Lista de obras - Alan J Williams - Dominio Público Uruguay

A Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes

artículo científico publicado en 2015

A model for ionic conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum ⬇️

artículo científico publicado el 1 de septiembre de 1992

A model of the putative pore region of the cardiac ryanodine receptor channel

artículo científico publicado en 2004

A novel and rapid approach to isolating functional ryanodine receptors

artículo científico publicado en 2002

A possible molecular mechanism for 'stunning' of the myocardium.

artículo científico publicado en 1991

A single isotope method for the measurement of the volume of the mitochondrial inner compartment

artículo científico publicado en 1980

ATP-induced stimulation of calcium binding to cardiac sarcolemma ⬇️

artículo científico publicado el 30 de marzo de 1979

Activation of the sheep cardiac Ca2+ release channel by simple heteroaromatics.

artículo científico publicado en 2004

Activation of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by analogues of sulmazole.

artículo científico publicado en 1994

Adenosine discriminates between the caffeine and adenine nucleotide sites on the sheep cardiac sarcoplasmic reticulum calcium-release channel

artículo científico publicado en 1994

An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels

artículo científico publicado en 2003

An assay for inorganic orthophosphate in the presence of alkaloids and related drugs

artículo científico publicado en 1977

Asymmetric block of a monovalent cation-selective channel of rabbit cardiac sarcoplasmic reticulum by succinyl choline

scientific article published on 01 January 1985

Block of the ryanodine receptor channel by neomycin is relieved at high holding potentials

artículo científico publicado en 2002

Block of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by tetra-alkyl ammonium cations

artículo científico publicado en 1992

Calcium-proton exchange in cardiac and liver mitochondria ⬇️

artículo científico publicado el 15 de enero de 1979

Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain.

artículo científico publicado en 2016

Cardiovascular receptors and calcium

artículo científico publicado en 1980

Cation conduction in the calcium release channel of the cardiac sarcoplasmic reticulum under physiological and pathophysiological conditions.

artículo científico publicado en 1993

Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.

artículo científico publicado en 2009

Characterization of a Ca(2+)-dependent anion channel from sheep tracheal epithelium incorporated into planar bilayers.

artículo científico publicado en 1991

Characterization of the ryanodine receptor-Ca2+ release channel from the thoracic tissues of the lepidopteran insect Heliothis virescens

artículo científico publicado en 2001

Charged local anesthetics block ionic conduction in the sheep cardiac sarcoplasmic reticulum calcium release channel.

artículo científico publicado en 1993

Chicken skeletal muscle ryanodine receptor isoforms: ion channel properties

artículo científico publicado en 1994

Comparison of the protein constituents of sarcoplasmic reticulum isolated from rat skeletal and cardiac muscle.

artículo científico publicado en 1974

Contamination of a cardiac sarcolemmal preparation with endothelial plasma membrane.

artículo científico publicado en 1986

Cyclic ADP-ribose and related compounds activate sheep skeletal sarcoplasmic reticulum Ca2+ release channel

artículo científico publicado en 1995

Cyclic ADP-ribose competes with ATP for the adenine nucleotide binding site on the cardiac ryanodine receptor Ca(2+)-release channel

artículo científico publicado en 1994

Dantrolene rescues aberrant N-terminus intersubunit interactions in mutant pro-arrhythmic cardiac ryanodine receptors.

artículo científico publicado en 2014

Digoxin activates sarcoplasmic reticulum Ca(2+)-release channels: a possible role in cardiac inotropy.

artículo científico publicado en 1993

Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart.

artículo científico publicado en 2012

Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum ⬇️

artículo científico publicado el 1 de septiembre de 1992

Do inactivation mechanisms rather than adaptation hold the key to understanding ryanodine receptor channel gating?

artículo científico publicado en 2000

Effect of R56865 on cardiac sarcoplasmic reticulum function and its role as an antagonist of digoxin at the sarcoplasmic reticulum calcium release channel.

artículo científico publicado en 1995

Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.

artículo científico publicado en 2016

Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel

artículo científico publicado en 1996

Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2)

artículo científico publicado en 2004

Evidence for Ca(2+) activation and inactivation sites on the luminal side of the cardiac ryanodine receptor complex

artículo científico publicado en 2000

Evidence for negative charge in the conduction pathway of the cardiac ryanodine receptor channel provided by the interaction of K+ channel N-type inactivation peptides

artículo científico publicado en 1998

Evidence for novel caffeine and Ca2+ binding sites on the lobster skeletal ryanodine receptor

artículo científico publicado en 1999

Excess noise in modified conductance states following the interaction of ryanoids with cardiac ryanodine receptor channels

artículo científico publicado en 2002

Functional characterisation of the ryanodine receptor purified from sheep cardiac muscle sarcoplasmic reticulum

artículo científico publicado en 1991

Functional characterization of the cardiac ryanodine receptor pore-forming region.

artículo científico publicado en 2013

Gating of the native and purified cardiac SR Ca(2+)-release channel with monovalent cations as permeant species

artículo científico publicado en 1994

Glycolytic pathway intermediates activate cardiac ryanodine receptors

artículo científico publicado en 1998

How does ryanodine modify ion handling in the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel?

artículo científico publicado en 1994

Hypoxia and calcium ⬇️

artículo científico publicado el 1 de julio de 1979

Insights into the gating mechanism of the ryanodine-modified human cardiac Ca2+-release channel (ryanodine receptor 2).

artículo científico publicado en 2014

Ion conduction and discrimination in the sarcoplasmic reticulum ryanodine receptor/calcium-release channel

artículo científico publicado en 1992

Ion conduction and selectivity in the ryanodine receptor channel

artículo científico publicado en 2002

Large tetraalkyl ammonium cations produce a reduced conductance state in the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel ⬇️

artículo científico publicado el 1 de mayo de 1992

Light at the end of the Ca(2+)-release channel tunnel: structures and mechanisms involved in ion translocation in ryanodine receptor channels

artículo científico publicado en 2001

Markovian models of low and high activity levels of cardiac ryanodine receptors

artículo científico publicado en 2001

Massive Accumulation of Myofibroblasts in the Critical Isthmus Is Associated With Ventricular Tachycardia Inducibility in Post-Infarct Swine Heart.

artículo científico publicado en 2017

Measurement of ionic exchange in organelle suspensions with ion-selective electrodes [proceedings]

artículo científico publicado el 1 de abril de 1979

Measuring the length of the pore of the sheep cardiac sarcoplasmic reticulum calcium-release channel using related trimethylammonium ions as molecular calipers

artículo científico publicado en 1995

Mechanisms of caffeine activation of single calcium-release channels of sheep cardiac sarcoplasmic reticulum

artículo científico publicado en 1990

Modification of gating of an airway epithelial chloride channel by 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB)

artículo científico publicado en 1992

Modification of the conductance and gating properties of ryanodine receptors by suramin.

artículo científico publicado en 1996

Modification of the gating of the cardiac sarcoplasmic reticulum Ca(2+)-release channel by H2O2 and dithiothreitol.

artículo científico publicado en 1994

Modulation of single Ca2+-dependent K+-channel activity by protein phosphorylation

scientific article published on 01 June 1985

Molecular cloning, characterisation and mRNA expression of the ryanodine receptor from the peach-potato aphid, Myzus persicae.

artículo científico publicado en 2014

Monovalent cation conductance in the ryanodine receptor-channel of sheep cardiac muscle sarcoplasmic reticulum

scientific article published on 01 August 1991

Myocardial calcium signalling and arrhythmia pathogenesis.

artículo científico publicado en 2004

Myocardial stunning is associated with impaired calcium uptake by sarcoplasmic reticulum.

artículo científico publicado en 2009

N-terminus oligomerization regulates the function of cardiac ryanodine receptors

artículo científico publicado en 2013

Ouabain-induced contractures in mammalian heart muscle [proceedings]

artículo científico publicado en 1978

Patterns of interaction between anthraquinone drugs and the calcium-release channel from cardiac sarcoplasmic reticulum

scientific article published on 01 August 1990

Pharmacological regulators of intracellular calcium release channels.

artículo científico publicado en 2007

Phosphodiesterase inhibitors and the cardiac sarcoplasmic reticulum calcium release channel: differential effects of milrinone and enoximone.

artículo científico publicado en 1991

Probing luminal negative charge in the type 3 ryanodine receptor.

artículo científico publicado en 2005

Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium

scientific article published on 01 August 1980

Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid

artículo científico publicado en 2007

Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia

artículo científico publicado en 2016

Reactive oxygen species modify the structure and function of the cardiac sarcoplasmic reticulum calcium-release channel.

artículo científico publicado en 1991

Reconstitution of cardiac sarcoplasmic reticulum calcium channels

artículo científico publicado en 1989

Regulation of cardiac mitochondrial potassium-ion movements

scientific article published on 01 December 1980

Regulation of current flow through ryanodine receptors by luminal Ca2+.

artículo científico publicado en 1997

Regulation of the gating of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by luminal Ca2+.

artículo científico publicado en 1994

Relaxation in heart muscle: some morphological and biochemical considerations

artículo científico publicado el 1 de junio de 1978

Removal of clustered positive charge from dihydropyridine receptor II-III loop peptide augments activation of ryanodine receptors

artículo científico publicado en 2004

Residue Gln4863 within a predicted transmembrane sequence of the Ca2+ release channel (ryanodine receptor) is critical for ryanodine interaction

artículo científico publicado en 2003

Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate.

artículo científico publicado en 2001

Ryanodine receptor interaction with the SNARE-associated protein snapin

scientific journal article

Ryanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction.

scientific article published on 02 February 2010

Ryanodine receptor mutations in arrhythmias: advances in understanding the mechanisms of channel dysfunction.

artículo científico publicado en 2007

Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains.

artículo científico publicado en 2004

Ryanodine-induced structural alterations in the RyR channel suggested by neomycin block.

artículo científico publicado en 2002

Sarcolemmal calcium transport and drug action

artículo científico publicado en 1980

Separation of isolated cardiac sarcolemma into inside-out and right-side-out vesicles by affinity chromatography [proceedings]

artículo científico publicado en 1979

Sheep cardiac sarcoplasmic reticulum calcium-release channels: modification of conductance and gating by temperature

artículo científico publicado en 1991

Single channel recordings from human cardiac sarcoplasmic reticulum

artículo científico publicado en 1989

Solubilisation and reconstitution of the rabbit skeletal muscle sarcoplasmic reticulum K+ channel into liposomes suitable for patch clamp studies

artículo científico publicado en 1986

Stable expression and functional characterisation of the diamondback moth ryanodine receptor G4946E variant conferring resistance to diamide insecticides

artículo científico publicado en 2015

Structural components of ryanodine responsible for modulation of sarcoplasmic reticulum calcium channel function

artículo científico publicado en 1997

Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1.

artículo científico publicado en 2016

Sulmazole (AR-L 115BS) activates the sheep cardiac muscle sarcoplasmic reticulum calcium-release channel in the presence and absence of calcium

artículo científico publicado en 1990

Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level.

artículo científico

Temperature effects on the kinetics of calcium transport by cardiac mitochondria

artículo científico publicado en 1978

The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance

artículo científico publicado en 2005

The calcium-release channel from cardiac sarcoplasmic reticulum: function in the failing and acutely ischaemic heart.

artículo científico publicado en 1992

The cardiac ryanodine receptor (calcium release channel): emerging role in heart failure and arrhythmia pathogenesis.

artículo científico publicado en 2002

The characterization of a monovalent cation-selective channel of mammalian cardiac muscle sarcoplasmic reticulum

scientific article published on 01 January 1984

The gating of the sheep skeletal sarcoplasmic reticulum Ca(2+)-release channel is regulated by luminal Ca2+.

artículo científico publicado en 1995

The interaction of an impermeant cation with the sheep cardiac RyR channel alters ryanoid association

artículo científico publicado en 2006

The interaction of ryanoids with individual ryanodine receptor channels.

artículo científico publicado en 2004

The interactions of ATP, ADP, and inorganic phosphate with the sheep cardiac ryanodine receptor.

artículo científico publicado en 1998

The isolation and characterization of cardiac mitochondrial fractions from isoprenaline treated rats

artículo científico publicado en 1981

The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2.

artículo científico publicado en 2015

The ryanodine receptor pore: is there a consensus view?

artículo científico publicado en 2010

The therapeutic potential of new insights into myocardial excitation-contraction coupling.

artículo científico publicado en 2003

Triple mode of action of flecainide in catecholaminergic polymorphic ventricular tachycardia: reply.

artículo científico publicado en 2013

Two orientations of isolated cardiac sarcolemmal vesicles separated by affinity chromatography

artículo científico publicado en 1980

Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gating

artículo científico publicado en 2016

Using large organic cations to probe the nature of ryanodine modification in the sheep cardiac sarcoplasmic reticulum calcium release channel

artículo científico publicado en 1993

Voltage-sensitive equilibrium between two states within a ryanoid-modified conductance state of the ryanodine receptor channel

artículo científico publicado en 2005

Lista de obras de Alan J Williams

A Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes

A model for ionic conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum ⬇️

A model of the putative pore region of the cardiac ryanodine receptor channel

A novel and rapid approach to isolating functional ryanodine receptors

A possible molecular mechanism for 'stunning' of the myocardium.

A single isotope method for the measurement of the volume of the mitochondrial inner compartment

ATP-induced stimulation of calcium binding to cardiac sarcolemma ⬇️

Activation of the sheep cardiac Ca2+ release channel by simple heteroaromatics.

Activation of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by analogues of sulmazole.

Adenosine discriminates between the caffeine and adenine nucleotide sites on the sheep cardiac sarcoplasmic reticulum calcium-release channel

An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels

An assay for inorganic orthophosphate in the presence of alkaloids and related drugs

Asymmetric block of a monovalent cation-selective channel of rabbit cardiac sarcoplasmic reticulum by succinyl choline

Block of the ryanodine receptor channel by neomycin is relieved at high holding potentials

Block of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by tetra-alkyl ammonium cations

Calcium-proton exchange in cardiac and liver mitochondria ⬇️

Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain.

Cardiovascular receptors and calcium

Cation conduction in the calcium release channel of the cardiac sarcoplasmic reticulum under physiological and pathophysiological conditions.

Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.

Characterization of a Ca(2+)-dependent anion channel from sheep tracheal epithelium incorporated into planar bilayers.

Characterization of the ryanodine receptor-Ca2+ release channel from the thoracic tissues of the lepidopteran insect Heliothis virescens

Charged local anesthetics block ionic conduction in the sheep cardiac sarcoplasmic reticulum calcium release channel.

Chicken skeletal muscle ryanodine receptor isoforms: ion channel properties

Comparison of the protein constituents of sarcoplasmic reticulum isolated from rat skeletal and cardiac muscle.

Contamination of a cardiac sarcolemmal preparation with endothelial plasma membrane.

Cyclic ADP-ribose and related compounds activate sheep skeletal sarcoplasmic reticulum Ca2+ release channel

Cyclic ADP-ribose competes with ATP for the adenine nucleotide binding site on the cardiac ryanodine receptor Ca(2+)-release channel

Dantrolene rescues aberrant N-terminus intersubunit interactions in mutant pro-arrhythmic cardiac ryanodine receptors.

Digoxin activates sarcoplasmic reticulum Ca(2+)-release channels: a possible role in cardiac inotropy.

Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart.

Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum ⬇️

Do inactivation mechanisms rather than adaptation hold the key to understanding ryanodine receptor channel gating?

Effect of R56865 on cardiac sarcoplasmic reticulum function and its role as an antagonist of digoxin at the sarcoplasmic reticulum calcium release channel.

Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.

Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel

Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2)

Evidence for Ca(2+) activation and inactivation sites on the luminal side of the cardiac ryanodine receptor complex

Evidence for negative charge in the conduction pathway of the cardiac ryanodine receptor channel provided by the interaction of K+ channel N-type inactivation peptides

Evidence for novel caffeine and Ca2+ binding sites on the lobster skeletal ryanodine receptor

Excess noise in modified conductance states following the interaction of ryanoids with cardiac ryanodine receptor channels

Functional characterisation of the ryanodine receptor purified from sheep cardiac muscle sarcoplasmic reticulum

Functional characterization of the cardiac ryanodine receptor pore-forming region.

Gating of the native and purified cardiac SR Ca(2+)-release channel with monovalent cations as permeant species

Glycolytic pathway intermediates activate cardiac ryanodine receptors

How does ryanodine modify ion handling in the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel?

Hypoxia and calcium ⬇️

Insights into the gating mechanism of the ryanodine-modified human cardiac Ca2+-release channel (ryanodine receptor 2).

Ion conduction and discrimination in the sarcoplasmic reticulum ryanodine receptor/calcium-release channel

Ion conduction and selectivity in the ryanodine receptor channel

Large tetraalkyl ammonium cations produce a reduced conductance state in the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel ⬇️

Light at the end of the Ca(2+)-release channel tunnel: structures and mechanisms involved in ion translocation in ryanodine receptor channels

Markovian models of low and high activity levels of cardiac ryanodine receptors

Massive Accumulation of Myofibroblasts in the Critical Isthmus Is Associated With Ventricular Tachycardia Inducibility in Post-Infarct Swine Heart.

Measurement of ionic exchange in organelle suspensions with ion-selective electrodes [proceedings]

Measuring the length of the pore of the sheep cardiac sarcoplasmic reticulum calcium-release channel using related trimethylammonium ions as molecular calipers

Mechanisms of caffeine activation of single calcium-release channels of sheep cardiac sarcoplasmic reticulum

Modification of gating of an airway epithelial chloride channel by 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB)

Modification of the conductance and gating properties of ryanodine receptors by suramin.

Modification of the gating of the cardiac sarcoplasmic reticulum Ca(2+)-release channel by H2O2 and dithiothreitol.

Modulation of single Ca2+-dependent K+-channel activity by protein phosphorylation

Molecular cloning, characterisation and mRNA expression of the ryanodine receptor from the peach-potato aphid, Myzus persicae.

Monovalent cation conductance in the ryanodine receptor-channel of sheep cardiac muscle sarcoplasmic reticulum

Myocardial calcium signalling and arrhythmia pathogenesis.

Myocardial stunning is associated with impaired calcium uptake by sarcoplasmic reticulum.

N-terminus oligomerization regulates the function of cardiac ryanodine receptors

Ouabain-induced contractures in mammalian heart muscle [proceedings]

Patterns of interaction between anthraquinone drugs and the calcium-release channel from cardiac sarcoplasmic reticulum

Pharmacological regulators of intracellular calcium release channels.

Phosphodiesterase inhibitors and the cardiac sarcoplasmic reticulum calcium release channel: differential effects of milrinone and enoximone.

Probing luminal negative charge in the type 3 ryanodine receptor.

Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium

Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid

Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia

Reactive oxygen species modify the structure and function of the cardiac sarcoplasmic reticulum calcium-release channel.

Reconstitution of cardiac sarcoplasmic reticulum calcium channels

Regulation of cardiac mitochondrial potassium-ion movements

Regulation of current flow through ryanodine receptors by luminal Ca2+.

Regulation of the gating of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by luminal Ca2+.