Lista de obras - Angelika Lampert - Dominio Público Uruguay

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

artículo científico publicado en 2008

Activating mutation of the renal epithelial chloride channel ClC-Kb, predisposing to hypertension

artículo científico publicado en 2004

Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents.

artículo científico publicado en 2014

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na V 1.6-resurgent and persistent current ⬇️

artículo científico publicado el 9 de abril de 2012

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel

artículo científico publicado en 2012

C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability.

artículo científico publicado en 2015

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli

artículo científico publicado en 2014

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

artículo científico publicado en 2012

Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor.

artículo científico publicado en 2016

DIsulfide Mapping PLanner Software Tool

artículo científico publicado en 2017

Dataset of electrophysiological patch-clamp recordings of the effect of the compounds deltamethrin, ATx-II and β4-peptide on human cardiac Nav1.5 sodium channel gating properties

artículo científico publicado en 2020

Deranged Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible kinase SGK1.

artículo científico publicado en 2005

Differential axonal conduction patterns of mechano-sensitive and mechano-insensitive nociceptors--a combined experimental and modelling study.

artículo científico publicado en 2014

Differential roles of S6 domain hinges in the gating of KCNQ potassium channels.

artículo científico publicado en 2005

Effect of dexamethasone on voltage-gated K + channels in Jurkat T-lymphocytes

artículo científico publicado en 2003

Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials.

artículo científico publicado en 2009

Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7.

artículo científico publicado en 2015

Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner

artículo científico publicado en 2019

Functional expression of nicotinic acetylcholine receptors in rat neocortical layer 5 pyramidal cells

artículo científico publicado en 2008

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model

scientific article published on 11 March 2016

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

scientific article published on 30 December 2013

Germs against pain: Humanized bacterial sodium channels

artículo científico publicado en 2016

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

artículo científico publicado en 2014

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors

scientific article published on 25 August 2019

Influence of gain of function epithelial chloride channel ClC-Kb mutation on hearing thresholds

artículo científico publicado en 2006

Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.

artículo científico publicado en 2013

Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation

artículo científico publicado en 2011

Markov modeling of ion channels: implications for understanding disease

artículo científico

Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors

artículo científico publicado en 2013

Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine.

artículo científico publicado en 2017

Noncanonical Ion Channel Behaviour in Pain

scientific article published on 15 September 2019

Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors

artículo científico publicado en 2015

Resurgent currents turn painfully exciting.

scientific article published on February 2011

Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis.

artículo científico publicado en 2008

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.

artículo científico publicado en 2016

Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?

artículo científico publicado en 2013

Sodium channel slow inactivation interferes with open channel block

artículo científico publicado en 2016

Sodium channelopathies and pain

scientific article published on 26 January 2010

Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7

artículo científico publicado en 2007

The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5.

artículo científico publicado en 2013

The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.

artículo científico publicado en 2013

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.

artículo científico publicado en 2014

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients

scientific article published on 01 June 2019

Thyrotropin serum concentrations in healthy volunteers are associated with depression-related personality traits.

artículo científico publicado en 2007

Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.

artículo científico publicado en 2018

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

artículo científico publicado en 2006

β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5.

artículo científico publicado en 2019

β1 subunit stabilises sodium channel Nav1.7 against mechanical stress.

artículo científico publicado en 2018

Lista de obras de Angelika Lampert

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

Activating mutation of the renal epithelial chloride channel ClC-Kb, predisposing to hypertension

Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents.

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na V 1.6-resurgent and persistent current ⬇️

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel

C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability.

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor.

DIsulfide Mapping PLanner Software Tool

Dataset of electrophysiological patch-clamp recordings of the effect of the compounds deltamethrin, ATx-II and β4-peptide on human cardiac Nav1.5 sodium channel gating properties

Deranged Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible kinase SGK1.

Differential axonal conduction patterns of mechano-sensitive and mechano-insensitive nociceptors--a combined experimental and modelling study.

Differential roles of S6 domain hinges in the gating of KCNQ potassium channels.

Effect of dexamethasone on voltage-gated K + channels in Jurkat T-lymphocytes

Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials.

Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7.

Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner

Functional expression of nicotinic acetylcholine receptors in rat neocortical layer 5 pyramidal cells

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

Germs against pain: Humanized bacterial sodium channels

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors

Influence of gain of function epithelial chloride channel ClC-Kb mutation on hearing thresholds

Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.

Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation

Markov modeling of ion channels: implications for understanding disease

Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors

Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine.

Noncanonical Ion Channel Behaviour in Pain

Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors

Resurgent currents turn painfully exciting.

Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis.

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.

Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?

Sodium channel slow inactivation interferes with open channel block

Sodium channelopathies and pain

Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7

The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5.

The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients

Thyrotropin serum concentrations in healthy volunteers are associated with depression-related personality traits.

Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5.

β1 subunit stabilises sodium channel Nav1.7 against mechanical stress.