Lista de obras - Philip Meuleman - Dominio Público Uruguay

101 HUMAN MONOCLONAL ANTIBODIES TARGETING SR-BI PREVENT HCV ENTRY AND VIRAL SPREAD IN VIVO

827 EXPERIMENTAL HCV VACCINE COMBINING ADENOVIRUS AND PROTEIN ELICITS POTENT T-CELL RESPONSES AND NEUTRALIZING ANTIBODIES IN RODENTS

article

861 THE LECTIN GRIFFITHSIN HAS ANTIVIRAL ACTIVITY AGAINST HEPATITIS C VIRUS IN VITRO AND IN VIVO

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

scientific article published on 13 February 2019

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

artículo científico publicado en 2014

A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo

artículo científico publicado en 2011

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

artículo científico publicado en 2017

A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice

artículo científico publicado en 2003

Absence of zoonotic hepatitis E virus infection in Flemish dairy cows

scientific article published on 09 May 2018

Animal Models for Hepatitis E virus

scientific article published on 18 June 2019

Animal Models to Study Hepatitis C Virus Infection.

artículo científico publicado en 2018

Animal models for the study of HCV

artículo científico publicado en 2015

Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model

artículo científico publicado en 2015

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

artículo científico publicado en 2015

Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication

artículo científico publicado en 2013

Assessment of Parasite Liver-Stage Burden in Human-Liver Chimeric Mice

artículo científico publicado en 2015

Blocking HCV entry as potential antiviral therapy

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections

scientific article published on 29 January 2020

Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant

artículo científico publicado en 2007

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

artículo científico publicado en 2006

Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models

artículo científico publicado en 2010

Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line

artículo científico publicado en 2016

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

artículo científico publicado en 2015

Combination of liquid-chromatography tandem mass spectrometry in different scan modes with human and chimeric mouse urine for the study of steroid metabolism

artículo científico publicado en 2009

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses

artículo científico publicado en 2014

Detection and characterization of a new metabolite of 17alpha-methyltestosterone

artículo científico publicado en 2009

Detection and structural investigation of metabolites of stanozolol in human urine by liquid chromatography tandem mass spectrometry

artículo científico publicado en 2009

Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A.

artículo científico publicado en 2011

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1.

artículo científico publicado en 2017

Development and validation of a quantitative gas chromatography-mass spectrometry method for the detection of endogenous androgens in mouse urine

artículo científico publicado en 2007

Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase

artículo científico publicado en 2011

Elucidating the differences in pathogenicity between hepatitis E virus genotypes: The quest continues.

artículo científico publicado en 2018

Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

artículo científico publicado en 2017

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

artículo científico publicado en 2016

Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes

artículo científico publicado en 2020

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

artículo científico publicado en 2010

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

artículo científico publicado en 2015

Functional Study of the C-Terminal Part of the Hepatitis C Virus E1 Ectodomain

scientific article published on 26 September 2018

G09 : Targeting a host-cell entry factor barricades antiviral resistant HCV variants from on-therapy breakthrough in human-liver mice

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

artículo científico publicado en 2014

Griffithsin has antiviral activity against hepatitis C virus

artículo científico publicado en 2011

HCV animal models and liver disease

artículo científico publicado en 2014

HCV animal models: a journey of more than 30 years

artículo científico publicado en 2009

HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice.

artículo científico publicado en 2015

Hepatitis C virus infection and related liver disease: the quest for the best animal model

artículo científico publicado en 2013

Hepatitis E Virus (HEV) Open Reading Frame 2 Antigen Kinetics in Human-Liver Chimeric Mice and Its Impact on HEV Diagnosis

scientific article published on 01 July 2019

Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein

artículo científico publicado en 2017

Hepatitis E virus in acute liver failure: An unusual suspect?

artículo científico publicado en 2016

Hepatitis E virus prevalence in Flemish blood donors

scientific article published on 24 July 2019

Host cell mTORC1 is required for HCV RNA replication

artículo científico publicado en 2015

Human but not mouse hepatocytes respond to interferon-lambda in vivo

artículo científico publicado en 2014

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection

artículo científico publicado en 2005

Human skin-derived precursor cells are poorly immunogenic and modulate the allogeneic immune response

artículo científico publicado en 2014

Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization

artículo científico publicado en 2010

Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus

artículo científico publicado en 2016

Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus

artículo científico publicado en 2006

Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine.

artículo científico publicado en 2018

Impact of lipids and lipoproteins on hepatitis C virus infection and virus neutralization

artículo científico publicado en 2014

In vitro and in vivo metabolisms of 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)

In vivo and in vitro metabolism of the synthetic cannabinoid JWH‐200 ⬇️

artículo científico publicado el 30 de septiembre de 2013

In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

artículo científico publicado en 2011

In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model

artículo científico publicado en 2001

Infectivity and stability of hepatitis C virus in different perfusion solutions

scientific article published on 12 July 2019

Is hepatitis E virus an emerging problem in industrialized countries?

artículo científico

Lipoprotein lipase inhibits hepatitis C virus (HCV) infection by blocking virus cell entry

artículo científico publicado en 2011

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

artículo científico publicado en 2020

Metabolic studies of prostanozol with the uPA-SCID chimeric mouse model and human liver microsomes

artículo científico publicado en 2016

Metabolic studies with promagnon, methylclostebol and methasterone in the uPA+/+-SCID chimeric mice

artículo científico publicado en 2011

Metabolism of methylstenbolone studied with human liver microsomes and the uPA⁺/⁺-SCID chimeric mouse model

artículo científico publicado en 2014

Methylene Blue Treatment of Grafts During Cold Ischemia Time Reduces the Risk of Hepatitis C Virus Transmission

scholarly article by Fabian A Helfritz et al published 20 October 2018 in Journal of Infectious Diseases

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

artículo científico publicado en 2013

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

artículo científico publicado en 2015

Mouse Systems to Model Hepatitis C Virus Treatment and Associated Resistance

artículo científico publicado en 2016

Murine IL-2 receptor beta chain blockade improves human leukocyte engraftment in SCID mice

artículo científico publicado en 1998

Murine tissues of human liver chimeric mice are not susceptible to HEV of genotype 1 and 3.

artículo científico publicado en 2017

New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle

artículo científico publicado en 2019

Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice.

artículo científico publicado en 2012

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

artículo científico publicado en 2022

O.053 The human liver uPA-SCID mouse, a preclinical model to test anti-hepatitis C compounds

article

O.055 The human liver-uPA-SCID mouse: a chimeric rodent model for the study of viral hepatitis

P0674 : Clinically approved T-type calcium channel inhibitors prevent hepatitis C virus (HCV) membrane fusion in a genotype-dependent manner

P0676 : Clearance of persistent hepatitis c virus infection using a monoclonal antibody specific for tight junction protein claudin-1

P131 STAT transcriptional activity is controlled by regulated deacetylation

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry

artículo científico publicado en 2017

Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain

artículo científico publicado en 2008

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action

artículo científico publicado en 2015

Prevention of hepatitis B infections: vaccination and its limitations

artículo científico publicado en 2001

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

artículo científico publicado en 2009

Robust hepatitis E virus infection and transcriptional response in human hepatocytes

scientific article published on 02 January 2020

Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication

artículo científico publicado en 2008

Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity

artículo científico publicado en 2007

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

artículo científico publicado en 2014

Steroid metabolism in chimeric mice with humanized liver

artículo científico publicado en 2009

Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver

artículo científico publicado en 2016

Successful Engraftment of Human Hepatocytes in uPA-SCID and FRG(®) KO Mice.

artículo científico publicado en 2017

Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents

artículo científico publicado en 2014

Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

artículo científico publicado en 2015

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

artículo científico publicado en 2012

The emergence of hepatitis E virus in Europe

The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry

artículo científico publicado en 2011

The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV.

artículo científico publicado en 2008

The interferon gamma secretion assay: a reliable tool to study interferon gamma production at the single cell level

artículo científico publicado en 2004

The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo

scholarly article by Daniel Todt published in September 2018

Thermostability of seven hepatitis C virus genotypes in vitro and in vivo

artículo científico publicado en 2013

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy.

artículo científico publicado en 2017

Transmission of hepatitis E virus infection to human-liver chimeric FRG mice using patient plasma

artículo científico publicado en 2017

Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.

artículo científico publicado en 2016

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

artículo científico publicado en 2014

Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse

artículo científico publicado en 2007

Updates in Hepatitis E virus (HEV) field; lessons learned from human liver chimeric mice

artículo científico publicado en 2019

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

artículo científico publicado en 2014

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation

artículo científico publicado en 2010

uPA+/+-SCID mouse with humanized liver as a model for in vivo metabolism of exogenous steroids: methandienone as a case study.

artículo científico publicado en 2009

Lista de obras de Philip Meuleman

101 HUMAN MONOCLONAL ANTIBODIES TARGETING SR-BI PREVENT HCV ENTRY AND VIRAL SPREAD IN VIVO

827 EXPERIMENTAL HCV VACCINE COMBINING ADENOVIRUS AND PROTEIN ELICITS POTENT T-CELL RESPONSES AND NEUTRALIZING ANTIBODIES IN RODENTS

861 THE LECTIN GRIFFITHSIN HAS ANTIVIRAL ACTIVITY AGAINST HEPATITIS C VIRUS IN VITRO AND IN VIVO

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice

Absence of zoonotic hepatitis E virus infection in Flemish dairy cows

Animal Models for Hepatitis E virus

Animal Models to Study Hepatitis C Virus Infection.

Animal models for the study of HCV

Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication

Assessment of Parasite Liver-Stage Burden in Human-Liver Chimeric Mice

Blocking HCV entry as potential antiviral therapy

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections

Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models

Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

Combination of liquid-chromatography tandem mass spectrometry in different scan modes with human and chimeric mouse urine for the study of steroid metabolism

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses

Detection and characterization of a new metabolite of 17alpha-methyltestosterone

Detection and structural investigation of metabolites of stanozolol in human urine by liquid chromatography tandem mass spectrometry

Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A.

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1.

Development and validation of a quantitative gas chromatography-mass spectrometry method for the detection of endogenous androgens in mouse urine

Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase

Elucidating the differences in pathogenicity between hepatitis E virus genotypes: The quest continues.

Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

Functional Study of the C-Terminal Part of the Hepatitis C Virus E1 Ectodomain

G09 : Targeting a host-cell entry factor barricades antiviral resistant HCV variants from on-therapy breakthrough in human-liver mice

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

Griffithsin has antiviral activity against hepatitis C virus

HCV animal models and liver disease

HCV animal models: a journey of more than 30 years

HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice.

Hepatitis C virus infection and related liver disease: the quest for the best animal model

Hepatitis E Virus (HEV) Open Reading Frame 2 Antigen Kinetics in Human-Liver Chimeric Mice and Its Impact on HEV Diagnosis

Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein

Hepatitis E virus in acute liver failure: An unusual suspect?

Hepatitis E virus prevalence in Flemish blood donors

Host cell mTORC1 is required for HCV RNA replication

Human but not mouse hepatocytes respond to interferon-lambda in vivo

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection

Human skin-derived precursor cells are poorly immunogenic and modulate the allogeneic immune response

Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization

Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus

Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus

Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine.

Impact of lipids and lipoproteins on hepatitis C virus infection and virus neutralization

In vitro and in vivo metabolisms of 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)

In vivo and in vitro metabolism of the synthetic cannabinoid JWH‐200 ⬇️

In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model

Infectivity and stability of hepatitis C virus in different perfusion solutions

Is hepatitis E virus an emerging problem in industrialized countries?

Lipoprotein lipase inhibits hepatitis C virus (HCV) infection by blocking virus cell entry

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

Metabolic studies of prostanozol with the uPA-SCID chimeric mouse model and human liver microsomes

Metabolic studies with promagnon, methylclostebol and methasterone in the uPA+/+-SCID chimeric mice

Metabolism of methylstenbolone studied with human liver microsomes and the uPA⁺/⁺-SCID chimeric mouse model

Methylene Blue Treatment of Grafts During Cold Ischemia Time Reduces the Risk of Hepatitis C Virus Transmission

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

Mouse Systems to Model Hepatitis C Virus Treatment and Associated Resistance

Murine IL-2 receptor beta chain blockade improves human leukocyte engraftment in SCID mice

Murine tissues of human liver chimeric mice are not susceptible to HEV of genotype 1 and 3.

New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle

Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice.

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

O.053 The human liver uPA-SCID mouse, a preclinical model to test anti-hepatitis C compounds