Lista de obras - Michael J. Kelso - Dominio Público Uruguay

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor

artículo científico publicado en 2016

6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

scientific article published on 07 September 2018

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

artículo científico publicado en 2003

A comparison of patient matched meibum and tear lipidomes.

artículo científico publicado en 2013

A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives

artículo científico publicado en 2010

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

artículo científico publicado en 2000

Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

artículo científico publicado en 2011

Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo.

artículo científico publicado en 2018

Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo

artículo científico publicado en 2017

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

artículo científico publicado en 2015

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components

artículo científico publicado en 2010

Catalytic enantioselective conjugate addition of carbamates

artículo científico publicado en 2004

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

artículo científico publicado en 2017

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

article

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

artículo científico publicado en 2017

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

artículo científico publicado en 2020

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

artículo científico publicado en 2014

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

artículo científico publicado en 2002

Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]

artículo científico publicado en 2019

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens

artículo científico publicado en 2018

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

artículo científico publicado en 2014

Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry.

artículo científico publicado en 2016

Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells

artículo científico publicado en 2013

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

artículo científico publicado en 2014

Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

scientific article published on 25 July 2019

Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation

artículo científico publicado en 2008

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

artículo científico publicado en 2017

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (-acyl)-ω-hydroxy fatty acids

scientific article published on 15 June 2018

Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids

artículo científico publicado en 2001

On the stability of a single-turn alpha-helix: the single versus multiconformation problem

artículo científico publicado en 2003

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation

artículo científico publicado en 2017

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2018

Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study

artículo científico publicado en 2019

Roles of the Na+/H+ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion

artículo científico publicado en 2021

Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.

artículo científico publicado en 2011

Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes

artículo científico publicado en 2012

Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp

artículo científico publicado en 2013

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

artículo científico publicado en 2008

Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase

artículo científico publicado en 2007

Synthesis and preliminary evaluation of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones as angiogenesis inhibitors

artículo científico publicado en 2016

Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)

artículo científico publicado en 2011

Synthesis of Berberine-Efflux Pump Inhibitor Hybrid Antibacterials.

artículo científico publicado en 2010

Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

artículo científico publicado en 2013

Virulence profile: Mike Kelso

artículo científico publicado en 2017

Lista de obras de Michael J. Kelso

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor

6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

A comparison of patient matched meibum and tear lipidomes.

A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo.

Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components

Catalytic enantioselective conjugate addition of carbamates

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry.

Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (-acyl)-ω-hydroxy fatty acids

Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids

On the stability of a single-turn alpha-helix: the single versus multiconformation problem

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus

Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study

Roles of the Na+/H+ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion

Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.

Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes

Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase

Synthesis and preliminary evaluation of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones as angiogenesis inhibitors

Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)

Synthesis of Berberine-Efflux Pump Inhibitor Hybrid Antibacterials.

Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

Virulence profile: Mike Kelso