Lista de obras - Adrian Velazquez-campoy - Dominio Público Uruguay

2-oxoglutarate modulates the affinity of FurA for the ntcA promoter in Anabaena sp. PCC 7120

scientific article published on 29 September 2019

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

artículo científico publicado en 2017

A New Member Of The Thioredoxin Reductase Family From Early Oxygenic Photosynthetic Organisms

artículo científico publicado en 2016

A Non-Invasive NMR Method Based on Histidine Imidazoles to Analyze the pH-Modulation of Protein-Nucleic Acid Interfaces

artículo científico

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

scientific article published on 11 September 2020

A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility

artículo científico publicado en 2016

A look at ligand binding thermodynamics in drug discovery

artículo científico publicado en 2017

A mechanism for histone chaperoning activity of nucleoplasmin: thermodynamic and structural models

artículo científico publicado en 2009

A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease

artículo científico publicado en 2004

A unified framework based on the binding polynomial for characterizing biological systems by isothermal titration calorimetry.

artículo científico publicado en 2014

AFFINImeter: A software to analyze molecular recognition processes from experimental data

artículo científico publicado en 2019

Allosteric inhibitors of the NS3 protease from the hepatitis C virus

artículo científico publicado en 2013

Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1)

artículo científico publicado en 2018

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes

artículo científico publicado en 2002

An Alternative Homodimerization Interface of MnmG Reveals a Conformational Dynamics that Is Essential for Its tRNA Modification Function

scientific article published on 02 June 2018

Antimalarial activity of cupredoxins: the interaction of Plasmodium merozoite surface protein 119 (MSP119) and rusticyanin

artículo científico publicado en 2013

Arabidopsis FNRL protein is an NADPH-dependent chloroplast oxidoreductase resembling bacterial ferredoxin-NADP+ reductases

artículo científico publicado en 2017

Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors Against Conformational and Infectious Diseases

artículo científico publicado en 2016

Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.

artículo científico publicado en 2018

Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes

artículo científico publicado en 2001

Characterization of Protein-Protein Interactions by Isothermal Titration Calorimetry

Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability.

artículo científico publicado en 2014

Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5.

artículo científico publicado en 2007

Conformational stability of hepatitis C virus NS3 protease

artículo científico publicado en 2010

Contribution of disulfide bonds to stability, folding, and amyloid fibril formation: the PI3-SH3 domain case

artículo científico publicado en 2011

Cyanobacterial electron carrier proteins as electron donors to CYP106A2 from Bacillus megaterium ATCC 13368.

artículo científico publicado en 2009

Cysteine Mutational Studies Provide Insight into a Thiol-Based Redox Switch Mechanism of Metal and DNA Binding in FurA from Anabaena sp. PCC 7120.

artículo científico

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

artículo científico publicado en 2018

Cytochrome c1 exhibits two binding sites for cytochrome c in plants

artículo científico

DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway

artículo científico publicado en 2017

Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity

artículo científico publicado en 2013

Deconvolution analysis for classifying gastric adenocarcinoma patients based on differential scanning calorimetry serum thermograms.

artículo científico publicado en 2015

Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1

scientific article published on 24 June 2019

Dendrimers as potential inhibitors of the dimerization of the capsid protein of HIV-1.

artículo científico publicado en 2010

Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice

artículo científico publicado en 2019

Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm

scientific article published on 16 May 2019

Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies

artículo científico publicado en 2013

Differential NtcA Responsiveness to 2-Oxoglutarate Underlies the Diversity of C/N Balance Regulation in Prochlorococcus.

artículo científico publicado en 2017

Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants

artículo científico publicado en 2014

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

artículo científico

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection

artículo científico publicado en 2009

Emissive Enhancement of the Singlet Oxygen Chemiluminescence Probe after Binding to Bovine Serum Albumin

scientific article published on 01 July 2019

Energetic effects of magnesium in the recognition of adenosine nucleotides by the F(1)-ATPase beta subunit.

artículo científico publicado en 2010

Energetics of nucleotide-induced DnaK conformational states

artículo científico publicado en 2010

Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.

artículo científico publicado en 2009

Exact analysis of heterotropic interactions in proteins: Characterization of cooperative ligand binding by isothermal titration calorimetry

artículo científico publicado en 2006

Experimental validation of in silico target predictions on synergistic protein targets

article

Experimental validation of in silico target predictions on synergistic protein targets.

artículo científico publicado en 2013

Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts

artículo científico publicado en 2014

Fluid interface calorimetry

Geometric features of the Wiseman isotherm in isothermal titration calorimetry

article published in 2015

GrpE N-terminal domain contributes to the interaction with Dnak and modulates the dynamics of the chaperone substrate binding domain

artículo científico publicado en 2007

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

artículo científico publicado en 2015

HIV-1 protease inhibitors: enthalpic versus entropic optimization of the binding affinity.

artículo científico publicado en 2000

Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c

artículo científico publicado en 2016

ITC in the post-genomic era...? Priceless

artículo científico publicado en 2004

Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator

artículo científico publicado en 2009

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

artículo científico publicado en 2004

Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria

artículo científico publicado en 2008

Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

scientific article published on 05 August 2019

Improved flavodoxin inhibitors with potential therapeutic effects against Helicobacter pylori infection.

artículo científico publicado en 2013

Incorporating target heterogeneity in drug design

artículo científico publicado en 2001

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

artículo científico publicado en 2016

Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c

artículo científico publicado en 2021

Isolated noncatalytic and catalytic subunits of F1-ATPase exhibit similar, albeit not identical, energetic strategies for recognizing adenosine nucleotides.

artículo científico publicado en 2013

Isothermal titration calorimetry to determine association constants for high-affinity ligands

artículo científico publicado en 2006

Isothermal titration calorimetry.

artículo científico publicado en 2004

Isothermal titration calorimetry: general formalism using binding polynomials.

artículo científico publicado en 2009

Kinetics and thermodynamics of chlorpromazine interaction with lipid bilayers: effect of charge and cholesterol

artículo científico publicado en 2012

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2017

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

artículo científico publicado en 2014

Ligand binding to one-dimensional lattice-like macromolecules: Analysis of the McGhee–von Hippel theory implemented in isothermal titration calorimetry

article

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

artículo científico publicado en 2019

Low-density lipoprotein receptor is a calcium/magnesium sensor - role of LR4 and LR5 ion interaction kinetics in low-density lipoprotein release in the endosome

artículo científico publicado en 2014

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

scientific article published on 10 October 2019

Mechanism of FMN Binding to the Apoflavodoxin from Helicobacter pylori

artículo científico publicado en 2011

Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2+ affinity of the fifth binding module of the LDL receptor.

artículo científico publicado en 2008

Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

artículo científico publicado en 2019

Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase

artículo científico publicado en 2021

Microcystin-LR Binds Iron, and Iron Promotes Self-Assembly.

artículo científico publicado en 2017

Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2

artículo científico publicado en 2020

Molecular basis for the integration of environmental signals by FurB from Anabaena sp. PCC 7120.

artículo científico publicado en 2017

Molecular crowding effects on the distribution of amphiphiles in biological media

artículo científico publicado en 2019

Molecular recognition in the interaction of chloroplast 2-Cys peroxiredoxin with NADPH-thioredoxin reductase C (NTRC) and thioredoxinx

artículo científico publicado en 2014

NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.

artículo científico publicado en 2012

NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain

artículo científico publicado en 2013

On the link between conformational changes, ligand binding and heat capacity

artículo científico

On the temperature dependence of complex formation between chitosan and proteins

artículo científico publicado en 2011

Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease

artículo científico publicado en 2002

Partition of amphiphilic molecules to lipid bilayers by isothermal titration calorimetry

artículo científico publicado en 2009

Peptides as inhibitors of the first phosphorylation step of the Streptomyces coelicolor phosphoenolpyruvate: sugar phosphotransferase system.

artículo científico publicado en 2012

Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase

artículo científico publicado en 2013

Protease inhibition in African subtypes of HIV-1.

artículo científico publicado en 2003

Protein-cation interactions: structural and thermodynamic aspects.

artículo científico publicado en 2011

Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog.

artículo científico publicado en 2017

Rational stabilization of complex proteins: a divide and combine approach

artículo científico publicado en 2015

Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity

artículo científico publicado en 2011

Redox- and Ligand Binding-Dependent Conformational Ensembles in the Human Apoptosis-Inducing Factor Regulate Its Pro-Life and Cell Death Functions

scientific article published on 11 January 2019

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.

artículo científico publicado en 2016

Repurposing Dihydropyridines for Treatment of Helicobacter pylori Infection

scientific article published on 15 December 2019

Rescuing compound bioactivity in a secondary cell-based screening by using γ-cyclodextrin as a molecular carrier.

artículo científico publicado en 2015

Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength

artículo científico publicado en 2015

Selective Targeting of Human and Animal Pathogens of the Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies

Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M and Its Antiviral Activity in Cells against SARS-CoV-2

artículo científico publicado en 2021

Shell Cross-Linked Polymeric Micelles as Camptothecin Nanocarriers for Anti-HCV Therapy.

artículo científico publicado en 2015

Small Molecule Inhibitors of the Response Regulator ArsR Exhibit Bactericidal Activity against Helicobacter pylori

scientific article published on 01 April 2020

Spatial arrangement of LD motif-interacting residues on focal adhesion targeting domain of Focal Adhesion Kinase determine domain-motif interaction affinity and specificity

scientific article published on 30 October 2019

Stability and binding of the phosphorylated species of the N-terminal domain of enzyme I and the histidine phosphocarrier protein from the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system.

artículo científico publicado en 2012

Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position

scientific article published on 12 March 2019

Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target

artículo científico publicado en 2016

Structural Analysis of the Regulation of the DYNLL/LC8 Binding to Nek9 by Phosphorylation

artículo científico publicado en 2013

Structural Basis for Dual-Inhibition Mechanism of a Non-Classical Kazal-Type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin

artículo científico publicado en 2011

Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans

artículo científico publicado en 2015

Structural Basis for the Interaction of Unstructured Neuron Specific Substrates Neuromodulin and Neurogranin with Calmodulin

artículo científico publicado en 2013

Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom

artículo científico publicado en 2008

Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence

artículo científico publicado en 2016

Structural and functional analysis of novel human cytochrome C targets in apoptosis

artículo científico publicado en 2014

Structural and functional characterization of phosphomimetic mutants of cytochrome c at threonine 28 and serine 47.

artículo científico publicado en 2016

Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.

artículo científico publicado en 2015

Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design

artículo científico publicado en 2003

Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c.

artículo científico publicado en 2015

Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48

artículo científico publicado en 2017

Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

scientific article published on 01 July 2019

Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-tumoral Drug PALA

artículo científico publicado en 2016

Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes

artículo científico publicado en 2013

Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme

artículo científico publicado en 2009

Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry

artículo científico publicado en 2012

Synthesis and Characterization of a Lipidic Alpha Amino Acid: Solubility and Interaction with Serum Albumin and Lipid Bilayers

artículo científico publicado en 2013

Targeting intrinsically disordered proteins involved in cancer

scientific article published on 30 October 2019

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma

artículo científico publicado en 2019

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements.

artículo científico publicado en 2017

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

artículo científico publicado en 2020

The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis

artículo científico publicado en 2018

The application of thermodynamic methods in drug design

article by Adrian Velazquez-campoy et al published December 2001 in Thermochimica Acta

The binding energetics of first- and second-generation HIV-1 protease inhibitors: implications for drug design

artículo científico publicado en 2001

The flavodoxin from Helicobacter pylori: structural determinants of thermostability and FMN cofactor binding.

artículo científico publicado en 2007

The histidine phosphocarrier protein, HPr, binds to the highly thermostable regulator of sigma D protein, Rsd, and its isolated helical fragments.

artículo científico publicado en 2017

The histidine-phosphocarrier protein of the phosphoenolpyruvate: sugar phosphotransferase system of Bacillus sphaericus self-associates.

artículo científico publicado en 2013

The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.

artículo científico publicado en 2017

The isolated major homology region of the HIV capsid protein is mainly unfolded in solution and binds to the intact protein

article

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2017

Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase

artículo científico publicado en 2011

Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

artículo científico publicado en 2020

Thermal Liquid Biopsy (TLB): A Predictive Score Derived from Serum Thermograms as a Clinical Tool for Screening Lung Cancer Patients

artículo científico publicado en 2019

Thermal liquid biopsy for monitoring melanoma patients under surveillance during treatment: A pilot study

artículo científico publicado en 2018

Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant†

article

Thermodynamic analysis of ferrous ion binding to Escherichia coli ferritin EcFtnA.

artículo científico publicado en 2005

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets

artículo científico publicado en 2004

Thermodynamics of cooperative binding of FAD to human NQO1: Implications to understanding cofactor-dependent function and stability of the flavoproteome

artículo científico publicado en 2017

Thermodynamics of protein-cation interaction: Ca+2 and Mg+2 binding to the fifth binding module of the LDL receptor

artículo científico publicado en 2010

Thermodynamics of zinc binding to hepatitis C virus NS3 protease: a folding by binding event

artículo científico publicado en 2009

Tinkering with Binding Polynomials in Isothermal Titration Calorimetry

artículo científico publicado en 2019

Towards the competent conformation for catalysis in the ferredoxin-NADP+ reductase from the Brucella ovis pathogen

scientific article published on 05 August 2019

Unexpected diversity of ferredoxin-dependent thioredoxin reductases in cyanobacteria

artículo científico publicado en 2021

Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase.

artículo científico publicado en 2017

Unspecific Cooperative Ligand Binding to One-Dimensional Lattice-like Macromolecules

scholarly article by Adrian Velazquez-campoy published 2006 in AIP Conference Proceedings

Unsupervised bubble calorimetry analysis: Surface tension from isothermal titration calorimetry

Unveiling the Binding between the Armadillo-Repeat Domain of Plakophilin 1 and the Intrinsically Disordered Transcriptional Repressor RYBP

artículo científico publicado en 2024

W196 and the <i>β</i>-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor

artículo científico publicado en 2021

Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

artículo científico publicado en 2012

l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells

artículo científico publicado en 2021

Lista de obras de Adrian Velazquez-campoy

2-oxoglutarate modulates the affinity of FurA for the ntcA promoter in Anabaena sp. PCC 7120

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

A New Member Of The Thioredoxin Reductase Family From Early Oxygenic Photosynthetic Organisms

A Non-Invasive NMR Method Based on Histidine Imidazoles to Analyze the pH-Modulation of Protein-Nucleic Acid Interfaces

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility

A look at ligand binding thermodynamics in drug discovery

A mechanism for histone chaperoning activity of nucleoplasmin: thermodynamic and structural models

A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease

A unified framework based on the binding polynomial for characterizing biological systems by isothermal titration calorimetry.

AFFINImeter: A software to analyze molecular recognition processes from experimental data

Allosteric inhibitors of the NS3 protease from the hepatitis C virus

Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1)

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes

An Alternative Homodimerization Interface of MnmG Reveals a Conformational Dynamics that Is Essential for Its tRNA Modification Function

Antimalarial activity of cupredoxins: the interaction of Plasmodium merozoite surface protein 119 (MSP119) and rusticyanin

Arabidopsis FNRL protein is an NADPH-dependent chloroplast oxidoreductase resembling bacterial ferredoxin-NADP+ reductases

Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors Against Conformational and Infectious Diseases

Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.

Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes

Characterization of Protein-Protein Interactions by Isothermal Titration Calorimetry

Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability.

Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5.

Conformational stability of hepatitis C virus NS3 protease

Contribution of disulfide bonds to stability, folding, and amyloid fibril formation: the PI3-SH3 domain case

Cyanobacterial electron carrier proteins as electron donors to CYP106A2 from Bacillus megaterium ATCC 13368.

Cysteine Mutational Studies Provide Insight into a Thiol-Based Redox Switch Mechanism of Metal and DNA Binding in FurA from Anabaena sp. PCC 7120.

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

Cytochrome c1 exhibits two binding sites for cytochrome c in plants

DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway

Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity

Deconvolution analysis for classifying gastric adenocarcinoma patients based on differential scanning calorimetry serum thermograms.

Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1

Dendrimers as potential inhibitors of the dimerization of the capsid protein of HIV-1.

Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice

Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm

Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies

Differential NtcA Responsiveness to 2-Oxoglutarate Underlies the Diversity of C/N Balance Regulation in Prochlorococcus.

Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection

Emissive Enhancement of the Singlet Oxygen Chemiluminescence Probe after Binding to Bovine Serum Albumin

Energetic effects of magnesium in the recognition of adenosine nucleotides by the F(1)-ATPase beta subunit.

Energetics of nucleotide-induced DnaK conformational states

Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.

Exact analysis of heterotropic interactions in proteins: Characterization of cooperative ligand binding by isothermal titration calorimetry

Experimental validation of in silico target predictions on synergistic protein targets

Experimental validation of in silico target predictions on synergistic protein targets.

Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts

Fluid interface calorimetry

Geometric features of the Wiseman isotherm in isothermal titration calorimetry

GrpE N-terminal domain contributes to the interaction with Dnak and modulates the dynamics of the chaperone substrate binding domain

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

HIV-1 protease inhibitors: enthalpic versus entropic optimization of the binding affinity.

Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c

ITC in the post-genomic era...? Priceless

Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria

Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

Improved flavodoxin inhibitors with potential therapeutic effects against Helicobacter pylori infection.

Incorporating target heterogeneity in drug design

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c

Isolated noncatalytic and catalytic subunits of F1-ATPase exhibit similar, albeit not identical, energetic strategies for recognizing adenosine nucleotides.

Isothermal titration calorimetry to determine association constants for high-affinity ligands

Isothermal titration calorimetry.

Isothermal titration calorimetry: general formalism using binding polynomials.

Kinetics and thermodynamics of chlorpromazine interaction with lipid bilayers: effect of charge and cholesterol

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

Ligand binding to one-dimensional lattice-like macromolecules: Analysis of the McGhee–von Hippel theory implemented in isothermal titration calorimetry

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

Low-density lipoprotein receptor is a calcium/magnesium sensor - role of LR4 and LR5 ion interaction kinetics in low-density lipoprotein release in the endosome

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

Mechanism of FMN Binding to the Apoflavodoxin from Helicobacter pylori

Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2+ affinity of the fifth binding module of the LDL receptor.

Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase