Lista de obras - Takamasa Ueno - Dominio Público Uruguay

A phase I trial of the pharmacokinetics, toxicity, and activity of KNI-272, an inhibitor of HIV-1 protease, in patients with AIDS or symptomatic HIV infection

artículo científico publicado en 1999

A recurrent large Alu-mediated deletion in the hypoxanthine phosphoribosyltransferase (HPRT1) gene associated with Lesch-Nyhan syndrome.

artículo científico publicado en 2001

A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion

artículo científico publicado en 2015

Aromatic Side Chain at Position 412 of SERINC5 Exerts Restriction Activity toward HIV-1 and Other Retroviruses

artículo científico publicado en 2021

Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection

artículo científico publicado en 2015

Attenuation of multiple Nef functions in HIV-1 elite controllers

artículo científico publicado en 2013

CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope

artículo científico publicado en 2013

CTL-Mediated Selective Pressure Influences Dynamic Evolution and Pathogenic Functions of HIV-1 Nef

article

Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross-reactivity.

artículo científico publicado en 2015

Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay

artículo científico publicado en 1997

Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR.

artículo científico publicado en 2017

Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths.

artículo científico publicado en 2013

Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope

artículo científico publicado en 2008

Development of fluoroquinolone resistance and mutations involving GyrA and ParC proteins among Neisseria gonorrhoeae isolates in Japan

scientific article published on 01 June 1998

Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.

artículo científico publicado en 2010

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

artículo científico publicado en 2015

Domain structures of the MS ring component protein (FliF) of the flagellar basal body of Salmonella typhimurium.

artículo científico publicado en 1994

Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection ⬇️

artículo científico publicado el 7 de julio de 2010

Dynamic range of Nef functions in chronic HIV-1 infection

artículo científico publicado en 2013

Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection

artículo científico publicado en 2015

Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.

artículo científico publicado en 2009

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages.

artículo científico publicado en 2011

Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

artículo científico publicado en 1995

Failure of effector function of human CD8+ T Cells in NOD/SCID/JAK3⁻/⁻ immunodeficient mice transplanted with human CD34+ hematopoietic stem cells

artículo científico publicado en 2010

Flagellar filament elongation can be impaired by mutations in the hook protein FlgE of Salmonella typhimurium: a possible role of the hook as a passage for the anti-sigma factor FlgM.

artículo científico publicado en 1998

Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions.

artículo científico publicado en 2004

HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations.

artículo científico publicado en 2017

HLA class I-restricted recognition of an HIV-derived epitope peptide by a human T cell receptor alpha chain having a Vdelta1 variable segment.

artículo científico publicado en 2003

Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.

artículo científico publicado en 2016

Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral activity of HIV-specific CTL.

artículo científico publicado en 2009

Impaired Nef function is associated with early control of HIV-1 viremia

artículo científico publicado en 2014

Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.

artículo científico publicado en 2002

Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety

artículo científico publicado en 2000

Inhibition of telomerase by linear-chain fatty acids: a structural analysis.

artículo científico publicado en 2002

Inhibition of the hepatitis C virus NS3 protease activity by Fv fragment of antibody 8D4.

artículo científico publicado en 2001

M ring, S ring and proximal rod of the flagellar basal body of Salmonella typhimurium are composed of subunits of a single protein, FliF.

artículo científico publicado en 1992

Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu.

artículo científico publicado en 2012

Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma

artículo científico publicado en 2015

Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels

artículo científico publicado en 2016

Naturally arising HIV-1 Nef variants conferring escape from cytotoxic T lymphocytes influence viral entry co-receptor expression and susceptibility to superinfection.

artículo científico publicado en 2010

Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.

artículo científico publicado en 2014

Reconstitution of anti-HIV effector functions of primary human CD8 T lymphocytes by transfer of HIV-specific alphabeta TCR genes

scientific article published on 01 December 2004

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

artículo científico publicado en 2016

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

artículo científico publicado en 2017

Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19

Revealing the peptide presenting process of human leukocyte antigen through the analysis of fluctuation

artículo científico publicado en 2015

Selection of TI8-8V mutant associated with long-term control of HIV-1 by cross-reactive HLA-B*51:01-restricted cytotoxic T cells

artículo científico publicado en 2014

Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules

artículo científico publicado en 2002

Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.

artículo científico publicado en 2018

Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress human immunodeficiency virus type 1 (HIV-1) replication in HIV-1-infected CD4+ T cells and macrophages

artículo científico publicado en 2009

Structural analysis of chick ephrin-A2 by function-blocking and non-blocking monoclonal antibodies.

artículo científico publicado en 2002

Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere.

artículo científico publicado en 2000

Suppressive effect of topically applied CX-659S, a novel diaminouracil derivative, on the contact hypersensitivity reaction in various animal models

scientific article published on 01 December 2000

The Impact of Multidideoxynucleoside Resistance-Conferring Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase on Polymerase Fidelity and Error Specificity ⬇️

artículo científico publicado el 1 de abril de 1998

The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin

artículo científico publicado en 2000

The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement

artículo científico publicado en 2011

The role of hepatitis B virus-specific memory CD8 T cells in the control of viral replication

artículo científico publicado en 2002

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

artículo científico publicado en 2022

Lista de obras de Takamasa Ueno

A phase I trial of the pharmacokinetics, toxicity, and activity of KNI-272, an inhibitor of HIV-1 protease, in patients with AIDS or symptomatic HIV infection

A recurrent large Alu-mediated deletion in the hypoxanthine phosphoribosyltransferase (HPRT1) gene associated with Lesch-Nyhan syndrome.

A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion

Aromatic Side Chain at Position 412 of SERINC5 Exerts Restriction Activity toward HIV-1 and Other Retroviruses

Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection

Attenuation of multiple Nef functions in HIV-1 elite controllers

CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope

CTL-Mediated Selective Pressure Influences Dynamic Evolution and Pathogenic Functions of HIV-1 Nef

Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross-reactivity.

Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay

Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR.

Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths.

Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope

Development of fluoroquinolone resistance and mutations involving GyrA and ParC proteins among Neisseria gonorrhoeae isolates in Japan

Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

Domain structures of the MS ring component protein (FliF) of the flagellar basal body of Salmonella typhimurium.

Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection ⬇️

Dynamic range of Nef functions in chronic HIV-1 infection

Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection

Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages.

Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

Failure of effector function of human CD8+ T Cells in NOD/SCID/JAK3⁻/⁻ immunodeficient mice transplanted with human CD34+ hematopoietic stem cells

Flagellar filament elongation can be impaired by mutations in the hook protein FlgE of Salmonella typhimurium: a possible role of the hook as a passage for the anti-sigma factor FlgM.

Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions.

HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations.

HLA class I-restricted recognition of an HIV-derived epitope peptide by a human T cell receptor alpha chain having a Vdelta1 variable segment.

Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.

Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral activity of HIV-specific CTL.

Impaired Nef function is associated with early control of HIV-1 viremia

Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.

Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety

Inhibition of telomerase by linear-chain fatty acids: a structural analysis.

Inhibition of the hepatitis C virus NS3 protease activity by Fv fragment of antibody 8D4.

M ring, S ring and proximal rod of the flagellar basal body of Salmonella typhimurium are composed of subunits of a single protein, FliF.

Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu.

Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma

Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels

Naturally arising HIV-1 Nef variants conferring escape from cytotoxic T lymphocytes influence viral entry co-receptor expression and susceptibility to superinfection.

Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.

Reconstitution of anti-HIV effector functions of primary human CD8 T lymphocytes by transfer of HIV-specific alphabeta TCR genes

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19

Revealing the peptide presenting process of human leukocyte antigen through the analysis of fluctuation

Selection of TI8-8V mutant associated with long-term control of HIV-1 by cross-reactive HLA-B*51:01-restricted cytotoxic T cells

Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules

Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.

Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress human immunodeficiency virus type 1 (HIV-1) replication in HIV-1-infected CD4+ T cells and macrophages

Structural analysis of chick ephrin-A2 by function-blocking and non-blocking monoclonal antibodies.

Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere.

Suppressive effect of topically applied CX-659S, a novel diaminouracil derivative, on the contact hypersensitivity reaction in various animal models

The Impact of Multidideoxynucleoside Resistance-Conferring Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase on Polymerase Fidelity and Error Specificity ⬇️

The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin

The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement

The role of hepatitis B virus-specific memory CD8 T cells in the control of viral replication

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike