydrolysis

artículo científico publicado en 2003

Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.

artículo científico publicado en 2013

Monoglyceride lipase: Structure and inhibitors.

artículo científico

N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis and Structure–Activity and Structure–Property Relationships

artículo científico publicado en 2012

N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands

artículo científico publicado en 2009

N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands

artículo científico publicado en 2007

N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition

scientific article published on 26 March 2020

New classes of potent heparanase inhibitors from ligand-based virtual screening

artículo científico publicado en 2020

Nonempirical energetic analysis of reactivity and covalent inhibition of fatty acid amide hydrolase

artículo científico publicado en 2013

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity

scientific article published on 30 July 2018

Novel Symmetrical Benzazolyl Derivatives Endowed with Potent anti-Heparanase Activity

artículo científico publicado en 2018

Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons

artículo científico publicado en 2015

Pharmacokinetic and pharmacodynamic evaluation of ramelteon : an insomnia therapy

artículo científico

Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties.

artículo científico publicado en 2006

Pharmacological inhibition of FAAH activity in rodents: A promising pharmacological approach for psychological-cardiac comorbidity?

artículo científico publicado en 2016

Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).

artículo científico publicado en 2006

Pharmacological tools in endocannabinoid neurobiology

scientific article published on 01 January 2009

Physical Nature of Fatty Acid Amide Hydrolase Interactions with Its Inhibitors: Testing a Simple Nonempirical Scoring Model

artículo científico publicado en 2014

Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental study

artículo científico publicado en 2014

Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand

scientific journal article

Pushing the boundaries of vinylogous reactivity: catalytic enantioselective mukaiyama aldol reactions of highly unsaturated 2-silyloxyindoles

artículo científico publicado en 2015

QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation.

artículo científico publicado en 2005

Qualitative structure-metabolism relationships in the hydrolysis of carbamates.

artículo científico publicado en 2010

Quantum mechanics/molecular mechanics modeling of covalent addition between EGFR-cysteine 797 and N-(4-anilinoquinazolin-6-yl) acrylamide.

artículo científico publicado en 2015

Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors

artículo científico publicado en 2013

Reassessing the melatonin pharmacophore--enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue

artículo científico publicado en 2006

Recent advances in the development of melatonin MT(1) and MT(2) receptor agonists.

scientific article published on August 2010

ST7612AA1, a thioacetate-ω(γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors

artículo científico publicado en 2014

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

artículo científico publicado en 2009

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

artículo científico publicado en 2005

Statistical analysis on a series of glycine antagonists

artículo científico publicado en 2000

Structural Fluctuations in Enzyme-Catalyzed Reactions: Determinants of Reactivity in Fatty Acid Amide Hydrolase from Multivariate Statistical Analysis of Quantum Mechanics/Molecular Mechanics Paths

artículo científico publicado en 2010

Structure-affinity relationships of indole-based melatonin analogs.

artículo científico publicado en 1999

Structure-based virtual screening of MT2 melatonin receptor: influence of template choice and structural refinement.

artículo científico publicado en 2013

Structure–Activity Relationships and Mechanism of Action of Eph–ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor ⬇️

artículo científico publicado el 23 de abril de 2012

Structure–property relationships on histamine H3-antagonists: binding of phenyl-substituted alkylthioimidazole derivatives to rat plasma proteins

artículo científico publicado en 2000

Synthesis and Structure-Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring

artículo científico publicado en 2006

Synthesis and biological assays of new H3-antagonists with imidazole and imidazoline polar groups

artículo científico publicado en 2000

Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series

artículo científico publicado en 2005

Synthesis and characterization of new bivalent agents as melatonin- and histamine H3-ligands

artículo científico publicado en 2014

Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates.

artículo científico publicado en 2008

Synthesis and stability in biological media of 1H-imidazole-1-carboxylates of ROS203, an antagonist of the histamine H3 receptor.

artículo científico publicado en 2008

Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors

artículo científico publicado en 2013

Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors.

artículo científico publicado en 2013

Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity

artículo científico publicado en 2008

Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors.

artículo científico publicado en 2010

Synthesis and structure-activity relationships of a series of pyrrole cannabinoid receptor agonists

artículo científico publicado en 2003

Synthesis and structure-activity relationships of amino acid conjugates of cholanic acid as antagonists of the EphA2 receptor.

artículo científico publicado en 2013

Synthesis and three-dimensional quantitative structure-activity relationship analysis of H3 receptor antagonists containing a neutral heterocyclic polar group

artículo científico publicado en 2003

Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.

artículo científico publicado en 2013

Synthesis, Structural Elucidation, and Biological Evaluation of NSC12, an Orally Available Fibroblast Growth Factor (FGF) Ligand Trap for the Treatment of FGF-Dependent Lung Tumors.

artículo científico publicado en 2016

Synthesis, antioxidant activity and structure-activity relationships for a new series of 2-(N-acylaminoethyl)indoles with melatonin-like cytoprotective activity.

artículo científico publicado en 2006

Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists.

artículo científico publicado en 2004

Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists

artículo científico publicado en 2007

Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands.

artículo científico publicado en 2001

Synthesis, pharmacological evaluation, and structure-activity relationships of benzopyran derivatives with potent SERM activity

artículo científico publicado en 2004

Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands

artículo científico publicado en 2018

The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment

artículo científico

The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity

artículo científico publicado en 2009

The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice

artículo científico publicado en 2007

The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues

artículo científico publicado en 2006

Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.

artículo científico publicado en 2003

Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin derivatives

artículo científico publicado en 2011

Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties

scientific article published on 13 April 2014

Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity.

artículo científico publicado en 2004

URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.

artículo científico publicado en 2007

Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling

artículo científico publicado en 2011

UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations.

artículo científico publicado en 2014

Validation of a histamine H3 receptor model through structure-activity relationships for classical H3 antagonists

artículo científico publicado en 2005

pH-partition profiles of 4-(3-oxo-1,2-benzisothiazolin-2-yl)phenyl and phenoxyalkanoic acids

artículo científico publicado en 2003

Δ(5)-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system

artículo científico publicado en 2015

β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda