Filtros de búsqueda

Lista de obras de Janko Nikolich-Zugich

A critical role for the cytoplasmic tail of pTα in T lymphocyte development

article

A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.

artículo científico publicado en 2018

Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses

artículo científico publicado en 2013

Acute systemic DNA damage in youth does not impair immune defense with aging

artículo científico publicado en 2016

Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging

scientific article published on 11 March 2020

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

artículo científico publicado en 2012

Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA

artículo científico publicado en 2013

Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense

artículo científico publicado en 2004

Age-related CD8+ T cell clonal expansions express elevated levels of CD122 and CD127 and display defects in perceiving homeostatic signals

artículo científico publicado en 2006

Age-related changes in CD8 T cell homeostasis and immunity to infection

artículo científico publicado en 2012

Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replication

artículo científico publicado en 2008

Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections

artículo científico publicado en 2008

Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans

artículo científico publicado en 2014

Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories

artículo científico publicado en 2014

An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned

artículo científico publicado en 2015

Antibody Responses to SARS-CoV-2: Let's Stick to Known Knowns

scientific article published on 04 September 2020

Author Correction: Charles D. Surh 1960-2017.

artículo científico publicado en 2017

Author Correction: The twilight of immunity: emerging concepts in aging of the immune system

artículo científico publicado en 2018

CMV and Immunosenescence: from basics to clinics

artículo científico publicado en 2012

Charles D. Surh 1960-2017.

artículo científico publicado en 2017

Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice

artículo científico publicado en 2013

Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.

artículo científico publicado en 2007

Correction: Loss of Naive T Cells and Repertoire Constriction Predict Poor Response to Vaccination in Old Primates

Cutting Edge: The Aging Immune System Reveals the Biological Impact of Direct Antigen Presentation on CD8 T Cell Responses

artículo científico publicado en 2017

Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I decay rates

scientific article published on October 2008

Cytomegalovirus (CMV) research in immune senescence comes of age: overview of the 6th International Workshop on CMV and Immunosenescence.

artículo científico publicado en 2017

Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging

artículo científico publicado en 2012

Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques

artículo científico publicado en 2011

Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates

artículo científico publicado en 2006

Development and migration of protective CD8+ T cells into the nervous system following ocular herpes simplex virus-1 infection

artículo científico publicado en 2005

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

artículo científico publicado en 2002

Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection

artículo científico publicado en 2010

Do cytomegalovirus-specific memory T cells interfere with new immune responses in lymphoid tissues?

artículo científico publicado en 2019

Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates

artículo científico publicado en 2007

Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus

artículo científico publicado en 2016

Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques

artículo científico publicado en 2015

Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells

artículo científico publicado en 2006

Evolution of the antigen-specific CD8+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire

artículo científico publicado en 2011

Exclusion and inclusion of TCR alpha proteins during T cell development in TCR-transgenic and normal mice

artículo científico publicado en 2004

Functional CD8 T cell memory responding to persistent latent infection is maintained for life

artículo científico publicado en 2011

Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma

artículo científico publicado en 2017

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

artículo científico publicado en 2015

High specificity, not degeneracy, allows T cell alloresponses

scientific article published on 01 April 2007

Histone deacetylation critically determines T cell subset radiosensitivity

artículo científico publicado en 2014

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

artículo científico publicado en 2016

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

artículo científico publicado en 2013

Immune Protection against Virus Challenge in Aging Mice Is Not Affected by Latent Herpesviral Infections

artículo científico publicado en 2015

Immune memory and aging: an infinite or finite resource?

artículo científico publicado en 2010

Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections

artículo científico publicado en 2014

Immune response to the West Nile virus in aged non-human primates

artículo científico publicado en 2010

Immune responses in the skin in old age.

artículo científico publicado en 2011

Impact of early life exposure to ionizing radiation on influenza vaccine response in an elderly Japanese cohort

artículo científico publicado en 2018

Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice

artículo científico publicado en 2011

Increased efficiency of phorbol ester-induced lytic reactivation of Kaposi's sarcoma-associated herpesvirus during S phase

artículo científico publicado en 2005

Induction of the cellular microRNA, Hs_154, by West Nile virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors

artículo científico publicado en 2012

Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens

artículo científico publicado en 2009

Intrinsic and extrinsic contributors to defective CD8+ T cell responses with aging

artículo científico publicado en 2018

Key research opportunities in immune system aging

artículo científico publicado en 2009

Key role of T cell defects in age-related vulnerability to West Nile virus

artículo científico publicado en 2009

Known unknowns: how might the persistent herpesvirome shape immunity and aging?

artículo científico publicado en 2017

Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life

artículo científico publicado en 2012

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

artículo científico publicado en 2014

Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates

artículo científico publicado en 2010

Lost in translation: mice, men and cutaneous immunity in old age.

artículo científico publicado en 2014

MIFlowCyt: the minimum information about a Flow Cytometry Experiment

artículo científico publicado en 2008

Mice and flies and monkeys too: caloric restriction rejuvenates the aging immune system of non-human primates

artículo científico publicado en 2005

Molecular, cellular, and antigen requirements for development of age-associated T cell clonal expansions in vivo

artículo científico publicado en 2006

Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus

artículo científico publicado en 2014

New advances in CMV and immunosenescence

artículo científico publicado en 2014

Non-human primate models of T-cell reconstitution

artículo científico publicado en 2007

Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

artículo científico publicado en 2011

Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates

artículo científico publicado en 2008

Phenotypic and functional T-cell aging in rhesus macaques (Macaca mulatta): differential behavior of CD4 and CD8 subsets

artículo científico publicado en 2003

Protective capacity and epitope specificity of CD8(+) T cells responding to lethal West Nile virus infection

artículo científico publicado en 2007

Repeated in vivo stimulation of T and B cell responses in old mice generates protective immunity against lethal West Nile virus encephalitis

artículo científico publicado en 2011

Report from the second cytomegalovirus and immunosenescence workshop

artículo científico publicado en 2011

Role of cell-intrinsic and environmental age-related changes in altered maintenance of murine T cells in lymphoid organs

artículo científico publicado en 2017

Sex differences in T-lymphocyte tissue infiltration and development of angiotensin II hypertension

artículo científico publicado en 2014

Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans

artículo científico publicado en 2009

Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution

artículo científico publicado en 2004

Sultam Thiourea Inhibition of West Nile Virus

artículo científico publicado en 2007

T cell aging: naive but not young

artículo científico publicado en 2005

T cell recognition of an engineered MHC class I molecule: implications for peptide-independent alloreactivity

artículo científico publicado en 2002

The Global Thymus Network: past, present and future

scientific article published on 08 April 2009

The aging immune system: Challenges for the 21st century ⬇️

artículo científico publicado el 1 de octubre de 2012

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence

The many important facets of T-cell repertoire diversity

artículo científico publicado en 2004

The role of mhc polymorphism in anti-microbial resistance

artículo científico publicado en 2004

The twilight of immunity: emerging concepts in aging of the immune system

artículo científico publicado en 2017

Transcriptome-wide characterization of human cytomegalovirus in natural infection and experimental latency

artículo científico publicado en 2017

Translational research in immune senescence: assessing the relevance of current models

artículo científico publicado en 2012

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging

artículo científico publicado en 2013

Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans

artículo científico publicado en 2013

West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function

artículo científico publicado en 2009

West Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of v 3 Integrin

artículo científico publicado en 2008

West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis

artículo científico publicado en 2007

West Nile virus-specific CD4 T cells exhibit direct antiviral cytokine secretion and cytotoxicity and are sufficient for antiviral protection

artículo científico publicado en 2008

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda