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Lista de obras de Fahd Al-mulla

<i>ACE2</i> and <i>FURIN</i> variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19

artículo científico publicado en 2021

A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating SARS-CoV-2 with precision medicine

artículo científico publicado en 2020

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes

artículo científico publicado en 2011

A new model for raf kinase inhibitory protein induced chemotherapeutic resistance

artículo científico publicado en 2012

A novel PKD1 variant demonstrates a disease-modifying role in trans with a truncating PKD1 mutation in patients with autosomal dominant polycystic kidney disease.

artículo científico publicado en 2015

ANGPTL4: A Predictive Marker for Diabetic Nephropathy ⬇️

scientific article published on 27 October 2019

Adult Diabetes and Prediabetes Prevalence in Kuwait: Data from the Cross-Sectional Kuwait Diabetes Epidemiology Program

artículo científico publicado en 2020

Age-dependent penetrance of different germline mutations in the BRCA1 gene

artículo científico publicado en 2009

Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats

artículo científico publicado en 2004

Analysis of DNA methylation in FFPE tissues using the MethyLight technology

artículo científico publicado en 2011

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

artículo científico publicado en 2013

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

artículo científico publicado en 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

artículo científico publicado en 2015

Associations of single nucleotide polymorphisms in the adiponectin gene with adiponectin levels and cardio-metabolic risk factors in patients with cancer ⬇️

artículo científico publicado el 1 de enero de 2011

Atherogenic Index of Plasma (AIP) a Tool to Assess Changes in Cardiovascular Disease Risk Post Laparoscopic Sleeve Gastrectomy

artículo científico publicado en 2020

Autoimmune signatures for prediction and diagnosis of autoimmune diabetes in Kuwait

artículo científico publicado en 2019

BRCA1 gene expression in breast cancer in Kuwait: Correlation with prognostic parameters

artículo científico

BRCA1 gene expression in breast cancer: A correlative study between real-time RT-PCR and immunohistochemistry

artículo científico

Biallelic inactivating variants in the GTPBP2 gene cause a neurodevelopmental disorder with severe intellectual disability.

artículo científico publicado en 2018

Bridging genomics research between developed and developing countries: the Genomic Medicine Alliance

Capturing all disease-causing mutations for clinical and research use: toward an effortless system for the Human Variome Project

artículo científico publicado en 2009

Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer

artículo científico publicado en 2001

Causes of genome instability: the effect of low dose chemical exposures in modern society

artículo científico publicado en 2015

Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children

artículo científico publicado en 2018

Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes

scientific journal article

Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions

artículo científico publicado en 2015

Chemically Defined Conditions Mediate an Efficient Induction of Mesodermal Lineage from Human Umbilical Cord- and Bone Marrow- Mesenchymal Stem Cells and Dental Pulp Pluripotent-Like Stem Cells

artículo científico publicado en 2018

Circulating cell-free DNA in sickle cell disease: is it a potentially useful biomarker?

artículo científico publicado en 2014

Clinical implications for loss or diminution of expression of Raf-1 kinase inhibitory protein and its phosphorylated form in ductal breast cancer

artículo científico publicado en 2013

Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer

artículo científico publicado en 2007

Comparative Proteomic Analysis Identifies EphA2 as a Specific Cell Surface Marker for Wharton's Jelly-Derived Mesenchymal Stem Cells

artículo científico publicado en 2020

Comparative genomic hybridization analysis of primary colorectal carcinomas and their synchronous metastases

article

Comparison of the sensitivity and specificity of urine cytology, urinary nuclear matrix protein-22 and multitarget fluorescence in situ hybridization assay in the detection of bladder cancer

research work

Comparison of two probe preparation methods using long oligonucleotide microarrays

artículo científico publicado en 2004

Correction: RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration

artículo científico publicado en 2016

Correlation Profile of Suppression of Tumorigenicity 2 and/or Interleukin-33 with Biomarkers in the Adipose Tissue of Individuals with Different Metabolic States

scientific article published on 20 October 2020

Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents

scientific article published on 14 April 2020

Could nuclear matrix protein 22 (NMP22) play a role with urine cytology in screening for bladder cancer? - Experience at Kuwait University

research work

Decreased carbonyl reductase 1 expression promotes malignant behaviours by induction of epithelial mesenchymal transition and its clinical significance

artículo científico publicado en 2012

Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton's jelly mesenchymal stem cells

artículo científico publicado en 2016

Defining umbilical cord blood stem cells

article

Depletion of the Ras Association Domain Family 1, Isoform A-Associated Novel Microtubule-Associated Protein, C19ORF5/MAP1S, Causes Mitotic Abnormalities

scientific article published on 01 January 2007

Differences in in vitro invasive capacity induced by differences in Ki-Ras protein mutations

artículo científico publicado en 2001

Directed differentiation of umbilical cord blood stem cells into cortical GABAergic neurons

artículo científico publicado en 2013

Discovery and clinical introduction of first-in-class imipridone ONC201.

articulo cientifico

Disruptive chemicals, senescence and immortality

artículo científico publicado en 2015

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

artículo científico publicado en 2015

Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

scientific article published on 16 March 2020

Environmental immune disruptors, inflammation and cancer risk

artículo científico publicado en 2015

Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait

artículo científico publicado en 2016

Evaluation of the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait.

artículo científico publicado en 2012

Expression of Estrogen Receptor a and Estrogen Receptor β in Fine Needle Aspirates of Breast Carcinoma

FIRST INTERNATIONAL WORKSHOP ON "PROGNOSTIC AND THERAPEUTIC APPLICATIONS OF RKIP IN CANCER"

Functionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer.

artículo científico publicado en 2017

GALNT2 rs4846914 SNP Is Associated with Obesity, Atherogenic Lipid Traits, and ANGPTL3 Plasma Level

artículo científico publicado en 2022

Gender influence in EBV antibody response in multiple sclerosis patients from Kuwait.

artículo científico publicado en 2015

Gender-associated genomic differences in colorectal cancer: clinical insight from feminization of male cancer cells

artículo científico publicado en 2014

Generalizability of GWA-Identified Genetic Risk Variants for Metabolic Traits to Populations from the Arabian Peninsula

artículo científico publicado en 2021

Genetic and epigenetic control of RKIP transcription

artículo científico publicado en 2014

Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly

artículo científico publicado en 2013

Genotypic and phenotypic differences between nodal and extranodal diffuse large B-Cell lymphomas

artículo científico publicado en 2011

Global implementation of genomic medicine: We are not alone

artículo científico publicado en 2015

Glycolaldehyde induces apoptosis in a human breast cancer cell line

artículo científico publicado en 2003

Hemizygosity of the MAX Gene Locus in HL60 Cells

article

Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality

articulo cientifico

Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance

scientific article published on 24 July 2019

Human Variome Project country nodes: documenting genetic information within a country

artículo científico publicado en 2012

Human metapneumovirus in patients with respiratory tract infection in Kuwait

Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology

artículo científico publicado en 2018

Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse. ⬇️

artículo científico publicado en 2016

Identification of Maturity-Onset-Diabetes of the Young (MODY) mutations in a country where diabetes is endemic

artículo científico publicado en 2021

Identification of a rare germline NBN gene mutation by whole exome sequencing in a lung-cancer survivor from a large family with various types of cancer

artículo científico publicado en 2016

Immunocytochemical detection of raf kinase inhibitor protein and human papillomavirus profiling of normal and abnormal cervical ThinPrep samples

artículo científico publicado en 2013

Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing

article

Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes

artículo científico publicado en 2011

Increased Adipose Tissue Expression of Interferon Regulatory Factor (IRF)-5 in Obesity: Association with Metabolic Inflammation

artículo científico publicado en 2019

Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study

artículo científico publicado en 2020

Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

artículo científico publicado en 2010

Ketogenic diet attenuates cerebellar atrophy progression in a subject with a biallelic variant at the ATAD3A locus

artículo científico publicado en 2019

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

artículo científico publicado en 2001

LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1

scientific article published on 14 October 2020

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

artículo científico publicado en 2020

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

artículo científico publicado en 2015

Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

artículo científico publicado en 2015

Metastatic recurrence of early-stage colorectal cancer is linked to loss of heterozygosity on chromosomes 4 and 14q.

artículo científico publicado en 2006

Methods for microarray data analysis

artículo científico publicado en 2007

Microarray-Based CGH and Copy Number Analysis of FFPE Samples ⬇️

artículo científico publicado el 1 de enero de 2011

Mitochondrial DNA D-loop sequencing reveals obesity variants in an Arab population.

artículo científico publicado en 2019

Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait

article published in 2014

Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.

artículo científico publicado en 2011

Mutant K-ras2 in serum

artículo científico publicado en 2003

Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes

artículo científico publicado en 2005

Novel Flavonoid Didymin Inhibits Neuroblastomas--Letter

Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation

artículo científico publicado en 2019

Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes

artículo científico publicado en 2005

PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease

artículo científico publicado en 2019

Pathogenic Germline Variants in 10,389 Adult Cancers

artículo científico publicado en 2018

Planning the human variome project: the Spain report.

artículo científico publicado en 2009

Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer

artículo científico publicado en 2012

Prevalence and correlation of human papilloma virus and its types with prognostic markers in patients with invasive ductal carcinoma of the breast in kuwait

artículo científico publicado en 2013

Proliferation and Migration of Peripheral Retinal Pigment Epithelial Cells Are Associated with the Upregulation of Wingless-Related Integration and Bone Morphogenetic Protein Signaling in Dark Agouti Rats

artículo científico publicado en 2016

RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility

artículo científico publicado en 2010

RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.

artículo científico publicado en 2015

RKIP and cellular motility ⬇️

artículo científico publicado el 1 de julio de 2012

RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration.

artículo científico publicado en 2015

RKIP-1 and the Cell Cycle: Novel Insight Into Genomic Instability

RKIP: much more than Raf kinase inhibitory protein

artículo científico

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

artículo científico publicado en 2012

Rabson-Mendenhall Syndrome in a brother-sister pair in Kuwait: Diagnosis and 5 year follow up

artículo científico publicado en 2020

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β.

artículo científico publicado en 2011

Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients

artículo científico publicado en 2013

Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients

artículo científico publicado en 2006

Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability.

artículo científico publicado en 2008

Raf kinase inhibitory protein role in the molecular subtyping of breast cancer

artículo científico publicado en 2014

Real-time tracking and forecasting of the COVID-19 outbreak in Kuwait: a mathematical modeling study

artículo científico publicado en 2020

Recommendations for genetic variation data capture in developing countries to ensure a comprehensive worldwide data collection

artículo científico publicado en 2011

Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer.

artículo científico publicado en 2013

Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis

artículo científico publicado en 2005

Regulation of the MAPK pathway by raf kinase inhibitory protein

artículo científico publicado en 2014

Retracted: Raf Kinase Inhibitor Protein (RKIP) Blocks Signal Transducer and Activator of Transcription 3 (STAT3) Activation in Breast and Prostate Cancer

artículo científico publicado en 2014

Role of Caveolin-1 in Diabetes and Its Complications

artículo científico publicado en 2020

SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains

artículo científico publicado en 2021

Senior-Loken syndrome: A novel NPHP5 gene mutation in a family from Kuwait

article

Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity

scientific article published on 17 March 2020

Statistical Class Separation Using sEMG Features Towards Automated Muscle Fatigue Detection and Prediction

article

Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway

artículo científico publicado en 2020

Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression

artículo científico publicado en 1999

Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.

artículo científico publicado en 2015

Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: carbonyl reductase predicts prognosis and lymph node metastasis

artículo científico publicado en 2011

TNF-α Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-κB Signaling Pathways

artículo científico publicado en 2019

TNF-α Induces a Pro-Inflammatory Phenotypic Shift in Monocytes through ACSL1: Relevance to Metabolic Inflammation

artículo científico publicado en 2019

Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery

artículo científico publicado en 2020

Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy

artículo científico publicado en 2016

The Association of Vitamin D Receptor Polymorphisms with Multiple Sclerosis in a Case-Control Study from Kuwait

artículo científico publicado en 2015

The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target ⬇️

artículo científico

The effect of environmental chemicals on the tumor microenvironment

artículo científico publicado en 2015

The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression

artículo científico publicado en 2012

The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants

artículo científico publicado en 2024

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis

artículo científico publicado en 2015

The influence of admixture and consanguinity on population genetic diversity in Middle East

artículo científico publicado en 2014

The locked genomes: A perspective from Arabia

artículo científico publicado en 2014

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia

artículo científico publicado en 2014

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

artículo científico publicado en 2015

The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up

artículo científico publicado en 2013

The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries

scientific article published on 26 July 2019

Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes

artículo científico publicado en 2014

Uses of microarray platforms in cancer: a correlative study between genomic copy number changes and their expression at mRNA and protein levels

artículo científico publicado en 2007

Utilization of microarray platforms in clinical practice: an insight on the preparation and amplification of nucleic acids from frozen and fixed tissues.

artículo científico publicado en 2007

Which obesity index best explains the link between adipokines, coronary heart disease risk and metabolic abnormalities in type 2 diabetes mellitus?

artículo científico publicado en 2009

Whole genome amplification of DNA extracted from FFPE tissues

artículo científico

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