Lista de obras - Thomas Pietschmann - Dominio Público Uruguay

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

scientific article published on 13 February 2019

A lymphotoxin-driven pathway to hepatocellular carcinoma

artículo científico publicado en 2009

A molecular tweezer antagonizes seminal amyloids and HIV infection.

artículo científico publicado en 2015

A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes

artículo científico publicado en 2012

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

artículo científico publicado en 2016

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors.

artículo científico publicado en 2010

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

artículo científico publicado en 2007

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

artículo científico publicado en 2014

Anti‐infective properties of epigallocatechin‐3‐gallate (EGCG), a component of green tea ⬇️

artículo científico publicado el 1 de marzo de 2013

Apolipoprotein E codetermines tissue tropism of hepatitis C virus and is crucial for viral cell-to-cell transmission by contributing to a postenvelopment step of assembly

artículo científico publicado en 2013

Apolipoprotein E polymorphisms and their protective effect on hepatitis E virus replication

artículo científico publicado en 2016

Bile acids specifically increase hepatitis C virus RNA-replication ⬇️

artículo científico publicado el 25 de abril de 2012

CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells.

artículo científico publicado en 2018

CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells

scientific journal article

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

artículo científico publicado en 2013

Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-Complementation

artículo científico publicado en 2009

Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment

artículo científico publicado en 2013

Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

artículo científico publicado en 2006

Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors

artículo científico publicado en 2019

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

artículo científico publicado en 2006

Characterization of the inhibition of hepatitis C virus entry by In vitro –generated and patient-derived oxidized low-density lipoprotein ⬇️

artículo científico publicado el 15 de febrero de 2013

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses

artículo científico publicado en 2015

Clinically Approved Ion Channel Inhibitors Close Gates for Hepatitis C Virus and Open Doors for Drug Repurposing in Infectious Viral Diseases.

artículo científico publicado en 2016

Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood

scientific article published on 01 August 2019

Cohort profile: The LoewenKIDS Study – life-course perspective on infections, the microbiome and the development of the immune system in early childhood

artículo científico publicado en 2019

Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

artículo científico publicado en 2011

Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.

artículo científico publicado en 2017

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

artículo científico publicado en 2006

Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons

artículo científico publicado en 2015

Correction for Haid et al., "Identification of a Human Respiratory Syncytial Virus Cell Entry Inhibitor by Using a Novel Lentiviral Pseudotype System"

artículo científico publicado en 2020

Decoding protein networks during virus entry by quantitative proteomics

artículo científico publicado en 2016

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

scientific article published on 24 April 2011

Efficient hepatitis C virus cell culture system: what a difference the host cell makes

artículo científico publicado en 2005

Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles

artículo científico publicado en 2008

Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus-induced interferon alpha responses of plasmacytoid dendritic cells

artículo científico publicado en 2014

Entry and replication of recombinant hepatitis C viruses in cell culture ⬇️

artículo científico publicado el 23 de septiembre de 2012

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

artículo científico publicado en 2011

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

artículo científico publicado en 2016

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

artículo científico publicado en 2015

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

artículo científico publicado en 2018

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

artículo científico publicado en 2015

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission

artículo científico publicado en 2016

Hepatitis C Virus

scientific article published on 29 January 2019

Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion

scientific article published on 03 February 2020

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner

artículo científico publicado en 2016

Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions.

artículo científico publicado en 2017

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

artículo científico publicado en 2007

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies

artículo científico publicado en 2020

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity.

artículo científico publicado en 2010

Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB

artículo científico publicado en 2018

Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.

artículo científico publicado en 2010

Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies

artículo científico publicado en 2014

Hepatitis C virus plays hide and seek with neutralizing antibodies.

artículo científico publicado en 2016

Hepatitis E virus replication and interferon responses in human placental cells.

artículo científico publicado en 2018

High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants

artículo científico publicado en 2012

Immune protection against reinfection with nonprimate hepacivirus.

artículo científico publicado en 2017

Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles ⬇️

artículo científico publicado el 1 de junio de 2011

Inactivation and survival of hepatitis C virus on inanimate surfaces

artículo científico publicado en 2011

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles.

artículo científico publicado en 2014

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

artículo científico publicado en 2013

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation

artículo científico publicado en 2015

Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7 ⬇️

artículo científico publicado en 2016

Labyrinthopeptins Exert Broad-Spectrum Antiviral Activity through Lipid-Binding-Mediated Virolysis

scientific article published on 06 January 2020

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

artículo científico publicado en 2020

Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles

artículo científico publicado en 2009

MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles

artículo científico publicado en 2012

Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity.

artículo científico publicado en 2017

Molecular characteristics and successful management of a respiratory syncytial virus outbreak among pediatric patients with hemato-oncological disease.

artículo científico publicado en 2018

Mouse-Specific Residues of Claudin-1 Limit Hepatitis C Virus Genotype 2a Infection in a Human Hepatocyte Cell Line

artículo científico publicado en 2010

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies

artículo científico publicado en 2012

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

artículo científico publicado en 2002

NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus

artículo científico publicado en 2010

Natural reservoirs for homologs of hepatitis C virus.

artículo científico publicado en 2014

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry

artículo científico publicado en 2017

Persicamidine – Außergewöhnliche Sesquarterpenoide mit potenter antiviraler Bioaktivität gegen Coronaviren

artículo científico publicado en 2023

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

artículo científico publicado en 2002

Personalized treatment of viral hepatitis of the present and the future : Hepatitis B, C, delta, and E

artículo científico publicado en 2017

Physicochemical Properties Govern the Activity of Potent Antiviral Flavones ⬇️

artículo científico publicado en 2019

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

artículo científico publicado en 2009

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

artículo científico publicado en 2005

Protein Interactions during the Flavivirus and Hepacivirus Life Cycle

artículo científico publicado en 2017

Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry

artículo científico publicado en 2015

Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins

artículo científico publicado en 2014

Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.

artículo científico publicado en 2007

Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses

artículo científico publicado en 2015

Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity

artículo científico publicado en 2015

Specific acquisition of functional CD59 but not CD46 or CD55 by hepatitis C virus

artículo científico publicado en 2012

Stability and transmission of hepatitis C virus in different anesthetic agents ⬇️

artículo científico publicado el 22 de marzo de 2013

Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly

artículo científico publicado en 2008

Subcellular localization and function of an epitope-tagged p7 viroporin in hepatitis C virus-producing cells

artículo científico publicado en 2012

Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents

artículo científico publicado en 2014

Synthesis of 4'/5'-Spirocyclopropanated Uridine and d-Xylouridine Derivatives and Their Activity against the Human Respiratory Syncytial Virus

scientific article published on 21 August 2019

Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

artículo científico publicado en 2015

The HCV life cycle: in vitro tissue culture systems and therapeutic targets.

artículo científico

The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells

artículo científico publicado en 2007

The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor

scientific article published on 24 October 2018

The novel immunosuppressive protein kinase C inhibitor sotrastaurin has no pro-viral effects on the replication cycle of hepatitis B or C virus

artículo científico publicado en 2011

The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination

artículo científico publicado en 2012

Tissue culture and animal models for hepatitis C virus

artículo científico publicado en 2003

Total synthesis of a noricumazole A library and evaluation of HCV inhibition

artículo científico publicado en 2012

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy.

artículo científico publicado en 2017

Transmission of Hepatitis C Virus Among People Who Inject Drugs: Viral Stability and Association With Drug Preparation Equipment ⬇️

artículo científico publicado el 5 de noviembre de 2012

Two methods of heterokaryon formation to discover HCV restriction factors

artículo científico publicado en 2012

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

artículo científico publicado en 2017

cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites

artículo científico publicado en 2016

hepatitis c Virus p7 is critical for capsid assembly and envelopment

artículo científico publicado en 2013

Lista de obras de Thomas Pietschmann

A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors

A lymphotoxin-driven pathway to hepatocellular carcinoma

A molecular tweezer antagonizes seminal amyloids and HIV infection.

A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors.

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

Anti‐infective properties of epigallocatechin‐3‐gallate (EGCG), a component of green tea ⬇️

Apolipoprotein E codetermines tissue tropism of hepatitis C virus and is crucial for viral cell-to-cell transmission by contributing to a postenvelopment step of assembly

Apolipoprotein E polymorphisms and their protective effect on hepatitis E virus replication

Bile acids specifically increase hepatitis C virus RNA-replication ⬇️

CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells.

CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-Complementation

Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment

Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

Characterization of the inhibition of hepatitis C virus entry by In vitro –generated and patient-derived oxidized low-density lipoprotein ⬇️

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses

Clinically Approved Ion Channel Inhibitors Close Gates for Hepatitis C Virus and Open Doors for Drug Repurposing in Infectious Viral Diseases.

Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood

Cohort profile: The LoewenKIDS Study – life-course perspective on infections, the microbiome and the development of the immune system in early childhood

Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons

Correction for Haid et al., "Identification of a Human Respiratory Syncytial Virus Cell Entry Inhibitor by Using a Novel Lentiviral Pseudotype System"

Decoding protein networks during virus entry by quantitative proteomics

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Efficient hepatitis C virus cell culture system: what a difference the host cell makes

Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles

Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus-induced interferon alpha responses of plasmacytoid dendritic cells

Entry and replication of recombinant hepatitis C viruses in cell culture ⬇️

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission

Hepatitis C Virus

Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner

Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions.

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity.

Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB

Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.

Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies

Hepatitis C virus plays hide and seek with neutralizing antibodies.

Hepatitis E virus replication and interferon responses in human placental cells.

High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants

Immune protection against reinfection with nonprimate hepacivirus.

Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles ⬇️

Inactivation and survival of hepatitis C virus on inanimate surfaces

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles.

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation

Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7 ⬇️

Labyrinthopeptins Exert Broad-Spectrum Antiviral Activity through Lipid-Binding-Mediated Virolysis

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles

MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles

Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity.

Molecular characteristics and successful management of a respiratory syncytial virus outbreak among pediatric patients with hemato-oncological disease.

Mouse-Specific Residues of Claudin-1 Limit Hepatitis C Virus Genotype 2a Infection in a Human Hepatocyte Cell Line

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus

Natural reservoirs for homologs of hepatitis C virus.

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry

Persicamidine – Außergewöhnliche Sesquarterpenoide mit potenter antiviraler Bioaktivität gegen Coronaviren

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

Personalized treatment of viral hepatitis of the present and the future : Hepatitis B, C, delta, and E

Physicochemical Properties Govern the Activity of Potent Antiviral Flavones ⬇️

Proceedings of the Frontiers of Retrovirology Conference 2016.