Lista de obras - Miriam Royo - Dominio Público Uruguay

A New Class of Foldamers Based oncis-γ-Amino-l-proline [J. Am. Chem. Soc.2004,126, 6048−6057]

scientific article published in 2005

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

artículo científico publicado en 2009

A new class of foldamers based on cis-gamma-amino-L-proline

artículo científico publicado en 2004

A novel protecting/activating strategy for beta-hydroxy acids and its use in convergent peptide synthesis

artículo científico publicado en 2008

A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.

artículo científico publicado en 2015

AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES

article by Fernando Albericio et al published January 2001 in Synthetic Communications

Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures

artículo científico publicado en 2011

Addressing the Tertiary Structure of Human Parathyroid Hormone-(1–34)

scientific article published in Journal of Biological Chemistry

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers

artículo científico publicado en 2009

Amphiphilic cationic carbosilane-PEG dendrimers: synthesis and applications in gene therapy.

artículo científico publicado en 2014

An Easy Entry to a New High-Symmetry, Large Molecular Framework for Molecular Recognition Studies and de Novo Protein Design. Solvent Modulation of the Spontaneous Formation of a Cyclic Monomer, Dimer, or Trimer from a Bis-cysteine Peptide

article by Miriam Royo et al published July 1998 in Journal of the American Chemical Society

An immunochemical strategy based on peptidoglycan synthetic peptide epitopes to diagnose Staphylococcus aureus infections.

artículo científico publicado en 2015

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

artículo científico publicado en 2014

Analysis of time-dependent conjugation of gold nanoparticles with an antiparkinsonian molecule by using curve resolution methods

scientific article published on 30 October 2010

Biocompatible, multifunctional, and well-defined OEG-based dendritic platforms for biomedical applications

scientific article published on 01 June 2013

Biotin Ergopeptide Probes for Dopamine Receptors ⬇️

artículo científico publicado el 31 de enero de 2011

Cell-penetrating cis-gamma-amino-l-proline-derived peptides.

artículo científico publicado en 2005

Combinatorial approaches towards the discovery of new tryptase inhibitors

artículo científico publicado en 2005

Competitive ELISA for N-terminal pro-brain natriuretic peptide (NT-proBNP) determination in human plasma

scientific article published on 20 August 2020

Controlling multivalency and multimodality: up to pentamodal dendritic platforms based on diethylenetriaminepentaacetic acid cores

artículo científico publicado en 2014

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription

artículo científico publicado en 2012

Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: a promising approach for the treatment of defective telomerase disorders.

artículo científico publicado en 2015

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

artículo científico publicado en 2009

Eco-friendly combination of the immobilized PGA enzyme and the S-Phacm protecting group for the synthesis of Cys-containing peptides

artículo científico publicado en 2012

Efficient γ-amino-proline-derived cell penetrating peptide–superparamagnetic iron oxide nanoparticle conjugates via aniline-catalyzed oxime chemistry as bimodal imaging nanoagents

artículo científico publicado en 2012

Engineering a Nanostructured Nucleolin-Binding Peptide for Intracellular Drug Delivery in Triple-Negative Breast Cancer Stem Cells

scientific article published on 21 January 2020

Environmental Effects Determine the Structure of Potential β-Amino Acid Based Foldamers

artículo científico publicado en 2018

Exploring solid-phase approaches for the preparation of new beta-lactams from amino acids.

artículo científico publicado en 2003

Gated Mesoporous Silica Nanoparticles Using a Double-Role Circular Peptide for the Controlled and Target-Preferential Release of Doxorubicin in CXCR4-Expresing Lymphoma Cells

Highly Versatile Polyelectrolyte Complexes for Improving the Enzyme Replacement Therapy of Lysosomal Storage Disorders

artículo científico publicado en 2016

Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors.

artículo científico publicado en 2009

Inhibition of VAP1: Quickly Gaining Ground as an Anti-Inflammatory Therapy

artículo científico publicado en 2007

Injectable Hyaluronan Hydrogels with Peptide-Binding Dendrimers Modulate the Controlled Release of BMP-2 and TGF-β1

artículo científico publicado en 2015

Kahalalide B. Synthesis of a natural cyclodepsipeptide

Multicomponent reactions with dihydroazines: efficient synthesis of a diverse set of pyrido-fused tetrahydroquinolines.

artículo científico publicado en 2005

Multivalent dendrimers presenting spatially controlled clusters of binding epitopes in thermoresponsive hyaluronan hydrogels

artículo científico publicado en 2014

N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate (TCFH), a powerful coupling reagent for bioconjugation

artículo científico publicado en 2008

Neurotoxicity of prion peptides mimicking the central domain of the cellular prion protein

artículo científico publicado en 2013

New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking

artículo científico publicado en 2006

Novel ergopeptides as dual ligands for adenosine and dopamine receptors

artículo científico publicado en 2007

Oral Insulin-Mimetic Compounds That Act Independently of Insulin

scientific article published on 01 February 2007

Peptide and amide bond-containing dendrimers

artículo científico publicado en 2005

Peptide dendrimers based on polyproline helices

artículo científico publicado en 2002

Phosphorylation of either Ser16 or Thr30 does not disrupt the structure of the Itch E3 ubiquitin ligase third WW domain

artículo científico publicado en 2005

Preparation of de novo globular proteins based on proline dendrimers

artículo científico publicado en 2005

Protein translation in Plasmodium parasites.

scientific article published on 07 July 2011

Radical Dendrimers Based on Biocompatible Oligoethylene Glycol Dendrimers as Contrast Agents for MRI

artículo científico publicado en 2020

S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis

S-Phenylacetamidomethyl (Phacm): an orthogonal cysteine protecting group for Boc and Fmoc solid-phase peptide synthesis strategies

Saturated resins or stress of the resin

Searching for new cell-penetrating agents: hybrid cyclobutane–proline γ,γ-peptides

artículo científico publicado en 2012

Selective inhibition of an apicoplastic aminoacyl-tRNA synthetase from Plasmodium falciparum.

artículo científico publicado en 2013

Solid-Phase Synthesis of Phenylalanine Containing Peptides Using a Traceless Triazene Linker

artículo científico publicado en 2012

Solid-phase combinatorial synthesis of a lysyl-tRNA synthetase (LysRS) inhibitory library

artículo científico publicado en 2008

Solid-phase combinatorial synthesis of peptide-biphenyl hybrids as calpain inhibitors

artículo científico publicado en 2004

Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins.

artículo científico publicado en 2009

Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade

artículo científico publicado en 2011

Solid-phase synthesis of chiral bicyclic guanidinium oligomers

artículo científico publicado en 2009

Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers.

artículo científico publicado en 2010

Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones

scientific article published on 05 March 2008

Solid-phase synthesis of second-generation polyproline dendrimers

artículo científico publicado en 2004

Solid-phase synthesis of sulfamate peptidomimetics

artículo científico publicado en 2007

Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels-Alder Type Additions

artículo científico publicado en 2018

Structure-activity relationship of kahalalide F synthetic analogues

artículo científico publicado en 2008

Synthesis and screening of a small library of proline-based biodendrimers for use as delivery agents

artículo científico publicado en 2005

Synthesis and structural study of highly constrained hybrid cyclobutane-proline γ,γ-peptides

artículo científico publicado en 2011

Synthesis and structure determination of kahalalide F (1,2).

artículo científico publicado en 2001

Synthesis of a 24-Membered Cyclic Peptide-Biphenyl Hybrid

Synthesis of peptides containing α, β-didehydroamino acids. Scope and limitations

TRPV1 modulators: structure-activity relationships using a rational combinatorial approach.

artículo científico publicado en 2011

Tentoxin as a scaffold for drug discovery. Total solid-phase synthesis of tentoxin and a library of analogues

artículo científico publicado en 2003

Triazene as a powerful tool for solid-phase derivatization of phenylalanine containing peptides: zygosporamide analogues as a proof of concept.

artículo científico publicado en 2014

Understanding the mechanism of action of the novel SSAO substrate (C7NH10)6(V10O28).2H2O, a prodrug of peroxovanadate insulin mimetics

artículo científico publicado en 2007

Undesired removal of the Fmoc group by the free ε-amino function of a lysine residue

Unequivocal synthesis and characterization of a parallel and an antiparallel bis-cystine peptide

Uteroglobin-like peptide cavities I. Synthesis of antiparallel and parallel dimers of bis-cysteine peptides

α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration

artículo científico publicado en 2016

Lista de obras de Miriam Royo

A New Class of Foldamers Based oncis-γ-Amino-l-proline [J. Am. Chem. Soc.2004,126, 6048−6057]

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

A new class of foldamers based on cis-gamma-amino-L-proline

A novel protecting/activating strategy for beta-hydroxy acids and its use in convergent peptide synthesis

A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.

AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES

Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures

Addressing the Tertiary Structure of Human Parathyroid Hormone-(1–34)

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers

Amphiphilic cationic carbosilane-PEG dendrimers: synthesis and applications in gene therapy.

An Easy Entry to a New High-Symmetry, Large Molecular Framework for Molecular Recognition Studies and de Novo Protein Design. Solvent Modulation of the Spontaneous Formation of a Cyclic Monomer, Dimer, or Trimer from a Bis-cysteine Peptide

An immunochemical strategy based on peptidoglycan synthetic peptide epitopes to diagnose Staphylococcus aureus infections.

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Analysis of time-dependent conjugation of gold nanoparticles with an antiparkinsonian molecule by using curve resolution methods

Biocompatible, multifunctional, and well-defined OEG-based dendritic platforms for biomedical applications

Biotin Ergopeptide Probes for Dopamine Receptors ⬇️

Cell-penetrating cis-gamma-amino-l-proline-derived peptides.

Combinatorial approaches towards the discovery of new tryptase inhibitors

Competitive ELISA for N-terminal pro-brain natriuretic peptide (NT-proBNP) determination in human plasma

Controlling multivalency and multimodality: up to pentamodal dendritic platforms based on diethylenetriaminepentaacetic acid cores

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription

Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: a promising approach for the treatment of defective telomerase disorders.

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

Eco-friendly combination of the immobilized PGA enzyme and the S-Phacm protecting group for the synthesis of Cys-containing peptides

Efficient γ-amino-proline-derived cell penetrating peptide–superparamagnetic iron oxide nanoparticle conjugates via aniline-catalyzed oxime chemistry as bimodal imaging nanoagents

Engineering a Nanostructured Nucleolin-Binding Peptide for Intracellular Drug Delivery in Triple-Negative Breast Cancer Stem Cells

Environmental Effects Determine the Structure of Potential β-Amino Acid Based Foldamers

Exploring solid-phase approaches for the preparation of new beta-lactams from amino acids.

Gated Mesoporous Silica Nanoparticles Using a Double-Role Circular Peptide for the Controlled and Target-Preferential Release of Doxorubicin in CXCR4-Expresing Lymphoma Cells

Highly Versatile Polyelectrolyte Complexes for Improving the Enzyme Replacement Therapy of Lysosomal Storage Disorders

Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors.

Inhibition of VAP1: Quickly Gaining Ground as an Anti-Inflammatory Therapy

Injectable Hyaluronan Hydrogels with Peptide-Binding Dendrimers Modulate the Controlled Release of BMP-2 and TGF-β1

Kahalalide B. Synthesis of a natural cyclodepsipeptide

Multicomponent reactions with dihydroazines: efficient synthesis of a diverse set of pyrido-fused tetrahydroquinolines.

Multivalent dendrimers presenting spatially controlled clusters of binding epitopes in thermoresponsive hyaluronan hydrogels

N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate (TCFH), a powerful coupling reagent for bioconjugation

Neurotoxicity of prion peptides mimicking the central domain of the cellular prion protein

New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking

Novel ergopeptides as dual ligands for adenosine and dopamine receptors

Oral Insulin-Mimetic Compounds That Act Independently of Insulin

Peptide and amide bond-containing dendrimers

Peptide dendrimers based on polyproline helices

Phosphorylation of either Ser16 or Thr30 does not disrupt the structure of the Itch E3 ubiquitin ligase third WW domain

Preparation of de novo globular proteins based on proline dendrimers

Protein translation in Plasmodium parasites.

Radical Dendrimers Based on Biocompatible Oligoethylene Glycol Dendrimers as Contrast Agents for MRI

S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis

S-Phenylacetamidomethyl (Phacm): an orthogonal cysteine protecting group for Boc and Fmoc solid-phase peptide synthesis strategies

Saturated resins or stress of the resin

Searching for new cell-penetrating agents: hybrid cyclobutane–proline γ,γ-peptides

Selective inhibition of an apicoplastic aminoacyl-tRNA synthetase from Plasmodium falciparum.

Solid-Phase Synthesis of Phenylalanine Containing Peptides Using a Traceless Triazene Linker

Solid-phase combinatorial synthesis of a lysyl-tRNA synthetase (LysRS) inhibitory library

Solid-phase combinatorial synthesis of peptide-biphenyl hybrids as calpain inhibitors

Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins.

Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade

Solid-phase synthesis of chiral bicyclic guanidinium oligomers

Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers.

Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones

Solid-phase synthesis of second-generation polyproline dendrimers

Solid-phase synthesis of sulfamate peptidomimetics

Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels-Alder Type Additions

Structure-activity relationship of kahalalide F synthetic analogues

Synthesis and screening of a small library of proline-based biodendrimers for use as delivery agents

Synthesis and structural study of highly constrained hybrid cyclobutane-proline γ,γ-peptides

Synthesis and structure determination of kahalalide F (1,2).

Synthesis of a 24-Membered Cyclic Peptide-Biphenyl Hybrid

Synthesis of peptides containing α, β-didehydroamino acids. Scope and limitations

TRPV1 modulators: structure-activity relationships using a rational combinatorial approach.

Tentoxin as a scaffold for drug discovery. Total solid-phase synthesis of tentoxin and a library of analogues

Triazene as a powerful tool for solid-phase derivatization of phenylalanine containing peptides: zygosporamide analogues as a proof of concept.

Understanding the mechanism of action of the novel SSAO substrate (C7NH10)6(V10O28).2H2O, a prodrug of peroxovanadate insulin mimetics

Undesired removal of the Fmoc group by the free ε-amino function of a lysine residue

Unequivocal synthesis and characterization of a parallel and an antiparallel bis-cystine peptide

Uteroglobin-like peptide cavities I. Synthesis of antiparallel and parallel dimers of bis-cysteine peptides

α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration