Lista de obras - Susan Howlett - Dominio Público Uruguay

"Voltage-activated Ca release" in rabbit, rat and guinea-pig cardiac myocytes, and modulation by internal cAMP.

artículo científico publicado en 1997

3H-nitrendipine binding to hamster cardiac muscle homogenate

artículo científico publicado en 1986

A Frailty Index Based on Common Laboratory Tests in Comparison With a Clinical Frailty Index for Older Adults in Long-Term Care Facilities

artículo científico publicado en 2015

A clinical frailty index in aging mice: comparisons with frailty index data in humans

artículo científico publicado en 2013

A frailty index based on laboratory deficits in community-dwelling men predicted their risk of adverse health outcomes

artículo científico publicado en 2016

A procedure for creating a frailty index based on deficit accumulation in aging mice

artículo científico publicado en 2011

Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart

artículo científico publicado en 2016

Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging

artículo científico publicado en 2015

Age and life expectancy clocks based on machine learning analysis of mouse frailty

scientific article published on 15 September 2020

Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion

artículo científico publicado en 2012

Age-associated alterations in retinal arteriole reactivity to endothelin-1 differ between the sexes

artículo científico publicado en 2012

Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats

artículo científico publicado en 2009

Ageing: Develop models of frailty

artículo científico publicado en 2014

Alterations in ventricular KATP channel properties during aging ⬇️

artículo científico publicado el 17 de diciembre de 2012

Animal models of frailty: current applications in clinical research

artículo científico publicado en 2016

Assessment of Frailty in Animal Models

artículo científico

Associations between a laboratory frailty index and adverse health outcomes across age and sex

artículo científico publicado en 2019

Attentuation of cardiac stunning by losartan in a cellular model of ischemia and reperfusion is accompanied by increased sarcoplasmic reticulum Ca2+ stores and prevention of cytosolic Ca2+ elevation

artículo científico publicado en 2004

Beta-adrenoceptor stimulation exacerbates detrimental effects of ischemia and reperfusion in isolated guinea pig ventricular myocytes

artículo científico publicado en 2008

Blood pressure in relation to age and frailty.

artículo científico publicado en 2011

Calcium channels in normal and dystrophic hamster cardiac muscle. [3H]nitrendipine binding studies

artículo científico publicado en 1987

Calcium currents in ventricular myocytes of prehypertrophic cardiomyopathic hamsters.

artículo científico publicado en 1995

Calcium spark properties in ventricular myocytes are altered in aged mice

artículo científico publicado en 2005

Calcium sparks in mouse ventricular myocytes at physiological temperature

artículo científico publicado en 2003

Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature

artículo científico publicado en 2014

Cardiac contraction, calcium transients, and myofilament calcium sensitivity fluctuate with the estrous cycle in young adult female mice.

artículo científico publicado en 2014

Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice

artículo científico publicado en 2006

Changes in excitation-contraction coupling in an isolated ventricular myocyte model of cardiac stunning

artículo científico publicado en 2002

Characterization of membrane N-glycan binding sites of lysozyme for cardiac depression in sepsis.

artículo científico publicado en 2004

Commentary: Age-related neurodegenerative disease research needs aging models

artículo científico publicado en 2016

Contractile properties of myocardium are altered in dystrophin-deficient mdx mice

artículo científico publicado en 1996

Contractions in guinea-pig ventricular myocytes triggered by a calcium-release mechanism separate from Na+ and L-currents

artículo científico publicado en 1995

Contribution of a voltage-sensitive calcium release mechanism to contraction in cardiac ventricular myocytes.

artículo científico publicado en 1998

Defective excitation-contraction coupling in hearts of rats with congestive heart failure

artículo científico publicado en 2005

Deficient priming activity of newborn cord blood-derived polymorphonuclear neutrophilic granulocytes with lipopolysaccharide and tumor necrosis factor-alpha triggered with formyl-methionyl-leucyl-phenylalanine

artículo científico publicado en 1993

Density of 1,4-dihydropyridine receptors decreases in the hearts of aging hamsters

scientific article published on 01 August 1992

Density of Ryanodine Receptors is Increased in Sarcoplasmic Reticulum from Prehypertrophic Cardiomyopathic Hamster Heart

scientific article published on 01 March 1994

Dibenzothiazepinones as potential calcium channel antagonists. I

artículo científico publicado en 1993

Differential effects of phosphodiesterase-sensitive and -resistant analogs of cAMP on initiation of contraction in cardiac ventricular myocytes

artículo científico publicado en 2003

Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes

artículo científico publicado en 2007

Diminished Inotropic Response to Amrinone in Ventricular Myocytes from Myopathic Hamsters Is Linked to Depression of High-Gain Ca2+-Induced Ca2+ Release

artículo científico publicado en 2004

Direct cloning of differential display products eluted from northern blots

artículo científico publicado en 1999

Dysnatremia in Relation to Frailty and Age in Community-dwelling Adults in the National Health and Nutrition Examination Survey.

artículo científico publicado en 2016

Effect of age on cardiac excitation-contraction coupling.

scientific article published on 04 August 2009

Effects of adenosine in simulated ischemia and reperfusion in guinea pig ventricular myocytes

artículo científico publicado en 1995

Effects of ischemia and reperfusion on isolated ventricular myocytes from young adult and aged Fischer 344 rat hearts

artículo científico publicado en 2008

Electrophysiologic differences between normal and dystrophic avian muscle

scientific article published on 01 November 1986

Factors that influence reliability of the mouse clinical frailty index

artículo científico publicado en 2015

Force-interval relation in normal and cardiomyopathic hamster atria

artículo científico publicado en 1991

Frailty: Scaling from Cellular Deficit Accumulation?

artículo científico

H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation.

artículo científico publicado en 2012

Heterogeneity of Human Aging and Its Assessment

artículo científico publicado en 2017

How cardiomyocyte excitation, calcium release and contraction become altered with age.

artículo científico publicado en 2014

Hypothermia increases the gain of excitation-contraction coupling in guinea pig ventricular myocytes

artículo científico publicado en 2008

Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

artículo científico publicado en 2015

In Memoriam: Gregory R. Ferrier, PhD, 1943-2005.

artículo científico publicado en 2006

In contrast to forskolin and 3-isobutyl-1-methylxanthine, amrinone stimulates the cardiac voltage-sensitive release mechanism without increasing calcium-induced calcium release.

artículo científico publicado en 2001

Increased expression of the gene for alpha-interferon-inducible protein in cardiomyopathic hamster heart

artículo científico publicado en 2000

Increases in diastolic [Ca2+] can contribute to positive inotropy in guinea pig ventricular myocytes in the absence of changes in amplitudes of Ca2+ transients

artículo científico publicado en 2006

Ischemia and reperfusion injury following cardioplegic arrest is attenuated by age and testosterone deficiency in male but not female mice

scientific article published on 23 August 2019

L-Arginine ameliorates effects of ischemia and reperfusion in isolated cardiac myocytes

artículo científico publicado en 2003

Lipid-lowering agents and the risk of cognitive impairment that does not meet criteria for dementia, in relation to apolipoprotein E status

artículo científico publicado en 2007

Long-term testosterone deficiency modifies myofilament and calcium-handling proteins and promotes diastolic dysfunction in the aging mouse heart

scientific article published on 18 January 2019

Losartan exerts antiarrhythmic activity independent of angiotensin II receptor blockade in simulated ventricular ischemia and reperfusion.

artículo científico publicado en 1996

Losartan improves recovery of contraction and inhibits transient inward current in a cellular model of cardiac ischemia and reperfusion.

artículo científico publicado en 2000

Microbial shifts in the aging mouse gut.

artículo científico publicado en 2014

Molecular geometries of dibenzothiazepinone and dibenzoxazepinone calcium antagonists

artículo científico publicado en 1995

New horizons in frailty: ageing and the deficit-scaling problem

scientific article published on 05 June 2013

Novel cardioprotection strategies for the aged heart: evidence from pre-clinical studies

artículo científico publicado en 2016

Orthostatic hypotension (OH) and mortality in relation to age, blood pressure and frailty

scientific article published on 10 January 2012

Ovariectomy enhances SR Ca²⁺ release and increases Ca²⁺ spark amplitudes in isolated ventricular myocytes

artículo científico publicado en 2011

Overexpression of human beta2-adrenergic receptors increases gain of excitation-contraction coupling in mouse ventricular myocytes

artículo científico publicado en 2004

Pediatric cardioplegia strategy results in enhanced calcium metabolism and lower serum troponin T.

artículo científico publicado en 2009

Possible mechanisms underlying differences in force production between normal and cardiomyopathic hamster atria

artículo científico publicado en 1991

Pretreatment with pinacidil promotes arrhythmias in an isolated tissue model of cardiac ischemia and reperfusion

artículo científico publicado en 2005

Prevalence, Attributes, and Outcomes of Fitness and Frailty in Community-Dwelling Older Adults: Report From the Canadian Study of Health and Aging

artículo científico publicado en 2004

Protecting the aged heart during cardiac surgery: The potential benefits of del Nido cardioplegia

scientific article published on 24 July 2010

Protein Kinase A-Mediated Phosphorylation Contributes to Enhanced Contraction Observed in Mice That Overexpress beta-Adrenergic Receptor Kinase-1

artículo científico publicado en 2006

Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty

artículo científico publicado en 2020

Radioligand binding to muscle homogenates to quantify receptor and ion channel numbers.

artículo científico publicado en 1988

Regulation of contraction and relaxation by membrane potential in cardiac ventricular myocytes

artículo científico publicado en 2000

Reliability of a Frailty Index Based on the Clinical Assessment of Health Deficits in Male C57BL/6J Mice

artículo científico publicado en 2014

Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges

artículo científico publicado en 2016

Responsiveness of goal attainment scaling in a randomized controlled trial of comprehensive geriatric assessment

artículo científico publicado en 2003

Responsiveness of normal and dystrophic avian muscle to acetylcholine, carbamylcholine and d-tubocurarine.

artículo científico publicado en 1988

Rodent models of frailty and their application in preclinical research

artículo científico publicado en 2019

Role of cAMP-dependent protein kinase A in activation of a voltage-sensitive release mechanism for cardiac contraction in guinea-pig myocytes

artículo científico publicado en 1998

Role of voltage-sensitive release mechanism in depression of cardiac contraction in myopathic hamsters

scientific article published on 01 November 1999

Saralasin suppresses arrhythmias in an isolated guinea pig ventricular free wall model of simulated ischemia and reperfusion

artículo científico publicado en 1995

Sarcoplasmic reticulum calcium release channels in ventricles of older adult hamsters.

artículo científico publicado en 2006

Screening for Frailty in Canada’s Health Care System: A Time for Action

article

Searching for the ideal inotropic agent to rescue a failing heart

scientific article published on 07 June 2011

Sex Differences in the Biology and Pathology of the Aging Heart

artículo científico publicado en 2016

Sex differences in SR Ca(2+) release in murine ventricular myocytes are regulated by the cAMP/PKA pathway

artículo científico publicado en 2014

Sex differences in frailty: A systematic review and meta-analysis

artículo científico publicado en 2016

Sex differences in mechanisms of cardiac excitation-contraction coupling

artículo científico publicado en 2013

Sex differences in mechanisms of cardiac excitation-contraction coupling in rat ventricular myocytes

artículo científico publicado en 2010

Sex differences in the phenotypic expression of avian dystrophy

artículo científico publicado en 1983

Simulated ischaemia and reperfusion in isolated guinea pig ventricular myocytes.

artículo científico publicado en 1994

Simulated ischemia-induced preconditioning of isolated ventricular myocytes from young adult and aged Fischer-344 rat hearts

artículo científico publicado en 2008

Standard laboratory tests to identify older adults at increased risk of death

artículo científico publicado en 2014

Subfractionation of cardiac sarcolemma with wheat-germ agglutinin

artículo científico publicado en 1989

Syntheses, Calcium Channel Agonist-Antagonist Modulation Activities, and Voltage-Clamp Studies of Isopropyl 1,4-Dihydro-2,6-dimethyl-3-nitro- 4-pyridinylpyridine-5-carboxylate Racemates and Enantiomers

artículo científico publicado en 1995

Syntheses, calcium channel agonist-antagonist modulation activities, nitric oxide release, and voltage-clamp studies of 2-nitrooxyethyl 1,4-dihydro- 2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylate enantiomers

artículo científico publicado en 2002

Synthesis and Calcium Channel Modulating Effects of Isopropyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(thienyl)-5-pyridinecarboxylates

artículo científico publicado en 1997

Synthesis and Smooth Muscle Calcium Channel Effects of Dialkyl 1,4-Dihydro-2,6-dimethyl-4-aryl-3,5-pyridinedicarboxylates Containing a Nitrone Moiety in the 4-Aryl Substituent

artículo científico publicado en 1997

Synthesis, characterization, and Ca2+ antagonistic activity of diltiazem metabolites

artículo científico publicado en 1992

Testosterone modulates cardiac contraction and calcium homeostasis: cellular and molecular mechanisms

artículo científico publicado en 2015

The 1996 Merck Frosst Award. The voltage-sensitive release mechanism: a new trigger for cardiac contraction.

artículo científico publicado en 1997

The Na+/Ca2+ exchange inhibitor SEA0400 limits intracellular Ca2+ accumulation and improves recovery of ventricular function when added to cardioplegia

artículo científico publicado en 2014

The Symptoms Targeted for Monitoring in a Web-Based Tracking Tool by Caregivers of People With Dementia and Agitation: Cross-Sectional Study

scientific article published on 28 June 2019

The age-related decrease in catecholamine sensitivity is mediated by beta(1)-adrenergic receptors linked to a decrease in adenylate cyclase activity in ventricular myocytes from male Fischer 344 rats

artículo científico publicado en 2008

The biology of frailty in humans and animals: Understanding frailty and promoting translation

artículo científico publicado en 2019

The effects of isoproterenol on abnormal electrical and contractile activity and diastolic calcium are attenuated in myocytes from aged Fischer 344 rats.

artículo científico publicado en 2007

The force-interval relation in aged hamster heart

artículo científico publicado en 1995

The impact of age and frailty on ventricular structure and function in C57BL/6J mice.

artículo científico publicado en 2017

The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart.

artículo científico publicado en 2013

The impact of pacemaker implantation on cognitive functioning in elderly patients

artículo científico publicado en 1992

The impacts of age and frailty on heart rate and sinoatrial node function

artículo científico publicado en 2016

Unblock of the slow inward current induces the arrhythmogenic transient inward current in isolated guinea-pig myocytes

artículo científico publicado en 1992

Use of Patient-Reported Symptoms from an Online Symptom Tracking Tool for Dementia Severity Staging: Development and Validation of a Machine Learning Approach

artículo científico publicado en 2020

[3H]-nitrendipine binding in normal and cardiomyopathic hamster hearts: Modulation by temperature, verapamil and diltiazem

artículo científico publicado en 1990

Lista de obras de Susan Howlett

"Voltage-activated Ca release" in rabbit, rat and guinea-pig cardiac myocytes, and modulation by internal cAMP.

3H-nitrendipine binding to hamster cardiac muscle homogenate

A Frailty Index Based on Common Laboratory Tests in Comparison With a Clinical Frailty Index for Older Adults in Long-Term Care Facilities

A clinical frailty index in aging mice: comparisons with frailty index data in humans

A frailty index based on laboratory deficits in community-dwelling men predicted their risk of adverse health outcomes

A procedure for creating a frailty index based on deficit accumulation in aging mice

Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart

Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging

Age and life expectancy clocks based on machine learning analysis of mouse frailty

Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion

Age-associated alterations in retinal arteriole reactivity to endothelin-1 differ between the sexes

Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats

Ageing: Develop models of frailty

Alterations in ventricular KATP channel properties during aging ⬇️

Animal models of frailty: current applications in clinical research

Assessment of Frailty in Animal Models

Associations between a laboratory frailty index and adverse health outcomes across age and sex

Attentuation of cardiac stunning by losartan in a cellular model of ischemia and reperfusion is accompanied by increased sarcoplasmic reticulum Ca2+ stores and prevention of cytosolic Ca2+ elevation

Beta-adrenoceptor stimulation exacerbates detrimental effects of ischemia and reperfusion in isolated guinea pig ventricular myocytes

Blood pressure in relation to age and frailty.

Calcium channels in normal and dystrophic hamster cardiac muscle. [3H]nitrendipine binding studies

Calcium currents in ventricular myocytes of prehypertrophic cardiomyopathic hamsters.

Calcium spark properties in ventricular myocytes are altered in aged mice

Calcium sparks in mouse ventricular myocytes at physiological temperature

Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature

Cardiac contraction, calcium transients, and myofilament calcium sensitivity fluctuate with the estrous cycle in young adult female mice.

Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice

Changes in excitation-contraction coupling in an isolated ventricular myocyte model of cardiac stunning

Characterization of membrane N-glycan binding sites of lysozyme for cardiac depression in sepsis.

Commentary: Age-related neurodegenerative disease research needs aging models

Contractile properties of myocardium are altered in dystrophin-deficient mdx mice

Contractions in guinea-pig ventricular myocytes triggered by a calcium-release mechanism separate from Na+ and L-currents

Contribution of a voltage-sensitive calcium release mechanism to contraction in cardiac ventricular myocytes.

Defective excitation-contraction coupling in hearts of rats with congestive heart failure

Deficient priming activity of newborn cord blood-derived polymorphonuclear neutrophilic granulocytes with lipopolysaccharide and tumor necrosis factor-alpha triggered with formyl-methionyl-leucyl-phenylalanine

Density of 1,4-dihydropyridine receptors decreases in the hearts of aging hamsters

Density of Ryanodine Receptors is Increased in Sarcoplasmic Reticulum from Prehypertrophic Cardiomyopathic Hamster Heart

Dibenzothiazepinones as potential calcium channel antagonists. I

Differential effects of phosphodiesterase-sensitive and -resistant analogs of cAMP on initiation of contraction in cardiac ventricular myocytes

Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes

Diminished Inotropic Response to Amrinone in Ventricular Myocytes from Myopathic Hamsters Is Linked to Depression of High-Gain Ca2+-Induced Ca2+ Release

Direct cloning of differential display products eluted from northern blots

Dysnatremia in Relation to Frailty and Age in Community-dwelling Adults in the National Health and Nutrition Examination Survey.

Effect of age on cardiac excitation-contraction coupling.

Effects of adenosine in simulated ischemia and reperfusion in guinea pig ventricular myocytes

Effects of ischemia and reperfusion on isolated ventricular myocytes from young adult and aged Fischer 344 rat hearts

Electrophysiologic differences between normal and dystrophic avian muscle

Factors that influence reliability of the mouse clinical frailty index

Force-interval relation in normal and cardiomyopathic hamster atria

Frailty: Scaling from Cellular Deficit Accumulation?

H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation.

Heterogeneity of Human Aging and Its Assessment

How cardiomyocyte excitation, calcium release and contraction become altered with age.

Hypothermia increases the gain of excitation-contraction coupling in guinea pig ventricular myocytes

Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

In Memoriam: Gregory R. Ferrier, PhD, 1943-2005.

In contrast to forskolin and 3-isobutyl-1-methylxanthine, amrinone stimulates the cardiac voltage-sensitive release mechanism without increasing calcium-induced calcium release.

Increased expression of the gene for alpha-interferon-inducible protein in cardiomyopathic hamster heart

Increases in diastolic [Ca2+] can contribute to positive inotropy in guinea pig ventricular myocytes in the absence of changes in amplitudes of Ca2+ transients

Ischemia and reperfusion injury following cardioplegic arrest is attenuated by age and testosterone deficiency in male but not female mice

L-Arginine ameliorates effects of ischemia and reperfusion in isolated cardiac myocytes

Lipid-lowering agents and the risk of cognitive impairment that does not meet criteria for dementia, in relation to apolipoprotein E status

Long-term testosterone deficiency modifies myofilament and calcium-handling proteins and promotes diastolic dysfunction in the aging mouse heart

Losartan exerts antiarrhythmic activity independent of angiotensin II receptor blockade in simulated ventricular ischemia and reperfusion.

Losartan improves recovery of contraction and inhibits transient inward current in a cellular model of cardiac ischemia and reperfusion.

Microbial shifts in the aging mouse gut.

Molecular geometries of dibenzothiazepinone and dibenzoxazepinone calcium antagonists

New horizons in frailty: ageing and the deficit-scaling problem

Novel cardioprotection strategies for the aged heart: evidence from pre-clinical studies

Orthostatic hypotension (OH) and mortality in relation to age, blood pressure and frailty

Ovariectomy enhances SR Ca²⁺ release and increases Ca²⁺ spark amplitudes in isolated ventricular myocytes

Overexpression of human beta2-adrenergic receptors increases gain of excitation-contraction coupling in mouse ventricular myocytes

Pediatric cardioplegia strategy results in enhanced calcium metabolism and lower serum troponin T.

Possible mechanisms underlying differences in force production between normal and cardiomyopathic hamster atria

Pretreatment with pinacidil promotes arrhythmias in an isolated tissue model of cardiac ischemia and reperfusion

Prevalence, Attributes, and Outcomes of Fitness and Frailty in Community-Dwelling Older Adults: Report From the Canadian Study of Health and Aging

Protecting the aged heart during cardiac surgery: The potential benefits of del Nido cardioplegia

Protein Kinase A-Mediated Phosphorylation Contributes to Enhanced Contraction Observed in Mice That Overexpress beta-Adrenergic Receptor Kinase-1

Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty