Lista de obras - Malin Parmar - Dominio Público Uruguay

3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

artículo científico publicado en 2020

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

scientific article published on 09 December 2019

A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population

artículo científico publicado en 2003

Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

artículo científico publicado en 2020

Advances in stem cell research and therapeutic development

artículo científico publicado en 2019

Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

artículo científico publicado en 2016

Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

artículo científico publicado en 2020

Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids

correction of a scholarly article

Brain repair and reprogramming: the route to clinical translation.

artículo científico publicado en 2016

Building authentic midbrain dopaminergic neurons from stem cells - lessons from development

artículo científico publicado en 2012

Cell-based therapies for Parkinson disease—past insights and future potential

artículo científico publicado en 2015

Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

scientific article published on 09 September 2018

Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015.

artículo científico publicado en 2016

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

artículo científico publicado en 2015

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.

artículo científico publicado en 2017

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

artículo científico publicado en 2016

Developing defined substrates for stem cell culture and differentiation.

artículo científico publicado en 2018

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

scientific journal article

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

artículo científico publicado en 2017

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

artículo científico publicado en 2017

Direct conversion of human fibroblasts to dopaminergic neurons ⬇️

artículo científico publicado en 2011

Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

artículo científico publicado en 2014

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

artículo científico publicado en 2017

Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.

artículo científico publicado en 2009

Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons

scientific article published on 10 October 2019

Early specification of dopaminergic phenotype during ES cell differentiation

artículo científico publicado en 2007

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

artículo científico publicado en 2012

Efficient induction of functional neurons from adult human fibroblasts

artículo científico publicado en 2011

Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation

scientific journal article

FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.

artículo científico publicado en 2010

From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

artículo científico publicado en 2020

GFORCE-PD still going strong in 2016.

artículo científico publicado en 2017

Generating regionalized neuronal cells from pluripotency, a step-by-step protocol

artículo científico publicado en 2012

Generation of Transplantable Striatal Projection Neurons from Human ESCs ⬇️

artículo científico publicado el 6 de abril de 2012

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation

artículo científico publicado en 2017

Generation of human cortical neurons from a new immortal fetal neural stem cell line.

artículo científico publicado en 2006

Generation of induced neurons via direct conversion in vivo

artículo científico publicado en 2013

Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions

artículo científico publicado en 2012

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.

artículo científico publicado en 2014

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease

artículo científico publicado en 2014

Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.

artículo científico publicado en 2017

Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.

artículo científico

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.

artículo científico publicado en 2017

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

artículo científico publicado en 2018

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

artículo científico publicado en 2017

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

artículo científico publicado en 2012

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

artículo científico publicado en 2020

In Vivo Reprogramming for Brain and Spinal Cord Repair

artículo científico publicado en 2015

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

artículo científico publicado en 2015

In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.

artículo científico publicado en 2007

Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.

artículo científico publicado en 2005

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

artículo científico publicado en 2014

Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts.

artículo científico publicado en 2011

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

scientific article published on 25 May 2020

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

artículo científico publicado en 2015

Neural grafting in Parkinson's disease Problems and possibilities

artículo científico publicado en 2010

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon

artículo científico publicado en 2006

New approaches for brain repair—from rescue to reprogramming

artículo científico publicado en 2018

Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

artículo científico publicado en 2006

Organization of the human embryonic ventral mesencephalon.

artículo científico publicado en 2009

Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro

artículo científico publicado en 2003

Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair

artículo científico publicado en 2016

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

artículo científico publicado en 2016

Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells

artículo científico publicado en 2019

Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

artículo científico publicado en 2020

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

artículo científico publicado en 2017

Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon

artículo científico publicado en 2002

Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies ⬇️

artículo científico publicado en 2018

Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2.

artículo científico publicado en 2008

Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum

artículo científico publicado en 2006

Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery

artículo científico publicado en 2022

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts.

artículo científico publicado en 2018

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

artículo científico publicado en 2020

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

artículo científico publicado en 2016

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

artículo científico publicado en 2019

Small molecules increase direct neural conversion of human fibroblasts

artículo científico publicado en 2016

Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

scientific article published on 01 March 2019

Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD).

artículo científico

Strengths and limitations of the neurosphere culture system

artículo científico publicado en 2006

Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.

artículo científico publicado en 2004

Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.

artículo científico publicado en 2017

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells

artículo científico publicado en 2017

Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

artículo científico publicado en 2018

Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

artículo científico publicado en 2017

The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansion.

artículo científico publicado en 2003

The future of stem cell therapies for Parkinson disease

artículo científico publicado en 2020

The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons

artículo científico publicado en 2013

Towards stem cell based therapies for Parkinson's disease

artículo científico publicado en 2018

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

artículo científico publicado en 2010

Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits

artículo científico publicado en 2020

Turning skin into dopamine neurons

artículo científico publicado en 2011

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease

scientific article published on 01 September 2019

hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation.

scientific article published on 25 May 2016

Lista de obras de Malin Parmar

3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population

Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

Advances in stem cell research and therapeutic development

Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids

Brain repair and reprogramming: the route to clinical translation.

Building authentic midbrain dopaminergic neurons from stem cells - lessons from development

Cell-based therapies for Parkinson disease—past insights and future potential

Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015.

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

Developing defined substrates for stem cell culture and differentiation.

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

Direct conversion of human fibroblasts to dopaminergic neurons ⬇️

Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.

Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons

Early specification of dopaminergic phenotype during ES cell differentiation

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

Efficient induction of functional neurons from adult human fibroblasts

Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation

FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.

From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

GFORCE-PD still going strong in 2016.

Generating regionalized neuronal cells from pluripotency, a step-by-step protocol

Generation of Transplantable Striatal Projection Neurons from Human ESCs ⬇️

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation

Generation of human cortical neurons from a new immortal fetal neural stem cell line.

Generation of induced neurons via direct conversion in vivo

Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease

Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.

Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

In Vivo Reprogramming for Brain and Spinal Cord Repair

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.

Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts.

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

Neural grafting in Parkinson's disease Problems and possibilities

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon

New approaches for brain repair—from rescue to reprogramming

Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

Organization of the human embryonic ventral mesencephalon.

Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro

Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells

Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon

Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies ⬇️

Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2.

Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum

Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts.

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Small molecules increase direct neural conversion of human fibroblasts

Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD).

Strengths and limitations of the neurosphere culture system