Lista de obras - Benjamin M. Segal - Dominio Público Uruguay

A new neutrophil subset promotes CNS neuron survival and axon regeneration

artículo científico publicado en 2020

A randomized, subject and rater-blinded, placebo-controlled trial of dimethyl fumarate for obstructive sleep apnea

scientific article published on 01 August 2018

Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2017: Environmental factors, genetics, and epigenetics in MS susceptibility and clinical course.

artículo científico publicado en 2018

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

scientific article published on 16 July 2018

An emerging role for eotaxins in neurodegenerative disease.

artículo científico publicado en 2016

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

artículo científico publicado en 1998

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

scientific article published on 08 July 2016

B-cell targeting agents in the treatment of multiple sclerosis.

artículo científico publicado en 2013

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis.

artículo científico publicado en 2017

CNS-resident classical DCs play a critical role in CNS autoimmune disease

scientific article published on 29 October 2018

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

artículo científico publicado en 2016

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

artículo científico publicado en 2009

Clinical trials in multiple sclerosis: potential future trial designs

scientific article published on 13 May 2019

Differences in diffusion tensor imaging-derived metrics in the corpus callosum of patients with multiple sclerosis without and with gadolinium-enhancing cerebral lesions

artículo científico publicado en 2012

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS.

artículo científico publicado en 2014

Enhancing natural killer cells is beneficial in multiple sclerosis - Commentary

scientific article published on 13 November 2018

Experimental autoimmune encephalomyelitis

artículo científico publicado en 2004

GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction

artículo científico publicado en 2017

GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.

artículo científico publicado en 2010

Getting to the crux of the matter: IL-23 and Th17 cell accumulation in the CNS.

artículo científico publicado en 2009

Highly polarized Th17 cells induce EAE via a T-bet independent mechanism

scientific article published on 23 August 2013

Hypnotic use and fatigue in multiple sclerosis.

artículo científico publicado en 2014

IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity

artículo científico publicado en 2003

IL-12 driven upregulation of P-selectin ligand on myelin-specific T cells is a critical step in an animal model of autoimmune demyelination

artículo científico publicado en 2006

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

artículo científico publicado en 2008

IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23.

artículo científico publicado en 2015

IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway ⬇️

artículo científico publicado el 15 de octubre de 2010

In vitro polarization of T-helper cells

artículo científico publicado en 2014

Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells

artículo científico publicado en 2005

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis

article

Modulation of the Innate Immune System: A Future Approach to the Treatment of Neurological Disease

artículo científico publicado en 2018

Multiple sclerosis relapse risk in the postoperative period: Effects of invasive surgery and anesthesia

artículo científico publicado en 2019

Myeloid cell plasticity in the evolution of central nervous system autoimmunity

artículo científico publicado en 2017

Natalizumab (Tysabri) ⬇️

artículo científico publicado el 5 de agosto de 2010

Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

artículo científico publicado en 2015

Neurosarcoidosis: diagnostic approaches and therapeutic strategies.

artículo científico

Neutrophil-related factors as biomarkers in EAE and MS.

artículo científico publicado en 2015

Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation

scientific article published on 07 November 2019

Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.

artículo científico publicado en 2013

Obstructive sleep apnea and fatigue in patients with multiple sclerosis.

artículo científico publicado en 2014

Obstructive sleep apnea is an under-recognized and consequential morbidity in multiple sclerosis

artículo científico publicado en 2014

Primary progressive multiple sclerosis--why we are failing

artículo científico publicado en 2016

Progressive decline in fractional anisotropy on serial DTI examinations of the corpus callosum: a putative marker of disease activity and progression in SPMS

artículo científico publicado en 2011

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis

artículo científico publicado en 2014

Stable biomarker for plastic microglia

artículo científico publicado en 2016

Stage-specific immune dysregulation in multiple sclerosis

artículo científico publicado en 2014

Sublime diagnosis of Lyme neuroborreliosis

scientific article published on 01 August 2005

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS.

artículo científico publicado en 2016

TH17 cytokines in autoimmune neuro-inflammation ⬇️

artículo científico publicado el 9 de septiembre de 2011

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

artículo científico publicado en 2015

Th1-mediated experimental autoimmune encephalomyelitis is CXCR3 independent

artículo científico publicado en 2013

Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune encephalomyelitis

artículo científico publicado en 2007

Th17 cells in autoimmune demyelinating disease.

artículo científico publicado en 2010

The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models

scientific article published on 19 January 2019

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

artículo científico publicado en 2008

The comeback of the elusive "suppressor" cell: an update on the regulatory network in EAE

artículo científico publicado en 1998

The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

artículo científico publicado en 1999

The dual roles of immunity in ALS: injury overrides protection.

artículo científico

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

scientific article published on 12 August 2019

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system ⬇️

artículo científico publicado el 8 de octubre de 2010

The role of natural killer cells in curbing neuroinflammation

artículo científico publicado en 2007

The straight talk on immune deviation

artículo científico publicado en 1998

The unwavering commitment of regulatory T cells in the suppression of autoimmune encephalomyelitis: another aspect of immune privilege in the CNS

artículo científico publicado en 2012

Treatment of CNS sarcoidosis with infliximab and mycophenolate mofetil

artículo científico publicado en 2009

Treatment of neuromyelitis optica spectrum disorders

artículo científico publicado en 2019

Underrecognition of sleep disorders in patients with multiple sclerosis

artículo científico publicado en 2015

Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: implications for how viral infections might trigger multiple sclerosis exacerbations

artículo científico publicado en 2013

Lista de obras de Benjamin M. Segal

A new neutrophil subset promotes CNS neuron survival and axon regeneration

A randomized, subject and rater-blinded, placebo-controlled trial of dimethyl fumarate for obstructive sleep apnea

Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2017: Environmental factors, genetics, and epigenetics in MS susceptibility and clinical course.

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

An emerging role for eotaxins in neurodegenerative disease.

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

B-cell targeting agents in the treatment of multiple sclerosis.

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis.

CNS-resident classical DCs play a critical role in CNS autoimmune disease

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

Clinical trials in multiple sclerosis: potential future trial designs

Differences in diffusion tensor imaging-derived metrics in the corpus callosum of patients with multiple sclerosis without and with gadolinium-enhancing cerebral lesions

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS.

Enhancing natural killer cells is beneficial in multiple sclerosis - Commentary

Experimental autoimmune encephalomyelitis

GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction

GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.

Getting to the crux of the matter: IL-23 and Th17 cell accumulation in the CNS.

Highly polarized Th17 cells induce EAE via a T-bet independent mechanism

Hypnotic use and fatigue in multiple sclerosis.

IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity

IL-12 driven upregulation of P-selectin ligand on myelin-specific T cells is a critical step in an animal model of autoimmune demyelination

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23.

IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway ⬇️

In vitro polarization of T-helper cells

Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis

Modulation of the Innate Immune System: A Future Approach to the Treatment of Neurological Disease

Multiple sclerosis relapse risk in the postoperative period: Effects of invasive surgery and anesthesia

Myeloid cell plasticity in the evolution of central nervous system autoimmunity

Natalizumab (Tysabri) ⬇️

Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

Neurosarcoidosis: diagnostic approaches and therapeutic strategies.

Neutrophil-related factors as biomarkers in EAE and MS.

Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation

Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.

Obstructive sleep apnea and fatigue in patients with multiple sclerosis.

Obstructive sleep apnea is an under-recognized and consequential morbidity in multiple sclerosis

Primary progressive multiple sclerosis--why we are failing

Progressive decline in fractional anisotropy on serial DTI examinations of the corpus callosum: a putative marker of disease activity and progression in SPMS

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis

Stable biomarker for plastic microglia

Stage-specific immune dysregulation in multiple sclerosis

Sublime diagnosis of Lyme neuroborreliosis

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS.

TH17 cytokines in autoimmune neuro-inflammation ⬇️

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

Th1-mediated experimental autoimmune encephalomyelitis is CXCR3 independent

Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune encephalomyelitis

Th17 cells in autoimmune demyelinating disease.

The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

The comeback of the elusive "suppressor" cell: an update on the regulatory network in EAE

The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

The dual roles of immunity in ALS: injury overrides protection.

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system ⬇️

The role of natural killer cells in curbing neuroinflammation

The straight talk on immune deviation

The unwavering commitment of regulatory T cells in the suppression of autoimmune encephalomyelitis: another aspect of immune privilege in the CNS

Treatment of CNS sarcoidosis with infliximab and mycophenolate mofetil

Treatment of neuromyelitis optica spectrum disorders

Underrecognition of sleep disorders in patients with multiple sclerosis

Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: implications for how viral infections might trigger multiple sclerosis exacerbations