Lista de obras - Thomas Jespersen - Dominio Público Uruguay

5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels

artículo científico publicado en 2004

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

artículo científico publicado en 2009

A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy.

artículo científico publicado en 2018

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

artículo científico publicado en 2011

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

artículo científico publicado en 2013

AMP-activated protein kinase downregulates Kv7.1 cell surface expression

artículo científico publicado en 2012

Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

artículo científico publicado en 2008

Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

scientific article published on 07 January 2019

An ERG channel inhibitor from the scorpion Buthus eupeus

artículo científico publicado en 2001

An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

artículo científico publicado en 2004

Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome

artículo científico publicado en 2008

Antiarrhythmic Effect of Either Negative Modulation or Blockade of Small Conductance Ca2+-activated K+ Channels on Ventricular Fibrillation in Guinea Pig Langendorff-perfused Heart

artículo científico publicado en 2015

Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses.

artículo científico publicado en 2017

Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

artículo científico publicado en 2015

Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses.

artículo científico publicado en 2014

Antiarrhythmic effect of IKr activation in a cellular model of LQT3.

artículo científico publicado en 2008

Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation.

artículo científico publicado en 2016

Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

scientific article published on 01 October 2019

Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

scientific article published on 01 December 2019

Attenuated Ventricular β-Adrenergic Response and Reduced Repolarization Reserve in a Rabbit Model of Chronic Heart Failure

article

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

artículo científico publicado en 2004

Biophysical characterization of KV3.1 potassium channel activating compounds

artículo científico publicado en 2015

Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

scientific article published on 01 October 2015

Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors

artículo científico publicado en 2007

Cardiac channelopathies and sudden infant death syndrome

artículo científico publicado en 2011

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

artículo científico publicado en 2006

Cardiovascular changes in childhood obesity ⬇️

artículo científico publicado en 2017

Characterization of cardiac repolarization in the Göttingen minipig

artículo científico publicado en 2010

Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current

artículo científico publicado en 2008

Characterization of two new dominant ClC-1 channel mutations associated with myotonia

artículo científico publicado en 2003

Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family.

artículo científico publicado en 2015

Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation

article published in 2015

Common and rare variants in SCN10A modulate the risk of atrial fibrillation

artículo científico publicado en 2015

Comparison of hemodynamics, cardiac electrophysiology, and ventricular arrhythmia in an open- and a closed-chest porcine model of acute myocardial infarction

artículo científico publicado en 2020

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

artículo científico publicado en 2011

Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

artículo científico publicado en 2012

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

artículo científico publicado en 2015

Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype

artículo científico publicado en 2004

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

artículo científico publicado en 2009

Does KCNE5 play a role in long QT syndrome?

artículo científico publicado en 2004

Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

artículo científico publicado en 2013

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

artículo científico publicado en 2002

Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation.

artículo científico publicado en 2017

Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

artículo científico publicado en 2010

Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation

artículo científico publicado en 2019

Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca 2+ -Activated K + Channel Inhibition

Efficient Non-PCR-Mediated Overlap Extension of PCR Fragments by Exonuclease “End Polishing” ⬇️

artículo científico publicado el 1 de julio de 1997

Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

artículo científico publicado en 2017

Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors.

artículo científico publicado en 1999

Flecainide Provocation Reveals Concealed Brugada Syndrome in a Long QT Syndrome Family With a Novel L1786Q Mutation in SCN5A

article

Functional testing of a bicistronic retroviral vector for intracellular peptide production

artículo científico publicado en 1999

Functionally selective AT(1) receptor activation reduces ischemia reperfusion injury

artículo científico publicado en 2012

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

artículo científico publicado en 2013

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology.

artículo científico publicado en 2013

High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

artículo científico publicado en 2012

Identification of a Kir3.4 mutation in congenital long QT syndrome

scientific journal article

Impact of arrhythmogenic calmodulin variants on small conductance Ca2+ -activated K+ (SK3) channels

scientific article published on 01 October 2019

Inherited cardiac diseases caused by Nav1.5 sodium channel mutations

scientific article published on 01 April 2009

Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel

scientific article published on 20 October 2009

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation

artículo científico publicado en 2018

Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

artículo científico publicado en 2010

Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

artículo científico publicado en 2014

KCNQ1 channels sense small changes in cell volume

artículo científico publicado en 2003

KCNQ4 channel activation by BMS-204352 and retigabine

artículo científico publicado en 2001

Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

artículo científico publicado en 2011

Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

artículo científico publicado en 2017

Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

artículo científico publicado en 2015

Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation

artículo científico publicado en 2019

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

artículo científico publicado en 2004

Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

artículo científico publicado en 2003

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

artículo científico publicado en 2011

Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

artículo científico publicado en 2018

PKC and AMPK regulation of Kv1.5 potassium channels

artículo científico publicado en 2015

Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia

artículo científico publicado en 2017

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.

artículo científico publicado en 2014

Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

artículo científico publicado en 2017

Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

artículo científico publicado en 2015

Pharmacological inhibition of IK1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

artículo científico publicado en 2016

Pharmacological modulation of SK3 channels.

artículo científico publicado en 2001

Pharmacological rescue of mutated Kv3.1 ion-channel linked to progressive myoclonus epilepsies

artículo científico publicado en 2018

Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

scholarly article by Jakob Dahl Nissen et al published August 2009 in Journal of Cardiovascular Pharmacology

Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

artículo científico publicado en 2017

Refractoriness in human atria: Time and voltage dependence of sodium channel availability.

artículo científico publicado en 2016

Regulation and physiological function of Nav1.5 and KCNQ1 channels ⬇️

artículo científico publicado el 1 de mayo de 2011

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases

artículo científico publicado en 2017

Screening of KCNN3 in patients with early-onset lone atrial fibrillation

Sick Sinus Syndrome, Progressive Cardiac Conduction Disease, Atrial Flutter and Ventricular Tachycardia Caused by a Novel SCN5A Mutation

article published in 2010

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

artículo científico publicado en 2014

Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

artículo científico publicado en 2003

Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

artículo científico publicado en 2017

Subtype-specific, bi-component inhibition of SK channels by low internal pH.

artículo científico publicado en 2006

Synergistic antiarrhythmic effect of combining inhibition of Ca²⁺-activated K⁺ (SK) channels and voltage-gated Na⁺ channels in an isolated heart model of atrial fibrillation

artículo científico publicado en 2014

Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

artículo científico publicado en 2017

The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity, and Cardiac Function in Zebrafish

artículo científico publicado en 2016

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

artículo científico publicado en 2007

The KCNQ1 potassium channel: from gene to physiological function

artículo científico publicado en 2005

The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes

scientific journal article

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

scientific article published on 19 June 2019

The Prevalence of Mutations inKCNQ1, KCNH2,andSCN5Ain an Unselected National Cohort of Young Sudden Unexplained Death Cases

article by BO GREGERS WINKEL et al published 6 August 2012 in Journal of Cardiovascular Electrophysiology

The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

artículo científico publicado en 2006

The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

artículo científico publicado en 2013

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

artículo científico publicado en 2017

Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses

scientific article published on 22 August 2018

Transgene stability for three replication-competent murine leukemia virus vectors

artículo científico publicado en 2004

Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

artículo científico publicado en 2009

Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis.

artículo científico publicado en 2017

Utility of left atrial strain for predicting atrial fibrillation following ischemic stroke

scientific article published on 26 April 2019

Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

artículo científico publicado en 2009

hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics

artículo científico publicado en 2005

Lista de obras de Thomas Jespersen

5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy.

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

AMP-activated protein kinase downregulates Kv7.1 cell surface expression

Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

An ERG channel inhibitor from the scorpion Buthus eupeus

An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome

Antiarrhythmic Effect of Either Negative Modulation or Blockade of Small Conductance Ca2+-activated K+ Channels on Ventricular Fibrillation in Guinea Pig Langendorff-perfused Heart

Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses.

Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses.

Antiarrhythmic effect of IKr activation in a cellular model of LQT3.

Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation.

Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

Attenuated Ventricular β-Adrenergic Response and Reduced Repolarization Reserve in a Rabbit Model of Chronic Heart Failure

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

Biophysical characterization of KV3.1 potassium channel activating compounds

Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors

Cardiac channelopathies and sudden infant death syndrome

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

Cardiovascular changes in childhood obesity ⬇️

Characterization of cardiac repolarization in the Göttingen minipig

Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current

Characterization of two new dominant ClC-1 channel mutations associated with myotonia

Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family.

Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation

Common and rare variants in SCN10A modulate the risk of atrial fibrillation

Comparison of hemodynamics, cardiac electrophysiology, and ventricular arrhythmia in an open- and a closed-chest porcine model of acute myocardial infarction

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

Does KCNE5 play a role in long QT syndrome?

Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation.

Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation

Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca 2+ -Activated K + Channel Inhibition

Efficient Non-PCR-Mediated Overlap Extension of PCR Fragments by Exonuclease “End Polishing” ⬇️

Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors.

Flecainide Provocation Reveals Concealed Brugada Syndrome in a Long QT Syndrome Family With a Novel L1786Q Mutation in SCN5A

Functional testing of a bicistronic retroviral vector for intracellular peptide production

Functionally selective AT(1) receptor activation reduces ischemia reperfusion injury

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology.

High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

Identification of a Kir3.4 mutation in congenital long QT syndrome

Impact of arrhythmogenic calmodulin variants on small conductance Ca2+ -activated K+ (SK3) channels

Inherited cardiac diseases caused by Nav1.5 sodium channel mutations

Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation

Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

KCNQ1 channels sense small changes in cell volume

KCNQ4 channel activation by BMS-204352 and retigabine

Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

PKC and AMPK regulation of Kv1.5 potassium channels

Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.

Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

Pharmacological inhibition of IK1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness