Filtros de búsqueda

Lista de obras de Rene E Toes

A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8+ T Lymphocytes

article

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

artículo científico publicado en 2007

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis

artículo científico publicado en 2011

A dual function for CD40 agonists

artículo científico publicado en 2000

A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis

artículo científico publicado en 2013

A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis

artículo científico publicado en 2013

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

artículo científico publicado en 2014

A high body mass index has a protective effect on the amount of joint destruction in small joints in early rheumatoid arthritis

artículo científico publicado en 2007

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

artículo científico publicado en 2013

A novel long non-coding RNA in the rheumatoid arthritis risk locus TRAF1-C5 influences C5 mRNA levels.

artículo científico publicado en 2015

A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes

artículo científico publicado en 2016

A prediction rule for disease outcome in patients with Recent-onset undifferentiated arthritis: How to guide individual treatment decisions

scientific article published on 01 February 2007

A rapid isolation procedure for dendritic cells from mouse spleen by centrifugal elutriation

artículo científico publicado en 1992

ACPA (anti-citrullinated protein antibodies) and rheumatoid arthritis.

artículo científico publicado en 2011

Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.

artículo científico publicado en 2015

Ability of Interleukin-33- and Immune Complex-Triggered Activation of Human Mast Cells to Down-Regulate Monocyte-Mediated Immune Responses

article

Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response

Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells

artículo científico publicado en 2013

Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes

artículo científico publicado en 2006

Activation or frustration of anti-tumor responses by T-cell-based immune modulation ⬇️

artículo científico publicado el 1 de octubre de 1997

Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region

artículo científico publicado en 2018

Adipocyte-derived lipids modulate CD4+ T-cell function

artículo científico publicado en 2013

Adipocytes from the infrapatellar fat pad of OA patients modulate CD4+ T cell cytokine production

artículo científico publicado en 2011

Adipocytes modulate the phenotype of human macrophages through secreted lipids

artículo científico publicado en 2013

Adoptive T Cell Immunotherapy of Human Uveal Melanoma Targeting gp100

artículo científico publicado en 2000

Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis

artículo científico publicado en 2009

An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility

artículo científico publicado en 2005

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

artículo científico publicado en 2015

Animal models for arthritis: innovative tools for prevention and treatment

artículo científico publicado en 2011

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

artículo científico publicado en 2014

Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid

scientific article published on 02 October 2020

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

artículo científico publicado en 2013

Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

artículo científico publicado en 2013

Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.

artículo científico publicado en 2015

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent: Fig. 1

article

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage

artículo científico publicado en 2015

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

artículo científico publicado en 2017

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation

artículo científico publicado en 2016

Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles.

artículo científico publicado en 2012

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.

artículo científico publicado en 2011

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

artículo científico publicado en 2013

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

artículo científico publicado en 2015

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

artículo científico publicado en 2010

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

artículo científico publicado en 2010

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

artículo científico publicado en 2009

Anti-cyclic citrullinated peptide antibodies, other common autoantibodies, and smoking as risk factors for lymphoma in patients with rheumatoid arthritis

artículo científico publicado en 2018

Antibodies against collagen type II are not a general marker of acute arthritis onset

artículo científico publicado en 2017

Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications

artículo científico publicado en 2020

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

artículo científico publicado en 2014

Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives

artículo científico publicado en 2010

Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis

artículo científico publicado en 2005

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

artículo científico publicado en 2013

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

artículo científico publicado en 2015

Anticarbamylated protein antibodies can be detected in animal models of arthritis that require active involvement of the adaptive immune system

artículo científico publicado en 2015

Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: comment on the article by Pierer et al.

artículo científico publicado en 2012

Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells

artículo científico publicado en 2004

Antisense long non-coding RNAs are deregulated in skin tissue of patients with systemic sclerosis

artículo científico publicado en 2017

Are ACPA-positive and ACPA-negative RA the same disease?

artículo científico publicado en 2011

Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis?

artículo científico publicado en 2014

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

artículo científico publicado en 2015

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

article

Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population

scientific article published on 01 November 2009

Association of Variants inIL2RAWith Progression of Joint Destruction in Rheumatoid Arthritis

artículo científico publicado en 2013

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

article

Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis

artículo científico publicado en 2009

Association of anti-carbamylated protein antibodies with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

artículo científico publicado en 2015

Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis

artículo científico publicado en 2004

Association of genetic variants in the IL4 and IL4R genes with the severity of joint damage in rheumatoid arthritis: a study in seven cohorts

artículo científico publicado en 2013

Association of smoking with the constitution of the anti-cyclic citrullinated peptide response in the absence of HLA-DRB1 shared epitope alleles.

artículo científico publicado en 2007

Association of the -2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis

article

Association of the CCR5Δ32 variant with juvenile idiopathic arthritis in a meta-analysis.

artículo científico publicado en 2011

Association of the CD226 (DNAM-1) Gly307Ser polymorphism with juvenile idiopathic arthritis.

artículo científico publicado en 2011

Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort.

artículo científico publicado en 2005

Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis.

artículo científico publicado en 2009

Association of tumor necrosis factor α polymorphism and radiographic progression in rheumatoid arthritis: Comment on the article by Khanna et al

artículo científico publicado en 2007

Association of valine and leucine at HLA-DRB1 position 11 with radiographic progression in rheumatoid arthritis, independent of the shared epitope alleles but not independent of anti-citrullinated protein antibodies.

artículo científico publicado en 2015

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

artículo científico publicado en 2011

Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study

artículo científico publicado en 2004

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

artículo científico publicado en 2018

Autoantibody testing to predict response to therapy in RA

article

Autoimmune responses in the rheumatoid synovium.

artículo científico publicado en 2009

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

artículo científico publicado en 2012

B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation

artículo científico publicado en 2017

Barriers to chimerism after major histocompatibility complex-mismatched stem cell transplantation: a potential role for heterologous immunity.

artículo científico publicado en 2014

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

artículo científico publicado en 2018

Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis

artículo científico publicado en 2011

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis.

artículo científico publicado en 2017

Bioorthogonal Antigens Allow The Study Of Intracellular Processing And Presentation Of Post-Translationally Modified Antigens

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.

artículo científico publicado en 2005

C57BL/6 NK cell gene complex is crucially involved in vascular remodeling

artículo científico publicado en 2013

CD226(DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis

scientific article published on 23 July 2014

CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis.

artículo científico publicado en 2003

CD25+ regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis

scientific article published on 01 November 2004

CD4+T Cells Are Able to Promote Tumor Growth through Inhibition of Tumor-Specific CD8+T-Cell Responses in Tumor-Bearing Hosts

article

CTLA-4IG suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPASE mediator of oxidative stress in rheumatoid arthritis T cells

article

Cellular immunity against DNA tumour viruses: possibilities for peptide-based vaccines and immune escape.

artículo científico publicado en 1995

Cellular-based immune modulation in arthritis

artículo científico publicado en 2004

Characterization of an immuno 'stealth' derivative of the herpes simplex virus thymidine-kinase gene.

artículo científico publicado en 2006

Checkpoints controlling the induction of B cell mediated autoimmunity in human autoimmune diseases

scientific article published on 05 November 2020

Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells

artículo científico publicado en 2011

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

artículo científico publicado en 2013

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

artículo científico publicado en 1997

Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNF alpha and IL18 but not CXCL12.

artículo científico publicado en 2005

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

artículo científico

Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis".

artículo científico publicado en 2018

Comment on “Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis”

artículo científico publicado en 2015

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

scientific article published on 14 September 2008

Communication between human mast cells and CD4(+) T cells through antigen-dependent interactions

artículo científico publicado en 2013

Competition inhibition of cytotoxic T-lymphocyte (CTL) lysis, a more sensitive method to identify candidate CTL epitopes than induction of antibody-detected MHC class I stabilization.

artículo científico publicado en 1995

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis

artículo científico publicado en 2009

Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis.

artículo científico publicado en 2008

Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and major histocompatibility complex-mismatched allogeneic bone marrow transplantation

artículo científico publicado en 2004

Correction: A Candidate Gene Approach Identifies the TRAF1/C5 Region as a Risk Factor for Rheumatoid Arthritis

artículo científico publicado en 2007

Correlation between expression of CD44 splice variant v8-v9 and invasiveness of fibroblast-like synoviocytes in an in vitro system.

artículo científico publicado en 2004

Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1.

artículo científico publicado en 2003

Cross-priming of CTL responses in vivo does not require antigenic peptides in the endoplasmic reticulum of immunizing cells

article

Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis

artículo científico publicado en 2015

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

artículo científico publicado en 2008

DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg

artículo científico publicado en 2009

DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4.

artículo científico publicado en 2010

DX5+ CD4+ T cells modulate CD4+ T-cell response via inhibition of IL-12 production by DCs.

artículo científico publicado en 2013

Decreased serum cell-free DNA levels in rheumatoid arthritis.

artículo científico publicado en 2015

Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+ T cells upon immune-complex uptake in vivo

artículo científico publicado en 2006

Dendritic cells: vehicles for tolerance induction and prevention of autoimmune diseases.

artículo científico publicado en 2006

Design and evaluation of antigen-specific vaccination strategies against cancer.

artículo científico publicado en 2000

Detection and Structural Elucidation of Esterified Oxylipids in Human Synovial Fluid by Electrospray Ionization-Fourier Transform Ion-Cyclotron Mass Spectrometry and Liquid Chromatography-Ion Trap-MS3: Detection of Esterified Hydroxylated Docosapenta

artículo científico publicado en 2013

Diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis.

artículo científico publicado en 2009

Differences in synovial tissue infiltrates between anti–cyclic citrullinated peptide–positive rheumatoid arthritis and anti–cyclic citrullinated peptide–negative rheumatoid arthritis

artículo científico publicado en 2008

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

scientific article published on 31 May 2019

Differential TLR-induced cytokine production by human mast cells is amplified by FcɛRI triggering.

artículo científico publicado en 2015

Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study

artículo científico publicado en 2007

Do autoantibody-responses mature between presentation with arthralgia suspicious for progression to rheumatoid arthritis and development of clinically apparent inflammatory arthritis? A longitudinal serological study

artículo científico publicado en 2020

Does immunological remission, defined as disappearance of autoantibodies, occur with current treatment strategies? A long-term follow-up study in rheumatoid arthritis patients who achieved sustained DMARD-free status

artículo científico publicado en 2019

Dysferlin regulates cell adhesion in human monocytes.

artículo científico publicado en 2013

Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes

artículo científico publicado en 2002

Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells.

artículo científico publicado en 2005

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double-blind, randomized, placebo-controlled trial

artículo científico publicado en 2007

Efficient direct priming of tumor-specific cytotoxic T lymphocyte in vivo by an engineered APC.

artículo científico publicado en 1998

Efficient tumor eradication by adoptively transferred cytotoxic T-cell clones in allogeneic hosts

artículo científico publicado en 1996

Enhanced concentrations of interleukin 16 are associated with joint destruction in patients with rheumatoid arthritis.

artículo científico publicado en 2004

Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors

artículo científico publicado en 1996

Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells

artículo científico publicado en 1998

Epistasis between two HLA antigens defines a subset of individuals at a very high risk for ankylosing spondylitis

artículo científico publicado en 2012

Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis.

artículo científico publicado en 2010

Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA.

artículo científico publicado en 2018

Expansion of Th17 Cells by Human Mast Cells Is Driven by Inflammasome-Independent IL-1β.

artículo científico publicado en 2016

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

artículo científico publicado en 2005

Extensive cross-reactivity of CD4+ adenovirus-specific T cells: implications for immunotherapy and gene therapy.

artículo científico publicado en 2003

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

artículo científico publicado en 2015

FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians

artículo científico publicado en 2006

Fc gamma receptor binding profile of anti-citrullinated protein antibodies in immune complexes suggests a role for FcγRI in the pathogenesis of synovial inflammation

artículo científico publicado en 2018

Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation

artículo científico publicado en 2007

Fibroblast-like synoviocytes from patients with rheumatoid arthritis are more sensitive to apoptosis induced by the viral protein, apoptin, than fibroblast-like synoviocytes from trauma patients

artículo científico publicado en 2006

Fibroblast-like synoviocytes from rheumatoid arthritis patients express less FLICE-inhibitory protein than fibroblast-like synoviocytes from trauma patients: Comment on the article by Schedel et al

artículo científico publicado en 2003

Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles.

artículo científico publicado en 2007

Fine-mapping the human leukocyte antigen locus in rheumatoid arthritis and other rheumatic diseases: identifying causal amino acid variants?

artículo científico publicado en 2015

Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue

artículo científico publicado en 2017

Functional killer Ig-like receptors on human memory CD4+ T cells specific for cytomegalovirus.

artículo científico publicado en 2009

Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.

artículo científico publicado en 2004

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

artículo científico publicado en 2007

Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.

artículo científico publicado en 2015

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis

artículo científico publicado en 2013

Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis

artículo científico publicado en 2012

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

artículo científico publicado en 2009

Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: a multicohort study

artículo científico publicado en 2012

Genetic variants in the prediction of rheumatoid arthritis

scientific article published on 03 May 2010

Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis.

artículo científico publicado en 2013

Genetic variation in VTCN1 (B7-H4) is associated with course of disease in juvenile idiopathic arthritis

artículo científico publicado en 2013

Genetic variation of the Fc gamma receptor 3B gene and association with rheumatoid arthritis.

artículo científico publicado en 2010

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Genetics of rheumatoid arthritis: what have we learned?

artículo científico publicado en 2011

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

artículo científico publicado en 2013

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

artículo científico publicado en 2010

Genome-wide single-nucleotide polymorphism studies in rheumatology: hype or hope?

artículo científico publicado en 2008

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

artículo científico publicado en 2010

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

artículo científico publicado en 2015

Guiding the action of the immune system: Interactions between the immune system and non-immune tissues

artículo científico publicado en 2011

HLA and rheumatoid arthritis: how do they connect?

artículo científico

HLA class II and rheumatoid arthritis: the bumpy road of revelation

artículo científico publicado en 2017

HLA-B60 and the HLA-B27/HLA-B60 genotype are not risk factors for acute anterior uveitis.

artículo científico publicado en 2013

High Levels of Adenovirus DNA in Serum Correlate with Fatal Outcome of Adenovirus Infection in Children after Allogeneic Stem‐Cell Transplantation

scientific article published on 31 July 2002

High dose chemotherapy and autologous hematopoietic stem cell transplantation for rheumatoid arthritis: a review.

artículo científico publicado en 2002

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

artículo científico publicado en 2012

How undifferentiated arthritis evolves into chronic arthritis.

artículo científico publicado en 2014

Human CD4+ T cells stimulated by conserved adenovirus 5 hexon peptides recognize cells infected with different species of human adenovirus

artículo científico publicado en 2006

Human mast cells costimulate T cells through a CD28-independent interaction

artículo científico publicado en 2016

IL-17-producing CD4+ T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities

artículo científico publicado en 2014

IL-21 enhances the activity of the TLR-MyD88-STAT3 pathway but not the classical TLR-MyD88-NF-κB pathway in human B cells to boost antibody production

artículo científico publicado en 2013

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis.

artículo científico publicado en 2015

Identification of CXCL13 as a marker for rheumatoid arthritis outcome using an in silico model of the rheumatic joint

article

Identification of Lifelines participants at high risk for development of rheumatoid arthritis

article

Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.

artículo científico publicado en 2013

Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections.

artículo científico publicado en 2014

Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis

artículo científico publicado en 2017

Identification of citrullinated vimentin peptides as T cell epitopes in HLAâ DR4â positive patients with rheumatoid arthritis

scientific article published on 01 January 2010

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression

artículo científico publicado en 2013

IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation.

artículo científico publicado en 2014

IgM antibodies against acetylated proteins as a possible starting point of the anti-modified protein antibody response in rheumatoid arthritis

Immature Dendritic Cells Suppress Collagen-Induced Arthritis by In Vivo Expansion of CD49b+ Regulatory T Cells

artículo científico publicado en 2006

Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.

artículo científico publicado en 2000

Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?

Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

artículo científico publicado en 2004

Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum.

artículo científico publicado en 2008

Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment

article

Immunomodulatory Dendritic Cells Inhibit Th1 Responses and Arthritis via Different Mechanisms

article

Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity ⬇️

artículo científico publicado el 1 de noviembre de 1996

Importance of CD4(+) T helper cell responses in tumor immunity.

artículo científico publicado en 2000

In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway

artículo científico publicado en 2002

In vivo detection of fluorescent tumor-specific cytotoxic T cell clones

artículo científico publicado en 1993

Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance

artículo científico publicado en 2013

Inducing tissue specific tolerance in autoimmune disease with tolerogenic dendritic cells

artículo científico

Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity

artículo científico publicado en 2012

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

artículo científico publicado en 2012

Inflammation functions as a key mediator in the link between ACPA and erosion development: an association study in Clinically Suspect Arthralgia.

artículo científico publicado en 2018

Inflammatory genes TNFα and IL6 display no signs of increased H3K4me3 in circulating monocytes from untreated rheumatoid arthritis patients.

artículo científico publicado en 2017

Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis

artículo científico publicado en 2012

Intraocular tumor antigen drains specifically to submandibular lymph nodes, resulting in an abortive cytotoxic T cell reaction.

artículo científico publicado en 2004

Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10.

artículo científico publicado en 2002

Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis

artículo científico publicado en 2005

Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells

artículo científico publicado en 2001

Isotype distribution of ANTI–CYCLIC citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response

article

Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS

artículo científico publicado en 2012

Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance

artículo científico publicado en 2005

Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies

artículo científico publicado en 2017

Longevity of Antigen Presentation and Activation Status of APC Are Decisive Factors in the Balance Between CTL Immunity Versus Tolerance

scientific article published on 01 September 2001

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG

scholarly article by Jasmin Knopf et al published July 2018 in Journal of Neuroimmunology

Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis.

artículo científico publicado en 2013

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

article

Mast cells in rheumatic disease.

artículo científico

Mechanisms of oral tolerance revisited.

artículo científico publicado en 2008

Mesenchymal stem cells in autoimmune diseases: hype or hope?

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells

artículo científico publicado en 2007

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

artículo científico publicado en 2017

Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo

artículo científico publicado en 2006

N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line

artículo científico publicado en 2024

Natural Killer Cells and CD4 + T-Cells Modulate Collateral Artery Development

article

Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains.

artículo científico publicado en 2010

New biomarkers in rheumatoid arthritis

artículo científico publicado el 1 de noviembre de 2012

Novel genetic association of theVTCN1region with rheumatoid arthritis

artículo científico publicado en 2012

On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis

artículo científico publicado en 2019

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

artículo científico publicado en 2010

Pathogenic effector functions of ACPA: Where do we stand?

artículo científico publicado en 2019

Pathogenic relevance of anti–citrullinated vimentin antibodies: Comment on the article by Montes et al ⬇️

artículo científico publicado el 1 de febrero de 2013

Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

scientific article published on July 1996

Peptide-based cancer vaccines

scientific article published on 01 October 1996

Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

artículo científico publicado en 2020

Persisting NK cell alloreactivity in the presence of long-term stable hematopoietic chimerism

artículo científico publicado en 2009

Pitfalls in the detection of citrullination and carbamylation

artículo científico publicado en 2017

Platelets and autoimmunity.

artículo científico

Possibilities for preventive treatment in rheumatoid arthritis? Lessons from experimental animal models of arthritis: a systematic literature review and meta-analysis.

artículo científico publicado en 2016

Presence of anticitrullinated protein antibodies in a large population-based cohort from the Netherlands.

artículo científico publicado en 2017

Pretreatment serum levels of anti-cyclic citrullinated peptide antibodies are associated with the response to methotrexate in recent-onset arthritis

article

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: Results from two large early arthritis cohorts

artículo científico publicado en 2009

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

artículo científico publicado en 2010

Protection against rheumatoid arthritis by HLA: nature and nurture.

artículo científico publicado en 2008

Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

artículo científico publicado en 1997

Protective antitumor immunity induced by immunization with completely allogeneic tumor cells

scientific article published on 01 August 1996

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA.

artículo científico publicado en 2015

Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

artículo científico publicado en 2009

RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro

artículo científico publicado en 2007

RUNX1 intronic SNP is not associated with rheumatoid arthritis susceptibility in Dutch Caucasians

artículo científico publicado en 2005

Rapid Peptide Turnover and Inefficient Presentation of Exogenous Antigen Critically Limit the Activation of Self-Reactive CTL by Dendritic Cells

artículo científico publicado en 2001

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

artículo científico publicado en 2011

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method

artículo científico publicado en 2012

Redefining the HLA and RA association: to be or not to be anti-CCP positive.

artículo científico publicado en 2005

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins

artículo científico publicado en 2005

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease

artículo científico publicado en 2016

Rejection of intraocular tumors by CD4(+) T cells without induction of phthisis.

artículo científico publicado en 2001

Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue

article

Reply

scientific article published on 09 October 2016

Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation

artículo científico publicado en 2008

Response to: "How to communicate in science" by Klareskog et al

artículo científico publicado en 2019

Response to: 'Acquiring new N-glycosylation sites in variable regions of immunoglobulin genes by somatic hypermutation is a common feature of autoimmune diseases' by Visser et al.

artículo científico publicado en 2017

Response to: 'Comment on editorial 'Pathogenic effector functions of ACPA: where do we stand'' by Holmdahl

scientific article published on 03 July 2019

Rheumatoid arthritis phenotype at presentation differs depending on the number of autoantibodies present.

artículo científico publicado en 2016

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

artículo científico publicado en 2010

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation

artículo científico publicado en 2018

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation.

artículo científico publicado en 2017

Risk of progression from undifferentiated arthritis to rheumatoid arthritis: the effect of the PTPN22 1858T-allele in anti-citrullinated peptide antibody positive patients

scientific article published on 06 March 2007

Rituximab in relapsing Graves' disease, a phase II study.

artículo científico publicado en 2008

Role of Anti-Carbamylated Protein Antibodies Compared to Anti-Citrullinated Protein Antibodies in Indigenous North Americans With Rheumatoid Arthritis, Their First-Degree Relatives, and Healthy Controls.

artículo científico publicado en 2016

Role of TRAIL and IFN-gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye.

artículo científico publicado en 2003

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

artículo científico publicado en 2016

Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans

artículo científico publicado en 2016

Studying associations between variants inTRAF1-C5andTNFAIP3-OLIG3and the progression of joint destruction in rheumatoid arthritis in multiple cohorts

scientific article published on 14 May 2012

Successful immunotherapy of an intraocular tumor in mice.

artículo científico publicado en 1999

Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation

artículo científico publicado en 2022

Synovial fluid mononuclear cells provide an environment for long-term survival of antibody-secreting cells and promote the spontaneous production of anti-citrullinated protein antibodies

artículo científico publicado en 2016

T cell avidity determines the level of CTL activation

artículo científico publicado en 2004

T-cell co-stimulation by CD28-CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development

article

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

artículo científico publicado en 1998

TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells

artículo científico publicado en 2014

TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey

artículo científico publicado en 2011

Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.

artículo científico publicado en 2017

Targeting host B-cell immune responses by persistent donor NK-cell alloreactivity following nonmyeloablative allogeneic stem cell transplantation

article

The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population

scientific article published on 29 November 2006

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

artículo científico publicado en 2011

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

artículo científico publicado en 2018

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

article

The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide

artículo científico publicado en 2007

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus

artículo científico publicado en 2018

The RAGE G82S polymorphism is not associated with rheumatoid arthritis independently of HLA-DRB1*0401

artículo científico publicado en 2006

The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

artículo científico publicado en 2009

The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

artículo científico publicado en 2008

The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis.

artículo científico publicado en 2008

The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis: a study exploring replication and the added value to ACPA and rheumatoid factor

artículo científico publicado en 2016

The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations

artículo científico publicado en 2013

The contribution of autoantibodies to post-translationally modified proteins to inflammatory arthritis.

artículo científico publicado en 2016

The extensive glycosylation of the ACPA variable domain observed for ACPA-IgG is absent from ACPA-IgM

artículo científico publicado en 2017

The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor

artículo científico publicado en 2000

The human 26 S and 20 S proteasomes generate overlapping but different sets of peptide fragments from a model protein substrate

artículo científico publicado en 2000

The increased ability to present citrullinated peptides is not unique to HLA-SE molecules: arginine-to-citrulline conversion also enhances peptide affinity for HLA-DQ molecules

artículo científico publicado en 2016

The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis

artículo científico publicado en 2008

The influence of ACPA status and characteristics on the course of RA.

artículo científico

The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype.

artículo científico publicado en 2011

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

artículo científico publicado en 2017

The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)

artículo científico publicado en 2011

The pathogenic potential of autoreactive antibodies in rheumatoid arthritis.

artículo científico publicado en 2014

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical.

artículo científico publicado en 2017

The problems and promises of research into human immunology and autoimmune disease

artículo científico publicado en 2012

The production and secretion of complement component C1q by human mast cells

artículo científico publicado en 2016

The risk of individual autoantibodies, autoantibody combinations and levels for arthritis development in clinically suspect arthralgia.

artículo científico publicado en 2017

The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis

artículo científico publicado en 2016

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

artículo científico publicado en 2015

The tumoricidal activity of memory CD8+ T cells is hampered by persistent systemic antigen, but full functional capacity is regained in an antigen-free environment

artículo científico publicado en 2004

The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics

artículo científico publicado en 2011

Tic-tac-toe does not provide lessons for appreciating the HLA-rheumatoid arthritis relationship: Comment on the editorial by Bridges et al

artículo científico publicado en 2008

Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies

scientific article published on 12 May 2014

Toward a data-driven evaluation of the 2010 American College of Rheumatology/European League Against Rheumatism criteria for rheumatoid arthritis: is it sensible to look at levels of rheumatoid factor?

artículo científico publicado en 2011

Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level

artículo científico publicado en 2004

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

scientific article published on 01 January 2007

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis

artículo científico publicado en 2018

Update on autoantibodies to modified proteins.

artículo científico publicado en 2015

Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice.

artículo científico publicado en 2009

Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis a

artículo científico publicado en 2009

Variable domain glycosylation of ACPA-IgG: A missing link in the maturation of the ACPA response?

artículo científico publicado en 2017

Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis

artículo científico publicado en 2011

Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity

artículo científico publicado en 2016

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda