Lista de obras - Heinz Jacobs - Dominio Público Uruguay

AID splice variants lack deaminase activity.

artículo científico publicado en 2009

Bcl-2 reduces lymphomagenesis in deltaV-TCRbeta transgenic mice

artículo científico publicado en 1997

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

artículo científico publicado en 1994

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma

scientific article published on 17 June 2019

Constitutive expression of the pre-TCR enables development of mature T cells.

artículo científico publicado en 2006

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

article

DNA damage tolerance in hematopoietic stem and progenitor cells in mice

artículo científico publicado en 2017

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

artículo científico publicado en 2002

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

artículo científico publicado en 2009

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

artículo científico publicado en 2013

Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

artículo científico publicado en 2014

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway

artículo científico publicado en 2013

Gimap4 accelerates T-cell death.

artículo científico publicado en 2006

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase

artículo científico publicado en 2011

Heterogeneous differentiation patterns of individual CD8+ T cells.

artículo científico publicado en 2013

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation

artículo científico publicado en 2021

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

scientific journal article

Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.

artículo científico publicado en 2011

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

artículo científico publicado en 2009

Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells

artículo científico publicado en 1990

Neutrophil myeloperoxidase activity and the influence of two single-nucleotide promoter polymorphisms

artículo científico publicado en 2003

Overexpression of the FosB2 gene in thymocytes causes aberrant development of T cells and thymic epithelial cells

scientific article published on 01 March 1997

Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis

artículo científico publicado en 2010

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.

artículo científico publicado en 2011

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

artículo científico publicado en 2011

PIM1 reconstitutes thymus cellularity in interleukin 7- and common gamma chain-mutant mice and permits thymocyte maturation in Rag- but not CD3gamma-deficient mice

artículo científico publicado en 1999

Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger

article

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis

artículo científico publicado en 2016

Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production

artículo científico publicado en 2011

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.

artículo científico publicado en 2005

Reassessing genomic targeting of AID

artículo científico publicado en 2012

Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.

artículo científico publicado en 2013

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage

artículo científico publicado en 2014

Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis

artículo científico publicado en 2014

Somatic hypermutation in the heavy chain locus correlates with transcription

artículo científico publicado en 1998

Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

artículo científico publicado en 1996

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice.

artículo científico publicado en 2009

T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert.

artículo científico publicado en 2014

TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function.

artículo científico publicado en 2000

Temporally distinct translesion synthesis pathways for ultraviolet light-induced photoproducts in the mammalian genome.

artículo científico publicado en 2012

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

artículo científico publicado en 2005

The Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination.

artículo científico publicado en 2010

The Ig heavy chain protein but not its message controls early B cell development

scientific article published on 23 November 2020

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells

artículo científico publicado en 2020

The primary structure of a feline class I gene: striking similarity to HLA-A.

artículo científico publicado en 1989

The truncated estrogen receptor alpha variant lacking exon 5 is not involved in progesterone receptor expression in meningiomas

artículo científico publicado en 1999

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.

artículo científico publicado en 2014

Towards an understanding of C9orf82 protein/CAAP1 function

artículo científico publicado en 2019

Lista de obras de Heinz Jacobs

AID splice variants lack deaminase activity.

Bcl-2 reduces lymphomagenesis in deltaV-TCRbeta transgenic mice

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma

Constitutive expression of the pre-TCR enables development of mature T cells.

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

DNA damage tolerance in hematopoietic stem and progenitor cells in mice

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway

Gimap4 accelerates T-cell death.

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase

Heterogeneous differentiation patterns of individual CD8+ T cells.

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells

Neutrophil myeloperoxidase activity and the influence of two single-nucleotide promoter polymorphisms

Overexpression of the FosB2 gene in thymocytes causes aberrant development of T cells and thymic epithelial cells

Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

PIM1 reconstitutes thymus cellularity in interleukin 7- and common gamma chain-mutant mice and permits thymocyte maturation in Rag- but not CD3gamma-deficient mice

Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis

Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.

Reassessing genomic targeting of AID

Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage

Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis

Somatic hypermutation in the heavy chain locus correlates with transcription

Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice.

T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert.

TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function.

Temporally distinct translesion synthesis pathways for ultraviolet light-induced photoproducts in the mammalian genome.

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

The Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination.

The Ig heavy chain protein but not its message controls early B cell development

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells

The primary structure of a feline class I gene: striking similarity to HLA-A.

The truncated estrogen receptor alpha variant lacking exon 5 is not involved in progesterone receptor expression in meningiomas

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.

Towards an understanding of C9orf82 protein/CAAP1 function