Lista de obras - Sinead Weldon - Dominio Público Uruguay

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation

artículo científico publicado en 2014

A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung

artículo científico publicado en 2015

A secretory leukocyte protease inhibitor variant with improved activity against lung infection

artículo científico publicado en 2015

Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.

artículo científico publicado en 2017

Airway Inflammation and Host Responses in the Era of CFTR Modulators

artículo científico publicado en 2020

Antiproteases as therapeutics to target inflammation in cystic fibrosis.

artículo científico publicado en 2010

At the forefront of cystic fibrosis Basic Science research: 16th ECFS Basic Science Conference

scientific article published on 13 February 2020

Characterisation of eppin function: expression and activity in the lung

artículo científico publicado en 2017

Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages

artículo científico publicado en 2004

Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).

artículo científico publicado en 2018

Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation

artículo científico publicado en 2009

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.

artículo científico publicado en 2006

Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis

artículo científico publicado en 2008

Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.

artículo científico publicado en 2011

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.

artículo científico publicado en 2010

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

artículo científico publicado en 2011

Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis ⬇️

artículo científico publicado el 2 de agosto de 2010

Inflammation and host-pathogen interaction: Cause and consequence in cystic fibrosis lung disease.

artículo científico publicado en 2017

Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.

artículo científico publicado en 2017

Innate host defense functions of secretory leucoprotease inhibitor.

artículo científico publicado en 2007

LPS induced tissue factor expression in the THP-1 monocyte cell line is attenuated by conjugated linoleic acid

artículo científico publicado en 2006

Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease

scientific article published on 01 March 2020

Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field

artículo científico publicado en 2018

Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2018

Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function

artículo científico publicado en 2019

Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury

artículo científico publicado en 2012

Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice

artículo científico publicado en 2014

SLPI and elafin: multifunctional antiproteases of the WFDC family.

artículo científico publicado en 2011

Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)

scientific article published on 09 July 2020

Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection

artículo científico publicado en 2019

Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding

artículo científico publicado en 2005

Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential

artículo científico publicado en 2020

Targeting of cathepsin S reduces cystic fibrosis-like lung disease

artículo científico publicado en 2019

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity

artículo científico publicado en 2015

The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung ⬇️

artículo científico publicado en 2015

The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma

scholarly article by Akane Tanaka et al published June 2018 in The Journal of Allergy and Clinical Immunology

The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease

artículo científico publicado en 2016

Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.

artículo científico publicado en 2014

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production

artículo científico publicado en 2014

Lista de obras de Sinead Weldon

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation

A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung

A secretory leukocyte protease inhibitor variant with improved activity against lung infection

Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.

Airway Inflammation and Host Responses in the Era of CFTR Modulators

Antiproteases as therapeutics to target inflammation in cystic fibrosis.

At the forefront of cystic fibrosis Basic Science research: 16th ECFS Basic Science Conference

Characterisation of eppin function: expression and activity in the lung

Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages

Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).

Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.

Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis

Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis ⬇️

Inflammation and host-pathogen interaction: Cause and consequence in cystic fibrosis lung disease.

Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.

Innate host defense functions of secretory leucoprotease inhibitor.

LPS induced tissue factor expression in the THP-1 monocyte cell line is attenuated by conjugated linoleic acid

Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease

Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field

Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease

Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function

Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury

Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice

SLPI and elafin: multifunctional antiproteases of the WFDC family.

Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)

Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection

Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding

Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential

Targeting of cathepsin S reduces cystic fibrosis-like lung disease

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity

The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung ⬇️

The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma

The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease

Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production