Lista de obras - Stephen C. Harmer - Dominio Público Uruguay

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.

artículo científico publicado en 2013

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

artículo científico publicado en 2017

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

artículo científico publicado en 2018

Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1.

artículo científico publicado en 2014

Characterization of a binding site for anionic phospholipids on KCNQ1.

artículo científico publicado en 2010

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

artículo científico publicado en 2016

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

artículo científico publicado en 2017

Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function

artículo científico publicado en 2019

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

artículo científico publicado en 2015

Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

artículo científico publicado en 2021

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

artículo científico publicado en 2019

K+ channels in the heart: new insights and therapeutic implications

artículo científico publicado en 2010

Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?

artículo científico publicado en 2008

Mechanisms of disease pathogenesis in long QT syndrome type 5

artículo científico publicado en 2009

Molecular mechanisms of congenital hyperinsulinism due to autosomal dominant mutations in ABCC8.

artículo científico publicado en 2015

Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking

artículo científico publicado en 2017

Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths

artículo científico publicado en 2018

Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel.

artículo científico publicado en 2012

The control of cardiac ventricular excitability by autonomic pathways.

artículo científico publicado en 2017

The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes.

artículo científico publicado en 2016

The role of abnormal trafficking of KCNE1 in long QT syndrome 5.

artículo científico publicado en 2007

The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal

scientific article published on 01 November 2004

Lista de obras de Stephen C. Harmer

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1.

Characterization of a binding site for anionic phospholipids on KCNQ1.

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

K+ channels in the heart: new insights and therapeutic implications

Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?

Mechanisms of disease pathogenesis in long QT syndrome type 5

Molecular mechanisms of congenital hyperinsulinism due to autosomal dominant mutations in ABCC8.

Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking

Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths

Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel.

The control of cardiac ventricular excitability by autonomic pathways.

The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes.

The role of abnormal trafficking of KCNE1 in long QT syndrome 5.

The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal