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Lista de obras de Susan Clark

A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation

artículo científico publicado en 2019

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer.

artículo científico publicado en 2013

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning

artículo científico publicado en 2009

Abstract A4: Whole genome sequencing of free circulating DNA from plasma of HGSOC patients

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.

artículo científico publicado en 2017

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

artículo científico publicado en 2011

Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis

artículo científico publicado en 2007

Advances in Prognostic Methylation Biomarkers for Prostate Cancer

artículo científico publicado en 2020

Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome.

artículo científico publicado en 2017

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

scientific article published on 18 March 2020

Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts.

artículo científico publicado en 2004

BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer

artículo científico publicado en 2013

BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells

BayMeth: improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach

artículo científico publicado en 2014

Benchmark study comparing liftover tools for genome conversion of epigenome sequencing data

artículo científico publicado en 2020

Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA

artículo científico publicado en 2012

Bisulphite Sequencing of Chromatin Immunoprecipitated DNA (BisChIP-seq).

artículo científico publicado en 2018

COBRA-Seq: Sensitive and Quantitative Methylome Profiling

artículo científico publicado en 2015

Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

artículo científico publicado en 2021

Cancer-specific region of hypermethylation identified within the HIC1 putative tumour suppressor gene in acute myeloid leukaemia

artículo científico publicado en 1999

Chromatin remodeler mutations in human cancers: epigenetic implications

artículo científico publicado en 2014

Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer

artículo científico publicado en 2014

Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

artículo científico publicado en 2010

Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias

artículo científico publicado en 2011

Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA.

artículo científico publicado en 2017

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

artículo científico publicado en 2020

Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

artículo científico publicado en 2007

Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity

artículo científico publicado en 2010

Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains

scientific article published on 07 January 2020

Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.

artículo científico publicado en 2015

Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.

artículo científico publicado en 2011

Copy-number-aware differential analysis of quantitative DNA sequencing data

artículo científico publicado en 2012

CpNpG methylation in mammalian cells ⬇️

artículo científico publicado el 1 de mayo de 1995

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling.

artículo científico publicado en 2016

Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts.

artículo científico publicado en 1998

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

scientific article published on 01 February 2019

DNA methylation analysis in mammalian cells

artículo científico publicado en 2002

DNA methylation and gene silencing in cancer: which is the guilty party?

artículo científico publicado en 2002

DNA methylation changes in leukaemia

artículo científico publicado en 2002

DNA methylation changes in ovarian cancer: implications for early diagnosis, prognosis and treatment

artículo científico publicado en 2008

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer.

artículo científico publicado en 2015

DNA methylation profile of triple negative breast cancer-specific genes comparing lymph node positive patients to lymph node negative patients

artículo científico publicado en 2016

DNA methylation: Bisulphite modification and analysis

artículo científico publicado en 2006

DNA methylation: bisulphite modification and analysis.

artículo científico publicado en 2011

De novo identification of differentially methylated regions in the human genome.

artículo científico publicado en 2015

Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA.

artículo científico publicado en 1997

Development and protective efficacy of a recombinant-DNA derived fimbrial vaccine against enterotoxic colibacillosis in neonatal piglets.

artículo científico publicado en 1988

Direct Cloning of Polymerase Chain Reaction Products in an Xcml T-Vector

artículo científico publicado en 1994

Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription

artículo científico publicado en 2011

Disruption of the 3D cancer genome blueprint.

artículo científico publicado en 2016

Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells

artículo científico publicado en 2011

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

artículo científico publicado en 2015

ELF5 modulates the estrogen receptor cistrome in breast cancer

artículo científico publicado en 2020

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

artículo científico publicado en 2012

Enduring epigenetic landmarks define the cancer microenvironment.

artículo científico publicado en 2018

Epigenetic architecture and miRNA: reciprocal regulators.

artículo científico publicado en 2010

Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers.

artículo científico publicado en 2010

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

artículo científico publicado en 2007

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

artículo científico publicado en 2006

Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer

artículo científico publicado en 2020

Epigenome remodelling in breast cancer: insights from an early in vitro model of carcinogenesis

artículo científico publicado en 2012

Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation

artículo científico publicado en 2010

Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements

scientific article published on 01 February 2019

Exploring and exploiting the aberrant DNA methylation profile of endocrine-resistant breast cancer

artículo científico publicado en 2013

GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association

artículo científico publicado en 2013

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

artículo científico publicado en 2016

Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value

artículo científico publicado en 2015

Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines

artículo científico publicado en 2014

Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements

artículo científico publicado en 2007

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

artículo científico publicado en 2018

H2A.Z acetylation and transcription: ready, steady, go!

scientific article published on 18 April 2016

Human histone genes are interspersed with members of the Alu family and with other transcribed sequences

article

Hypermethylation of the Inhibin -Subunit Gene in Prostate Carcinoma

article

Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy

artículo científico publicado en 2005

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

artículo científico publicado en 2002

Identification and resolution of artifacts in bisulfite sequencing.

artículo científico publicado en 2002

Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer

artículo científico publicado en 2021

Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins

artículo científico publicado en 2011

Increased DNA methyltransferase expression in leukaemia

scientific article published on 01 March 1998

Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups

artículo científico publicado en 2019

Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers

artículo científico publicado en 2011

Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

artículo científico publicado en 2011

Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease.

artículo científico publicado en 2009

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer

artículo científico publicado en 2016

Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours.

artículo científico

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status i

artículo científico publicado en 2012

MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection

artículo científico publicado en 2020

Methyl-CpG-binding domain proteins: readers of the epigenome

artículo científico publicado en 2015

Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer

artículo científico publicado en 2014

Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma

artículo científico publicado en 2014

Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes

scientific article published on 02 July 2019

Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.

artículo científico

MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma.

artículo científico publicado en 2011

MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene

artículo científico publicado en 2015

Mining cancer methylomes: prospects and challenges

artículo científico publicado en 2013

Monozygotic twins and triplets discordant for amyotrophic lateral sclerosis display differential methylation and gene expression.

artículo científico publicado en 2019

Multiple H4 histone mRNAs of HeLa cells are encoded in different genes

artículo científico publicado en 1982

Multiplex bisulfite PCR resequencing of clinical FFPE DNA.

artículo científico publicado en 2015

Mutation and methylation analysis of TP53 in adrenal carcinogenesis.

artículo científico publicado en 2005

NGSANE: a lightweight production informatics framework for high-throughput data analysis.

artículo científico publicado en 2014

Nucleotide-Level Profiling of m5C RNA Methylation

artículo científico publicado en 2016

Organization of human histone genes ⬇️

artículo científico publicado el 1 de marzo de 1982

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

artículo científico publicado en 2006

Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.

artículo científico publicado en 2014

Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer.

artículo científico publicado en 2011

Prostate cancer epigenetic biomarkers: next-generation technologies.

artículo científico

Protocol matters: which methylome are you actually studying?

artículo científico publicado en 2010

Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer

artículo científico publicado en 2014

Regional activation of the cancer genome by long-range epigenetic remodeling

artículo científico publicado en 2012

Repitools: an R package for the analysis of enrichment-based epigenomic data

artículo científico publicado en 2010

Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

artículo científico publicado en 2019

Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene.

artículo científico publicado en 1998

Sequencing 5-methylcytosine residues in genomic DNA.

artículo científico publicado en 1994

Serum Free Methylated Glutathione S-transferase 1 DNA Levels, Survival, and Response to Docetaxel in Metastatic, Castration-resistant Prostate Cancer: Post Hoc Analyses of Data from a Phase 3 Trial

scientific article published on 19 November 2018

Sp1 binding is inhibited by (m)Cp(m)CpG methylation.

artículo científico

Telomere-Driven Karyotypic Complexity Concurs with p16INK4a Inactivation in TP53-Competent Immortal Endothelial Cells

articulo cientifico

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

artículo científico publicado en 2016

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

artículo científico publicado en 2004

Transient exposure to miR-203 enhances the differentiation capacity of established pluripotent stem cells

artículo científico publicado en 2020

Widespread Aberrant Alternative Splicing despite Molecular Remission in Chronic Myeloid Leukaemia Patients

artículo científico publicado en 2020

ZNF300P1 encodes a lincRNA that regulates cell polarity and is epigenetically silenced in type II epithelial ovarian cancer

artículo científico publicado en 2014

miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

artículo científico publicado en 2011

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