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Lista de obras de Barbara Bierer

2475 The leveling of clinical research competencies

A Framework for Ethical Payment to Research Participants

scholarly article

A Global, Neutral Platform for Sharing Trial Data

artículo científico publicado en 2016

A Study of Induced Hyponatremia in the Prevention and Treatment of Sickle-Cell Crisis

article

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen

artículo científico publicado en 1992

A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center

artículo científico publicado en 2014

A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.

artículo científico publicado en 1989

A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins

scientific article published on 01 April 1989

A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation

artículo científico publicado en 2001

A role for calcineurin in degranulation of murine cytotoxic T lymphocytes ⬇️

artículo científico publicado el 1 de abril de 1993

Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

artículo científico publicado en 1986

Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation.

artículo científico publicado en 1999

Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation

artículo científico publicado en 1994

Adhesion receptors in lymphocyte activation.

artículo científico publicado en 1994

Aggregating data from COVID-19 trials

scientific article published on 01 June 2020

Analysis of CD4 and CD2 receptor function

artículo científico publicado en 1988

Animal Models for Tumor Immunology

scholarly article published August 2008

Assessment of a shortened informed consent form for pediatric research: a pilot study

article published in 2018

Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.

artículo científico publicado en 1998

Biomedical innovation in academic institutions: mitigating conflict of interest

artículo científico publicado en 2011

Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia ⬇️

artículo científico publicado el 1 de noviembre de 1997

Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda

artículo científico publicado en 2017

CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells

artículo científico publicado en 2003

CD4, CD8 and CD2 in T cell adhesion and signaling.

artículo científico publicado en 1993

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1 ⬇️

artículo científico publicado el 21 de noviembre de 1991

CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28

artículo científico publicado en 1999

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A ⬇️

artículo científico publicado el 1 de mayo de 1992

Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin

artículo científico publicado en 2002

Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin

scholarly article by Ta-Kai Li published in January 2002

Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.

artículo científico publicado en 1992

Characterization of Informed Consent Forms Posted on ClinicalTrials.gov

artículo científico publicado en 2021

Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells

artículo científico publicado en 1995

Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes

artículo científico publicado en 2003

Committing to the Inclusion of Diverse Populations in Clinical Research

scientific article published on 02 January 2020

Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.

artículo científico publicado en 1996

Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule

artículo científico publicado en 2016

Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas

artículo científico publicado en 1992

Credit data generators for data reuse

artículo científico publicado en 2019

Cross-linking CD28 leads to activation of 70-kDa S6 kinase

artículo científico publicado en 1994

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.

artículo científico publicado en 1993

Data Authorship as an Incentive to Data Sharing

artículo científico publicado en 2017

Data Authorship as an Incentive to Data Sharing

article by Barbara Bierer et al published 27 July 2017 in The New England Journal of Medicine

Development of a plain-language library of educational resources for research participants

scientific article published on 01 February 2018

Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression

artículo científico publicado en 2002

Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling

artículo científico publicado en 2002

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

artículo científico publicado en 1994

Disruptive and avoidable: GDPR challenges to secondary research uses of data

artículo científico publicado en 2020

EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability

artículo científico publicado en 2000

Economic vulnerability and payment for research participation

artículo científico publicado en 2020

Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12 ⬇️

artículo científico publicado el 15 de septiembre de 1992

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome

artículo científico publicado en 1991

Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation

artículo científico publicado en 2009

Ethical Challenges in Clinical Research During the COVID-19 Pandemic

artículo científico publicado en 2020

Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism

artículo científico publicado en 2005

Expression and function of a CD 5 cDNA in human and murine T cells

article

Expression of CD5 regulates responsiveness to IL-1.

artículo científico publicado en 1988

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation

artículo científico publicado en 1988

FK 506 and rapamycin: molecular probes of T-lymphocyte activation

artículo científico publicado el 1 de diciembre de 1991

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells

artículo científico publicado en 1995

Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use

scientific article published on 26 February 2020

Forensic bitemark identification: weak foundations, exaggerated claims

artículo científico publicado en 2016

Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3 ⬇️

artículo científico publicado el 15 de febrero de 1990

Functional analysis of CD2, CD4, and CD8 in T-cell activation

artículo científico publicado en 1988

Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells

artículo científico publicado en 2006

Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines ⬇️

artículo científico publicado el 1 de enero de 1998

Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers

artículo científico publicado en 2014

How to fix the GDPR's frustration of global biomedical research

scientific article published on 01 October 2020

Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation

artículo científico publicado en 1995

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

scientific journal article

Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis

artículo científico publicado en 2001

Immunophilins in protein folding and immunosuppression.

artículo científico publicado en 1994

Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees

artículo científico publicado en 2016

Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support

artículo científico publicado en 2003

Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A

scientific article published on 01 December 1994

Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement

artículo científico publicado en 2020

Institutions as an ethical locus of research prioritisation

Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes ⬇️

artículo científico publicado el 1 de julio de 1991

Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation

artículo científico publicado en 1988

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin ⬇️

artículo científico publicado el 15 de agosto de 1992

Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation ⬇️

artículo científico publicado el 1 de febrero de 1995

Isolation and Differentiation of Stem and Progenitor Cells

Isolation and Differentiation of Stem and Progenitor Cells

artículo científico publicado en 2005

Issues in the registration of database studies

artículo científico publicado en 2020

Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density

artículo científico publicado en 1987

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals

article

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals

scientific article published on 06 January 2020

Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum

artículo científico publicado en 1993

Measurement of Calcineurin Phosphatase Activity in Cell Extracts

artículo científico publicado en 1996

Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction

artículo científico publicado el 1 de junio de 1990

Molecular and biological actions of cyclosporin A and FK506 on T cell development and function

artículo científico publicado en 1994

Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25 ⬇️

artículo científico publicado el 5 de junio de 1992

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

artículo científico publicado en 1991

Navigating the ethics of remote research data collection

artículo científico publicado en 2021

Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations".

artículo científico publicado en 2017

On Scarcity and the Value of Clinical Trials.

artículo científico publicado en 2018

Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction

artículo científico publicado en 1990

Patient-reported safety and quality of care in outpatient oncology

artículo científico publicado en 2007

Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.

artículo científico publicado en 1988

Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor

artículo científico publicado en 1995

Physician self-assessment of leadership skills

Preface

Preface

Preparing for Responsible Sharing of Clinical Trial Data

artículo científico publicado en 2013

Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov

scientific article published on 18 February 2020

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand ⬇️

artículo científico publicado el 26 de octubre de 1990

Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research

scientific article published on 12 July 2019

Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule

artículo científico publicado en 2017

Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.

artículo científico publicado en 1983

Raising standards for global data-sharing-Response

artículo científico publicado en 2021

Rapamycin and FK506 binding proteins (immunophilins)

article

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

artículo científico publicado el 14 de agosto de 1992

Rapamycin: Biological and therapeutic effects, binding by immunophilins and molecular targets of action

Recent advances in immunosuppression

Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin

artículo científico publicado en 2003

Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.

artículo científico publicado en 1988

Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India

article

Reimagining Health Data Exchange: An Application Programming Interface�Enabled Roadmap for India (Preprint)

Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations

artículo científico publicado en 2019

Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity

artículo científico publicado en 2019

Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems

artículo científico publicado en 2014

Responsibilities of Data Monitoring Committees: Consensus Recommendations

artículo científico publicado en 2016

Rethinking ethical oversight in the era of the learning health system

scientific article published on 25 August 2020

Returning aggregate results of clinical trials: Empirical data of patient preferences

artículo científico publicado en 2018

Revised 'Common Rule' Shapes Protections For Research Participants.

artículo científico publicado en 2017

Scientific Merit Predicates Ethical Review of Clinical Research

scientific article published on 01 May 2019

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies

artículo científico publicado en 1991

Sharing and reuse of individual participant data from clinical trials: principles and recommendations.

artículo científico publicado en 2017

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation

artículo científico publicado en 1987

Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58 ⬇️

artículo científico publicado el 1 de abril de 1993

Social Media as an Ethical Tool for Retention in Clinical Trials

artículo científico publicado en 2019

Standards for Clinical Research: Keeping Pace With the Technology of the Future

artículo científico publicado en 2016

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

artículo científico publicado en 1993

Suppression of human IL-1β, IL-2, IFN-γ, and TNF-α production by cigarette smoke extracts

article

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor

artículo científico publicado en 1988

T cell adhesion molecules

artículo científico publicado en 1988

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.

artículo científico publicado en 1993

T cell receptor activation of a ribosomal S6 kinase activity

artículo científico publicado en 1992

T cell receptors: adhesion and signaling

artículo científico publicado en 1991

T cell regulation of p62(dok) (Dok1) association with Crk-L

artículo científico publicado en 2001

T cell signal transduction and the role of CD7 in costimulation

artículo científico publicado en 2001

T-lymphocyte activation: the biology and function of CD2 and CD4.

artículo científico publicado en 1989

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes

artículo científico publicado en 1987

The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain

artículo científico publicado en 1999

The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education

artículo científico

The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight

artículo científico publicado en 2014

The PubPeer conundrum: Administrative challenges in research misconduct proceedings

The Revised and Final Common Rule: An Unfinished Story

scientific article published on 01 November 2017

The SMART IRB platform: A national resource for IRB review for multisite studies

scientific article published on 29 July 2019

The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules

artículo científico publicado en 1998

The biologic roles of CD2, CD4, and CD8 in T-cell activation

artículo científico

The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines.

artículo científico publicado en 1993

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

artículo científico publicado en 1995

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

artículo científico publicado en 1991

The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses

article

The role of functional cell surface antigens in T cell activation

artículo científico publicado en 1986

Time for NIH to lead on data sharing

artículo científico publicado en 2020

Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance

scientific article published on 13 March 2019

Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials

scientific article published on 08 April 2018

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

artículo científico publicado en 1990

Universal Funder Responsibilities That Advance Social Value

scientific article published on 01 November 2018

Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens

artículo científico publicado en 2017

Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element

artículo científico publicado en 2002

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations

artículo científico publicado en 2017

Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma

artículo científico publicado en 2017

What do revised U.S. rules mean for human research?

artículo científico publicado en 2017

When clinical trials compete: prioritising study recruitment

artículo científico publicado en 2017

Yeast Bim1p promotes the G1-specific dynamics of microtubules.

artículo científico publicado en 1999

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