Lista de obras - Susan Cole - Dominio Público Uruguay

A monoclonal antibody detecting cell surface epitope on some drug resistant human tumour cell lines

artículo científico publicado en 1990

A new series of titanocene dichloride derivatives bearing chiral alkylammonium groups; assessment of their cytotoxic properties

A new series of titanocene dichloride derivatives bearing cyclic alkylammonium groups: Assessment of their cytotoxic properties

A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line

artículo científico publicado en 2003

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

artículo científico publicado en 2011

ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells

artículo científico publicado en 1999

Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites

artículo científico publicado en 2005

Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA

scientific journal article

Antibody production by human × human hybridomas in serum-free medium

artículo científico publicado en 1985

Applications of nanoparticle drug delivery systems for the reversal of multidrug resistance in cancer.

artículo científico publicado en 2016

Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23.

artículo científico publicado en 2016

Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).

artículo científico publicado en 2003

Biology of the multidrug resistance-associated protein, MRP.

artículo científico publicado en 1996

Bipartite nuclear localization signals in the C terminus of human topoisomerase II alpha.

artículo científico publicado en 1997

CFTR directly mediates nucleotide-regulated glutathione flux.

artículo científico publicado en 2003

Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line.

artículo científico publicado en 1994

Cellular toxicities of new titanocene dichloride derivatives containing pendant cyclic alkylammonium groups

article

Chalcogenopyrylium Compounds as Modulators of the ATP-Binding Cassette Transporters P-Glycoprotein (P-gp/ABCB1) and Multidrug Resistance Protein 1 (MRP1/ABCC1)

article

Chalcogenopyrylium dyes as differential modulators of organic anion transport by multidrug resistance protein 1 (MRP1), MRP2, and MRP4

artículo científico publicado en 2013

Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.

artículo científico publicado en 2001

Characterization of the human topoisomerase IIbeta (TOP2B) promoter activity: essential roles of the nuclear factor-Y (NF-Y)- and specificity protein-1 (Sp1)-binding sites.

artículo científico publicado en 2002

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

artículo científico publicado en 2002

Chemosensitivity testing of small cell lung cancer using the MTT assay.

artículo científico publicado en 1991

Clinical Significance of Multi-Drug Resistance Associated Protein and P-Glycoprotein in Patients with Bladder Cancer

artículo científico publicado en 1997

Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.

artículo científico publicado en 2003

Cloning, transfer, and characterization of multidrug resistance protein.

artículo científico publicado en 1998

Comparative phenotypic analysis of available human hybridoma fusion partners

artículo científico publicado en 1986

Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.

artículo científico publicado en 2000

Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4).

artículo científico publicado en 2016

Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications

artículo científico publicado en 1994

Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.

artículo científico publicado en 2002

Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter

artículo científico publicado en 2013

Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small-cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant ⬇️

artículo científico publicado el 1 de enero de 1991

Differential inhibition of hepatic ferrochelatase by the isomers of N-ethylprotoporphyrin IX

artículo científico publicado en 1981

Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.

artículo científico publicado en 2008

Drug-induced porphyrin biosynthesis--XIX. Potentiation of the porphyrin-inducing effects of SKF 525-A in the chick embryo liver by 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine, an antihibitor of ferrochelatase

artículo científico publicado en 1979

Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein

artículo científico publicado en 1989

Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line ⬇️

artículo científico publicado el 1 de abril de 1992

Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma

article

Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2.

artículo científico publicado en 2010

Expression of multidrug resistance protein gene in patients with glioma after chemotherapy.

artículo científico publicado en 1998

Ferrochelatase and N-alkylated porphyrins.

artículo científico publicado en 1984

Function, evolution and structure of multidrug resistance protein (MRP).

artículo científico publicado en 1997

Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).

artículo científico publicado en 2003

Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).

artículo científico publicado en 2005

Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1).

artículo científico publicado en 2005

Growth of human × human hybridomas in protein-free medium supplemented with ethanolamine

scientific article published on 01 February 1987

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).

artículo científico publicado en 2014

Human monoclonal antibodies.

artículo científico publicado en 1984

Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site

artículo científico publicado en 2001

Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta

artículo científico publicado en 2003

Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.

artículo científico publicado en 2001

Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

artículo científico publicado en 2004

Identification of regions required for apical membrane localization of human multidrug resistance protein 2.

artículo científico publicado en 2008

Inhibition of hepatic ferrochelatase by the four isomers of N-methylprotoporphyrin IX

artículo científico publicado en 1980

Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites

artículo científico publicado en 2005

Localization of a Substrate Specificity Domain in the Multidrug Resistance Protein

scientific article published in Journal of Biological Chemistry

MRP1 polymorphisms associated with citalopram response in patients with major depression

artículo científico publicado en 2010

Mammalian multidrug-resistance proteins (MRPs).

artículo científico

Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1).

artículo científico publicado en 2004

Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux

artículo científico publicado en 2012

Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.

artículo científico publicado en 2008

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

artículo científico publicado en 1997

Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).

artículo científico publicado en 2009

Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1)

scientific journal article

Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).

artículo científico

Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1).

artículo científico publicado en 2007

Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.

artículo científico publicado en 1999

Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy.

artículo científico publicado en 1998

Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.

artículo científico publicado en 1996

Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter

artículo científico publicado en 2014

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

artículo científico publicado en 2005

Multidrug resistance-associated antigens on drug-sensitive and -resistant human tumour cell lines.

artículo científico publicado en 1991

Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).

artículo científico publicado en 2008

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

artículo científico

Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function

artículo científico publicado en 2003

Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transp

artículo científico publicado en 2004

Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity.

artículo científico publicado en 2006

Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).

artículo científico publicado en 2004

N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity

artículo científico publicado en 2015

Non-P-glycoprotein-mediated multidrug-resistant human KB cells selected in medium containing adriamycin, cepharanthine, and mezerein.

artículo científico publicado en 1994

Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1

artículo científico publicado en 2007

Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions.

artículo científico publicado en 2016

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

scientific journal article

Rapid chemosensitivity testing of human lung tumor cells using the MTT assay

artículo científico publicado en 1986

Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells.

artículo científico publicado en 1996

Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1.

artículo científico publicado en 2008

Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia

artículo científico publicado en 1999

Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).

artículo científico publicado en 2003

Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.

artículo científico publicado en 2008

Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking

artículo científico publicado en 2005

Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas

artículo científico publicado en 2004

Sequence determinants of nuclear localization in the alpha and beta isoforms of human topoisomerase II.

artículo científico publicado en 1999

Specific immunoglobulin production and enhanced tumorigenicity following ascites growth of human hybridomas

artículo científico publicado en 1985

Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).

artículo científico publicado en 2008

Structural organization of the human TOP2A and TOP2B genes.

artículo científico publicado en 1998

Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1).

artículo científico publicado en 2003

Structural requirements in dihydropyridines for ferrochelatase inhibition and δ-aminolevulinic acid synthetase induction

artículo científico publicado en 1980

Structural, mechanistic and clinical aspects of MRP1.

artículo científico publicado en 1999

Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1.

artículo científico publicado en 2000

Subcellular localization analysis of the closely related Fps/Fes and Fer protein-tyrosine kinases suggests a distinct role for Fps/Fes in vesicular trafficking

artículo científico publicado en 2001

Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).

artículo científico publicado en 2005

Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future

artículo científico publicado en 2013

The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation

artículo científico publicado en 2004

Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.

artículo científico publicado en 2006

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

artículo científico publicado en 2001

Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1.

artículo científico publicado en 2004

Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

artículo científico publicado en 2006

Transport of glutathione and glutathione conjugates by MRP1.

artículo científico publicado en 2006

Tumourigenic multidrug-resistant HT1080 cells do not overexpress receptors for epidermal growth factor

artículo científico publicado en 1991

Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1.

artículo científico publicado en 2013

Two-dimensional electrophoretic display of restriction fragments from genomic DNA

artículo científico publicado en 1985

Use of the MTT assay for rapid determination of chemosensitivity of human leukemic blast cells

artículo científico publicado en 1988

[12] The EBV-hybridoma technique

artículo científico publicado en 1986

Lista de obras de Susan Cole

A monoclonal antibody detecting cell surface epitope on some drug resistant human tumour cell lines

A new series of titanocene dichloride derivatives bearing chiral alkylammonium groups; assessment of their cytotoxic properties

A new series of titanocene dichloride derivatives bearing cyclic alkylammonium groups: Assessment of their cytotoxic properties

A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells

Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites

Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA

Antibody production by human × human hybridomas in serum-free medium

Applications of nanoparticle drug delivery systems for the reversal of multidrug resistance in cancer.

Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23.

Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).

Biology of the multidrug resistance-associated protein, MRP.

Bipartite nuclear localization signals in the C terminus of human topoisomerase II alpha.

CFTR directly mediates nucleotide-regulated glutathione flux.

Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line.

Cellular toxicities of new titanocene dichloride derivatives containing pendant cyclic alkylammonium groups

Chalcogenopyrylium Compounds as Modulators of the ATP-Binding Cassette Transporters P-Glycoprotein (P-gp/ABCB1) and Multidrug Resistance Protein 1 (MRP1/ABCC1)

Chalcogenopyrylium dyes as differential modulators of organic anion transport by multidrug resistance protein 1 (MRP1), MRP2, and MRP4

Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.

Characterization of the human topoisomerase IIbeta (TOP2B) promoter activity: essential roles of the nuclear factor-Y (NF-Y)- and specificity protein-1 (Sp1)-binding sites.

Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

Chemosensitivity testing of small cell lung cancer using the MTT assay.

Clinical Significance of Multi-Drug Resistance Associated Protein and P-Glycoprotein in Patients with Bladder Cancer

Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.

Cloning, transfer, and characterization of multidrug resistance protein.

Comparative phenotypic analysis of available human hybridoma fusion partners

Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.

Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4).

Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications

Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.

Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter

Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small-cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant ⬇️

Differential inhibition of hepatic ferrochelatase by the isomers of N-ethylprotoporphyrin IX

Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.

Drug-induced porphyrin biosynthesis--XIX. Potentiation of the porphyrin-inducing effects of SKF 525-A in the chick embryo liver by 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine, an antihibitor of ferrochelatase

Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein

Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line ⬇️

Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma

Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2.

Expression of multidrug resistance protein gene in patients with glioma after chemotherapy.

Ferrochelatase and N-alkylated porphyrins.

Function, evolution and structure of multidrug resistance protein (MRP).

Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).

Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).

Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1).

Growth of human × human hybridomas in protein-free medium supplemented with ethanolamine

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).

Human monoclonal antibodies.

Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site

Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta

Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.

Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

Identification of regions required for apical membrane localization of human multidrug resistance protein 2.

Inhibition of hepatic ferrochelatase by the four isomers of N-methylprotoporphyrin IX

Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites

Localization of a Substrate Specificity Domain in the Multidrug Resistance Protein

MRP1 polymorphisms associated with citalopram response in patients with major depression

Mammalian multidrug-resistance proteins (MRPs).

Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1).

Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux

Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).

Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1)

Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).

Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1).

Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.

Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy.

Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.

Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

Multidrug resistance-associated antigens on drug-sensitive and -resistant human tumour cell lines.

Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function

Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transp

Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity.

Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).