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Lista de obras de Jitka Poljaková

Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the ³²P-postlabeling technique.

artículo científico publicado en 2012

DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells

artículo científico publicado en 2007

DNA and histone deacetylases as targets for neuroblastoma treatment

artículo científico publicado en 2010

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2

artículo científico publicado el 1 de septiembre de 2008

Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5.

artículo científico publicado en 2012

Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells.

artículo científico publicado en 2009

Hypoxia-mediated histone acetylation and expression of N-myc transcription factor dictate aggressiveness of neuroblastoma cells

artículo científico publicado en 2014

Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those foundin vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine

artículo científico publicado en 2006

The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide

artículo científico publicado en 2004

The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells

artículo científico publicado en 2008

The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells.

artículo científico publicado en 2009

The synergistic effects of DNA-targeted chemotherapeutics and histone deacetylase inhibitors as therapeutic strategies for cancer treatment.

artículo científico publicado en 2012

Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells.

artículo científico publicado en 2015

Valproic acid overcomes hypoxia-induced resistance to apoptosis.

artículo científico publicado en 2011