Lista de obras - Carmen Guerra - Dominio Público Uruguay

A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition

artículo científico publicado en 2008

A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

artículo científico publicado en 2010

Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation

artículo científico publicado en 1998

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

artículo científico publicado en 2007

Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells

artículo científico publicado en 2016

Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis.

artículo científico publicado en 2017

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

scientific article published on 08 April 2019

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

artículo científico publicado en 2010

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

artículo científico publicado en 2012

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity ⬇️

artículo científico publicado el 15 de julio de 1998

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

artículo científico publicado en 2011

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

artículo científico publicado en 2014

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

artículo científico publicado en 2010

Genetically Engineered Mouse Models of K-Ras-Driven Lung and Pancreatic Tumors: Validation of Therapeutic Targets

scientific article published on 01 May 2018

Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome

artículo científico publicado en 2008

H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences

artículo científico publicado en 2016

IGF-I induces the uncoupling protein gene expression in fetal rat brown adipocyte primary cultures: role of C/EBP transcription factors.

artículo científico publicado en 1994

K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.

artículo científico publicado en 2016

K-RasV14I recapitulates Noonan syndrome in mice

artículo científico publicado en 2014

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo

artículo científico publicado en 2006

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

artículo científico publicado en 2015

Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models

artículo científico publicado en 2017

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

scientific journal article

Modeling RASopathies with Genetically Modified Mouse Models.

artículo científico publicado en 2017

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice

artículo científico publicado en 2014

Noonan syndrome: lessons learned from genetically modified mouse models

artículo científico publicado en 2017

Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis

scientific article published on 21 June 2019

Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence

artículo científico publicado en 2011

Parp-1genetic ablation inEla-mycmice unveils novel roles for Parp-1 in pancreatic cancer

scientific article published on 04 August 2014

Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.

artículo científico publicado en 2010

Reply: 'Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'.

artículo científico publicado en 2014

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

artículo científico publicado en 2018

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.

artículo científico publicado en 2018

The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice

artículo científico publicado en 2015

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma

artículo científico publicado en 2009

The impact of the genetic background in the Noonan syndrome phenotype induced by K-Ras(V14I).

artículo científico publicado en 2015

Triiodothyronine Induces the Transcription of the Uncoupling Protein Gene and Stabilizes Its mRNA in Fetal Rat Brown Adipocyte Primary Cultures

artículo científico publicado en 1996

Triiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expression

article

Triiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expression

artículo científico publicado en 1994

Tumour biology: senescence in premalignant tumours

artículo científico publicado en 2005

Upregulation of miR-21 by Ras in vivo and its role in tumor growth.

artículo científico publicado en 2010

Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models

artículo científico publicado en 2014

What we have learned about pancreatic cancer from mouse models.

artículo científico

c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling.

artículo científico publicado en 2018

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

scientific article published on 29 April 2007

Lista de obras de Carmen Guerra

A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition

A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells

Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis.

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity ⬇️

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

Genetically Engineered Mouse Models of K-Ras-Driven Lung and Pancreatic Tumors: Validation of Therapeutic Targets

Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome

H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences

IGF-I induces the uncoupling protein gene expression in fetal rat brown adipocyte primary cultures: role of C/EBP transcription factors.

K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.

K-RasV14I recapitulates Noonan syndrome in mice

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo

Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression

Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Modeling RASopathies with Genetically Modified Mouse Models.

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice

Noonan syndrome: lessons learned from genetically modified mouse models

Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis

Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence

Parp-1genetic ablation inEla-mycmice unveils novel roles for Parp-1 in pancreatic cancer

Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.

Reply: 'Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'.

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.

The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma

The impact of the genetic background in the Noonan syndrome phenotype induced by K-Ras(V14I).

Triiodothyronine Induces the Transcription of the Uncoupling Protein Gene and Stabilizes Its mRNA in Fetal Rat Brown Adipocyte Primary Cultures

Triiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expression

Triiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expression

Tumour biology: senescence in premalignant tumours

Upregulation of miR-21 by Ras in vivo and its role in tumor growth.

Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models

What we have learned about pancreatic cancer from mouse models.

c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling.

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation