Lista de obras - Gregg E. Homanics - Dominio Público Uruguay

A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development

artículo científico publicado en 2021

A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse

artículo científico publicado en 2005

A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol

artículo científico publicado en 2006

A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity

artículo científico publicado en 2021

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

artículo científico publicado en 2010

Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury.

artículo científico publicado en 2009

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

artículo científico publicado en 2010

Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury

artículo científico publicado en 2006

Alcohol-induced tolerance and physical dependence in mice with ethanol insensitive alpha1 GABA A receptors.

artículo científico publicado en 2008

Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear

artículo científico publicado en 2005

Alterations in ethanol-induced behaviors and consumption in knock-in mice expressing ethanol-resistant NMDA receptors

artículo científico publicado en 2013

Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit

artículo científico publicado en 2009

Altered atypical coupling of gamma-aminobutyrate type A receptor agonist and convulsant binding sites in subunit-deficient mouse lines.

artículo científico publicado en 2001

Altered localization of the δ subunit of the GABAA receptor in the thalamus of α4 subunit knockout mice

artículo científico publicado en 2013

Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.

artículo científico publicado en 2002

Altered sedative effects of ethanol in mice with α1 glycine receptor subunits that are insensitive to Gβγ modulation

scientific journal article

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice

artículo científico publicado en 2006

Anesthesia Sensitivity in Mice that Lack the β3 Subunit of the γ-Aminobutyric Acid Type A Receptor ⬇️

artículo científico publicado el 1 de marzo de 1998

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

artículo científico publicado en 1999

Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.

artículo científico publicado en 2011

Brain regional heterogeneity of pH effects on GABA(A) receptor-associated [35s]TBPS binding

artículo científico publicado en 2004

Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.

artículo científico publicado en 2011

Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity

artículo científico publicado en 2010

Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.

artículo científico publicado en 2011

Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice.

artículo científico publicado en 2006

Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.

artículo científico publicado en 2003

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.

artículo científico publicado en 2007

Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice

artículo científico publicado en 2006

Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease

artículo científico publicado en 2009

Effect of embryonic knock-down of GABAA receptors on the levels of monoamines and their metabolites in the CNS of the mouse

artículo científico publicado en 2001

Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane

artículo científico publicado en 2007

Effects of Paternal Preconception Vapor Alcohol Exposure Paradigms on Behavioral Responses in Offspring

scientific article published on 22 September 2020

Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus

artículo científico publicado en 2008

Exencephaly and hydrocephaly in mice with targeted modification of the Apolipoprotein B (Apob) gene

article

Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells

artículo científico publicado en 2007

Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.

artículo científico publicado en 2006

GABA influences the development of the ventromedial nucleus of the hypothalamus.

artículo científico publicado en 2001

GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

artículo científico publicado en 2002

GABA(A) receptor beta3 subunit deletion decreases alpha2/3 subunits and IPSC duration

artículo científico publicado en 2003

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain

artículo científico publicado en 2002

GABA(A) receptor delta subunit deletion prevents neurosteroid modulation of inhibitory synaptic currents in cerebellar neurons.

artículo científico publicado en 2002

GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice

artículo científico publicado en 2006

GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

scientific journal article

GABAA receptor beta3 subunit gene-deficient heterozygous mice show parent-of-origin and gender-related differences in beta3 subunit levels, EEG, and behavior

artículo científico publicado en 2005

GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.

artículo científico publicado en 2005

GABAA-R α4 subunits are required for the low dose locomotor stimulatory effect of alphaxalone, but not for several other behavioral responses to alphaxalone, etomidate or propofol

artículo científico publicado en 2013

Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder

artículo científico publicado en 2008

Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.

scientific article published on 03 August 2011

Gene-edited CRISPy Critters for alcohol research

scientific article published on 07 March 2018

Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.

artículo científico publicado en 2016

Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice.

artículo científico publicado en 2005

Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research.

artículo científico publicado en 2014

Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).

artículo científico publicado en 2009

Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease

artículo científico publicado en 2009

Hypoplasia of spiral and Scarpa's ganglion cells in GABA(A) receptor beta(3) subunit knockout mice.

artículo científico publicado en 2002

Increased acute cocaine sensitivity and decreased cocaine sensitization in GABA(A) receptor beta3 subunit knockout mice

artículo científico publicado en 1999

Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors

artículo científico publicado en 2009

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

artículo científico publicado en 2003

Intergenerational Effects of Alcohol: A Review of Paternal Preconception Ethanol Exposure Studies and Epigenetic Mechanisms in the Male Germline

artículo científico publicado en 2019

Investigation of ethanol-induced impairment of spatial memory in gamma2 heterozygous knockout mice.

artículo científico publicado en 2009

Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of alpha1-subunit-deficient mice.

artículo científico publicado en 2005

Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

artículo científico publicado en 2008

Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol

artículo científico publicado en 2006

Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty.

artículo científico publicado en 2012

Lack of CaV3.1 channels causes severe motor coordination defects and an age-dependent cerebellar atrophy in a genetic model of essential tremor

artículo científico publicado en 2011

Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication.

artículo científico publicado en 2012

Long-term effects of diazepam treatment of epileptic GABAA receptor beta3 subunit knockout mouse in early life

artículo científico publicado en 2005

Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors.

artículo científico publicado en 2010

MAP2 is differentially phosphorylated in schizophrenia, altering its function

artículo científico publicado en 2021

Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol.

artículo científico publicado en 2010

Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines

artículo científico publicado en 2000

Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks

artículo científico publicado en 2008

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

artículo científico publicado en 1995

Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice

artículo científico publicado en 2002

Mouse models of Angelman syndrome, a neurodevelopmental disorder, display different brain regional GABA(A) receptor alterations

artículo científico publicado en 2003

Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination

artículo científico publicado en 2017

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice

artículo científico publicado en 2012

New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout

artículo científico publicado en 2007

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.

artículo científico publicado en 1999

Paternal Preconception Every-Other-Day Ethanol Drinking Alters Behavior and Ethanol Consumption in Offspring

artículo científico publicado en 2019

Paternal preconception alcohol exposure imparts intergenerational alcohol-related behaviors to male offspring on a pure C57BL/6J background

artículo científico publicado en 2016

Paternal preconception ethanol exposure blunts hypothalamic-pituitary-adrenal axis responsivity and stress-induced excessive fluid intake in male mice.

artículo científico publicado en 2016

Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting

scientific article published on 26 October 2013

Pharmacologic and behavioral responses of inbred C57BL/6J and strain 129/SvJ mouse lines

artículo científico publicado en 1999

Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome

artículo científico publicado en 2005

Pre- and postsynaptic GABA receptors at reciprocal dendrodendritic synapses in the olfactory bulb.

artículo científico publicado en 2004

Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.

artículo científico publicado en 2014

Production and characterization of murine models of classic and intermediate maple syrup urine disease

artículo científico publicado en 2006

Production of conditional point mutant knockin mice

scientific article published on 01 July 2006

Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.

artículo científico publicado en 2009

Reciprocal inhibitory connections and network synchrony in the mammalian thalamus

artículo científico publicado en 1999

Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit

artículo científico publicado en 2003

Reduced sedation and increased ethanol consumption in knock-in mice expressing an ethanol insensitive alpha 2 subunit of the glycine receptor

artículo científico publicado en 2020

Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor.

artículo científico publicado en 2000

Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor

artículo científico publicado en 2002

Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder

artículo científico publicado en 2005

Subunit Compensation and Plasticity of Synaptic GABAA Receptors Induced by Ethanol in ?4 Subunit Knockout Mice ⬇️

artículo científico publicado el 23 de septiembre de 2011

T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor.

artículo científico publicado en 2010

Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer

artículo científico publicado en 2013

Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells

scientific journal article

Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus. ⬇️

artículo científico publicado en 2008

Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice.

artículo científico publicado en 2010

The EEG effects of THIP (Gaboxadol) on sleep and waking are mediated by the GABA(A)delta-subunit-containing receptors

artículo científico publicado en 2007

The alpha1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala

artículo científico publicado en 2009

The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells.

artículo científico publicado en 2007

The neutral cysteine protease bleomycin hydrolase is essential for epidermal integrity and bleomycin resistance

scientific journal article

Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation

artículo científico publicado en 2013

Tonic for what ails us? high-affinity GABAA receptors and alcohol

artículo científico publicado en 2007

Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors.

artículo científico publicado en 2006

delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol

artículo científico publicado en 2006

Lista de obras de Gregg E. Homanics

A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development

A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse

A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol

A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury.

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury

Alcohol-induced tolerance and physical dependence in mice with ethanol insensitive alpha1 GABA A receptors.

Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear

Alterations in ethanol-induced behaviors and consumption in knock-in mice expressing ethanol-resistant NMDA receptors

Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit

Altered atypical coupling of gamma-aminobutyrate type A receptor agonist and convulsant binding sites in subunit-deficient mouse lines.

Altered localization of the δ subunit of the GABAA receptor in the thalamus of α4 subunit knockout mice

Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.

Altered sedative effects of ethanol in mice with α1 glycine receptor subunits that are insensitive to Gβγ modulation

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice

Anesthesia Sensitivity in Mice that Lack the β3 Subunit of the γ-Aminobutyric Acid Type A Receptor ⬇️

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.

Brain regional heterogeneity of pH effects on GABA(A) receptor-associated [35s]TBPS binding

Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.

Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity

Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.

Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice.

Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.

Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice

Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease

Effect of embryonic knock-down of GABAA receptors on the levels of monoamines and their metabolites in the CNS of the mouse

Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane

Effects of Paternal Preconception Vapor Alcohol Exposure Paradigms on Behavioral Responses in Offspring

Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus

Exencephaly and hydrocephaly in mice with targeted modification of the Apolipoprotein B (Apob) gene

Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells

Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.

GABA influences the development of the ventromedial nucleus of the hypothalamus.

GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

GABA(A) receptor beta3 subunit deletion decreases alpha2/3 subunits and IPSC duration

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain

GABA(A) receptor delta subunit deletion prevents neurosteroid modulation of inhibitory synaptic currents in cerebellar neurons.

GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice

GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

GABAA receptor beta3 subunit gene-deficient heterozygous mice show parent-of-origin and gender-related differences in beta3 subunit levels, EEG, and behavior

GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.

GABAA-R α4 subunits are required for the low dose locomotor stimulatory effect of alphaxalone, but not for several other behavioral responses to alphaxalone, etomidate or propofol

Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder

Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.

Gene-edited CRISPy Critters for alcohol research

Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.

Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice.

Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research.

Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).

Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease

Hypoplasia of spiral and Scarpa's ganglion cells in GABA(A) receptor beta(3) subunit knockout mice.

Increased acute cocaine sensitivity and decreased cocaine sensitization in GABA(A) receptor beta3 subunit knockout mice

Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

Intergenerational Effects of Alcohol: A Review of Paternal Preconception Ethanol Exposure Studies and Epigenetic Mechanisms in the Male Germline

Investigation of ethanol-induced impairment of spatial memory in gamma2 heterozygous knockout mice.

Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of alpha1-subunit-deficient mice.

Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol

Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty.

Lack of CaV3.1 channels causes severe motor coordination defects and an age-dependent cerebellar atrophy in a genetic model of essential tremor

Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication.

Long-term effects of diazepam treatment of epileptic GABAA receptor beta3 subunit knockout mouse in early life

Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors.

MAP2 is differentially phosphorylated in schizophrenia, altering its function

Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol.

Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines

Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice

Mouse models of Angelman syndrome, a neurodevelopmental disorder, display different brain regional GABA(A) receptor alterations

Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice

New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.