Lista de obras - Gregory Fairn - Dominio Público Uruguay

7-Ketocholesterol Impairs Phagocytosis and Efferocytosis via Dysregulation of Phosphatidylinositol 4,5-bisphosphate

artículo científico publicado en 2018

A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway

artículo científico publicado en 2006

A weak base-generating system suitable for selective manipulation of lysosomal pH.

artículo científico publicado en 2011

Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference

artículo científico publicado en 2015

Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling

scientific article published on 03 May 2019

An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

scientific article published on 26 November 2018

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

artículo científico publicado en 2009

Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes

artículo científico publicado en 2013

Both the PH domain and N-terminal region of oxysterol-binding protein related protein 8S are required for localization to PM-ER contact sites

artículo científico publicado en 2018

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages

artículo científico publicado en 2013

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery

artículo científico publicado en 2019

CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor- and Complement Receptor 3-Dependent Mechanisms.

artículo científico publicado en 2016

Cell biology. A one-sided signal

artículo científico publicado en 2008

Cell biology. Precursor or charge supplier?

artículo científico publicado en 2012

Cleavage furrow organization requires PIP(2)-mediated recruitment of anillin.

artículo científico publicado en 2011

Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol'

artículo científico publicado en 2018

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol.

artículo científico publicado en 2015

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation.

artículo científico publicado en 2009

Cresyl violet: a superior fluorescent lysosomal marker

artículo científico publicado en 2016

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation

artículo científico publicado en 2013

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation

artículo científico publicado en 2014

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides

scientific article published on 20 June 2019

Emerging roles of the oxysterol-binding protein family in metabolism, transport, and signaling.

artículo científico publicado en 2008

Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P2 distribution and the localization of small G-proteins

artículo científico publicado en 2019

Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis

artículo científico publicado en 2016

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

artículo científico publicado en 2011

How nascent phagosomes mature to become phagolysosomes

artículo científico

Induction of spontaneous curvature and endocytosis: Unwanted consequences of cholesterol extraction using methyl-β-Cyclodextrin

artículo científico publicado en 2018

Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane.

artículo científico publicado en 2015

Integrity under stress: Host membrane remodelling and damage by fungal pathogens

scientific article published on 07 March 2019

Is basic science disappearing from medicine? The decline of biomedical research in the medical literature

artículo científico publicado en 2015

Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.

artículo científico publicado en 2013

Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

artículo científico publicado en 2017

Membrane metabolism mediated by Sec14 family members influences Arf GTPase activating protein activity for transport from the trans-Golgi

artículo científico publicado en 2005

Mesoscale organization of domains in the plasma membrane - beyond the lipid raft

artículo científico publicado en 2018

Molecular probes to visualize the location, organization and dynamics of lipids.

artículo científico publicado en 2014

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

artículo científico publicado en 2016

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

artículo científico publicado en 2018

PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells

artículo científico publicado en 2017

Palmitoylation of NOD1 and NOD2 is required for bacterial sensing

scientific article published on 24 October 2019

Perfringolysin O Theta Toxin as a Tool to Monitor the Distribution and Inhomogeneity of Cholesterol in Cellular Membranes

artículo científico publicado en 2016

Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling

scientific article published on 30 September 2019

Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes

artículo científico publicado en 2013

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

artículo científico publicado en 2017

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

scientific article published on 02 October 2011

Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins

artículo científico publicado en 2015

Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.

artículo científico publicado en 2009

Rapamycin-based inducible translocation systems for studying phagocytosis.

artículo científico publicado en 2011

Regulation of phosphoinositide levels by the phospholipid transfer protein Sec14p controls Cdc42p/p21-activated kinase-mediated cell cycle progression at cytokinesis

artículo científico publicado en 2007

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine

artículo científico publicado en 2016

Studying phospholipid metabolism using yeast systematic and chemical genetics

artículo científico publicado en 2005

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.

artículo científico publicado en 2016

The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.

artículo científico publicado en 2007

The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport

artículo científico publicado en 2005

The yeast oxysterol binding protein Kes1 maintains sphingolipid levels

artículo científico publicado en 2013

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

artículo científico publicado en 2017

Lista de obras de Gregory Fairn

7-Ketocholesterol Impairs Phagocytosis and Efferocytosis via Dysregulation of Phosphatidylinositol 4,5-bisphosphate

A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway

A weak base-generating system suitable for selective manipulation of lysosomal pH.

Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference

Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling

An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes

Both the PH domain and N-terminal region of oxysterol-binding protein related protein 8S are required for localization to PM-ER contact sites

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery

CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor- and Complement Receptor 3-Dependent Mechanisms.

Cell biology. A one-sided signal

Cell biology. Precursor or charge supplier?

Cleavage furrow organization requires PIP(2)-mediated recruitment of anillin.

Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol'

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol.

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation.

Cresyl violet: a superior fluorescent lysosomal marker

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides

Emerging roles of the oxysterol-binding protein family in metabolism, transport, and signaling.

Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P2 distribution and the localization of small G-proteins

Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

How nascent phagosomes mature to become phagolysosomes

Induction of spontaneous curvature and endocytosis: Unwanted consequences of cholesterol extraction using methyl-β-Cyclodextrin

Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane.

Integrity under stress: Host membrane remodelling and damage by fungal pathogens

Is basic science disappearing from medicine? The decline of biomedical research in the medical literature

Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.

Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

Membrane metabolism mediated by Sec14 family members influences Arf GTPase activating protein activity for transport from the trans-Golgi

Mesoscale organization of domains in the plasma membrane - beyond the lipid raft

Molecular probes to visualize the location, organization and dynamics of lipids.

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells

Palmitoylation of NOD1 and NOD2 is required for bacterial sensing

Perfringolysin O Theta Toxin as a Tool to Monitor the Distribution and Inhomogeneity of Cholesterol in Cellular Membranes

Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling

Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins

Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.

Rapamycin-based inducible translocation systems for studying phagocytosis.

Regulation of phosphoinositide levels by the phospholipid transfer protein Sec14p controls Cdc42p/p21-activated kinase-mediated cell cycle progression at cytokinesis

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine

Studying phospholipid metabolism using yeast systematic and chemical genetics

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.

The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.

The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport

The yeast oxysterol binding protein Kes1 maintains sphingolipid levels

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis