Lista de obras - Antonello Di Paolo - Dominio Público Uruguay

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

artículo científico publicado en 2008

A case report of a TDM-guided optimization of mitotane for a safe and effective long-term treatment

artículo científico publicado en 2019

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

artículo científico publicado en 2008

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

artículo científico publicado en 2008

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

artículo científico publicado en 2006

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

artículo científico publicado en 2004

A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma

scientific article published on 13 September 2011

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

artículo científico publicado en 2010

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

artículo científico publicado en 2009

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

artículo científico publicado en 2001

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

artículo científico publicado en 2004

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

artículo científico publicado en 1999

Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia.

artículo científico publicado en 2017

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

artículo científico publicado en 2002

Cardiovascular implantable electronic device endocarditis treated with daptomycin with or without transvenous removal.

artículo científico publicado en 2012

Case report of a successful treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and MRSA/vancomycin-resistant Enterococcus faecium cholecystitis by daptomycin.

artículo científico publicado en 2011

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

artículo científico publicado en 2002

Chronic administration of suramin induces neurotoxicity in rats.

artículo científico publicado en 1997

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

artículo científico publicado en 1996

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

artículo científico publicado en 2013

Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

artículo científico publicado en 2012

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

scientific article published on 24 July 2013

Daptomycin concentrations in valve tissue and vegetation in patients with bacterial endocarditis

artículo científico publicado en 2012

Different recommendations for daptomycin dosing over time in patients with severe infections

artículo científico publicado en 2014

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

artículo científico publicado en 2010

Drug therapeutic failures in emergency department patients. A university hospital experience.

artículo científico publicado en 2004

EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.

artículo científico publicado en 2013

Fungicidal activity and PK/PD of caspofungin as tools to guide antifungal therapy in a fluconazole-resistant C. parapsilosis candidemia

artículo científico publicado en 2017

Generic Substitution of Orphan Drugs for the Treatment of Rare Diseases: Exploring the Potential Challenges

artículo científico publicado en 2018

Genotype A1/A2 associated with neuroleptic malignant syndrome.

artículo científico publicado en 2005

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

artículo científico publicado en 2005

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

artículo científico publicado en 2006

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

artículo científico publicado en 2001

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

scientific article published on 01 January 1999

Inhibitory effect of the somatostatin analogue SMS 201-995 and cytokines on the proliferation of human colon adenocarcinoma cell lines.

artículo científico publicado en 1995

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

artículo científico publicado en 2006

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

artículo científico publicado en 2011

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

artículo científico publicado en 2009

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

artículo científico publicado en 2002

Linezolid for endocarditis: a case series of 14 patients

scientific article published on 11 January 2011

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

artículo científico publicado en 1999

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

artículo científico

Micafungin for Candida albicans pacemaker-associated endocarditis: a case report and review of the literature

artículo científico publicado en 2012

Oral gentamicin gut decontamination for prevention of KPC-producing Klebsiella pneumoniae infections: relevance of concomitant systemic antibiotic therapy

artículo científico publicado en 2014

Personalized medicine in Europe: not yet personal enough?

artículo científico publicado en 2017

Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer

artículo científico publicado en 2011

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

artículo científico publicado en 2001

Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

artículo científico

Pharmacokinetic interactions between omeprazole/pantoprazole and clarithromycin in health volunteers

artículo científico publicado en 2004

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

artículo científico publicado en 2002

Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily

artículo científico publicado en 2002

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

artículo científico publicado en 2008

Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity

artículo científico publicado en 2012

Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

artículo científico publicado en 2013

Prognostic value of CD133 caused by mutant K-Ras and B-Raf--letter

scientific article published on 18 July 2012

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

artículo científico publicado en 2001

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

artículo científico publicado en 2002

Serotonin syndrome and the T102-->C polymorphism of the 5-HT2A receptor: a case report

artículo científico publicado en 2008

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

artículo científico publicado en 2002

The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia

artículo científico publicado en 2014

The role of thymidylate synthase as a molecular biomarker

scientific article published on 01 January 2004

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

artículo científico publicado en 2006

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

artículo científico publicado en 2011

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia

scientific article published on 01 August 2000

Lista de obras de Antonello Di Paolo

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

A case report of a TDM-guided optimization of mitotane for a safe and effective long-term treatment

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia.

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

Cardiovascular implantable electronic device endocarditis treated with daptomycin with or without transvenous removal.

Case report of a successful treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and MRSA/vancomycin-resistant Enterococcus faecium cholecystitis by daptomycin.

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

Chronic administration of suramin induces neurotoxicity in rats.

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

Daptomycin concentrations in valve tissue and vegetation in patients with bacterial endocarditis

Different recommendations for daptomycin dosing over time in patients with severe infections

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

Drug therapeutic failures in emergency department patients. A university hospital experience.

EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.

Fungicidal activity and PK/PD of caspofungin as tools to guide antifungal therapy in a fluconazole-resistant C. parapsilosis candidemia

Generic Substitution of Orphan Drugs for the Treatment of Rare Diseases: Exploring the Potential Challenges

Genotype A1/A2 associated with neuroleptic malignant syndrome.

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

Inhibitory effect of the somatostatin analogue SMS 201-995 and cytokines on the proliferation of human colon adenocarcinoma cell lines.

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

Linezolid for endocarditis: a case series of 14 patients

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

Micafungin for Candida albicans pacemaker-associated endocarditis: a case report and review of the literature

Oral gentamicin gut decontamination for prevention of KPC-producing Klebsiella pneumoniae infections: relevance of concomitant systemic antibiotic therapy

Personalized medicine in Europe: not yet personal enough?

Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

Pharmacokinetic interactions between omeprazole/pantoprazole and clarithromycin in health volunteers

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity

Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

Prognostic value of CD133 caused by mutant K-Ras and B-Raf--letter

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

Serotonin syndrome and the T102-->C polymorphism of the 5-HT2A receptor: a case report

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia

The role of thymidylate synthase as a molecular biomarker

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia