Lista de obras - Emanuel Escher - Dominio Público Uruguay

A new method of iodine labelling of peptide hormones

artículo científico publicado en 1984

A novel procedure for daily measurements of hemodynamical, hematological, and biochemical parameters in conscious unrestrained rats

artículo científico publicado en 2000

A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling

artículo científico publicado en 2002

A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity

artículo científico publicado en 2010

A substance P antagonist not containing D-tryptophan

artículo científico publicado en 1984

Activation induces structural changes in the liganded angiotensin II type 1 receptor.

artículo científico publicado en 2009

Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method

artículo científico publicado en 2007

Agonists for the Chemokine Receptor CXCR4.

artículo científico publicado en 2011

An angiotensin II antagonist with strongly prolonged action

scientific article published on 01 May 1989

Analysis by substituted cysteine scanning mutagenesis of the fourth transmembrane domain of the CXCR4 receptor in its inactive and active state

artículo científico publicado en 2012

Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis

artículo científico publicado en 2009

Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form

artículo científico publicado en 2002

Angiotensin analogues palmitoylated in positions 1 and 4

scientific article published on 01 September 1997

Angiotensin-induced changes in the apparent size of rat liver angiotensin receptors

artículo científico publicado en 1984

Anti-angiotensin antibodies cross-reactive with nonpeptide angiotensin antagonists as angiotensin receptor model

artículo científico publicado en 1993

Apparent molecular weight of substance P/neurokinin-1 receptors determined using a photoaffinity labelled probe, [(3'-125I) D-Tyro, (4'-N3)Phe8, Nle11]-substance P.

artículo científico publicado en 1987

Ascorbic acid decreases the binding affinity of the AT1 receptor for angiotensin II.

artículo científico publicado en 2008

Biological properties and functional determinants of the urotensin II receptor.

artículo científico publicado en 2007

Biosensing based on surface plasmon resonance and living cells

artículo científico publicado en 2008

CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart

scientific journal article

Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity

artículo científico publicado en 2015

Characterization of a specific binding site for angiotensin II in chicken liver

scientific article published on 01 June 1997

Characterization of spinal actions of four substance P analogues

artículo científico publicado en 1985

Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket

artículo científico publicado en 2003

Critical Hydrogen Bond Formation for Activation of the Angiotensin II Type 1 Receptor ⬇️

artículo científico publicado el 7 de diciembre de 2012

Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay.

artículo científico publicado en 2005

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs

artículo científico publicado en 2012

Direct covalent attachment of small peptide antigens to enzyme-linked immunosorbent assay plates using radiation and carbodiimide activation

scientific article published on 01 October 1994

Effects of substance P analogues in the rat tail-flick test

scientific article published on 01 February 1987

Epitope tagging and immunoreactivity of the human angiotensin II type 1 receptor

artículo científico publicado en 1997

Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex

artículo científico publicado en 1988

Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy

scientific journal article

Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery.

artículo científico publicado en 2008

GPR103b functions in the peripheral regulation of adipogenesis.

artículo científico publicado en 2010

Human placental LHRH receptor: agonist and antagonist labeling produces differences in the size of the non-denatured, solubilized receptor

artículo científico publicado en 1988

Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.

artículo científico publicado en 2015

Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs

scientific article published on 01 March 1997

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

artículo científico publicado en 2014

Identification of transmembrane domain 3, 4 & 5 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

artículo científico publicado en 2013

Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor.

artículo científico publicado en 2009

Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.

artículo científico publicado en 1996

Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor

artículo científico publicado en 2005

Improved activity of a new angiotensin receptor antagonist by an injectable spray-dried polymer microsphere preparation

artículo científico publicado el 1 de julio de 1997

In vitro study of frog (Rana ridibunda Pallas) interrenal function by use of a simplified perifusion system

scientific article published on 01 June 1984

Influence of surface properties at biodegradable microsphere surfaces: effects on plasma protein adsorption and phagocytosis

artículo científico publicado en 1998

Inhibition of endothelin-converting enzyme for protection against neointimal proliferation following balloon angioplasty of the rat carotid artery

artículo científico publicado en 2002

Innocuity of agents for radiocontrast enhancement of urinary tract stones

scientific article published on 01 November 1995

Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.

artículo científico publicado en 2005

Isolation and structure analysis of a photoproduct of the new photoaffinity label p-nitrophenylalanine

artículo científico publicado el 9 de marzo de 1977

Low-energy (3-24 eV) electron damage to the peptide backbone

artículo científico publicado en 2007

Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction

artículo científico publicado en 2002

Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding

artículo científico publicado en 2000

Monitoring of MMPs activity in vivo, non-invasively, using solubility switchable MRI contrast agent

artículo científico publicado en 2009

Monitoring of native chemical ligation by surface plasmon resonance

artículo científico publicado en 2009

Monitoring of native chemical ligation on solid substrate by surface plasmon resonance.

artículo científico publicado en 2008

Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor

artículo científico publicado en 2008

N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor

artículo científico publicado en 1998

Neointima formation after vascular injury is angiotensin II mediated

artículo científico publicado en 1992

New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging

artículo científico publicado en 2009

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications

artículo científico publicado en 1996

Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model

artículo científico publicado en 2008

Partial agonists and antagonists for substance P.

artículo científico publicado en 1983

Partial agonists and antagonists for substance P.

artículo científico publicado en 1984

Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues.

artículo científico publicado en 2005

Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure

artículo científico publicado en 2000

Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain.

artículo científico publicado en 2003

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

artículo científico publicado en 2007

Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain ⬇️

artículo científico publicado el 13 de abril de 2010

Receptors for substance P. I. The pharmacological preparations

artículo científico publicado en 1984

Receptors for substance P. II. Classification by agonist fragments and homologues

scientific article published on 01 January 1984

Receptors for substance P. III. Classification by competitive antagonists

scientific article published on 01 January 1984

Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.

artículo científico publicado en 2002

Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor

artículo científico publicado en 2005

Role of calcium in stimulus-secretion coupling on isolated frog interrenal gland

scientific article published on 01 March 1986

S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II

artículo científico publicado en 2006

Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor

artículo científico publicado en 1993

Specific and irreversible block of the myotropic action of angiotensin II ⬇️

artículo científico publicado el 14 de septiembre de 1978

Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine selectivity

artículo científico publicado en 2006

Structure of the Human Angiotensin II Type 1 (AT1) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode ⬇️

artículo científico publicado el 5 de febrero de 2013

Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists

artículo científico publicado en 2016

Substance P antagonists active in vitro and in vivo

artículo científico publicado en 1982

Substance P antagonists showing some selectivity for different receptor types

artículo científico publicado en 1985

Substance P--structure-activity studies and the development of antagonists.

artículo científico publicado en 1984

Synthesis of an agonistic, difluoro-azido photolabel of angiotensin II and labeling of the AT1 receptor: transmembrane domains 3, 6, and 7 form the ligand-binding pocket

artículo científico publicado en 2006

Tachykinin antagonists: substitutions in positions 5 and 6 with amino acids from the primary sequence of substance P homologues

artículo científico publicado en 1985

Tachykinin receptors in smooth muscles: a study with agonists (substance P, neurokinin A) and antagonists.

artículo científico publicado en 1985

Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism

artículo científico publicado en 2010

Temperature-dependent variations of ligand-receptor contact points in hAT(1)

artículo científico publicado en 2007

The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: an MPA study on a constitutively active angiotensin II receptor mutant

artículo científico publicado en 2006

The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1.

artículo científico publicado en 2010

The angiotensin II binding site on Mycoplasma hyorhynis is structurally distinct from mammalian AT1 and AT2 receptors

artículo científico publicado en 1998

The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha

scientific article published on 13 August 2003

The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells.

artículo científico publicado en 2005

The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation

artículo científico publicado en 2009

The hydra head activator in human blood circulation. Degradation of the synthetic peptide by plasma angiotensin-converting enzyme

scientific article published on 01 August 1984

The neurogenic origin of hypertension in SHR may be mediated by angiotensin II through a receptor different from AT1 and AT2

artículo científico publicado en 1993

The second transmembrane domain of the human type 1 angiotensin II receptor participates in the formation of the ligand binding pocket and undergoes integral pivoting movement during the process of receptor activation

artículo científico publicado en 2009

Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea

artículo científico publicado en 1984

Use of LiCl in phospholipase C assays masks the impaired functionality of a mutant angiotensin II receptor

artículo científico publicado en 1997

Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide

artículo científico publicado en 1990

What can angiotensin antagonists do that converting-enzyme inhibition can't: the case of post-angioplastic restenosis

scientific article published on 01 July 1996

[Photoaffinity labelling of chymotrypsin. Synthesis of photorecognizable ligands]

artículo científico publicado en 1975

[The methionine proximity assay: an approach to glean receptor structures]

scientific article published on 01 December 2006

[The synthesis of 4'-azido-3',5'-ditritio-l-phenylalanine peptides as "photo-affinity probes" for ligand-receptor interaction (author's transl)]

scientific article published on 01 April 1976

beta 2-Inhibin contains the active core of human seminal plasma beta-inhibin: synthesis and bioactivity

artículo científico publicado en 1985

Lista de obras de Emanuel Escher

A new method of iodine labelling of peptide hormones

A novel procedure for daily measurements of hemodynamical, hematological, and biochemical parameters in conscious unrestrained rats

A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling

A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity

A substance P antagonist not containing D-tryptophan

Activation induces structural changes in the liganded angiotensin II type 1 receptor.

Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method

Agonists for the Chemokine Receptor CXCR4.

An angiotensin II antagonist with strongly prolonged action

Analysis by substituted cysteine scanning mutagenesis of the fourth transmembrane domain of the CXCR4 receptor in its inactive and active state

Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis

Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form

Angiotensin analogues palmitoylated in positions 1 and 4

Angiotensin-induced changes in the apparent size of rat liver angiotensin receptors

Anti-angiotensin antibodies cross-reactive with nonpeptide angiotensin antagonists as angiotensin receptor model

Apparent molecular weight of substance P/neurokinin-1 receptors determined using a photoaffinity labelled probe, [(3'-125I) D-Tyro, (4'-N3)Phe8, Nle11]-substance P.

Ascorbic acid decreases the binding affinity of the AT1 receptor for angiotensin II.

Biological properties and functional determinants of the urotensin II receptor.

Biosensing based on surface plasmon resonance and living cells

CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart

Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity

Characterization of a specific binding site for angiotensin II in chicken liver

Characterization of spinal actions of four substance P analogues

Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket

Critical Hydrogen Bond Formation for Activation of the Angiotensin II Type 1 Receptor ⬇️

Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay.

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs

Direct covalent attachment of small peptide antigens to enzyme-linked immunosorbent assay plates using radiation and carbodiimide activation

Effects of substance P analogues in the rat tail-flick test

Epitope tagging and immunoreactivity of the human angiotensin II type 1 receptor

Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex

Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy

Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery.

GPR103b functions in the peripheral regulation of adipogenesis.

Human placental LHRH receptor: agonist and antagonist labeling produces differences in the size of the non-denatured, solubilized receptor

Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.

Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

Identification of transmembrane domain 3, 4 & 5 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor.

Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.

Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor

Improved activity of a new angiotensin receptor antagonist by an injectable spray-dried polymer microsphere preparation

In vitro study of frog (Rana ridibunda Pallas) interrenal function by use of a simplified perifusion system

Influence of surface properties at biodegradable microsphere surfaces: effects on plasma protein adsorption and phagocytosis

Inhibition of endothelin-converting enzyme for protection against neointimal proliferation following balloon angioplasty of the rat carotid artery

Innocuity of agents for radiocontrast enhancement of urinary tract stones

Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.

Isolation and structure analysis of a photoproduct of the new photoaffinity label p-nitrophenylalanine

Low-energy (3-24 eV) electron damage to the peptide backbone

Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction

Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding

Monitoring of MMPs activity in vivo, non-invasively, using solubility switchable MRI contrast agent

Monitoring of native chemical ligation by surface plasmon resonance

Monitoring of native chemical ligation on solid substrate by surface plasmon resonance.

Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor

N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor

Neointima formation after vascular injury is angiotensin II mediated

New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications

Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model

Partial agonists and antagonists for substance P.

Partial agonists and antagonists for substance P.

Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues.

Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure

Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain.

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain ⬇️

Receptors for substance P. I. The pharmacological preparations

Receptors for substance P. II. Classification by agonist fragments and homologues

Receptors for substance P. III. Classification by competitive antagonists

Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.

Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor

Role of calcium in stimulus-secretion coupling on isolated frog interrenal gland

S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II

Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor

Specific and irreversible block of the myotropic action of angiotensin II ⬇️

Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine selectivity

Structure of the Human Angiotensin II Type 1 (AT1) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode ⬇️