Lista de obras - Geert Berx - Dominio Público Uruguay

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

artículo científico publicado en 2008

A new mouse model to study the role of ectopic Nanos3 expression in cancer.

artículo científico publicado en 2019

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

artículo científico publicado en 2014

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

scientific article published on 06 May 2019

Allelic imbalance at the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types.

artículo científico publicado en 1997

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

artículo científico publicado en 2009

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

artículo científico publicado en 2018

An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene

artículo científico publicado en 1997

Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization

artículo científico publicado en 1995

Cadherins and epithelial-to-mesenchymal transition

artículo científico

Cadherins in cancer

artículo científico publicado en 2004

Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).

artículo científico publicado en 1995

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

artículo científico publicado en 2004

Concepts of metastasis in flux: the stromal progression model

artículo científico publicado en 2012

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

artículo científico publicado en 2017

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

artículo científico publicado en 2005

Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability

artículo científico publicado en 2014

Development and characterization of a new human hepatic cell line.

artículo científico publicado en 2015

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.

artículo científico publicado en 2007

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

artículo científico publicado en 2013

Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer

artículo científico publicado en 1999

Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.

artículo científico publicado en 1998

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

article

E-cadherin gene alterations are rare events in thyroid tumors

article

E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas

scientific article published on 01 April 1999

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis ⬇️

artículo científico publicado el 1 de enero de 1997

E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.

artículo científico publicado en 1996

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

artículo científico publicado en 2017

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

artículo científico publicado en 2017

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

artículo científico publicado en 2009

Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation

artículo científico publicado en 2016

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

artículo científico publicado en 2013

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity.

artículo científico publicado en 2017

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

artículo científico

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

artículo científico publicado en 2018

Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours

scientific article published on 01 May 2001

From neural crest cells to melanocytes: cellular plasticity during development and beyond

artículo científico publicado en 2019

Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.

artículo científico publicado en 2003

Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise

artículo científico publicado en 2012

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

scientific article published on 25 June 2018

Genomic organization of the human beta-catenin gene (CTNNB1).

artículo científico publicado en 1996

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.

artículo científico publicado en 2017

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study

artículo científico publicado en 2019

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

artículo científico publicado en 2014

Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online

artículo científico publicado en 1999

Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries

artículo científico publicado en 2003

Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes

artículo científico publicado en 2002

Identification of putative cancer genes through data integration and comparative genomics between plants and humans.

artículo científico publicado en 2012

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

artículo científico publicado en 2020

Involvement of members of the cadherin superfamily in cancer

artículo científico publicado en 2009

Isolation and characterization of a human pseudogene (CTNNAP1) for alpha E-catenin (CTNNA1): assignment of the pseudogene to 5q22 and the alpha E-catenin gene to 5q31.

artículo científico publicado en 1995

Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression

artículo científico publicado en 2010

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

artículo científico publicado en 2016

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

artículo científico publicado en 2002

Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity.

artículo científico

Modulation of iron transport proteins in human colorectal carcinogenesis

artículo científico publicado en 2006

Module network inference from a cancer gene expression data set identifies microRNA regulated modules

artículo científico publicado en 2010

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

artículo científico publicado en 2017

Mutations of the human E-cadherin (CDH1) gene

artículo científico publicado en 1998

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest.

artículo científico publicado en 2015

Nanos genes and their role in development and beyond.

artículo científico publicado en 2018

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

scientific article published on 22 July 2019

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2017

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

artículo científico publicado en 2007

Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis

artículo científico publicado en 1999

Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma

artículo científico publicado en 2010

Regulation of vimentin by SIP1 in human epithelial breast tumor cells.

artículo científico

Regulatory networks defining EMT during cancer initiation and progression

artículo científico

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

artículo científico publicado en 2005

Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinomain situ ⬇️

artículo científico publicado el 1 de diciembre de 1997

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells

artículo científico publicado en 2002

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

artículo científico publicado en 2015

Snail in the frame of malignant tumor recurrence

artículo científico publicado en 2006

Snail promotes Wnt target gene expression and interacts with beta-catenin

artículo científico publicado en 2008

Strategies for immortalization of primary hepatocytes

artículo científico publicado en 2014

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

artículo científico publicado en 2017

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

artículo científico publicado en 2017

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

artículo científico publicado en 2015

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression

artículo científico publicado en 2008

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression

artículo científico publicado en 2001

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization

artículo científico publicado en 2011

The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair

artículo científico publicado en 2010

The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance

scientific article published on 17 June 2019

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

scientific article published on 31 July 2018

The cell-cell adhesion molecule E-cadherin.

artículo científico publicado en 2008

The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer.

artículo científico publicado en 1999

The role of the ZEB family of transcription factors in development and disease.

artículo científico publicado en 2009

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

artículo científico publicado en 2016

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program.

artículo científico publicado en 2005

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

artículo científico publicado en 2001

Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells

artículo científico publicado en 2016

Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair

artículo científico publicado en 2009

Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression

artículo científico publicado en 2008

Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells.

artículo científico publicado en 1995

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.

artículo científico publicado en 2015

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

artículo científico publicado en 2018

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

artículo científico publicado en 2006

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

artículo científico publicado en 2016

Xenogen-free isolation and culture of human adipose mesenchymal stem cells

scientific article published on 08 August 2019

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

artículo científico publicado en 2015

ZEB2 in T-cells and T-ALL

artículo científico publicado en 2019

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

artículo científico publicado en 2018

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

artículo científico publicado en 2014

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

artículo científico publicado en 2016

p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

artículo científico publicado en 2016

Lista de obras de Geert Berx

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

A new mouse model to study the role of ectopic Nanos3 expression in cancer.

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Allelic imbalance at the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types.

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene

Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization

Cadherins and epithelial-to-mesenchymal transition

Cadherins in cancer

Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

Concepts of metastasis in flux: the stromal progression model

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability

Development and characterization of a new human hepatic cell line.

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer

Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

E-cadherin gene alterations are rare events in thyroid tumors

E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis ⬇️

E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity.

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours

From neural crest cells to melanocytes: cellular plasticity during development and beyond

Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.

Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Genomic organization of the human beta-catenin gene (CTNNB1).

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online

Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries

Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes

Identification of putative cancer genes through data integration and comparative genomics between plants and humans.

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

Involvement of members of the cadherin superfamily in cancer

Isolation and characterization of a human pseudogene (CTNNAP1) for alpha E-catenin (CTNNA1): assignment of the pseudogene to 5q22 and the alpha E-catenin gene to 5q31.

Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity.

Modulation of iron transport proteins in human colorectal carcinogenesis

Module network inference from a cancer gene expression data set identifies microRNA regulated modules

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

Mutations of the human E-cadherin (CDH1) gene

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest.

Nanos genes and their role in development and beyond.

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis

Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma

Regulation of vimentin by SIP1 in human epithelial breast tumor cells.

Regulatory networks defining EMT during cancer initiation and progression

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinomain situ ⬇️

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Snail in the frame of malignant tumor recurrence

Snail promotes Wnt target gene expression and interacts with beta-catenin

Strategies for immortalization of primary hepatocytes

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression